Research Explorer

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Researcher

Pieter-Jan De Sutter

Publications & Research Data

Awards & Distinctions

22 Results

2026

Developing tailored dosing recommendations for ciprofloxacin in critically ill children using a population approach based on total and unbound concentrations

Pieter-Jan De SutterEvelyn DhontDaphne VensPeter De PaepeJef WillemsPetra SchelstraeteJan Van BocxlaerAn VermeulenPieter De Cock

A1 Journal Article in CLINICAL MICROBIOLOGY AND INFECTION

2025

A framework for interdisciplinary environmental risk assessments of antibiotics : from patient to the environment

Qiyun ZhangJéssica AmorimPieter-Jan De SutterMorten SukKlaus KümmererTiina SikanenKarel De Schamphelaere

Comparative evaluation of approaches to convert microsampled capillary blood concentrations to plasma concentrations : paracetamol and metabolites as a case study

Laura BoffelPieter-Jan De SutterLuc De BaerdemaekerChristophe Stove

A1 Journal Article in AAPS JOURNAL

Developing evidence-based dosing recommendations for intravenous ciprofloxacin in critically ill children: a population pharmacokinetic study using total and unbound concentrations

Pieter-Jan De SutterEvelyn DhontDaphné VensPeter De PaepeJef WillemsPetra SchelstraeteJan Van BocxlaerAn VermeulenPieter De Cock

Dose-limiting toxicities of paclitaxel in breast cancer patients : studying interactions between pharmacokinetics, physical activity, and body composition : a protocol for an observational cohort study

Len De NysAnita Barzegar-FallahKatrien LanckmansStephane SteurbautDavid BeckwéeAmy de Haar-HollemanSteven ProvynElke GasthuysSofie Vande CasteelePieter-Jan De Sutter et al.

A1 Journal Article in CANCERS

Second-generation AURKA-targeting PROTACs : structural optimization toward in vivo degradation in neuroblastoma

Simon KrolsMuhammad RishfiFien MartensAnouk Van HauwermeirenEllen SandersPieter-Jan De SutterAn VermeulenKaat De WeverSarah-Lee BekaertM. Emmy M. Dolman et al.

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

Synergy of body composition, exercise oncology, and pharmacokinetics : a narrative review of personalizing paclitaxel treatment for breast cancer

Nele AdriaenssensStephanie C. M. WuytsStephane SteurbautPieter-Jan De SutterAn VermeulenAmy de Haar-HollemanDavid BeckwéeSteven ProvynSofie Vande CasteeleJinyu Zhou et al.

A1 Journal Article in CANCERS

2024

Application of pediatric-adapted modeling and simulation approaches

Pieter-Jan De SutterJonas LangeraertRobin MicheletAn Vermeulen

Bookchapter in Essentials of translational pediatric drug development : from past needs to future oportunities

Comparison of monoclonal antibody disposition predictions using different physiologically based pharmacokinetic modelling platforms

Pieter-Jan De SutterElke GasthuysAn Vermeulen

A1 Journal Article in JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Penetration of antibiotics into subcutaneous and intramuscular interstitial fluid : a meta-analysis of microdialysis studies in adults

Pieter-Jan De SutterEline HermansPieter De CockJan Van BocxlaerElke GasthuysAn Vermeulen

A1 Journal Article in CLINICAL PHARMACOKINETICS

Reliability of physiologically based pharmacokinetic models for the prediction of drug distribution and tissue concentrations

Pieter-Jan De SutterAn VermeulenJan Van Bocxlaer

2023

Comparison of monoclonal antibody disposition predictions between different PBPK platforms

Pieter-Jan De SutterElke GasthuysAn Vermeulen

High throughput determination of the biofilm prevention concentration for Pseudomonas aeruginosa biofilms using a synthetic cystic fibrosis sputum medium

Amber De BleeckereSara Van den BosschePieter-Jan De SutterTine BeirensAurélie CrabbéTom Coenye

A2 Journal Article in BIOFILM

PBPK modelling to predict local lung exposure of meropenem in people with cystic fibrosis

Pieter-Jan De SutterSofia ProostAn Vermeulen

Predicting volume of distribution in neonates : performance of physiologically based pharmacokinetic modelling

Pieter-Jan De SutterPhebe RossignolLien BreënsElke GasthuysAn Vermeulen

A1 Journal Article in PHARMACEUTICS

Predictive performance of physiologically based pharmacokinetic modelling of beta-lactam antibiotic concentrations in adipose, bone and muscle tissues

Pieter-Jan De SutterPieter De CockTN JohnsonH MustherElke GasthuysAn Vermeulen

A1 Journal Article in DRUG METABOLISM AND DISPOSITION

2022

Accuracy of PBPK-predicted tissue concentrations : a case study of beta-lactam antibiotics in fat, bone and muscle

Pieter-Jan De SutterPieter De CockTrevor N JohnsonHelen MustherElke GasthuysAn Vermeulen

Altered intravenous drug disposition in people living with cystic fibrosis : a meta‐analysis integrating top‐down and bottom‐up data

Pieter-Jan De SutterMaxime Van HaeverbekeEva Van BraeckelStephanie Van BiervlietJan Van BocxlaerAn VermeulenElke Gasthuys

A1 Journal Article in CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY

Comment on : 'Penetration of antibacterial agents into pulmonary epithelial lining fluid : an update'

Pieter-Jan De SutterJan De WaeleAn Vermeulen

A1 Journal Article in CLINICAL PHARMACOKINETICS

High throughput analytical report writing in R : a case study of validating an LC-MS method for the quantification of amoxicillin in human plasma

Pieter-Jan De SutterElke GasthuysAn VermeulenJan Van Bocxlaer

Physiologically based pharmacokinetic models for the prediction of beta-lactam antibiotic concentrations in perfusion-limited tissues

Pieter-Jan De SutterPieter De CockElke GasthuysAn Vermeulen

2020

Pharmacokinetics in patients with cystic fibrosis : a systematic review of data published between 1999 and 2019

Pieter-Jan De SutterElke GasthuysEva Van BraeckelPetra SchelstraeteStephanie Van BiervlietJan Van BocxlaerAn Vermeulen

A1 Journal Article in CLINICAL PHARMACOKINETICS