Research Explorer

Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.

Researcher

Pieter De Bleser

35 Results

2022

CARD14 signalling ensures cell survival and cancer associated gene expression in prostate cancer cells

Domien VannesteJens StaalMira HaegmanYasmine DriegeMarieke CarelsElien Van NuffelPieter De BleserYvan SaeysRudi BeyaertInna Afonina

A1 Journal Article in BIOMEDICINES

GTF3A mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the host-derived RIG-I ligand RNA5SP141

Leslie NaesensJosephine NemegeerDelfien BogaertKatrien StaesVeronique DebackerPieter De BleserMarieke De BruyneElfride De BaereBart LambrechtJens StaalTessa KerreRudi BeyaertJonathan MaelfaitSimon TavernierFilomeen Haerynck

A1 Journal Article in SCIENCE IMMUNOLOGY

2020

Comparison of the PU.1 transcriptional regulome and interactome in human and mouse inflammatory dendritic cells

Pieter De Bleser

A1 Journal Article in JOURNAL OF LEUKOCYTE BIOLOGY

2019

Next-generation muscle-directed gene therapy by in silico vector design

Pieter De Bleser

A1 Journal Article in NATURE COMMUNICATIONS

Single-cell RNA sequencing of the T helper cell response to house dust mites defines a distinct gene expression signature in airway Th2 cells

Liesbet MartensKim DeswarteBart LambrechtPieter De BleserHamida HammadYvan Saeys

A1 Journal Article in IMMUNITY

Stellate cells, hepatocytes, and endothelial cells imprint the Kupffer cell identity on monocytes colonizing the liver macrophage niche

Johnny BonnardelWouter T'JonckDjoere GaublommeRobin BrowaeysCharlotte ScottLiesbet MartensBavo VannesteSofie De PrijckAnna KremerEvelien Van HammePeter BorghgraefWendy ToussaintPieter De BleserBart LambrechtTom TaghonSaskia LippensDirk ElewautYvan SaeysMartin Guilliams

A1 Journal Article in IMMUNITY

2018

Mechanical strain determines the site-specific localization of inflammation and tissue damage in arthritis

Isabelle CambréDjoere GaublommeArne BurssensPeggy JacquesNadia SchryversAmélie De MuynckLeander MeurisStijn LambrechtPieter De BleserYvan SaeysLuc Van HoorebekePaul SimoensNico CallewaertDirk Elewaut

A1 Journal Article in NATURE COMMUNICATIONS

The transcription factor ZEB2 is required to maintain the tissue-specific identities of macrophages

Charlotte ScottWouter T'JonckLiesbet MartensHelena TodorovDorine SichienBieke SoenJohnny BonnardelSofie De PrijckNiels VandammeRobrecht CannoodtWouter SaelensBavo VannesteWendy ToussaintPieter De BleserNozomi TakahashiPeter VandenabeeleBart LambrechtGeert BerxYvan SaeysMartin Guilliams

A1 Journal Article in IMMUNITY

2017

ConTra v3 : a tool to identify transcription factor binding sites across species, update 2017

Arne SoetePaco HulpiauYvan SaeysPieter De Bleser

A1 Journal Article in NUCLEIC ACIDS RESEARCH

Differential expression of lncRNAs during the HIV replication cycle: an underestimated layer in the HIV-host interplay (vol 6, 36111, 2016)

Wim TrypsteenClarissa Van HeckePieter MestdaghSteve LefeverYvan SaeysPieter De BleserJo VandesompeleLinos VandekerckhoveWard De Spiegelaere

lncRNA discovery in the HIV replication cycle adds new layer in HIV-host interplay

Wim TrypsteenClarissa Van HeckePieter MestdaghSteve LefeverPieter De BleserJo VandesompeleWard De SpiegelaereLinos Vandekerckhove

2016

Differential expression of lncRNAs during the HIV replication cycle : an underestimated layer in the HIV-host interplay

Wim TrypsteenClarissa Van HeckePieter MestdaghSteve LefeverYvan SaeysPieter De BleserJo VandesompeleLinos VandekerckhoveWard De Spiegelaere

A1 Journal Article in SCIENTIFIC REPORTS

GATA1-deficient dendritic cells display impaired CCL21-dependent migration toward lymph nodes due to reduced levels of polysialic acid

Filipe Branco MadeiraPieter De BleserYvan SaeysHamida HammadBart Lambrecht

A1 Journal Article in JOURNAL OF IMMUNOLOGY

αT-catenin in restricted brain cell types and its potential connection to autism

Koen TybergheinPieter De BleserJolanda van HengelFrans Van Roy

A2 Journal Article in JOURNAL OF MOLECULAR PSYCHIATRY

2015

Genome-wide computational analysis reveals cardiomyocyte-specific transcriptional cis-regulatory motifs that enable efficient cardiac gene therapy

Pieter De Bleser

A1 Journal Article in MOLECULAR THERAPY

2014

Computationally designed liver-specific transcriptional modules and hyperactive factor IX improve hepatic gene therapy

Pieter De Bleser

A1 Journal Article in BLOOD

Developing algorithms for the in silico identification of transcription factor binding sites

Stefan BroosFrans Van RoyPieter De Bleser

Liver-specific transcriptional modules identified by genome-wide in silico analysis enable efficient gene therapy in mice and non-human primates

Pieter De Bleser

A1 Journal Article in MOLECULAR THERAPY

2013

PhysBinder : improving the prediction of transcription factor binding sites by flexible inclusion of biophysical properties

Stefan BroosArne SoeteBart HoogheFrans Van RoyPieter De Bleser

A1 Journal Article in NUCLEIC ACIDS RESEARCH

2012

A flexible integrative approach based on random forest improves prediction of transcription factor binding sites

Bart HoogheStefan BroosFrans Van RoyPieter De Bleser

A1 Journal Article in NUCLEIC ACIDS RESEARCH

2011

ConTra v2 : a tool to identify transcription factor binding sites across species, update 2011

Stefan BroosPaco HulpiauJeroen GalleBart HoogheFrans Van RoyPieter De Bleser

A1 Journal Article in NUCLEIC ACIDS RESEARCH

In silico approaches to studying transcriptional gene regulation: prediction of transcription factor binding sites and applications thereof

Bart HoogheFrans Van RoyPieter De Bleser

Nanobodies® specific for respiratory syncytial virus fusion protein protect against infection by inhibition of fusion

Bert SchepensLorena IbanezSarah De BaetsPieter BogaertPieter De BleserFrederik VervalleXavier Saelens

A1 Journal Article in JOURNAL OF INFECTIOUS DISEASES

2009

Human metallothionein expression under normal and pathological conditions : mechanisms of gene regulation based on in silico promoter analysis

Debby LaukensAnouk WaeytensPieter De BleserClaude CuvelierMartine De Vos

A1 Journal Article in CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

2008

ConTra: a promoter alignment analysis tool for identification of transcription factor binding sites across species

Bart HooghePaco HulpiauFrans Van RoyPieter De Bleser

A1 Journal Article in NUCLEIC ACIDS RESEARCH

Low nucleosome occupancy is encoded around functional human transcription factor binding sites

Frans Van RoyPieter De Bleser

A1 Journal Article in BMC GENOMICS

ORegAnno: an open-access community-driven resource for regulatory annotation

Bart HooghePieter De Bleser

A1 Journal Article in NUCLEIC ACIDS RESEARCH

2007

A distance difference matrix approach to identifying transcription factors that regulate differential gene expression

Pieter De BleserBart HoogheDominique VliegheFrans Van Roy

A1 Journal Article in GENOME BIOLOGY

2006

A new generation of JASPAR, the open-access repository for transcription factor binding site profiles

Dominique VlieghePieter De BleserKris VleminckxFrans Van Roy

A1 Journal Article in NUCLEIC ACIDS RESEARCH

2001

Identification of tumor necrosis factor (TNF) amino acids crucial for binding to the murine p75 TNF receptor and construction of receptor-selective mutants.

Paul AmelootWalther FiersPieter De BleserPeter VandenabeelePeter Brouckaert

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

2000

Antioxidant enzyme gene expression in rats with remnant kidney induced chronic renal failure

Dirk De CraemerPieter De Bleser

A1 Journal Article in EXPERIMENTAL NEPHROLOGY

Renal antioxidant enzymes and fibrosis-related markers in the rat adriamycin model

Dirk De CraemerPieter De Bleser

A1 Journal Article in NEPHRON

1998

Purification of hepatic stellate cells by side scatter activated cell sorting

Dirk De CraemerPieter De Bleser

Purification of rat hepatic stellate cells by side scatter-activated cell sorting

Dirk De CraemerPieter De Bleser

A1 Journal Article in HEPATOLOGY

1997

Purification of hepatic stellate cells by side scatter activated cell sorting

Dirk De CraemerPieter De Bleser