Research Explorer

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Researcher

Pierre De Clercq

Publications & Research Data

Awards & Distinctions

205 Results

2022

We need to talk about Kekule : the 150th anniversary of the benzene structure

Pierre De Clercq

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

2019

WY 1048, a 17-methyl 19-nor D-ring analog of vitamin D3, in combination with risedronate restores bone mass in a mouse model of postmenopausal osteoporosis

Stefanie DomsLieve VerlindenJustine VanhevelIris JanssensRoger BouillonPierre De ClercqAnnemieke Verstuyf

A1 Journal Article in JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

2015

Possibility of [1,5] sigmatropic shifts in bicyclo[4.2.0]octa-2,4-dienes

Hannelore GoossensJohan WinneSebastian WoutersLaura HermosillaPierre De ClercqMichel WaroquierVeronique Van SpeybroeckSaron Catak

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

Total synthesis of biologically active polycyclic terpenoids: frondosanes, liphaganes, guaianolides, zizaanes and calcitriols

Duchan LaplaceJohan WinnePierre De Clercq

2014

1,25-Dihydroxyvitamin D-3 and its analog TX527 promote a stable regulatory T cell phenotype in T cells from type 1 diabetes patients

Tom L Van BelleAn-Sofie VanherwegenDorien FeyaertsPierre De ClercqAnnemieke VerstuyfHannelie KorfConny GysemansChantal Mathieu

A1 Journal Article in PLOS ONE

A proteomic approach on the effects of TX527, a 1α,25-dihydroxyvitamin D₃ analog, in human T lymphocytes

GB FerreiraF BaekeA VerstuyfPierre De ClercqE WaelkensC MathieuL Overbergh

A1 Journal Article in JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Cell cycle arrest and apoptosis induced by 1α,25(OH)₂D₃ and TX527 in Kaposi sarcoma is VDR dependent

Verónica González-PardoAlejandra SuaresAnnemieke VerstuyfPierre De ClercqRicardo BolandAna Russo de Boland

A1 Journal Article in JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

2013

Convenient and versatile route to 2-alkyl-19-nor-analogues of calcitriol

Duchan LaplaceMichel Van OverscheldeJohan WinneAnnemieke VerstuyfPierre De Clercq

Synthesis of 2-ethyl-19-nor analogs of 1α,25-dihydroxyvitamin D₃

Duchan LaplaceMichel Van OverscheldePierre De ClercqAnnemieke VerstuyfJohan Winne

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

The vitamin D analog TX527 ameliorates disease symptoms in a chemically induced model of inflammatory bowel disease

Lieve VerlindenCarlien LeyssensIne BeullensSuzanne MarcelisChantal MathieuPierre De ClercqAnnemieke Verstuyf

A1 Journal Article in JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

2012

A convenient and versatile route to 2-alkyl-19-nor-analogs of calcitriol

Duchan LaplaceMichel Van OverscheldeJohan WinneAnnemieke VerstuyfPierre De Clercq

Applications of (4+3) cycloaddition reactions of furfuryl cations

Duchan LaplaceBart VerbraekenBram DenooMaria Gomez RodriguezNiels PicardNick VanhulleJohan WinnePierre De Clercq

2011

Analogs of calcitriol

Lieve VerlindenGuy EelenRoger BouillonMaurits VandewallePierre De ClercqAnnemieke Verstuyf

Bookchapter in Vitamin D

2010

CD-ring modified vitamin D-3 analogs and their superagonistic action

Guy EelenLieve VerlindenRoger BouillonPierre De ClercqAlberto MuñozAnnemieke Verstuyf

A1 Journal Article in JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Cyclopentanones XIV : the synthesis of a prostanoid synthon starting from 3-alkyl-1,2,4-cyclopentanetriones

W. van BrusselJ. van HoolandPierre De ClercqMaurits Vandewalle

A2 Journal Article in BULLETIN DES SOCIÉTÉS CHIMIQUES BELGES

Cyclopentanones XVII : prostaglandin synthesis involving the lithium-liquid ammonia reduction of 3-alkyl-4-hydroxy-2-(1′-octynyl)-2-cyclopentenones

Pierre De ClercqM. De SmetK. LegeinF. VanhulleMaurits Vandewalle

A2 Journal Article in BULLETIN DES SOCIÉTÉS CHIMIQUES BELGES

2009

Antiproliferative and Calcemic Actions of Trans-Decalin CD-Ring Analogs of 1,25-Dihydroxyvitamin D-3

Guy EelenLieve VerlindenJos LaureysSuzanne MarcelisPierre De ClercqChantal MathieuRoger BouillonAnnemieke Verstuyf

A1 Journal Article in ANTICANCER RESEARCH

Development of Analogues of 1 alpha,25-Dihydroxyvitamin D-3 with Biased Side-Chain Orientation: C20 Methylated Des-C,D-homo Analogues

Freek VrielynckDirk Van HaverMaurits VandewalleLieve VerlindenAnnemieke VerstuyfRoger BouillonGianluca CrocePierre De Clercq

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Microarray analysis of MCF-7 breast cancer cells treated with 1,25-dihydroxyvitamin D-3 or a 17-methyl-D-ring analog

Els VanoirbeekGuy EelenLieve VerlindenKathleen MarchalKristof EngelenBart De MoorIne BeullensSuzanne MarcelisPierre De ClercqRoger Bouillon et al.

A1 Journal Article in ANTICANCER RESEARCH

Synthesis of 1 alpha,25-Dihydroxyvitamin D Analogues Featuring a S-2-symmetric CD-ring Core

Pierre De ClercqGarrett Minne

A1 Journal Article in MOLECULES

Synthesis of 22-oxaspiro[4.5]decane CD-ring modified analogs of 1 alpha,25-dihydroxyvitamin D3

Frederik De BuysserLieve VerlindenAnnemieke VerstuyfPierre De Clercq

A1 Journal Article in TETRAHEDRON LETTERS

2008

Microarray analysis of MCF-7 breast cancer cells treated with 1,25-(OH)(2)D-3 or the analog WY1112

Els VanoirbeekGuy EelenIne BeullensMark Van CampKristof EngelenKathleen MarchalPierre De ClercqM VandewalleRoger BouillonAnnemieke Verstuyf

Nonenzymic polycyclisation of analogues of oxidosqualene with a preformed C-ring

Johan WinnePierre De ClercqM MILANESIOP PATTISOND VITERBO

A1 Journal Article in ORGANIC & BIOMOLECULAR CHEMISTRY

Ontwikkeling van analogen van calcitriol met opgedrongen zijketenoriëntatie

Freek VrielynckPierre De Clercq

Ontwikkeling van decaline analogen van calcitriol

Garrett MinnePierre De Clercq

Superagonistic Fluorinated Vitamin D3 analogs Stabilize Helix 12 of the Vitamin D receptor

Guy EelenNoelia ValleYoshiteru SatoNatasha RochelLieve VerlindenPierre De ClercqDino MorasRoger BouillonAlberto MunozAnnemieke Verstuyf

A1 Journal Article in Chemistry & Biology

Synthesis of a tripodal scaffold for solid phase synthesis of artificial receptors

Steven Van der PlasAn GeaSara FigaroliPierre De ClercqAnnemieke Madder

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

2007

Asymmetric synthesis of the epimeric (3S)-3-((E)-Hex-1-eny1)-2-methylcyclohexanones

Freek VrielynckPierre De Clercq

A1 Journal Article in MOLECULES

Fast and easy detection of aromatic amines on solid support

Steven Van der PlasPierre De ClercqAnnemieke Madder

A1 Journal Article in TETRAHEDRON LETTERS

Mechanism and potential of the growth-inhibitory actions of vitamin D and analogs

G EELENC GYSEMANSL VERLINDENE VANOIRBEEKPierre De ClercqDirk Van HaverC MATHIEUR BOUILLONA VERSTUYF

A1 Journal Article in CURRENT MEDICINAL CHEMISTRY

Removal of C-ring from the CD-ring skeleton of 1 alpha,25-dihydroxyvitamin D-3 does not alter its target tissue metabolism significantly

GS REDDYM ROBINSONG WANGGTR PALINOREL GENNAROP VOUROSPierre De ClercqMaurits VandewalleW YONGS LING et al.

A1 Journal Article in ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Synthesis of 3,4,7,8-Tetrahydronaphthalene-1,5(2H,6H)-dione

Garrett MinnePierre De Clercq

A1 Journal Article in MOLECULES

The development of CD-ring modified analogs of 1 alpha,25-dihydroxyvitamin D

Pierre De ClercqFrederik De BuysserGarrett MinneW SCHEPENSFreek VrielynckDirk Van HaverM VANDEWALLEA VERSTUYFR BOUILLON

A1 Journal Article in JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

2006

Application of the B-alkyl Suzuki-Miyaura cross-coupling reaction to the stereoselective synthesis of analogues of (3S)-oxidosqualene

Johan WinneB GUANGJo D'herdePierre De Clercq

A1 Journal Article in ORGANIC LETTERS

Application of the solid-phase Julia-Lythgoe olefination in vitamin D side-chain construction

Jo D'herdePierre De Clercq

A1 Journal Article in MOLECULES

Asymmetric synthesis of (7aS)-7a-methyl-4,5,7,7a-tetrahydro-1H-indene-2,6-dione and useful derivatives thereof

Samuël DeminDirk Van HaverPierre De Clercq

A1 Journal Article in MOLECULES

Solid-supported synthesis of highly functionalized tripodal peptides with flexible but preorganized geometry: towards potential serine protease mimics

An GeaNadia FarcyNúria Roqué i RossellJosé MartinsPierre De ClercqAnnemieke Madder

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of spiro[4.5] decane CF-ring analogues of 1 alpha,25-dihydroxyvitamin D-3

Wim SchepensDirk Van HaverMaurits VandewalleR BOUILLONA VERSTUYFPierre De Clercq

A1 Journal Article in ORGANIC LETTERS

Vitamin D analogs and coactivators

G EELENL VERLINDENPierre De ClercqMaurits VandewalleR BOUILLONA VERSTUYF

A1 Journal Article in ANTICANCER RESEARCH

2005

1,25-Dihydroxyvitamin D-3 and analogues protect primary human keratinocytes against UVB-induced DNA damage

P DE HAESM GARMYNA VERSTUYFPierre De ClercqMaurits VandewalleH DEGREEFK VANTIEGHEMR BOUILLONS SEGAERT

A1 Journal Article in JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Altered Vitamin D receptor-coactivator interactions reflect superagonism of Vitamin D analogs

G EELENL VERLINDENM VAN CAMPF CLAESSENSPierre De ClercqMaurits VandewalleR BOUILLONA VERSTUYF

A1 Journal Article in JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Fine-tuning furan toxicity: fast and quantitative DNA interchain crosslink formation upon selective oxidation of a furan containing oligonucleotide

S HALILAT VELASCOPierre De ClercqAnnemieke Madder

A1 Journal Article in CHEMICAL COMMUNICATIONS

Mechanisms for the selective action of Vitamin D analogs

R BOUILLONL VERLINDENG EELENPierre De ClercqMaurits VandewalleC MATHIEUA VERSTUYF

A1 Journal Article in JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Superagonistic action of 14-epi-analogs of 1,25-dihydroxyvitamin D explained by vitamin D receptor-coactivator interaction

G EELENL VERLINDENN ROCHELF CLAESSENSPierre De ClercqMaurits VandewalleG TOCCHINI-VALENTINID MORASR BOUILLONA VERSTUYF

A1 Journal Article in MOLECULAR PHARMACOLOGY

Synthesis of 2-methyl and ethyl-substituted 19-nor-1 alpha,25-dihydroxyvitamin D-3 analogues via the cyclovitamin strategy

YR ZHAOB GUANGR BOUILLONA VERSTUYFPierre De ClercqMaurits Vandewalle

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

2004

Biological activity and conformational analysis of C20 and C14 epimers of CD-ring modified trans-decalin 1 alpha,25-dihydroxyvitamin D analogs

Pierre De ClercqIbrahim MuradLing-Jie GaoYong-Jun ChenDirk Van HaverMaurits VandewalleAnnemieke VerstuyfLieve VerlindenChristel VerbovenRoger Bouillon

A1 Journal Article in JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1 α,25-dihydroxyvitamin D3 : cis-perhydrindane CE-ring analogues

Samuël DeminDirk Van HaverMaurits VandewallePierre De ClercqR BouillonA Verstuyf

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1 α,25-dihydroxyvitamin D3 : spiro[5.5]undecane CF-ring analogues

Wim SchepensDirk Van HaverMaurits VandewallePierre De ClercqR BouillonA Verstuyf

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Two 14-epi analogues of 1,25-dihydroxyvitamin D-3 protect human keratinocytes against the effects of UVB

P DE HAESM GARMYNA VERSTUYFPierre De ClercqMaurits VandewalleK VANTIEGHEMH DEGREEFR BOUILLONS SEGAERT

A1 Journal Article in ARCHIVES OF DERMATOLOGICAL RESEARCH

2003

Carbon-carbon bond formation on solid support : application of the classical Julia-Lythgoe olefination

Jo D'herdePierre De Clercq

A1 Journal Article in TETRAHEDRON LETTERS

Previtamin D3 with a trans-fused decalin CD-ring has pronounced genomic activity

L VerlindenS VerstuyfC VerbovenG EelenC De RanterLJ GaoY ChenIbrahim MuradM ChoiK Yamamoto et al.

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Synthesis and binding affinity studies of muscarinic receptor antagonists related to dehydrohimbacine

LJ GaoGunther Van CauwenbergeNoël HostenDirk Van HaverM WaelbroeckPierre De Clercq

A1 Journal Article in ARKIVOC

Synthesis, biological activity, and conformational analysis of CD-ring modified trans-decalin 1 alpha,25-dihydroxyvitamin D analogs

YJ CHENLJ GAOIbrahim MuradA VERSTUYFL VERLINDENC VERBOVENR BOUILLOND VITERBOM MILANESIODirk Van Haver et al.

A1 Journal Article in ORGANIC & BIOMOLECULAR CHEMISTRY

2002

A novel short convergent entry into himbacine derivatives

G Van CauwenbergeLJ GaoDirk Van HaverM MilanesioD ViterboPierre De Clercq

A1 Journal Article in ORGANIC LETTERS

An intramolecular Furan-Diene Diels-Alder approach to 11-oxo 10 alpha-steroids

Sandra ClaeysDirk Van HaverPierre De ClercqM MILANESIOD VITERBO

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Evaluation of a two-stage screening procedure in the combinatorial search for serine protease-like activity

Annemieke MadderL LIHilde De MuynckNadia FarcyDirk Van HaverFranky FantG VANHOENACKERPatrick SandraAP DAVISPierre De Clercq

A1 Journal Article in JOURNAL OF COMBINATORIAL CHEMISTRY

Peptide sequence determination of peptidosteroids on a single bead by electrospray ionization-mass spectroscopy.

G VANHOENACKERL LIUFrederic LynenAnnemieke MadderPierre De ClercqPatrick Sandra

A1 Journal Article in JOURNAL OF SEPARATION SCIENCE

Synthesis and affinity studies of himbacine derived muscarinic receptor antagonists

LJ GAOM WAELBROECKSven HofmanDirk Van HaverM MILANESIOD VITERBOPierre De Clercq

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Vitamin D-3 : synthesis of seco-C-9,11-bisnor-17-methyl-1 alpha, 25-dihydroxyvitamin D-3 analogues

YS WUPierre De ClercqMaurits VandewalleR BOUILLONA VERSTUYF

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Vitamin D-3: Synthesis of seco C-9,11,21-trisnor-17-methyl-1 alpha, 25-dihydroxyvitamin D-3 analogues.

YS WUKatrien SabbePierre De ClercqMaurits VandewalleR BOUILLONA VERSTUYF

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Vitamin D-3: Synthesis of seco C-9,11,21-trisnor-17-methyl-1 alpha,25-dihydroxyvitamin D-3 analogues (vol 12, pg 1629, 2002).

YS WUKatrien SabbePierre De ClercqMaurits VandewalleR BOUILLONA VERSTUYF

2001

A pentaerythritol-based molecular scaffold for solid-phase combinatorial chemistry

Nadia FarcyHilde De MuynckAnnemieke MadderN HOSTENPierre De Clercq

A1 Journal Article in ORGANIC LETTERS

A practical synthesis of 14-epi-19-nor-1a, 25-dihydroxyvitamin D3 analogues and their a-ring epimers

YS WUYR ZHAOHJ TIANPierre De ClercqMaurits VandewalleM BERTHIERG PELLEGRINOP MAILLOSJC PASCAL

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A short intramolecular Diels-Alder route to himbacine derivatives

Sven HofmanLJ GAOHilde Van DingenenN HOSTENDirk Van HaverPierre De ClercqM MILANESIOD VITERBO

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Development of analogues of 1 alpha,25-dihydroxyvitamin D-3 with biased side chain orientation : methylated des-C,D-homo analogues

Stefan GabrielsDirk Van HaverMaurits VandewallePierre De ClercqA VERSTUYFR BOUILLON

A1 Journal Article in CHEMISTRY-A EUROPEAN JOURNAL

Interaction of two novel 14-epivitamin D-3 analogs with vitamin D-3 receptor-retinoid X receptor heterodimers on vitamin D-3 responsive elements

L VERLINDENA VERSTUYFM QUACKM VAN CAMPE VAN ETTENPierre De ClercqMaurits VandewalleC CARLBERGR BOUILLON

A1 Journal Article in JOURNAL OF BONE AND MINERAL RESEARCH

2000

A model for the nonenzymatic BCD cyclization of squalene

SZ ZHOUMario SeyPierre De ClercqM MILANESIOD VITERBO

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Application of combinatorial procedures in the search for serine-protease-like activity with focus on the acyl transfer step

Hilde De MuynckAnnemieke MadderNadia FarcyPierre De ClercqMN PEREZ-PAYANLM OHBERGAP DAVIS

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetrization of all-cis-3,5-dihydroxy1-(methoxycarbonyl)cyclohexane and of the 4-methyl and 4-ethyl substituted homologues

YR ZHAOYS WUPierre De ClercqMaurits VandewalleP MAILLOSJC PASCAL

A1 Journal Article in TETRAHEDRON-ASYMMETRY

Biological activity of CD-ring modified 1 alpha,25-dihydroxyvitamin D analogues : C-ring and five-membered D-ring analogues

A VERSTUYFL VERLINDENE VAN ETTENL SHIYS WUChristiaan D'HalleweynDirk Van HaverGD ZHUYJ CHENXM ZHOU et al.

A1 Journal Article in JOURNAL OF BONE AND MINERAL RESEARCH

Convergent synthesis of 1 alpha-hydroxyvitamin D-5

LJ GAOXY ZHAOMaurits VandewallePierre De Clercq

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Two novel 14-epi-analogues of 1,25-dihydroxyvitamin D-3 inhibit the growth of human breast cancer cells in vitro and in vivo

L VERLINDENA VERSTUYFM VAN CAMPS MARCELISKatrien SabbeXY ZHAOPierre De ClercqMaurits VandewalleR BOUILLON

A1 Journal Article in CANCER RESEARCH

1999

Novel sensitive colorimetric assay for visual detection of solid-phase bound amines

Annemieke MadderNadia FarcyNoël HostenHilde De MuynckPierre De ClercqJohn BarryAnthony P. Davis

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

On the unexpected stereochemical outcome of the magnesium in methanol : conjugate reduction of an exocyclic alpha,beta-unsaturated ester

Stefan GabrielsDirk Van HaverMaurits VandewallePierre De ClercqDavide Viterbo

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis, biological activity, and conformational analysis of four seco-D-15,19-bisnor-1 alpha,25-dihydroxyvitamin D analogues, diastereomeric at C17 and C20

XM ZHOUGD ZHUDirk Van HaverMaurits VandewallePierre De ClercqA VERSTUYFR BOUILLON

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

1998

On the use of volume maps in the conformational analysis of vitamin D analogs

Dirk Van HaverPierre De Clercq

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Stepwise approach toward first generation nonenzymatic hydrolases

Annemieke MadderPierre De ClercqJean-Paul Declercq

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

Studies directed towards the total synthesis of (+)-himbacine

Sven HofmanGovert De BaeckeB KendaPierre De Clercq

A1 Journal Article in SYNTHESIS-STUTTGART

The biological activity of nonsteroidal vitamin D hormone analogs lacking both the C- and D-rings

A VerstuyfL VerlindenH Van BaelenKatrien SabbeChristiaan D'HalleweynPierre De ClercqMaurits VandewalleR Bouillon

A1 Journal Article in JOURNAL OF BONE AND MINERAL RESEARCH

1997

Biotin : a timeless challenge for total synthesis

Pierre De Clercq

A1 Journal Article in CHEMICAL REVIEWS

Estramicins : a novel cyclic diyl precursor derived from estradiol

Christel MeertJ WangPierre De Clercq

A1 Journal Article in TETRAHEDRON LETTERS

Mechanism of esterification of 1,3-dimethylamino alcohols by N-acetylimidazole in acetonitrile and the influence of alkyl and geminal dialkyl substitution upon the rate

Annemieke MadderS SEBASTIANDirk Van HaverPierre De ClercqH MASKILL

A1 Journal Article in JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2

Structure-reactivity relationships in the rate of esterification by acetylimidazole : the influence of the second hydroxy group and of the length of the N-omega-hydroxy-n-alkyl chain in 3-(N-methyl, N-omega-hydroxy-n-alkyl)amino-2-tert-butylpropan-1-ols

Annemieke MadderPierre De ClercqHoward Maskill

A1 Journal Article in JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2

Synthesis and biological evaluation of 1 alpha-hydroxy-25(R and S)-25,26-epoxy-23-yne vitamin D-3 and of 1a,25(R and S),26-trihydroxy-23-yne vitamin D-3

Yusheng WuXu-Yang ZhaoPierre De ClercqMaurits VandewalleR BouillonA Verstuyf

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of CD-ring modified 1 alpha,25-dihydroxy vitamin D analogues : five-membered D-ring analogues

W YongS LingChristiaan D'HalleweynDirk Van HaverPierre De ClercqMaurits Vandewalle

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The synthesis of CD-ring modified 1α,25-dihydroxy vitamin D analogues : six-membered D-ring analogues I

Bruno LinclauPierre De ClercqMaurits Vandewalle

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The synthesis of CD-ring modified 1α,25-dihydroxy vitamin D analogues : six-membered D-ring analogues II

Bruno LinclauPierre De ClercqMaurits VandewalleR. BouillonA. Verstuyf

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The synthesis of di(hydroxyalkyl) substituted bicyclic guanidines

Annemieke MadderI MunsterU. RollePierre De Clercq

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

Total synthesis of 1 alpha,25-dihydroxy-18-norvitamin D-3

Benedikt SasPierre De ClercqMaurits Vandewalle

A1 Journal Article in SYNLETT

1996

Estramycins : a potential acyclic diyl precursor derived from estradiol

Jing WangPierre De Clercq

A1 Journal Article in TETRAHEDRON LETTERS

Synthesis of CD-ring modified 1 alpha,25-dihydroxy vitamin D analogues : C-ring analogues

G. D. ZhuY. J. ChenX. M. ZhouMaurits VandewallePierre De Clercq

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of CD-ring modified 1 alpha,25-dihydroxy vitamin D analogues : E-ring analogues

Katrien SabbeChristiaan D'HalleweynPierre De ClercqMaurits Vandewalle

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of new vitamin D-3 analogues with a decalin-type CD-ring

YJ ChenPierre De ClercqMaurits Vandewalle

A1 Journal Article in TETRAHEDRON LETTERS

1995

Biological evaluation of epoxy analogs of 1-alpha,25-dihydroxyvitamin-D-3

K ALLEWAERTXY ZHAOJ ZHAOF GLIBERTD BRANISTEANUPierre De ClercqMaurits VandewalleR BOUILLON

A1 Journal Article in STEROIDS

Estramycins : a new diyl precursor family derived from estradiol

J WANGPierre De Clercq

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH

Intramolecular Diels-Alder reaction with furan-diene : syntheses of gibberellins (+)-GA(1) AND (+)-GA(3)

Frank NuyttensJ HOFLACKG APPENDINOPierre De Clercq

A1 Journal Article in SYNLETT

Novel enantioselective synthesis of (+)-biotin.

Frederik DeroosePierre De Clercq

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

Polyene cyclizations related to oxidosqualene cyclization : a model for the anti-markovnikov closure of ring-C

Karla BerckmoesPierre De ClercqD VITERBO

A1 Journal Article in JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Studies directed towards the total synthesis of (±)-himbacine

Govert De BaeckePierre De Clercq

A1 Journal Article in TETRAHEDRON LETTERS

Synthesis of a chiral DI(hydroxyalkyl) substituted bicyclic guanidine

I MUNSTERU ROLLEAnnemieke MadderPierre De Clercq

A1 Journal Article in TETRAHEDRON-ASYMMETRY

Synthesis of enantiomerically pure (R)-3-methyl-2-cyclopenten-1-OL and (S)-3-methyl-2-cyclopenten-1-OL

XM ZHOUPierre De ClercqJ GAWRONSKI

A1 Journal Article in TETRAHEDRON-ASYMMETRY

1994

11-fluoro-1-alpha-hydroxyvitamin D-3 : the quest for experimental evidence of the folded vitamin-D conformation

GD ZHUDirk Van HaverH JURRIAANSPierre De Clercq

A1 Journal Article in TETRAHEDRON

A novel enantioselective synthesis of (+)-biotin

FD DEROOSEPierre De Clercq

A1 Journal Article in TETRAHEDRON LETTERS

Intramolecular diels-alder reaction of 8-trifluoromethyl-1,3,8-nonatrienes : an access to angular trifluoromethylated hydrindenes

GD ZHUBart Van LanckerDirk Van HaverPierre De Clercq

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

The biological-activity of 23-oxa-dihydroxyvitamin-D-3, 23-oxa-24-oxo-dihydroxyvitamin-D-3, and 23-thia-dihydroxyvitamin-D-3

Katrien AllewaertRenilde ConventsBiauw Keng TanSuzanne MarcelisJie ZhaoXu-yang ZhaoPierre De ClercqMaurits VandewalleRoger Bouillon

A1 Journal Article in STEROIDS

Total synthesis of periplanone-B via intramolecular Diels-Alder reaction with furan-diene and allene-dienophile

Tom De GeyterSerge CauwberghsPierre De Clercq

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

1993

A novel enantioselective synthesis of (+)-biotin

Frederik DeroosePierre De Clercq

A1 Journal Article in TETRAHEDRON LETTERS

A novel synthesis of an A-ring precursor to 1-alpha-hydroxyvitamin-D

Johny De SchrijverPierre De Clercq

A1 Journal Article in TETRAHEDRON LETTERS

Biologic activity of dihydroxylated 19-nor-(pre)vitamin-D(3)

Roger BouillonLuis A. SarandesesKatrien AllewaertJie ZhaoJ. Luis MascareñasAntonio MouriñoSara VrielynckPierre De ClercqMaurits Vandewalle

A1 Journal Article in JOURNAL OF BONE AND MINERAL RESEARCH

Rate acceleration of the intramolecular diels-alder reaction with furan-diene by anchoring substitution : the T-butyl effect revisited

Frans De CorteFrank NuyttensSerge CauwberghsPierre De Clercq

A1 Journal Article in TETRAHEDRON LETTERS

Synthesis and biological evaluation of 23-oxa-24-oxo-1α,25-dihydroxyvitamin-D3, 23-thia-24-oxo-1α,25-dihydroxyvitamin-D3 and 23-oxa-24-oxo-1α,25-dihydroxyvitamin-D3

Katrien AllewaertH. Van BaelenRoger BouillonXu-yang ZhaoPierre De ClercqMaurits Vandewalle

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and biological evaluation of some 25,26-epoxy-1α,24-dihydroxyvitamin-D3 analogues

Xu-yang ZhaoPierre De ClercqMaurits VandewalleKatrien AllewaertH. Van BaelenRoger Bouillon

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The influence of anchoring substitution in 1,3-amino alcohols on the rate and mechanism of esterification by acetylimidazole and by P-nitrophenyl acetate

I STEELSPierre De ClercqH MASKILL

A1 Journal Article in JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS

1992

Anchoring substitution in acyclic 1,3-amino alcohols : asymmetric reductions with chiral modifications of lithium aluminum-hydride and borane

I STEELSPierre De ClercqJP DECLERCQ

A1 Journal Article in TETRAHEDRON-ASYMMETRY

Structure-function analysis of vitamin-D analogs with C-ring modifications

Roger BOUILLONKatrien ALLEWAERTJohannes PTM VAN LEEUWENBiauw-Keng TanDa Zhen XiangPierre De ClercqMaurits VandewalleHuibert AP PolsMartine P BosHugo Van Baelen et al.

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

SYNTHESIS OF (C-11)-SUBSTITUTED ANALOGS OF 1-ALPHA,25-DIHYDROXYVITAMIN-D3.

Christiaan D'HalleweynDirk Van HaverJohan Van der EyckenPierre De ClercqMaurits Vandewalle

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of (C-11)-substituted analogues of 1α,25-dihydroxyvitamin D3

Christiaan D'HalleweynDirk Van HaverJohan Van der EyckenPierre De ClercqMaurits Vandewalle

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

1991

An improved synthesis of 1-alpha-hydroxy vitamin D3.

W NERINCKXPierre De ClercqC COUWENHOVENW OVERBEEKS HALKES

A2 Journal Article in TETRAHEDRON

The intramolecular Diels-Alder reaction with furan-diene : a novel route to (+/-)-gibberellin A5

Frank NuyttensGiovanni AppendinoPierre De Clercq

A1 Journal Article in SYNLETT

1990

Intramolecular Diels-Alder reaction with furan-diene and allene-dienophile : application in steroid synthesis

Patrick MissiaenPierre De Clercq

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

1989

The stereochemistry and solid state conformation of 1,10β-epoxyachillin

JA MarcoO BarberaJ LexPierre De ClercqAndré De Bruyn

A1 Journal Article in JOURNAL OF NATURAL PRODUCTS

1988

A novel approach to periplanone-B involving an intramolecular Diels-Alder reaction with furan-diene and allene-dienophile

Pierre De ClercqSerge Cauwberghs

A1 Journal Article in TETRAHEDRON LETTERS

Anchoring substitution in acyclic fragments : a topical basis for enhanced diastereofacial selection in the Diels-Alder reaction to chiral acrylates

Filip A. J. De CortePierre De Clercq

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

Factors affecting ease of ring formation : the effect of anchoring substitution on the rate of an intramolecular diels-alder reaction with furan-diene

Serge CauwberghsPierre De Clercq

A1 Journal Article in TETRAHEDRON LETTERS

Intramolecular diels-alder reaction with furan-diene : comparison of reactivity and stereoselectivity within a set of structurally related substrates of potential use in gibberellin total synthesis

G AppendinoJ HoflackPierre De ClercqG ChiariM Calleri

A1 Journal Article in TETRAHEDRON

The effect of anchoring substitution on the course of a cation olefin bicyclization : crystal structure of (+/-)-(2R,3'R,5'S)-2-(3'-tert-butyl-5'-isopropyl-5'-methyl-1'-cyclopentenyl)-1-cyclopentanone

Patrick MissiaenPierre De ClercqLuc Van MeerveltGeoffrey SD King

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

The SCA program : an easy way for the conformational evaluation of polycyclic molecules

J HoflackPierre De Clercq

A1 Journal Article in TETRAHEDRON

1987

An unsuccessful route to C-8 oxygenated pseudoguaianolides : X-ray diffraction study of 4,9-dimethyl-13-methoxycarbonyl-8-trifluoroacetoxy-11-oxatetracyclo|8.3. 0<sup>2,13<\sup>.0<sup>5,9<\sup>|tridecan-12-one (1β,2β,4β,5α,8α,9β,10β,13β)

B TinantJP DeclercqM van MeersscheP KokG RozingF ScottM DemuynckND SinhaPierre De ClercqMaurits Vandewalle

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

Intramolecular Diels-Alder reaction with furan-diene : activated allene as dienophile in BCD-ring approach to steroids

P MissiaenPierre De Clercq

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

L-(S)-erythrulose : a novel precursor to L-2,3-O-isopropylidene-C3 chirons

Hester De WildePierre De ClercqMaurits VandewalleHarald Röper

A1 Journal Article in TETRAHEDRON LETTERS

Total synthesis of natural products via intramolecular Diels-Alder reaction with furan-diene and allene-dienophile

Pierre De ClercqSerge Cauwberghs

Total synthesis of natural products via intramolecular Diels-Alder reaction with furan-diene and allene-dienophile

Pierre De ClercqSerge Cauwberghs

1986

A novel expeditious entry into gibberellins : the total synthesis of (±)-GA5

WN GrootaertPierre De Clercq

A1 Journal Article in TETRAHEDRON LETTERS

Total synthesis of (±)-podophyllotoxin and (±)-epipodophyllotoxin

Johan Van der EyckenPierre De ClercqMaurits Vandewalle

A1 Journal Article in TETRAHEDRON

Total synthesis of podophyllum lignans : an exploratory study

Johan Van der EyckenPierre De ClercqMaurits Vandewalle

A1 Journal Article in TETRAHEDRON

1985

An efficient synthesis of 1α,25-dihydroxy vitamin D3

LJ VanmaelePierre De ClercqMaurits Vandewalle

A1 Journal Article in TETRAHEDRON

Intramolecular Diels-Alder reaction with furan-diene : total synthesis of (±)-11-ketotesterone and (±)-adrenosterone

LA Van RoyenR MijngheerPierre De Clercq

A1 Journal Article in TETRAHEDRON

Reacties bij lage temperatuur : nieuwe perspectieven in organische synthese

Pierre De Clercq

A4 Journal Article in CHEMIE MAGAZINE (LEIDSCHENDAM)

Synthesis of hexadeuterated hexestrol (R,S)-3,4-di-(4-hydroxyphenyl)hexane-1,1,1,6,6,6-2H(6)

Pierre De ClercqJM HoflackLA Van RoyenCarlos Van Peteghem

A1 Journal Article in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Total synthesis of (±)-podophyllotoxin and (±)-epipodophyllotoxin

Johan Van der EyckenPierre De ClercqMaurits Vandewalle

A1 Journal Article in TETRAHEDRON LETTERS

Total synthesis of polycarbocyclic sesquiterpenes : a survey of novel methods and reactions

Maurits VandewallePierre De Clercq

A1 Journal Article in TETRAHEDRON

1984

1α-hydroxy previtamin D3, and its selective formation from 1-keto previtamin D3

LJ VanmaelePierre De ClercqMaurits VandewalleSJ HalkesWRM Overbeek

A1 Journal Article in TETRAHEDRON

Intramolecular Diels-Alder reaction with furan-diene : 1. A novel entry to the BCD-ring system of 11-ketosteroids

LA van RoyenR MijngheerPierre De Clercq

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

Synthesis of hexadeuterated diethylstilbestrol (E-3,4-di-(4-hydroxyphenyl)hex-3-ene-1,1,1,6,6,6-2H(6))

Pierre De ClercqCarlos Van PeteghemJA JonckheereAndreas De Leenheer

A1 Journal Article in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Systematic conformational analysis : a microcomputer method for the semiquantitative evaluation of polycyclic systems containing five-, six- and seven-membered rings : 1. Program characteristics

Pierre De Clercq

A1 Journal Article in TETRAHEDRON

Systematic conformational analysis : a microcomputer method for the semiquantitative evaluation of polycyclic systems containing five-, six- and seven-membered rings : 2. Scope and limitations

Pierre De Clercq

A1 Journal Article in TETRAHEDRON

X-ray diffraction study of (±)-5α- [2′-hydroxy-1'-methoxycarbonyl-2'-(3″,4″,5″-trimethoxyphenyl) ethyl)-4α-(3″'-4″'-methylenedioxyphenyl)-2α-phenyl-1,3-dioxane

C Piccinni-LeopardiJP DeclercqG GermainM van MeersscheJohan Van der EyckenPierre De ClercqMaurits Vandewalle

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

1983

Guaianolides 1. perhydroazulenic lactones as intermediates for total synthesis

AA DevreeseM DemuynckPierre De ClercqMaurits Vandewalle

A1 Journal Article in TETRAHEDRON

Guaianolides : 2. total synthesis of (±)-compressanolide and (±)-estafiatin

AA DevreeseM DemuynckPierre De ClercqMaurits Vandewalle

A1 Journal Article in TETRAHEDRON

Intramolecular Diels-Alder reaction with furan diene : a new synthesis of 11-keto steroids

LA Van RoyenR MijngheerPierre De Clercq

A1 Journal Article in TETRAHEDRON LETTERS

Intramolecular electrophilic substitution of vinylsilane : an electronic disfavored reaction course

J HoflacklaPierre De Clercq

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

Remote-controlled production of 11C-antipyrine

Dirk Van HaverPierre De ClercqMaurits VandewalleTony VandewalleCarlo Vandecasteele

X-ray diffraction study of 5-hydroxy-6-methyl-14-oxatetracyclo|7.4.1(1,11).0(2,6)|tetradecan-8-one (1α, 2α, 5β, 6β, 9β,11α)

M van MeersscheJP DeclercqLA van RoyenPierre De Clercq

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

1982

A novel synthesis of 1(S)-hydroxyvitamin D3

Luc VanmaelePierre De ClercqMaurits Vandewalle

A novel synthesis of 1-α-hydroxyvitamin D3

Maurits VandewallePierre De ClercqLuc Vanmaele

A novel synthesis of 1-α-hydroxyvitamin D3

Maurits VandewallePierre De ClercqLuc Vanmaele

A novel sythesis of 1(S)-hydroxyvitamin D3

L. VanmaelePierre De ClercqMaurits Vandewalle

A stereocontrolled partial synthesis of 1α-hydroxy vitamin D3

LJ VanmaelePierre De ClercqMaurits Vandewalle

A1 Journal Article in TETRAHEDRON LETTERS

Guaianolides : the total synthesis of (±)-estafiantin

M DemuynckAA DevreesePierre De ClercqMaurits Vandewalle

A1 Journal Article in TETRAHEDRON LETTERS

Intramolecular Diels-Alder reaction with furan-diene : a novel potential entry to steroids

LA Van RoyenR MijngheerPierre De Clercq

A1 Journal Article in TETRAHEDRON LETTERS

Intramolecular Diels-Alder reaction with furan-diene : an expeditious entry into a functionalized gibbane

WM GrootaertPierre De Clercq

A1 Journal Article in TETRAHEDRON LETTERS

Remote-controlled production of [11C]antipyrine

Dirk Van HaverPierre De ClercqT Van de WalleC Vandecasteele

A1 Journal Article in INTERNATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES

Retroaldol-aldol isomerization of perhydroazulenic hydroxyketones

P KokND SinhaPatrick SandraPierre De ClercqMaurits Vandewalle

A1 Journal Article in TETRAHEDRON

Synthesis of 1-α-hydroxycholecalciferol

Maurits VandewallePierre De ClercqLuc Vanmaele

Synthesis of 3-carbomethoxy-3,4-dialkylcyclohexanones

WM GrootaertR MijngheerPierre De Clercq

A1 Journal Article in TETRAHEDRON LETTERS

X-ray diffraction study of 2,4a,4b,5,6,7,8,9,9a,10-decahydro-7,10-dihydroxy-2,4a-epoxy-8-methylene-7,9a-methanobenz|a|azulene-1-carboxylic acid ethyl ester (2α,4aα,4bβ,7β,9aα,10β)

M van MeersscheJP DeclercqWM GrootaertPierre De Clercq

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

X-ray diffraction study of the Diels-Alder adduct of 4-phenyl-1,2,4-triazoline-3,5-dione with previtamin D3

M Van MeersscheB TinantG GermainJP DeclercqLJ VanmaelePierre De ClercqMaurits Vandewalle

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

1981

(±)-Decahydro-9-hydroxy-9-methylspiro[azuleno[4,5-b]furan-6(2H),2'-[1, 3]dioxolan]-2-one (3aα, 6aα, 9α, 9aα, 9bβ)

JP DeclercqG GermainM Van MeersscheA DevreesePierre De ClercqMaurits Vandewalle

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

Computergeassisteerde organische synthese

Pierre De Clercq

A4 Journal Article in CM CHEMIE MAGAZINE

Systematic conformational analysis : general method for rapid conformational evaluation : its application to the hydroazulene system

Pierre De Clercq

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

Systematic conformational analysis : torsion constraint evaluation in cyclic systems

Pierre De Clercq

A1 Journal Article in TETRAHEDRON

Totaalsynthese van sesquiterpeenlactonen : een efficiënte route tot guaianolieden

André DevreesePierre De ClercqMaurits Vandewalle

A4 Journal Article in V.C.V. TIJDINGEN

X-ray diffraction study of (±)-decahydro-9-hydroxy-9-methylspiro|azuleno|4,5-b|furan-6 (2h), 2'-|1,3|dioxolan|-2-one (3aβ,6aα,9β,9aβ,9bα)

JP DeclercqG GermainM Van MeersscheA De VreesePierre De ClercqMaurits Vandewalle

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

1980

(±)-Decahydro-4,5-dihydroxy-4a,8-dimethylazuleno[6,5-b]furan-2(3H)-one , (3aα,4α,4aβ,5α,7aα,8α,9aβ)

JP DeclercqG GermainM Van MeersscheP KokPierre De ClercqMaurits Vandewalle

A1 Journal Article in ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE

(±)-Decahydro-4-hydroxy-4a,8-dimethylazuleno[6,5-b]furan-2,5(3H)-dione (3aα, 4α, 4aβ, 7aα, 8α, 9aβ)

JP DeclercqG GermainM Van MeersscheP KokPierre De ClercqMaurits Vandewalle

A1 Journal Article in ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE

A general entry to guaianolides : an illustrative synthesis of (±)-compressanolide

AA DevreesePierre De ClercqMaurits Vandewalle

A1 Journal Article in TETRAHEDRON LETTERS

Configurational assignment and 1H NMR spectral parameters of isomeric 1,2-diacetoxy-4-alkyl-3-methylcyclopentanes

R HanselaerPierre De Clercq

A1 Journal Article in ORGANIC MAGNETIC RESONANCE

JP DeclercqG GermainM Van MeersscheM DemuynckPierre De ClercqMaurits Vandewalle

A1 Journal Article in ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE

Total synthesis of sesquiterpene lactones : an efficient entry to guaianolides

André DevreesePierre De ClercqMaurits Vandewalle

Total synthesis of sesquiterpene lactones : an efficient route to guaianolides

Maurits VandewallePierre De ClercqAndré Devreese

1979

(+/-)-Hysterin : revised structure and total synthesis

M DemuynckPierre De ClercqMaurits Vandewalle

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

(±)-Carpesiolin : total synthesis and structural determination

P KokPierre De ClercqMaurits Vandewalle

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

Pseudoguaianolides : a stereoselective approach to 8(α)-oxygenated helenanolides : X-ray structural determination of a synthetic intermediate

P KokPierre De ClercqMaurits VandewalleJP DeclercqG GermainM Van Meerssche

A1 Journal Article in TETRAHEDRON LETTERS

Sesquiterpene lactones : a total synthesis of (+/-)vernolepin

Freddy ZuttermanH. De WildeRoelant MijngheerPierre De ClercqMaurits Vandewalle

A1 Journal Article in TETRAHEDRON

The intramolecular Diels-Alder furan approach in synthesis : 11-oxatricyclo|6.2.1.0 1,6 |undec-9-en-5-one

Pierre De ClercqLuc A. Van Royen

A1 Journal Article in SYNTHETIC COMMUNICATIONS

1978

Pseudoguaianolides : the total synthesis of (±)-neoambrosin (±)-parthenin and (±)-hymenin

Pierre KokPierre De ClercqMaurits Vandewalle

A1 Journal Article in BULLETIN DES SOCIÉTÉS CHIMIQUES BELGES

Synthesis of pseudoguaianolides : a study for the stereocontrol at the 2-position

G. P. ROZINGPierre De ClercqMaurits Vandewalle

A2 Journal Article in SYNTHESIS

The conformation and configurational assignment of 6,7-disubstituted 2-oxybicylco[3.3.0]octan-3-ones

Pierre De ClercqMG Samson

A1 Journal Article in ORGANIC MAGNETIC RESONANCE

The total synthesis of fragrant compounds from jasmine oil

Pierre De ClercqR Mijngheer

A1 Journal Article in BULLETIN DES SOCIETES CHIMIQUES BELGES

The total synthesis of pseudoguaianolides

Maurits VandewallePierre De ClercqMarc DemuynckPierre KokGerard RozingFrederick Scott

1977

A novel entry to substituted hydroazulenes

D TermontPierre De ClercqD De KeukeleireMaurits Vandewalle

A1 Journal Article in SYNTHESIS-STUTTGART

A novel synthesis of the cis-fused 2-oxA-3-decalone system present in vernolepin

F ZuttermanPierre De ClercqMaurits Vandewalle

A1 Journal Article in TETRAHEDRON LETTERS

A stereo controlled route to a key intermediate for the synthesis of maytansine

M SamsonPierre De ClercqH De WildeMaurits Vandewalle

A1 Journal Article in TETRAHEDRON LETTERS

Configurational assignment of some isomeric 1,4-diacetoxy-2,3-dialkylcyclopentanes from 1H-n.m.r. spectral parameters

Pierre De ClercqM Samson

A1 Journal Article in ORGANIC MAGNETIC RESONANCE

Conformational analysis of prostaglandins F1 based on proton nuclear magnetic resonance spectral data

Pierre De ClercqM SamsonDirk TavernierDirk Van HaverMaurits Vandewalle

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

Cyclopentanones : XVIII : The lithium-liquid ammonia reduction of some 2,3-dialkyl-(4-hydroxy)-2-cyclopentenones : the importance of protonation of intermediate enolate anions on the stereochemical outcome

M SamsonPierre De ClercqMaurits Vandewalle

A1 Journal Article in TETRAHEDRON

Total synthesis of (+/-)-damsin

Pierre De ClercqMaurits Vandewalle

A1 Journal Article in JOURNAL OF ORGANIC CHEMISTRY

1976

1H-NMR spectral parameters of some 1,4-dihydroxy-2,3-dialkylcyclopentanes : the configurational dependent magnitude of some 1H-NMR spectral parameters

Pierre De ClercqM. Samson

A1 Journal Article in BULLETIN DES SOCIÉTÉS CHIMIQUES BELGES

Cyclopentanones : XVI : Prostaglandin synthesis involving catalytic hydrogenation of 2,3-dialkyl-4-hydroxy-2-cyclopentenones

Pierre De ClercqR. CoenE Van HoofMaurits Vandewalle

A1 Journal Article in TETRAHEDRON

1975

Cyclopentanones : XII. An alternative synthesis of prostaglandins involving catalytic hydrogenation of 2, 3-dialkyl-4-dihydroxy-2-cyclopentenones

R. CoenPierre De ClercqDirk Van HaverMaurits Vandewalle

A1 Journal Article in BULLETIN DES SOCIÉTÉS CHIMIQUES BELGES

Cyclopentanones : XIII : The proton donor depending stereoselectivity of lithium ammonia reduction of 2,3-dimethyl-4-hydroxy-2-cyclopentenone

M SamsonPierre De ClercqMaurits Vandewalle

A1 Journal Article in TETRAHEDRON

1974

Cyclopentanones : X. A novel synthesis of (dl)-prostaglandin F1α

Pierre De ClercqMaurits Vandewalle

A1 Journal Article in BULLETIN DES SOCIÉTÉS CHIMIQUES BELGES

Cyclopentanones : XI. A novel preparation of a prostanoid synthon starting from a 3-alkyl-1,2,4-cyclopentanetrione

J. Van HoolandPierre De ClercqMaurits Vandewalle

A1 Journal Article in TETRAHEDRON LETTERS

Cyclopentanones—VIII : stereochemistry of the lithium-liquid ammonia reduction of 2,3-dialkyl-4-hydroxy-2-cyclopentenones

Pierre De ClercqDirk Van HaverDirk TavernierM Vandewalle

A1 Journal Article in TETRAHEDRON

Studies in organic mass spectrometry : XX. Stereospecificity in hydrogen transfer reactions in mass spectra of TMS derivatives of some 2,3-dialkyl-1, 4-cyclopentanediols

M. Maenhaut-ClaeysPierre De ClercqMaurits Vandewalle

A1 Journal Article in ORGANIC MASS SPECTROMETRY