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Researcher
Pieter Rondou
Profile
Projects
Publications
Activities
Awards & Distinctions
52
Results
2018
A high-throughput 3’ UTR reporter screening identifies microRNA interactomes of cancer genes
Gert Van Peer
Evelien Mets
Shana Claeys
Ines De Punt
Steve Lefever
Maté Ongenaert
Pieter Rondou
Franki Speleman
Pieter Mestdagh
Jo Vandesompele
A1
Journal Article
in
PLOS ONE
2018
2017
Deciphering the untranslated message in T-cell acute lymphoblastic leukemia
Annelynn Wallaert
Franki Speleman
Pieter Van Vlierberghe
Pieter Rondou
Dissertation
2017
Regulation of G protein-coupled receptors by ubiquitination
Kamila Skieterska
Pieter Rondou
Kathleen Van Craenenbroeck
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2017
2016
CRISPR-Cas9 modeling of cell lines and zebrafish to study the TLX1-PHF6 cooperative interrelationship in T-cell acute lymphoblastic leukemia
Siebe Loontiens
Kaat Durinck
Nina De Rocker
Annekatrien Boel
Els Janssens
Suzanne Vanhauwaert
Pieter Rondou
Charles De Bock
Inge Van de Walle
Finola Moore
et al.
C3
Conference
2016
Characterization of the interaction between the dopamine D4 receptor, KLHL12 and β-arrestins
Kamila Skieterska
Ao Shen
Dorien Clarisse
Pieter Rondou
Dasiel Oscar Borroto-Escuela
Béatrice Lintermans
Kjell Fuxe
Yang Kevin Xiang
Kathleen Van Craenenbroeck
A1
Journal Article
in
CELLULAR SIGNALLING
2016
Expanding the TLX1 regulome in T-cell acute lymphoblastic leukemia towards long noncoding RNAs
Kaat Durinck
Wouter Van Loocke
Inge Van de Walle
Joni Van der Meulen
Pieter-Jan Volders
Nadine Van Roy
Yves Benoit
Bruce Poppe
Pieter Mestdagh
Jo Vandesompele
et al.
C3
Conference
2016
Long noncoding RNA signatures define oncogenic subtypes in T-cell acute lymphoblastic leukemia
Annelynn Wallaert
Kaat Durinck
Wouter Van Loocke
Inge Van de Walle
Filip Matthijssens
Pieter-Jan Volders
Francisco Avila Cobos
Dries Rombaut
Pieter Rondou
Pieter Mestdagh
et al.
A1
Journal Article
in
LEUKEMIA
2016
Modeling the TLX1-PHF6 cooperative interrelationship in T-cell acute lymphoblastic leukemia in zebrafish
Siebe Loontiens
Kaat Durinck
ELS JANSSENS
Suzanne Vanhauwaert
Pieter Rondou
Jan Cools
Charles De Bock
Inge Van de Walle
Finola Moore
David Langenau
et al.
C3
Conference
2016
RPPA-Based protein profiling reveals enhanced PI3K/AKT/mTOR signaling in ETV6/RUNX1-positive acute lymphoblastic leukemia patients with low CD200 expression
Farzaneh Ghazavi
Valentina Serafin
Pieter Rondou
Tim Lammens
Franki Speleman
Benedetta Accordi
Barbara De Moerloose
Pieter Van Vlierberghe
C3
Conference
2016
The T-ALL oncogene TLX1 controls enhancer lncRNA expression
Karen Verboom
Kaat Durinck
Wouter Van Loocke
Filip Matthijssens
Inge Van de Walle
Annelynn Wallaert
Pieter-Jan Volders
Nadine Van Roy
Yves Benoit
Bruce Poppe
et al.
C3
Conference
2016
2015
Characterization of the genome-wide TLX1 binding profile in T-cell acute lymphoblastic leukemia
Kaat Durinck
Wouter Van Loocke
Joni Van der Meulen
Inge Van de Walle
Maté Ongenaert
Pieter Rondou
Annelynn Wallaert
CE de Bock
Nadine Van Roy
Bruce Poppe
et al.
A1
Journal Article
in
LEUKEMIA
2015
KLHL12 promotes non-lysine ubiquitination of the dopamine receptors D-4.2 and D-4.4, but not of the ADHD-associated D-4.7 variant
Kamila Skieterska
Pieter Rondou
Béatrice Lintermans
Kathleen Van Craenenbroeck
A1
Journal Article
in
PLOS ONE
2015
MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia
Evelien Mets
Joni Van der Meulen
Gert Van Peer
Michael Boice
Pieter Mestdagh
Inge Van de Walle
Tim Lammens
Steven Goossens
Barbara De Moerloose
Yves Benoit
et al.
A1
Journal Article
in
LEUKEMIA
2015
Novel biological insights in T-cell acute lymphoblastic leukemia
Kaat Durinck
Steven Goossens
Sofie Peirs
Annelynn Wallaert
Wouter Van Loocke
Filip Matthijssens
Tim Pieters
Gloria Milani
Tim Lammens
Pieter Rondou
et al.
A1
Journal Article
in
EXPERIMENTAL HEMATOLOGY
2015
The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia
Joni Van der Meulen
Viraj Sanghvi
Konstantinos Mavrakis
Kaat Durinck
Fang Fang
Filip Matthijssens
Pieter Rondou
Monica Rosen
Tim Pieters
Peter Vandenberghe
et al.
A1
Journal Article
in
BLOOD
2015
Transcriptional antagonism between the cooperative oncogenes TLX1 and NOTCH1 in T-cell acute lymphoblastic leukemia.
Kaat Durinck
Wouter Van Loocke
Joni Van der Meulen
Inge Van de Walle
Pieter Rondou
Charles E De Bock
Bruce Poppe
Jan Cools
Jean Soulier
Tom Taghon
et al.
C3
Conference
2015
ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling
Steven Goossens
Enrico Radaelli
Odile Blanchet
Kaat Durinck
Joni Van der Meulen
Sofie Peirs
Tom Taghon
Cedric S Tremblay
Magdaline Costa
Morvarid Farhang Ghahremani
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2015
2014
Characterization of a set of tumor suppressor microRNAs in T cell acute lymphoblastic leukemia
Viraj R Sanghvi
Konstantinos J Mavrakis
Joni Van der Meulen
Michael Boice
Andrew L Wolfe
Mark Carty
Prathibha Mohan
Pieter Rondou
Nicholas D Socci
Yves Benoit
et al.
A1
Journal Article
in
SCIENCE SIGNALING
2014
Expressed repeat elements improve RT-qPCR normalization across a wide range of zebrafish gene expression studies
Suzanne Vanhauwaert
Gert Van Peer
Ali Rihani
Els Janssens
Pieter Rondou
Steve Lefever
Anne De Paepe
Paul Coucke
Franki Speleman
Jo Vandesompele
et al.
A1
Journal Article
in
PLOS ONE
2014
Integrative analysis of the NOTCH1 regulatory network identifies key downstream lncRNAs in acute T-cell lymphoblastic leukemia and normal T-cell development
Annelynn Wallaert
Kaat Durinck
Pieter Rondou
Inge Van de Walle
Wouter Van Loocke
Pieter-Jan Volders
Maté Ongenaert
Nadine Van Roy
Bruce Poppe
Yves Benoit
et al.
C3
Conference
2014
LncRNA profiling in T-cell acute lymphoblastic leukemia predicts a functional connection between lncRNAs and the major T-ALL genetic subgroups
Annelynn Wallaert
Kaat Durinck
Wouter Van Loocke
Pieter-Jan Volders
Yves Benoit
Bruce Poppe
Pieter Mestdagh
Jo Vandesompele
Jean Soulier
Jan Cools
et al.
C3
Conference
2014
MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia
Evelien Mets
Gert Van Peer
Joni Van der Meulen
Michael Boice
Tom Taghon
Steven Goossens
Pieter Mestdagh
Yves Benoit
Barbara De Moerloose
Nadine Van Roy
et al.
A1
Journal Article
in
HAEMATOLOGICA
2014
Non-degradative and non-lysine mediated ubiquitination of the dopamine D4 receptor
Kamila Skieterska
Pieter Rondou
Béatrice Lintermans
Kathleen Van Craenenbroeck
C3
Conference
2014
Phf6 plays a role in hematopoiesis and thymopoiesis in zebrafish
Els Janssens
Suzanne Vanhauwaert
Andy Willaert
Kaat Durinck
Anne De Paepe
Pieter Van Vlierberghe
Pieter Rondou
Franki Speleman
C3
Conference
2014
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer
Andrew L Wolfe
Kamini Singh
Yi Zhong
Philipp Drewe
Vinagolu K Rajasekhar
Viraj R Sanghvi
Konstantinos J Mavrakis
Man Jiang
Justine E Roderick
Joni Van der Meulen
et al.
A1
Journal Article
in
NATURE
2014
The NOTCH1 driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia
Annelynn Wallaert
Kaat Durinck
Pieter Rondou
Inge Van de Walle
Wouter Vanloocke
Pieter-Jan Volders
Suzanne Vanhauwaert
Ellen Geerdens
Maté Ongenaert
Nadine Van Roy
et al.
C3
Conference
2014
The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia
Kaat Durinck
Annelynn Wallaert
Inge Van de Walle
Wouter Van Loocke
Pieter-Jan Volders
Suzanne Vanhauwaert
Ellen Geerdens
Yves Benoit
Nadine Van Roy
Bruce Poppe
et al.
A1
Journal Article
in
HAEMATOLOGICA
2014
The first lncRNA landscape of major genetic T-ALL subsets and guilt-by-association analysis for ETP-ALL specific lncRNAs
Annelynn Wallaert
Kaat Durinck
Wouter Van Loocke
Pieter-Jan Volders
Inge Van de Walle
Yves Benoit
Bruce Poppe
Jo Vandesompele
Tom Taghon
Jean Soulier
et al.
C3
Conference
2014
Unique lncRNA signatures mark the major T-ALL genetic subgroups
Annelynn Wallaert
Kaat Durinck
Wouter Van Loocke
Pieter-Jan Volders
Yves Benoit
Bruce Poppe
Pieter Mestdagh
Jo Vandesompele
Jean Soulier
Jan Cools
et al.
C3
Conference
2014
2013
EVI1 inhibits apoptosis induced by antileukemic drugs via upregulation of CDKN1A/p21/WAF in human myeloid cells
Anna Rommer
Birgit Steinmetz
Friederike Herbst
Hubert Hackl
Petra Heffeter
Daniela Heilos
Martin Filipits
Katarina Steinleitner
Shayda Hemmati
Irene Herbacek
et al.
A1
Journal Article
in
PLOS ONE
2013
Effective Alu repeat based RT-qPCR normalization in cancer cell perturbation experiments
Ali Rihani
Tom Van Maerken
Filip Pattyn
Gert Van Peer
Anneleen Beckers
Sara De Brouwer
Candy Kumps
Evelien Mets
Joni Van der Meulen
Pieter Rondou
et al.
A1
Journal Article
in
PLOS ONE
2013
Expanding the TLX1 regulate in T-cell acute lymphoblastic leukemia towards long non-coding RNAs
Kaat Durinck
Joni Van der Meulen
Maté Ongenaert
Pieter-Jan Volders
Annelynn Wallaert
Nadine Van Roy
Yves Benoit
Bruce Poppe
Pieter Mestdagh
Jo Vandesompele
et al.
C3
Conference
2013
Expanding the TLX1-regulome in T cell acute lymphoblastic leukemia towards long non-coding RNAs
Kaat Durinck
Joni Van der Meulen
Maté Ongenaert
Pieter-Jan Volders
Annelynn Wallaert
Nadine Van Roy
Yves Benoit
Bruce Poppe
Pieter Mestdagh
Jo Vandesompele
et al.
C3
Conference
2013
MiR-128 is a novel PHF6 targeting regulatory non-coding RNA acting as a T-ALL oncogene
Evelien Mets
Joni Van der Meulen
Gert Van Peer
Michael Boice
Pieter Mestdagh
Tom Taghon
David Avran
Barbara De Moerloose
Yves Benoit
Bruce Poppe
et al.
C3
Conference
2013
Novel TAL1 targets beyond protein-coding genes: identification of TAL1-regulated microRNAs in T-cell acute lymphoblastic leukemia
Nadia C Correia
Kaat Durinck
AP Leite
Maté Ongenaert
Pieter Rondou
Franki Speleman
FJ Enquita
João T Barata
A1
Journal Article
in
LEUKEMIA
2013
Role of non-degradative ubiquitination of the dopamine D4 receptor
Kamila Skieterska
Pieter Rondou
Dasiel O Borroto-Escuela
Béatrice Lintermans
Kjell Fuxe
Kathleen Van Craenenbroeck
C3
Conference
2013
The need for transparency and good practices in the qPCR literature
Stephen A Bustin
Vladimir Benes
Jeremy Garson
Jan Hellemans
Jim Huggett
Mikael Kubista
Reinhold Mueller
Tania Nolan
Michael W Pfaffl
Gregory Shipley
et al.
A1
Journal Article
in
NATURE METHODS
2013
2012
Functional relevance of the KLHL12-mediated D4 dopamine receptor ubiquitination
Kamila Skieterska
Pieter Rondou
Dasiel Oscar Borroto-Escuela
Dorien Clarisse
Béatrice Lintermans
Guy Haegeman
Kjell Fuxe
Kathleen Van Craenenbroeck
C3
Conference
2012
On the track of function of KLHL12-mediated dopamine D4 receptor ubiquitination
Kamila Skieterska
Pieter Rondou
Dasiel Oscar Borroto-Escuela
Dorien Clarisse
Béatrice Lintermans
Guy Haegeman
Kjell Fuxe
Kathleen Van Craenenbroeck
C3
Conference
2012
On the track of function of KLHL12-mediated dopamine D4 receptor ubiquitination
Kamila Skieterska
Pieter Rondou
Dasiel Oscar Borroto-Escuela
Dorien Clarisse
Béatrice Lintermans
Guy Haegeman
Kjell Fuxe
Kathleen Van Craenenbroeck
C3
Conference
2012
2011
A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL)
Konstantinos J Mavrakis
Joni Van der Meulen
Andrew L Wolfe
Xiaoping Liu
Evelien Mets
Tom Taghon
Aly A Khan
Manu Setty
Pieter Rondou
Peter Vandenberghe
et al.
A1
Journal Article
in
NATURE GENETICS
2011
A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL)
Evelien Mets
Joni Van der Meulen
Konstantinos J Mavrakis
Andrew L Wolfe
Tom Taghon
Aly A Khan
Manu Setty
Xiaoping Liu
Pieter Rondou
Peter Vandenberghe
et al.
C3
Conference
2011
Cooperative miRNA mediated FBXW7 suppression contributes to T-cell lymphoblastic leukemogenesis
Evelien Mets
Joni Van der Meulen
Konstantinos J Mavrakis
Andrew L Wolfe
Tom Taghon
Aly A Khan
Manu Setty
Xiaoping Liu
Peter Vandenberghe
Eric Delabesse
et al.
C3
Conference
2011
Dopamine D-4 receptor oligomerization: contribution to receptor biogenesis
Kathleen Van Craenenbroeck
Dasiel O Borroto-Escuela
Wilber Romero-Fernandez
Kamila Skieterska
Pieter Rondou
Béatrice Lintermans
Peter Vanhoenacker
Kjell Fuxe
Francisco Ciruela
Guy Haegeman
A1
Journal Article
in
FEBS JOURNAL
2011
EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells
An De Weer
Joni Van der Meulen
Pieter Rondou
Tom Taghon
Torsten A Konrad
Katleen De Preter
Pieter Mestdagh
Tom Van Maerken
Nadine Van Roy
Marta Jeison
et al.
A1
Journal Article
in
BRITISH JOURNAL OF HAEMATOLOGY
2011
IL-1 beta potently stabilizes IL-6 mRNA in human astrocytes
Anneleen Spooren
Pieter Mestdagh
Pieter Rondou
Krzysztof Kolmus
Guy Haegeman
Sarah Gerlo
A1
Journal Article
in
BIOCHEMICAL PHARMACOLOGY
2011
Regulatory networks governed by microRNAs in T-ALL oncogenesis and normal T-cell development
Joni Van der Meulen
Evelien Mets
Pieter Mestdagh
Peter Pipelers
Tom Taghon
David Camacho Trujillo
David Avran
Gert Van Peer
Nadine Van Roy
Olivier Thas
et al.
C3
Conference
2011
2010
KLHL12-mediated ubiquitination of the dopamine D4 receptor does not target the receptor for degradation
Pieter Rondou
Kamila Skieterska
Ann Packeu
Béatrice Lintermans
Peter Vanhoenacker
Georges Vauquelin
Guy Haegeman
Kathleen Van Craenenbroeck
A1
Journal Article
in
CELLULAR SIGNALLING
2010
Resistance of the dopamine D4 receptor to agonist-induced internalization and degradation
Anneleen Spooren
Pieter Rondou
Katarzyna Debowska
Béatrice Lintermans
Linda Vermeulen
Bart Samyn
Kamila Skieterska
Griet Debyser
Bart Devreese
Peter Vanhoenacker
et al.
A1
Journal Article
in
CELLULAR SIGNALLING
2010
The dopamine D4 receptor: biochemical and signalling properties
Pieter Rondou
Guy Haegeman
Kathleen Van Craenenbroeck
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2010
2009
The role of KLHL12 in the signalling and the regulation of the dopamine D4 receptor
Pieter Rondou
Guy Haegeman
Dissertation
2009
2008
BTB protein KLHL12 targets the dopamine D4 receptor for ubiquitination by a Cul3-based E3 ligase
Pieter Rondou
Guy Haegeman
Peter Vanhoenacker
Kathleen Van Craenenbroeck
A1
Journal Article
in
JOURNAL OF BIOLOGICAL CHEMISTRY
2008