Research Explorer

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Researcher

Pieter Rondou

53 Results

2018

A high-throughput 3’ UTR reporter screening identifies microRNA interactomes of cancer genes

Gert Van PeerEvelien MetsShana ClaeysInes De PuntSteve LefeverMaté OngenaertPieter RondouFranki SpelemanPieter MestdaghJo Vandesompele

A1 Journal Article in PLOS ONE

2017

Deciphering the untranslated message in T-cell acute lymphoblastic leukemia

Annelynn WallaertFranki SpelemanPieter Van VlierberghePieter Rondou

Regulation of G protein-coupled receptors by ubiquitination

Kamila SkieterskaPieter RondouKathleen Van Craenenbroeck

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

2016

CRISPR-Cas9 modeling of cell lines and zebrafish to study the TLX1-PHF6 cooperative interrelationship in T-cell acute lymphoblastic leukemia

Siebe LoontiensKaat DurinckNina De RockerAnnekatrien BoelEls JanssensSuzanne VanhauwaertPieter RondouCharles De BockInge Van de WalleFinola Moore et al.

Characterization of the interaction between the dopamine D4 receptor, KLHL12 and β-arrestins

Kamila SkieterskaAo ShenDorien ClarissePieter RondouDasiel Oscar Borroto-EscuelaBéatrice LintermansKjell FuxeYang Kevin XiangKathleen Van Craenenbroeck

A1 Journal Article in CELLULAR SIGNALLING

Expanding the TLX1 regulome in T-cell acute lymphoblastic leukemia towards long noncoding RNAs

Kaat DurinckWouter Van LoockeInge Van de WalleJoni Van der MeulenPieter-Jan VoldersNadine Van RoyYves BenoitBruce PoppePieter MestdaghJo Vandesompele et al.

Long noncoding RNA signatures define oncogenic subtypes in T-cell acute lymphoblastic leukemia

Annelynn WallaertKaat DurinckWouter Van LoockeInge Van de WalleFilip MatthijssensPieter-Jan VoldersFrancisco Avila CobosDries RombautPieter RondouPieter Mestdagh et al.

A1 Journal Article in LEUKEMIA

Modeling the TLX1-PHF6 cooperative interrelationship in T-cell acute lymphoblastic leukemia in zebrafish

Siebe LoontiensKaat DurinckELS JANSSENSSuzanne VanhauwaertPieter RondouJan CoolsCharles De BockInge Van de WalleFinola MooreDavid Langenau et al.

RPPA-Based protein profiling reveals enhanced PI3K/AKT/mTOR signaling in ETV6/RUNX1-positive acute lymphoblastic leukemia patients with low CD200 expression

Farzaneh GhazaviValentina SerafinPieter RondouTim LammensFranki SpelemanBenedetta AccordiBarbara De MoerloosePieter Van Vlierberghe

The T-ALL oncogene TLX1 controls enhancer lncRNA expression

Karen VerboomKaat DurinckWouter Van LoockeFilip MatthijssensInge Van de WalleAnnelynn WallaertPieter-Jan VoldersNadine Van RoyYves BenoitBruce Poppe et al.

2015

Characterization of the genome-wide TLX1 binding profile in T-cell acute lymphoblastic leukemia

Kaat DurinckWouter Van LoockeJoni Van der MeulenInge Van de WalleMaté OngenaertPieter RondouAnnelynn WallaertCE de BockNadine Van RoyBruce Poppe et al.

A1 Journal Article in LEUKEMIA

KLHL12 promotes non-lysine ubiquitination of the dopamine receptors D-4.2 and D-4.4, but not of the ADHD-associated D-4.7 variant

Kamila SkieterskaPieter RondouBéatrice LintermansKathleen Van Craenenbroeck

A1 Journal Article in PLOS ONE

MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia

Evelien MetsJoni Van der MeulenGert Van PeerMichael BoicePieter MestdaghInge Van de WalleTim LammensSteven GoossensBarbara De MoerlooseYves Benoit et al.

A1 Journal Article in LEUKEMIA

Novel biological insights in T-cell acute lymphoblastic leukemia

Kaat DurinckSteven GoossensSofie PeirsAnnelynn WallaertWouter Van LoockeFilip MatthijssensTim PietersGloria MilaniTim LammensPieter Rondou et al.

A1 Journal Article in EXPERIMENTAL HEMATOLOGY

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

Joni Van der MeulenViraj SanghviKonstantinos MavrakisKaat DurinckFang FangFilip MatthijssensPieter RondouMonica RosenTim PietersPeter Vandenberghe et al.

A1 Journal Article in BLOOD

Transcriptional antagonism between the cooperative oncogenes TLX1 and NOTCH1 in T-cell acute lymphoblastic leukemia.

Kaat DurinckWouter Van LoockeJoni Van der MeulenInge Van de WallePieter RondouCharles E De BockBruce PoppeJan CoolsJean SoulierTom Taghon et al.

ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling

Steven GoossensEnrico RadaelliOdile BlanchetKaat DurinckJoni Van der MeulenSofie PeirsTom TaghonCedric S TremblayMagdaline CostaMorvarid Farhang Ghahremani et al.

A1 Journal Article in NATURE COMMUNICATIONS

2014

Characterization of a set of tumor suppressor microRNAs in T cell acute lymphoblastic leukemia

Viraj R SanghviKonstantinos J MavrakisJoni Van der MeulenMichael BoiceAndrew L WolfeMark CartyPrathibha MohanPieter RondouNicholas D SocciYves Benoit et al.

A1 Journal Article in SCIENCE SIGNALING

Expressed repeat elements improve RT-qPCR normalization across a wide range of zebrafish gene expression studies

Suzanne VanhauwaertGert Van PeerAli RihaniEls JanssensPieter RondouSteve LefeverAnne De PaepePaul CouckeFranki SpelemanJo Vandesompele et al.

A1 Journal Article in PLOS ONE

Integrative analysis of the NOTCH1 regulatory network identifies key downstream lncRNAs in acute T-cell lymphoblastic leukemia and normal T-cell development

Annelynn WallaertKaat DurinckPieter RondouInge Van de WalleWouter Van LoockePieter-Jan VoldersMaté OngenaertNadine Van RoyBruce PoppeYves Benoit et al.

LncRNA profiling in T-cell acute lymphoblastic leukemia predicts a functional connection between lncRNAs and the major T-ALL genetic subgroups

Annelynn WallaertKaat DurinckWouter Van LoockePieter-Jan VoldersYves BenoitBruce PoppePieter MestdaghJo VandesompeleJean SoulierJan Cools et al.

MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia

Evelien MetsGert Van PeerJoni Van der MeulenMichael BoiceTom TaghonSteven GoossensPieter MestdaghYves BenoitBarbara De MoerlooseNadine Van Roy et al.

A1 Journal Article in HAEMATOLOGICA

Non-degradative and non-lysine mediated ubiquitination of the dopamine D4 receptor

Kamila SkieterskaPieter RondouBéatrice LintermansKathleen Van Craenenbroeck

Phf6 plays a role in hematopoiesis and thymopoiesis in zebrafish

Els JanssensSuzanne VanhauwaertAndy WillaertKaat DurinckAnne De PaepePieter Van VlierberghePieter RondouFranki Speleman

RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer

Andrew L WolfeKamini SinghYi ZhongPhilipp DreweVinagolu K RajasekharViraj R SanghviKonstantinos J MavrakisMan JiangJustine E RoderickJoni Van der Meulen et al.

A1 Journal Article in NATURE

The NOTCH1 driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia

Annelynn WallaertKaat DurinckPieter RondouInge Van de WalleWouter VanloockePieter-Jan VoldersSuzanne VanhauwaertEllen GeerdensMaté OngenaertNadine Van Roy et al.

The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia

Kaat DurinckAnnelynn WallaertInge Van de WalleWouter Van LoockePieter-Jan VoldersSuzanne VanhauwaertEllen GeerdensYves BenoitNadine Van RoyBruce Poppe et al.

A1 Journal Article in HAEMATOLOGICA

The first lncRNA landscape of major genetic T-ALL subsets and guilt-by-association analysis for ETP-ALL specific lncRNAs

Annelynn WallaertKaat DurinckWouter Van LoockePieter-Jan VoldersInge Van de WalleYves BenoitBruce PoppeJo VandesompeleTom TaghonJean Soulier et al.

Unique lncRNA signatures mark the major T-ALL genetic subgroups

Annelynn WallaertKaat DurinckWouter Van LoockePieter-Jan VoldersYves BenoitBruce PoppePieter MestdaghJo VandesompeleJean SoulierJan Cools et al.

2013

EVI1 inhibits apoptosis induced by antileukemic drugs via upregulation of CDKN1A/p21/WAF in human myeloid cells

Anna RommerBirgit SteinmetzFriederike HerbstHubert HacklPetra HeffeterDaniela HeilosMartin FilipitsKatarina SteinleitnerShayda HemmatiIrene Herbacek et al.

A1 Journal Article in PLOS ONE

Effective Alu repeat based RT-qPCR normalization in cancer cell perturbation experiments

Ali RihaniTom Van MaerkenFilip PattynGert Van PeerAnneleen BeckersSara De BrouwerCandy KumpsEvelien MetsJoni Van der MeulenPieter Rondou et al.

A1 Journal Article in PLOS ONE

Expanding the TLX1 regulate in T-cell acute lymphoblastic leukemia towards long non-coding RNAs

Kaat DurinckJoni Van der MeulenMaté OngenaertPieter-Jan VoldersAnnelynn WallaertNadine Van RoyYves BenoitBruce PoppePieter MestdaghJo Vandesompele et al.

Expanding the TLX1-regulome in T cell acute lymphoblastic leukemia towards long non-coding RNAs

Kaat DurinckJoni Van der MeulenMaté OngenaertPieter-Jan VoldersAnnelynn WallaertNadine Van RoyYves BenoitBruce PoppePieter MestdaghJo Vandesompele et al.

MiR-128 is a novel PHF6 targeting regulatory non-coding RNA acting as a T-ALL oncogene

Evelien MetsJoni Van der MeulenGert Van PeerMichael BoicePieter MestdaghTom TaghonDavid AvranBarbara De MoerlooseYves BenoitBruce Poppe et al.

Novel TAL1 targets beyond protein-coding genes: identification of TAL1-regulated microRNAs in T-cell acute lymphoblastic leukemia

Nadia C CorreiaKaat DurinckAP LeiteMaté OngenaertPieter RondouFranki SpelemanFJ EnquitaJoão T Barata

A1 Journal Article in LEUKEMIA

Role of non-degradative ubiquitination of the dopamine D-4 receptor

Kamila SkieterskaPieter RondouDO Borroto-EscuelaBéatrice LintermansK FuxeKathleen Van Craenenbroeck

Role of non-degradative ubiquitination of the dopamine D4 receptor

Kamila SkieterskaPieter RondouDasiel O Borroto-EscuelaBéatrice LintermansKjell FuxeKathleen Van Craenenbroeck

The need for transparency and good practices in the qPCR literature

Stephen A BustinVladimir BenesJeremy GarsonJan HellemansJim HuggettMikael KubistaReinhold MuellerTania NolanMichael W PfafflGregory Shipley et al.

A1 Journal Article in NATURE METHODS

2012

Functional relevance of the KLHL12-mediated D4 dopamine receptor ubiquitination

Kamila SkieterskaPieter RondouDasiel Oscar Borroto-EscuelaDorien ClarisseBéatrice LintermansGuy HaegemanKjell FuxeKathleen Van Craenenbroeck

On the track of function of KLHL12-mediated dopamine D4 receptor ubiquitination

Kamila SkieterskaPieter RondouDasiel Oscar Borroto-EscuelaDorien ClarisseBéatrice LintermansGuy HaegemanKjell FuxeKathleen Van Craenenbroeck

On the track of function of KLHL12-mediated dopamine D4 receptor ubiquitination

Kamila SkieterskaPieter RondouDasiel Oscar Borroto-EscuelaDorien ClarisseBéatrice LintermansGuy HaegemanKjell FuxeKathleen Van Craenenbroeck

2011

A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL)

Konstantinos J MavrakisJoni Van der MeulenAndrew L WolfeXiaoping LiuEvelien MetsTom TaghonAly A KhanManu SettyPieter RondouPeter Vandenberghe et al.

A1 Journal Article in NATURE GENETICS

A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL)

Evelien MetsJoni Van der MeulenKonstantinos J MavrakisAndrew L WolfeTom TaghonAly A KhanManu SettyXiaoping LiuPieter RondouPeter Vandenberghe et al.

Cooperative miRNA mediated FBXW7 suppression contributes to T-cell lymphoblastic leukemogenesis

Evelien MetsJoni Van der MeulenKonstantinos J MavrakisAndrew L WolfeTom TaghonAly A KhanManu SettyXiaoping LiuPeter VandenbergheEric Delabesse et al.

Dopamine D-4 receptor oligomerization: contribution to receptor biogenesis

Kathleen Van CraenenbroeckDasiel O Borroto-EscuelaWilber Romero-FernandezKamila SkieterskaPieter RondouBéatrice LintermansPeter VanhoenackerKjell FuxeFrancisco CiruelaGuy Haegeman

A1 Journal Article in FEBS JOURNAL

EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells

An De WeerJoni Van der MeulenPieter RondouTom TaghonTorsten A KonradKatleen De PreterPieter MestdaghTom Van MaerkenNadine Van RoyMarta Jeison et al.

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

IL-1 beta potently stabilizes IL-6 mRNA in human astrocytes

Anneleen SpoorenPieter MestdaghPieter RondouKrzysztof KolmusGuy HaegemanSarah Gerlo

A1 Journal Article in BIOCHEMICAL PHARMACOLOGY

Regulatory networks governed by microRNAs in T-ALL oncogenesis and normal T-cell development

Joni Van der MeulenEvelien MetsPieter MestdaghPeter PipelersTom TaghonDavid Camacho TrujilloDavid AvranGert Van PeerNadine Van RoyOlivier Thas et al.

2010

KLHL12-mediated ubiquitination of the dopamine D4 receptor does not target the receptor for degradation

Pieter RondouKamila SkieterskaAnn PackeuBéatrice LintermansPeter VanhoenackerGeorges VauquelinGuy HaegemanKathleen Van Craenenbroeck

A1 Journal Article in CELLULAR SIGNALLING

Resistance of the dopamine D4 receptor to agonist-induced internalization and degradation

Anneleen SpoorenPieter RondouKatarzyna DebowskaBéatrice LintermansLinda VermeulenBart SamynKamila SkieterskaGriet DebyserBart DevreesePeter Vanhoenacker et al.

A1 Journal Article in CELLULAR SIGNALLING

The dopamine D4 receptor: biochemical and signalling properties

Pieter RondouGuy HaegemanKathleen Van Craenenbroeck

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

2009

The role of KLHL12 in the signalling and the regulation of the dopamine D4 receptor

Pieter RondouGuy Haegeman

2008

BTB protein KLHL12 targets the dopamine D4 receptor for ubiquitination by a Cul3-based E3 ligase

Pieter RondouGuy HaegemanPeter VanhoenackerKathleen Van Craenenbroeck

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY