Research Explorer

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Researcher

Pieter Depuydt

Awards & Distinctions

161 Results

2023

A breath of relief : navigating the resolution of unexplained respiratory failure

Thor HautekietEmiel De JaeghereNina CardinaelsYannick Vande WeygaerdeDieter StevensEric DeromPieter Depuydt

A complement atlas identifies interleukin-6-dependent alternative pathway dysregulation as a key druggable feature of COVID-19

Karel Van DammeLevi HosteJozefien DeclercqElisabeth De LeeuwBastiaan MaesLiesbet MartensRoos ColmanRobin BrowaeysCédric BosteelsStijn Verwaerde et al.

A1 Journal Article in SCIENCE TRANSLATIONAL MEDICINE

Ferroptosis and pyroptosis signatures in critical COVID-19 patients

Cédric PelemanSamya Van CoillieSymen LigthartSze Men ChoiJan De WaelePieter DepuydtDominique BenoitHannah SchaubroeckSven M. FrancqueKarolien Dams et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

In-hospital antibiotic use for severe chronic obstructive pulmonary disease exacerbations : a retrospective observational study

Anna VanoverscheldeChloë Van HoeyFranky BuyleNadia Den BlauwenPieter DepuydtEva Van BraeckelLies Lahousse

A1 Journal Article in BMC PULMONARY MEDICINE

Pathogen-based target attainment of optimized continuous infusion dosing regimens of piperacillin-tazobactam and meropenem in surgical ICU patients : a prospective single center observational study

Thomas De CorteJarne VerhaegheSofie DhaeseSarah Van VoorenJerina BoelensAlain VerstraeteVeronique StoveFemke OngenaeLiesbet De BusPieter Depuydt et al.

A1 Journal Article in ANNALS OF INTENSIVE CARE

Selective digestive decontamination-Pro

Jan De WaeleIsabel Leroux-RoelsPieter Depuydt

Editorial material

Tight blood-glucose control without early parenteral nutrition in the ICU

J. GunstY. DebaveyeF. GuizaJ. DuboisA. De BruynD. DauweE. De TroyM. P. CasaerG. De VliegerR. Haghedooren et al.

A1 Journal Article in NEW ENGLAND JOURNAL OF MEDICINE

Video-assisted thoracic surgery in critically ill COVID-19 patients on venovenous extracorporeal membrane oxygenation

Bert ZwaenepoelKorneel VandewieleHarlinde PeperstraeteFREDERIC DE RYCKCaroline VanpeteghemTHOMAS MALFAITINGRID HERCKWim VandenbergheLien Van LaethemLuc Defreyne et al.

A1 Journal Article in PERFUSION

2022

Adult essential extracorporeal membrane oxygenation (ECMO) skills for use in an e-learning program for ICU physicians, nurses and perfusionists : a consensus by a modified Delphi questionnaire

Harlinde PeperstraeteAnnelien SteenhoutFilip De SomerPieter DepuydtEric HosteIsabelle Van Herzeele

A1 Journal Article in BMC MEDICAL EDUCATION

Antimicrobial prescription in severe COVID-19 and CAP : a matched case-control study

Jan FierensLiesbet De BusKirsten ColpaertJerina BoelensBram GadeyneJohan DecruyenaereEva Van BraeckelPieter Depuydt

A1 Journal Article in ACTA CLINICA BELGICA

Case report : hemorrhagic fever with renal syndrome presenting as hemophagocytic lymphohistiocytosis

Maarten De SmetSimon BogaertAlexander SchauwvliegheAmélie DendoovenPieter DepuydtPatrick Druwé

A1 Journal Article in FRONTIERS IN MEDICINE

Effect of antiplatelet therapy on survival and organ support-free days in critically ill patients with COVID-19 : a randomized clinical trial

Charlotte A. BradburyPatrick R. LawlerSimon J. StanworthBryan J. McVerryZoe McQuiltenAlisa M. HigginsPaul R. MounceyFarah Al-BeidhKathryn M. RowanLindsay R. Berry et al.

A1 Journal Article in JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Efficacy and safety of the investigational complement C5 inhibitor zilucoplan in patients hospitalized with COVID-19 : an open-label randomized controlled trial

Elisabeth De LeeuwKarel Van DammeJozefien DeclercqCédric BosteelsBastiaan MaesSimon TavernierLaurent DetalleTrevor SmartSophie GlattNincy Debeuf et al.

A1 Journal Article in RESPIRATORY RESEARCH

Foxglove poisoning : diagnostic and therapeutic differences with medicinal digitalis glycosides overdose

Koen MaesPieter DepuydtJoris VermassenPeter De PaepeWalter BuylaertCathelijne Lyphout

A1 Journal Article in ACTA CLINICA BELGICA

Healthcare-associated infections in adult intensive care unit patients : changes in epidemiology, diagnosis, prevention and contributions of new technologies

Stijn BlotEtienne RuppéStephan HarbarthKarim AsehnouneGaryphalia PoulakouCharles-Edouard LuytJordi RelloMichael KlompasPieter DepuydtChristian Eckmann et al.

A1 Journal Article in INTENSIVE AND CRITICAL CARE NURSING

Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment

Cédric BosteelsKarel Van DammeElisabeth De LeeuwJozefien DeclercqBastiaan MaesVictor BosteelsLevi HosteLeslie NaesensNincy DebeufJulie Deckers et al.

A1 Journal Article in CELL REPORTS MEDICINE

Microbial diversity and antimicrobial susceptibility in endotracheal tube biofilms recovered from mechanically ventilated COVID-19 patients

Frits van CharanteAnneleen WiemePetra RigoleEvelien De CanckLisa OstynLucia GrassiDieter DeforceAurélie CrabbéPeter VandammeMarie Joossens et al.

A2 Journal Article in BIOFILM

Prospective longitudinal evaluation of hospitalised COVID-19 survivors 3 and 12 months after discharge

Natalie LorentYannick Vande WeygaerdeEveline ClaeysIpek Guler Caamano FajardoNicolas De VosWalter De WeverBihiyga SalhiIwein GyselinckCédric BosteelsBart Lambrecht et al.

A1 Journal Article in ERJ OPEN RESEARCH

2021

Adult-onset congenital central hypoventilation syndrome due to PHOX2B mutation

Antoon MeylemansPieter DepuydtElfride De BaereKatrien HertegonneEric DeromBart DermautDimitri Hemelsoet

A1 Journal Article in ACTA NEUROLOGICA BELGICA

Attributable mortality of ventilator-associated pneumonia : replicating findings, revisiting methods

Johan SteenStijn VansteelandtLiesbet De BusPieter DepuydtBram GadeyneDominique BenoitJohan Decruyenaere

A1 Journal Article in ANNALS OF THE AMERICAN THORACIC SOCIETY

Characteristics of Sepsis-2 septic shock patients failing to satisfy the Sepsis-3 septic shock definition : an analysis of real-time collected data

Joris VermassenJohan DecruyenaereLiesbet De BusPieter DepuydtKirsten Colpaert

A1 Journal Article in ANNALS OF INTENSIVE CARE

Conceptions of the pathophysiology of happy hypoxemia in COVID-19

Sebastiaan DhontEric DeromEva Van BraeckelPieter DepuydtBart Lambrecht

A1 Journal Article in RESPIRATORY RESEARCH

Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID) : a factorial, randomised, controlled trial

Jozefien DeclercqKarel Van DammeElisabeth De LeeuwBastiaan MaesCédric BosteelsSimon TavernierStefanie De BuyserRoos ColmanMaya HitesGil Verschelden et al.

A1 Journal Article in LANCET RESPIRATORY MEDICINE

Optimizing the use of antibiotic agents in the pediatric intensive care unit : a narrative review

Jef WillemsEline HermansPetra SchelstraetePieter DepuydtPieter De Cock

A1 Journal Article in PEDIATRIC DRUGS

Outcomes of ICU patients with and without perceptions of excessive care : a comparison between cancer and non-cancer patients

Dominique BenoitEsther N. van der ZeeMichael DarmonAn K. L. ReynersVictoria MetaxaDjamel MokartAlexander WilmerPieter DepuydtAndreas HvarfnerKaterina Rusinova et al.

A1 Journal Article in ANNALS OF INTENSIVE CARE

Pharmacokinetics and target attainment of intravenous posaconazole in critically ill patients during extracorporeal membrane oxygenation

R Van DaeleRJ BrüggemannE DreesenPieter DepuydtB RijndersF CottonD FageM GijsenK Van ZwamY Debaveye et al.

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Posaconazole for prevention of invasive pulmonary aspergillosis in critically ill influenza patients (POSA-FLU) : a randomised, open-label, proof-of-concept trial

Lore VanderbekeNico A. F. JanssenDennis C. J. J. BergmansMarc BourgeoisJochem B. BuilYves DebaveyePieter DepuydtSimon FeysGreet HermansOscar Hoiting et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Taskforce report on the diagnosis and clinical management of COVID-19 associated pulmonary aspergillosis

Paul E. VerweijRoger J. M. BrüggemannElie AzoulayMatteo BassettiStijn BlotJochem B. BuilThierry CalandraTom ChillerCornelius J. ClancyOliver A. Cornely et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Triage policy of severe Covid-19 patients : what to do now?

Pieter DepuydtB Guidet

A1 Journal Article in ANNALS OF INTENSIVE CARE

2020

Antimicrobial de-escalation in critically ill patients : a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill Patients Study Group (ESGCIP)

Alexis TabahMatteo BassettiMarin H KollefJean-Ralph ZaharJosé-Artur PaivaJean-Francois TimsitJason A RobertsJeroen SchoutenHelen GiamarellouJordi Rello et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure : the DIANA study

Liesbet De BusPieter DepuydtJohan SteenSofie DhaeseKen De SmetAlexis TabahMurat AkovaMenino Osbert CottaGennaro De PascaleGeorge Dimopoulos et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Automated screening of natural language in electronic health records for the diagnosis septic shock is feasible and outperforms an approach based on explicit administrative codes

Joris VermassenKirsten ColpaertLiesbet De BusPieter DepuydtJohan Decruyenaere

A1 Journal Article in JOURNAL OF CRITICAL CARE

Case report : convalescent plasma, a targeted therapy for patients with CVID and severe COVID-19

Karel Van DammeSimon TavernierNele Van RoyElisabeth De LeeuwJozefien DeclercqCédric BosteelsBastiaan MaesMarieke De BruyneDelfien BogaertVictor Bosteels et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Efficacy, immunogenicity, and safety of IC43 recombinant Pseudomonas aeruginosa vaccine in mechanically ventilated intensive care patients : a randomized clinical trial

Christopher AdlbrechtRaphael WurmPieter DepuydtHerbert SpapenJose A. LorenteThomas StaudingerJacques CreteurChristian ZaunerAndreas Meier-HellmannPhilipp Eller et al.

A1 Journal Article in CRITICAL CARE

Epidemiology of Pneumocystis jirovecii pneumonia and (non-)use of prophylaxis

Albert DunbarAlexander SchauwvliegheSheruna AlgoeJaap J. van HellemondMarijke ReyndersStefaan VandecasteeleJerina BoelensPieter DepuydtBart Rijnders

A1 Journal Article in FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY

Guideline on the prudent prescription of antibiotics in the dental office

Roos LeroyJolyce BourgeoisLeen VerleyeDominique DeclerckPieter DepuydtAnouk ElootJoana CarvalhoWim TeughelsRita CauwelsJulian Leprince et al.

Haemoptysis as the first presentation of COVID-19 : a case report

Elise PeysDieter StevensYannick Vande WeygaerdeThomas MalfaitLaurens HermieP RogiersPieter DepuydtEva Van Braeckel

A1 Journal Article in BMC PULMONARY MEDICINE

Outcome after surgical procedures in adult home ventilated patients at Ghent University Hospital : a registry study

Lauren HeymanEric DeromPieter DepuydtLuc De BaerdemaekerGuy Joos

Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition : an expert opinion

Paul E. VerweijBart J. A. RijndersRoger J. M. BrüggemannElie AzoulayMatteo BassettiStijn BlotThierry CalandraCornelius J. ClancyOliver A. CornelyTom Chiller et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

The pathophysiology of 'happy' hypoxemia in COVID-19

Sebastiaan DhontEric DeromEva Van BraeckelPieter DepuydtBart Lambrecht

A1 Journal Article in RESPIRATORY RESEARCH

2019

A practical approach to clinical antibiotic stewardship in the ICU patient with severe infection

Jan FierensPieter DepuydtJan De Waele

A1 Journal Article in SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Benign gastrobronchial fistula following oesophagectomy in a patient presenting with respiratory failure

Kasper FavereKlaas VanderbiestJan BresseleersPieter Depuydt

A2 Journal Article in BMJ CASE REPORTS

Changes in critically ill cancer patients’ short-term outcome over the last decades : results of systematic review with meta-analysis on individual data

Michaël DarmonAurélie BourmaudQuentin GeorgesMarcio SoaresKyeongman JeonSandra OeyenChin Kook RheePascale GruberMarlies OstermannQuentin A Hill et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Continuous infusion of beta-lactam antibiotics in the critically ill : unresolved pharmacokinetic and pharmacodynamic issues

Sofie DhaeseJan De WaeleVeronique StovePieter Depuydt

Meningitis in a patient with neutropenia due to Rothia mucilaginosa : a case report

Maxim ClauwaertPatrick DruwéPieter Depuydt

A2 Journal Article in JOURNAL OF MEDICAL CASE REPORTS

Optimal and responsible use of antibiotics

Pieter DepuydtJan De Waele

A1 Journal Article in CURRENT OPINION IN CRITICAL CARE

Outcomes of patients presenting with mild acute respiratory distress syndrome : insights from the LUNG SAFE study

Tài PhamAry Serpa NetoPaolo PelosiJohn Gerard LaffeyCandelaria De HaroJose Angel LorenteGiacomo BellaniEddy FanLaurent Jean BrochardAntonio Pesenti et al.

A1 Journal Article in ANESTHESIOLOGY

Saturable elimination of piperacillin in critically ill patients : implications for continuous infusion

Sofie DhaesePieter ColinHelena WillemsA HeffernanBram GadeyneSarah Van VoorenPieter DepuydtEric HosteVeronique StoveAlain Verstraete et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

What happens after ICU discharge? : a within-hospital seamless care analysis of antimicrobial therapy

Barbara ClausJan De WaeleJolien LanguiPieter Depuydt

2018

A complete and multifaceted overview of antibiotic use and infection diagnosis in the intensive care unit : results from a prospective four-year registration

Liesbet De BusBram GadeyneJohan SteenJerina BoelensGeert ClaeysDominique BenoitJan De WaeleJohan DecruyenaerePieter Depuydt

A1 Journal Article in CRITICAL CARE

Anti-MDA5 positive dermatomyositis complicated with rapidly progressive interstitial lung disease : a case report

Eva De BackerFélix GremonprezGuy BrussellePieter DepuydtJo Van DorpeCarole Van HaverbekePieter GoeminneEric Derom

A1 Journal Article in ACTA CLINICA BELGICA

Beat around the bush for VA-LRTI

Ignacio Martin-LoechesPieter DepuydtMichael S Niederman

Editorial material

Decontamination strategies and bloodstream infections with antibiotic-resistant microorganisms in ventilated patients : a randomized clinical trial

Bastiaan H WittekampNienke L PlantingaBen S CooperJoaquin Lopez-ContrerasPere CollJordi ManceboMatt P WiseMatt PG MorganPieter DepuydtJerina Boelens et al.

A1 Journal Article in JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Emergence of antimicrobial resistance to piperacillin/tazobactam or meropenem in the ICU : intermittent versus continuous infusion : a retrospective cohort study

Sofie DhaeseMagalie De KezelMaxime CallantJerina BoelensLiesbet De BusPieter DepuydtJan De Waele

A1 Journal Article in JOURNAL OF CRITICAL CARE

Impact of AST meetings on antimicrobial therapy decisions in the ICU

Sofie DhaeseLiesbet De BusJerina BoelensLiselotte CoorevitsBruno VerhasseltPieter DepuydtJan De Waele

Influence of neutropenia on mortality of critically ill cancer patients : results of a meta-analysis on individual data

Quentin GeorgesElie AzoulayDjamel MokartMarcio SoaresKyeongman JeonSandra OeyenChin Kook RheePascale GruberMarlies OstermannQuentin A Hill et al.

A1 Journal Article in CRITICAL CARE

Invasive aspergillosis in patients admitted to the intensive care unit with severe influenza : a retrospective cohort study

Alexander FAD SchauwvliegheBart JA RijndersNele PhilipsRosanne VerwijsLore VanderbekeCarla Van TienenKatrien LagrouPaul E VerweijFrank L Van de VeerdonkDiederik Gommers et al.

A1 Journal Article in LANCET RESPIRATORY MEDICINE

Use of a computer-assisted registration program to investigate antibiotic prescription and antibiotic resistance in the intensive care unit

Liesbet De BusPieter DepuydtJohan Decruyenaere

2017

Low flow extracorporeal CO2 removal in ARDS patients : a prospective short-term crossover pilot study

Harlinde PeperstraeteSunny ElootPieter DepuydtFilip De SomerCARL ROOSENSEric Hoste

A1 Journal Article in BMC ANESTHESIOLOGY

P. aeruginosa colonization at ICU admission as a risk factor for developing P. aeruginosa ICU pneumonia

Fleur P PalingMartin WolkewitzPieter DepuydtLiesbet De BusFrangiscos SifakisMarc JM BontenJan AJW Kluytmans

A1 Journal Article in ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL

Staphylococcus aureus colonization at ICU admission as a risk factor for developing S. aureus ICU pneumonia

FP PalingM WolkewitzLGM BodePMC Klein KlouwenbergDSY OngPieter DepuydtLiesbet De BusF SifakisMJM BontenJAJW Kluytmans

A1 Journal Article in CLINICAL MICROBIOLOGY AND INFECTION

The Intensive Care Medicine research agenda on critically ill oncology and hematology patients

Elie AzoulayPeter SchellongowskiMichael DarmonPhilippe R BauerDominique BenoitPieter DepuydtJigeeshu V DivatiaVirginie LemialeMaarten van VlietAnne-Pascale Meert et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

2016

Antibiotic stewardship : do not rely on de-escalation alone

Liesbet De BusPieter Depuydt

A1 Journal Article in INTENSIVE CARE MEDICINE

Disulfiram inhibition of cyanide formation after acetonitrile poisoning

Peter De PaepePieter ColinPieter DepuydtAn-Sofie DecaveleJulie De SmetKoen BousseryChristophe StoveDominique BenoitAlain VerstraeteJan Van Bocxlaer et al.

A1 Journal Article in CLINICAL TOXICOLOGY

Impact of de-escalation of beta-lactam antibiotics on the emergence of antibiotic resistance in ICU patients : a retrospective observational study

Liesbet De BusWOUTER DENYSJULIE CATTEEUWBram GadeyneKarel VermeulenJerina BoelensGeert ClaeysJan De WaeleJohan DecruyenaerePieter Depuydt

A1 Journal Article in INTENSIVE CARE MEDICINE

Long-term outcome and health-related quality of life in difficult-to-wean patients with and without ventilator dependency at ICU discharge : a retrospective cohort study

Pieter DepuydtSandra OeyenS De SmetS De RaedtDominique BenoitJohan DecruyenaereEric Derom

A1 Journal Article in BMC PULMONARY MEDICINE

Noninvasive mechanical ventilation in critically ill patients with hematological malignancy : flow chart, evidence, and key practical recommendations

Bookchapter in Noninvasive mechanical ventilation : theory, equipment, and clinical applications

Oral mucosal adverse events with chlorhexidine 2 % mouthwash in ICU

Nienke L PlantingaBastiaan HJ WittekampKris LeleuPieter DepuydtAnne-Marie Van den AbeeleChristian Brun-BuissonMarc JM Bonten

A1 Journal Article in INTENSIVE CARE MEDICINE

Prone position acute respiratory distress syndrome patients : less prone to ventilator associated pneumonia?

H DupontPieter DepuydtF Abroug

Editorial material

Reducing antibiotic use in the ICU : a time-based approach to rational antimicrobial use

Pieter DepuydtLiesbet De BusJan De Waele

Bookchapter in Annual update in intensive care and emergency medicine 2016

2015

Farmacotherapeutische actualiteit

Pauline De BruynePieter DepuydtLucas Van BortelThierry Christiaens

Editorial material

Farmacotherapeutische actualiteit

Robert Vander SticheleLucas Van BortelPieter DepuydtThierry Christiaens

Editorial material

The ten 'diseases' that are not true diseases

Pieter DepuydtJohn P KressJorge IF Salluh

Editorial material

2014

Development of antibiotic treatment algorithms based on local ecology and respiratory surveillance cultures to restrict the use of broad-spectrum antimicrobial drugs in the treatment of hospital-acquired pneumonia in the intensive care unit : a retrospective analysis

Liesbet De BusLIES SAERENSBram GadeyneJerina BoelensGeert ClaeysJan De WaeleDominique BenoitJohan DecruyenaerePieter Depuydt

A1 Journal Article in CRITICAL CARE

Disulfiram inhibition of cyanide formation after acetonitrile poisoning

Peter De PaepePieter ColinPieter DepuydtAn-Sofie DecaveleJulie De SmetKoen BousseryChristophe StoveDOMINIQUE BENOITAlain VerstraeteJan Van Bocxlaer et al.

Dual disseminated infection with Nocardia farcinica and Mucor in a patient with systemic lupus erythematosus : a case report

FREDERIK DE CLERCKFLORENCE VAN RYCKEGHEMPieter DepuydtDominique BenoitPATRICK DRUWEArnika HugelGeert ClaeysPiet CoolsJohan Decruyenaere

A2 Journal Article in JOURNAL OF MEDICAL CASE REPORTS

Extended versus bolus infusion of meropenem and piperacillin: a pharmacokinetic analysis

Jan De WaeleMieke CarlierEric HostePieter DepuydtJohan DecruyenaereSteven C WallisJeffrey LipmanJason A Roberts

A1 Journal Article in MINERVA ANESTESIOLOGICA

Noninvasive mechanical ventilation in high-risk pulmonary infections: a clinical review

Antonio M EsquinasS Egbert PravinkumarRaffaele ScalaPeter GayArie SorokskyChristophe GiraultFang HanDavid S HuiPeter J PapadakosNicolino Ambrosino et al.

A2 Journal Article in EUROPEAN RESPIRATORY REVIEW

Protease production by Staphylococcus epidermidis and its effect on Staphylococcus aureus biofilms

Ilse VandecandelaerePieter DepuydtHans NelisTom Coenye

A1 Journal Article in PATHOGENS AND DISEASE

Therapeutic drug monitoring-based dose optimisation of piperacillin and meropenem: a randomised controlled trial

Jan De WaeleSofie CarretteMieke CarlierVeronique StoveJerina BoelensGeert ClaeysIsabel Leroux-RoelsEric HostePieter DepuydtJohan Decruyenaere et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Validity analysis of a unique infection surveillance system in the intensive care unit by analysis of a data warehouse built through a workflow-integrated software application

Liesbet De BusGUNTER DIETBram GadeyneIsabel Leroux-RoelsGeert ClaeysKristof SteurbautDominique BenoitFilip De TurckJohan DecruyenaerePieter Depuydt

A1 Journal Article in JOURNAL OF HOSPITAL INFECTION

2013

A survey of beta-lactam antibiotics and vancomycin dosing strategies in intensive care units and general wards in Belgian hospitals.

Franky BuyleJohan DecruyenaereJan De WaelePaul M TulkensThijs Van AudenrodePieter DepuydtGeert ClaeysHugo RobaysDirk Vogelaers

A1 Journal Article in EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Diagnostic potential of open lung biopsy in mechanically ventilated patients with diffuse pulmonary infiltrates of unclear aetiology

Pieter DepuydtCharlotte DaezeDominique BenoitMarleen PraetFrank VermassenJohan Decruyenaere

A1 Journal Article in ANAESTHESIA AND INTENSIVE CARE

Factors associated with inadequate early vancomycin levels in critically ill patients treated with continuous infusion

Jan De WaeleI DanneelsPieter DepuydtJohan DecruyenaereM BourgeoisEric Hoste

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Long-term outcomes and quality of life in critically ill patients with hematological or solid malignancies: a single center study

Sandra OeyenDominique BenoitLieven AnnemansPieter DepuydtSimon Van BelleRoberto TroisiLucien NoensPiet PattynJohan Decruyenaere

A1 Journal Article in INTENSIVE CARE MEDICINE

Meropenem and piperacillin/tazobactam prescribing in critically ill patients : does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended infusions are used?

Mieke CarlierSofie CarretteJason A RobertsVeronique StoveAlain VerstraeteEric HosteJohan DecruyenaerePieter DepuydtJeffrey LipmanSteven C Wallis et al.

A1 Journal Article in CRITICAL CARE

Microbial etiology and antimicrobial resistance in healthcare-associated versus community-acquired and hospital-acquired bloodstream infection in a tertiary care hospital

Liesbet De BusGwen CoessensJerina BoelensGeert ClaeysJohan DecruyenaerePieter Depuydt

A1 Journal Article in DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

The presence of antibiotic-resistant nosocomial pathogens in endotracheal tube biofilms and corresponding surveillance cultures

Ilse VandecandelaereNele MatthijsHans NelisPieter DepuydtTom Coenye

A1 Journal Article in PATHOGENS AND DISEASE

2012

Assessment of microbial diversity in biofilms recovered from endotracheal tubes using culture dependent and independent approaches

Ilse VandecandelaereNele MatthijsFilip Van NieuwerburghDieter DeforcePETER VOSTERSLiesbet De BusHans NelisPieter DepuydtTom Coenye

A1 Journal Article in PLOS ONE

COSARA: integrated service platform for infection surveillance and antibiotic management in the ICU

Kristof SteurbautKirsten ColpaertBram GadeynePieter DepuydtPETER VOSTERSCHRISTIAN DANNEELSDominique BenoitJohan DecruyenaereFilip De Turck

A1 Journal Article in JOURNAL OF MEDICAL SYSTEMS

Characteristics and determinants of outcome of hospital-acquired bloodstream infections in intensive care units: the EUROBACT international cohort study

Alexis TabahDespoina KoulentiKevin LauplandBenoit MissetJordi VallesFrederico Bruzzi de CarvalhoJosé Artur PaivaNahit ÇakarXiaochun MaPhilippe Eggimann et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Early recognition of malignant lactic acidosis in clinical practice: report on 6 patients with haematological malignancies

EA De RaesDominique BenoitPieter DepuydtFritz OffnerJ NolletANNA VANTILBORGHEVA STEELLucien NoensJohan Decruyenaere

A1 Journal Article in ACTA CLINICA BELGICA

Fatal acute pulmonary injury associated with everolimus

Pieter DepuydtJOKE NOLLETDominique BenoitMarleen PraetFRANK CAES

A2 Journal Article in ANNALS OF PHARMACOTHERAPY

TDM based dose optimization of piperacillin and meropenem: a randomized controlled trial

Jan De WaeleSofie CarretteMieke CarlierVeronique StoveEric HostePieter DepuydtJohan DecruyenaereAlain Verstraete

2011

Attributable mortality of ventilator associated pneumonia: a reappraisal using causal analysis

Maarten BekaertJean-Francois TimsitStijn VansteelandtPieter DepuydtAurélien VésinMaité Garrouste-OrgeasJohan DecruyenaereChristoph Clec'hElie AzoulayDominique Benoit

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Nursing home residence is the main risk factor for increased mortality in healthcare-associated pneumonia

Pieter DepuydtBarbara PutmanDOMINIQUE BENOITWalter BuylaertPeter De Paepe

A1 Journal Article in JOURNAL OF HOSPITAL INFECTION

Open lung biopsy in patients with acute respiratory failure and bilateral pulmonary infiltrates

Charlotte DaezeJ NolletDominique BenoitFlor VermassenMarleen PraetJohan DecruyenaerePieter Depuydt

Outcome in critically ill patients with allogeneic BM or peripheral haematopoietic SCT : a single-centre experience

Pieter DepuydtTessa KerreLucien NoensJOKE NOLLETFritz OffnerJohan DecruyenaereDominique Benoit

A1 Journal Article in BONE MARROW TRANSPLANTATION

Perceptions of appropriateness of care among European and Israeli intensive care unit nurses and physicians

Ruth PiersElie AzoulayBara RicouFreda DeKeyser GanzJohan DecruyenaereAdeline MaxAndrej MichalsenPaulo Azevedo MaiaRadoslaw OwczukFrancesca Rubulotta et al.

A1 Journal Article in JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Prevalence of perceptions of inappropriate care among intensive care unit healthcare providers and reasons why disproportional care is continued : the APPROPRICUS study

Ruth PiersElie AzoulayDominique BenoitBara RicouFreda DeKeyserJohan DecruyenaereAdeline MaxAndrej MichalsenPieter DepuydtRadoslaw Owczuk et al.

2010

Aspiration pneumonia : an underestimated cause of severe respiratory failure in patients with haematological malignancies and severe oral mucositis?

Nicolaas De NeveDominique BenoitPieter DepuydtFritz OffnerJOKE NOLLETLucien NoensJohan Decruyenaere

A1 Journal Article in ACTA CLINICA BELGICA

De-escalation after empirical meropenem treatment in the intensive care unit: fiction or reality?

Jan De WaeleMariska RavytsPieter DepuydtStijn BlotJohan DecruyenaereDirk Vogelaers

A1 Journal Article in JOURNAL OF CRITICAL CARE

Impact of organ dysfunction on mortality in ICU patients with hematologic malignancies

Dominique VandijckPieter DepuydtFritz OffnerJOKE NOLLETRenaat PelemanEVA STEELLucien NoensJohan DecruyenaereDominique Benoit

A1 Journal Article in INTENSIVE CARE MEDICINE

Mechanical ventilation in cancer patients : clinical characteristics and outcomes

Márcio SoaresPieter DepuydtJorge IF Salluh

A1 Journal Article in CRITICAL CARE CLINICS

Non-invasive ventilation in patients with hematological malignancies: the saga continues, but where is the finale?

Dominique BenoitPieter Depuydt

Editorial material

Preliminary results from the APPROPRICUS study (APPROPRIATENESS of CARE in the ICUs)

Ruth PiersElie AzoulayBara RicouFreda De KeyserJohan DecruyenaereAdeline MaxAndrej MichalsenPieter DepuydtRadoslaw OwczukPaulo Azevedo Maia et al.

Severe drug-induced liver injury associated with prolonged use of Linezolid

Liesbet De BusPieter DepuydtLouis LibbrechtLinos VandekerckhoveJOKE NOLLETDominique BenoitDirk VogelaersHans Van Vlierberghe

A2 Journal Article in JOURNAL OF MEDICAL TOXICOLOGY

The impact of the initial ventilatory strategy on survival in hematological patients with acute hypoxemic respiratory failure

Pieter DepuydtDominique BenoitCARL ROOSENSFritz OffnerLucien NoensJohan Decruyenaere

A1 Journal Article in JOURNAL OF CRITICAL CARE

Use of web services for computerized medical decision support, including infection control and antibiotic management, in the intensive care unit

Kristof SteurbautSofie Van HoeckeKirsten ColpaertKristof LamontKristof TaveirnePieter DepuydtDominique BenoitJohan DecruyenaereFilip De Turck

A1 Journal Article in JOURNAL OF TELEMEDICINE AND TELECARE

2009

ADMINISTRATION OF VANCOMYCIN USING A STANDARDIZED PROTOCOL: DO WE ACHIEVE THERAPEUTIC SERUM CONCENTRATION IN THE INITIAL PHASE IN CRITICALLY ILL PATIENTS?

I. DanneelsJan De WaelePieter DepuydtJohan DecruyenaereEric Hoste

Design of software services for computer-based infection control and antibiotic management in the intensive care unit

Kristof SteurbautSofie Van HoeckeKristof TaveirneKristof LamontFilip De TurckKirsten ColpaertPieter DepuydtDominique BenoitCHRISTIAN DANNEELSJohan Decruyenaere

EVOLUTION IN COAGULATION PARAMETERS OVER THE FIRST 3 DAYS OF ICU ADMISSION IN SEPTIC SHOCK PATIENTS: IMPACT ON 30 DAY MORTALITY

Maarten BekaertJOKE NOLLETPieter DepuydtJohan DecruyenaereJan De WaeleCHRISTIAN DANNEELSStijn VansteelandtDominique Benoit

Preventie van nosocomiale pneumonie: antibioticastrategieën bij mechanisch geventileerde patiënten

Dominique VandijckPieter DepuydtStijn BlotJohan DecruyenaereDirk Vogelaers

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Trombotische microangiopathie als eerste teken van gemetastaseerd borstcarcinoom

Wouter De CorteSylvie RotteyPieter DepuydtJOKE NOLLETJ. PhillipéDominique Benoit

A2 Journal Article in Tijdschrift voor Geneeskunde

2008

Bacteremia in patients with febrile neutropenia following chemotherapy

Dominique VandijckPieter DepuydtStijn BlotJohan Decruyenaere

A1 Journal Article in INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Daily cost of antimicrobial therapy in patients with Intensive Care Unit-acquired, laboratory-confirmed bloodstream infection

Dominique VandijckMieke DepaemelaereSonia LabeauPieter DepuydtLieven AnnemansFranky BuyleSandra OeyenKirsten ColpaertRenaat PelemanStijn Blot et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Determinants and impact of multidrug antibiotic resistance in pathogens causing ventilator-associated-pneumonia

Pieter DepuydtDominique VandijckMaarten BekaertJohan DecruyenaereStijn BlotDirk VogelaersDominique Benoit

A1 Journal Article in Critical Care

Impact of recent intravenous chemotherapy on outcome in severe sepsis and septic shock patients with hematological malignancies

Dominique VandijckDominique BenoitPieter DepuydtFritz OffnerStijn BlotAnna K Van TilborghJOKE NOLLETEVA STEELLucien NoensJohan Decruyenaere

A1 Journal Article in INTENSIVE CARE MEDICINE

Improving the adequacy of empirical beta-lactam therapy for Pseudomonas aeruginosa ventilator-associated pneumonia

Pieter DepuydtStijn BlotDOMINIQUE BENOITJohan Decruyenaere

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Maximizing rates of empiric appropriate antibiotic therapy with minimized use of broad-spectrum agents: are surveillance cultures the key?

Stijn BlotPieter DepuydtDirk Vogelaers

Editorial material

Polyurethane cuffed endotracheal tubes to prevent early postoperative pneumonia after cardiac surgery: A pilot study

Jan PoelaertPieter DepuydtAnnick De WolfStijn Van de VeldeINGRID HERCKStijn Blot

A1 Journal Article in JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Predictive value of surveillance cultures and subsequent bacteremia with extended-spectrum beta-lactamase-producing Enterobacteriaceae

Stijn BlotPieter DepuydtDominique VandijckKoenraad VandewoudeRenaat PelemanDirk Vogelaers

A1 Journal Article in CLINICAL INFECTIOUS DISEASES

Risk factors and outcome in ventilator-associated pneumonia

Pieter DepuydtDries MynyStijn Blot

Bookchapter in Year Book Respiratory Care Clinics and Applied Technologies

Support Vector machine versus logistic regression modeling for prediction of hospital mortality in critically ill patients with haematological malignancies

Thierry VerplanckeStijn Van LooyDominique BenoitStijn VansteelandtPieter DepuydtFilip De TurckJohan Decruyenaere

A1 Journal Article in BMC MEDICAL INFORMATICS AND DECISION MAKING

Systematic surveillance cultures as a tool to predict involvement of multidrug antibiotic resistant bacteria in ventilator-associated pneumonia

Pieter DepuydtDominique BenoitDirk VogelaersJohan DecruyenaereDominique VandijckGeert ClaeysGerda VerschraegenStijn Blot

A1 Journal Article in INTENSIVE CARE MEDICINE

Temocillin: a valid option for directed therapy in ICU patients?

D Njdekembo ShangoPieter DepuydtStijn BlotKirsten ColpaertEric HosteSandra OeyenCARL ROOSENSDirk VogelaersJohan DecruyenaereJan De Waele

2007

Antibiotic therapy for community-acquired pneumonia with septic shock: Follow the guidelines

Stijn BlotPieter Depuydt

Editorial material

Antibiotic therapy for ventilator-associated pneumonia: De-escalation in the real world

Pieter DepuydtStijn Blot

Editorial material

Bacteremia in patients with ventilator-associated pneumonia is associated with increased mortality: A study comparing bacteremic vs. nonbacteremic ventilator-associated pneumonia

K AGBAHTE DIAZE MUNOZT LISBOAF GOMEZPieter DepuydtStijn BlotJ RELLO

A1 Journal Article in CRITICAL CARE MEDICINE

Comment on: Impact of antibiotic resistance and of adequate empirical antibiotic treatment in the prognosis of patients with Escherichia coli bacteraemia

Stijn BlotDominique VandijckKoenraad VandewoudePieter DepuydtDirk VogelaersRenaat Peleman

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Community-acquired versus nosocomial Klebsiella pneumonia bacteremia: Clinical features, treatment outcomes, and clinical implication of antimicrobial resistance

Dominique VandijckJohan DecruyenaerePieter DepuydtStijn Blot

A1 Journal Article in JOURNAL OF KOREAN MEDICAL SCIENCE

Dynamics of C-reactive protein and white blood cell count in critically ill patients with nosocomial Gram positive vs. Gram negative bacteremia: a historical cohort study

Dominique VandijckEric HosteStijn BlotPieter DepuydtRenaat PelemanJohan Decruyenaere

A1 Journal Article in BMC INFECTIOUS DISEASES

Measuring the impact of multidrug resistance in nosocomial infection

Stijn BlotPieter DepuydtKoenraad VandewoudeDirk De Bacquer

A1 Journal Article in CURRENT OPINION IN INFECTIOUS DISEASES

Microbial surveillance in the intensive care unit

Stijn BlotPieter DepuydtKoenraad Vandewoude

Bookchapter in Infectious diseases in critical care

Multidrug resistant pathogens in bacterial infections acquired at the intensive care unit and the contribution of surveillance cultures to early appropriate antibiotic therapy

Pieter DepuydtJohan DecruyenaereStijn Blot

Nosocomiale pneumonie buiten het ziekenhuis: 'health-care associated pneumonia' en rusthuispneumonie

Pieter DepuydtDirk Vogelaers

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Tracheotomy: clinical review and guidelines

P DE LEYNL BEDERTM DELCROIXPieter DepuydtG LAUWERSY SOKOLOVA VAN MEERHAEGHEP VAN SCHIL

A1 Journal Article in EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

2006

Antimicrobial resistance in nosocomial bloodstream infection associated with pneumonia and the value of systematic surveillance cultures in an adult intensive care unit

Pieter DepuydtStijn BlotDOMINIQUE BENOITGeert ClaeysGerda VerschraegenKoenraad VandewoudeDirk VogelaersJohan DecruyenaereFrancis Colardyn

A1 Journal Article in CRITICAL CARE MEDICINE

Clinical relevance of Aspergillus isolation from respiratory tract samples in critically ill patients

Koenraad VandewoudeStijn BlotPieter DepuydtDOMINIQUE BENOITW TEMMERMANFrancis ColardynDirk Vogelaers

A1 Journal Article in CRITICAL CARE

Dynamics of C-reactive protein in critically ill patients with nosocomial gram-positive versus gram-negative bacteremia

Dominique VandijckEric HosteStijn BlotPieter DepuydtJohan DecruyenaereRenaat PelemanDirk Vogelaers

Effects of selection of control subjects in a case-control study on the outcome of catheter-related bloodstream infection - Reply to Rijnders

Stijn BlotPieter DepuydtKoenraad Vandewoude

A1 Journal Article in CLINICAL INFECTIOUS DISEASES

Nosocomial pneumonia: aetiology, diagnosis and treatment

Pieter DepuydtDries MynyStijn Blot

A1 Journal Article in CURRENT OPINION IN PULMONARY MEDICINE

Outcome in bacteremia associated with nosocomial pneumonia and the impact of pathogen prediction by tracheal surveillance cultures

Pieter DepuydtDOMINIQUE BENOITDirk VogelaersGeert ClaeysGerda VerschraegenKoenraad VandewoudeJohan DecruyenaereStijn Blot

A1 Journal Article in INTENSIVE CARE MEDICINE

Outcome in severely ill patients with hematological malignancies who received intravenous chemotherapy in the intensive care unit

DOMINIQUE BENOITPieter DepuydtKoenraad VandewoudeFritz OffnerTom BoterbergCHANTAL DE COCKLucien NoensAnne JanssensJohan Decruyenaere

A1 Journal Article in INTENSIVE CARE MEDICINE

Poly-urethane cuffed versus conventional endotracheal tube in the prevention of early postoperative pneumonia in cardiac surgery patients: a randomized trial

Stijn Van de VeldePieter DepuydtStijn BlotJan Poelaert

Value of poly-urethane cuffed endotracheal tube in the prevention of early post-operative pneumonia

Annick De WolfStijn BlotStijn Van de VeldePieter DepuydtJan Poelaert

2005

Antibiotic therapy and outcome in critically ill patients with pneumococcal bacteremia

Pieter DepuydtDOMINIQUE BENOITK VANDEWOUDFJohan Decruyenaere

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Clinical and economic outcomes in critically ill patients with nosocomial catheter-related bloodstream infections

Stijn BlotPieter DepuydtLieven AnnemansDOMINIQUE BENOITEric HosteJAN DE WAELEJohan DecruyenaereDirk VogelaersFrancis ColardynKoenraad Vandewoude

A1 Journal Article in CLINICAL INFECTIOUS DISEASES

Colonization status and appropriate antibiotic therapy for nosocomial bacteremia caused by antibiotic-resistant gram-negative bacteria in an intensive care unit

Stijn BlotPieter DepuydtDirk VogelaersJohan DecruyenaereJAN DE WAELEEric HosteRenaat PelemanGeert ClaeysGerda VerschraegenFrancis Colardyn et al.

A1 Journal Article in INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Documented and clinically suspected bacterial infection precipitating intensive care unit admission in patients with hematological malignancies: impact on outcome

DOMINIQUE BENOITPieter DepuydtRenaat PelemanFritz OffnerKoenraad VandewoudeDirk VogelaersStijn BlotLucien NoensFrancis ColardynJohan Decruyenaere

A1 Journal Article in INTENSIVE CARE MEDICINE

Influence of matching for exposure time on estimates of attributable mortality caused by nosocomial bacteremia in critically ill patients

Stijn BlotDirk De BacquerEric HostePieter DepuydtKoenraad VandewoudeJan De WaeleDOMINIQUE BENOITJOHAN DE SCHUIJMERFrancis ColardynDirk Vogelaers

A1 Journal Article in INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Outcome in critically ill medical patients treated with renal replacement therapy for acute renal failure: comparison between patients with and those without haematological malignancies

DOMINIQUE BENOITEric HostePieter DepuydtFritz OffnerNorbert LameireKoenraad VandewoudeAnnemieke DhondtLucien NoensJohan Decruyenaere

A1 Journal Article in NEPHROLOGY DIALYSIS TRANSPLANTATION

Ventilator-associated pneumonia in a tertiary care ICU: Analysis of risk factors for acquisition and mortality

DRIES MYNYPieter DepuydtFrancis ColardynStijn Blot

A1 Journal Article in ACTA CLINICA BELGICA

Would patients with more subtle signs of coagulopathy have benefited from treatment with activated protein C?

DOMINIQUE BENOITPieter DepuydtJAN DE WAELEEric HosteME COLPAERTVANESSA VAN HENDEJohan Decruyenaere

A1 Journal Article in CRITICAL CARE MEDICINE

2004

Artificial neural networks in predicting outcome of gastrointestinal haemorrhage

DOMINIQUE BENOITJohan DecruyenaerePieter DepuydtKIRSTEN COLPAERT

A1 Journal Article in LANCET

Bacterial infection

DOMINIQUE BENOITPieter DepuydtKoenraad Vandewoude

A1 Journal Article in CRITICAL CARE MEDICINE

Invasive aspergillosis in critically ill patients: Analysis of risk factors for acquisition and mortality

Koenraad VandewoudeStijn BlotDOMINIQUE BENOITPieter DepuydtDirk VogelaersFrancis Colardyn

A1 Journal Article in ACTA CLINICA BELGICA

Outcome in noninvasively and invasively ventilated hematologic patients with acute respiratory failure

Pieter DepuydtDOMINIQUE BENOITKoenraad VandewoudeJohan DecruyenaereFrancis Colardyn

A1 Journal Article in CHEST

2003

Invasive aspergillosis in ICU patients: Analysis for risk factors and mortality

Koenraad VandewoudeStijn BlotPieter DepuydtFrancis Colardyn

2002

Effect of ozone exposure on allergic sensitization and airway inflammation induced by dendritic cells.

Pieter DepuydtBart LambrechtGuy JoosRomain Pauwels

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Outcome in critically ill hematologic cancer patients : impact of bacterial infection

Dominique BenoitPhilippe DecruyenaereRenaat PelemanPieter DepuydtKoenraad VandewoudeFrancis Colardyn