Research Explorer

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Researcher

Philippe Van Rompaey

Awards & Distinctions

14 Results

2006

Orthogonal activation of the reengineered A(3) adenosine receptor (neoceptor) using tailored nucleoside agonists

ZG GAOHT DUONGT SONINASK KIMPhilippe Van RompaeySerge Van CalenberghL MAMEDOVAHO KIMMJ KIMAY KIM et al.

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

2005

Exploring human adenosine A₃ receptor complementarity and activity for adenosine analogues modified in the ribose and purine moiety

Philippe Van RompaeyKenneth A JacobsonAriel S GrossZhan-Guo GaoSerge Van Calenbergh

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

2004

Modulation of adenosine receptor affinity and intrinsic efficacy in adenine nucleosides substituted at the 2-position

M OHNOZG GAOPhilippe Van RompaeyS TCHILIBONSK KIMBA HARRISAS GROSSHT DUONGSerge Van CalenberghKA JACOBSON

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

Neoceptor concept applied to human A2A and A3 adenosine receptors.

KA JACOBSONSK KIMM OHNOHT DUONGPhilippe Van RompaeySerge Van CalenberghZG GAO

Synthesis and Biological Evaluation of Modified Adenosine and Thymidine Nucleoside Analogues

Philippe Van RompaeyS Van Calenbergh

2003

Design of a neoceptor and complementary neoligand derived from the A2A adenosine receptor.

SK KIMZG GAOPhilippe Van RompaeyAS GROSSAS CHENSerge Van CalenberghKA JACOBSON

Modeling the adenosine receptors: Comparison of the binding domains of A(2A) agonists and antagonists

SK KIMZG GAOPhilippe Van RompaeyAS GROSSA CHENSerge Van CalenberghKA JACOBSON

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY

Mycobacterium tuberculosis thymidine monophosphate kinase inhibitors: Biological evaluation and conformational analysis of 2 '- and 3 '-modified thymidine analogues

Philippe Van RompaeyK NAUWELAERTSVeerle VanheusdenJ ROZENSKIH MUNIER-LEHMANNP HERDEWIJNSerge Van Calenbergh

A1 Journal Article in EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Presence of N,N-Dimethyl-3,4-Methylenedioxyamphetamine(MDDM) in a fatal MDMA-overdose

M BOUCHEEls De LetterSofie Vande CasteelePhilippe Van RompaeyMichel PietteJan Van Bocxlaer

Thymidine and thymidine-5 '-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase

Veerle VanheusdenPhilippe Van RompaeyH MUNIER-LEHMANNS POCHETP HERDEWIJNSerge Van Calenbergh

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

2002

Amine-modified nucleosides as adenosine A(3) neoceptor ligands

Philippe Van RompaeyK JACOBSONZ GAOA CHEND BARAKS KIMKyooyoung LeeA LINKB LIANGPiet Herdewijn et al.

Chemotaxonomic features associated with flavonoids of cannabinoid-free cannabis (Cannabis sativa subsp sativa L.) in relation to hops (Humulus lupulus L.).

Gerd VanhoenackerPhilippe Van RompaeyDenis De KeukeleirePatrick Sandra

A1 Journal Article in NATURAL PRODUCT LETTERS

Thymidine (monophosphate) analogues as Mycobacterium tuberculosis thymidylate kinase inhibitors

Philippe Van RompaeyV VEERLES POCHETH MUNIER-LEHMANNM FROEYENPiet HerdewijnSerge Van Calenbergh

2001

Neoceptor concept based on molecular complementarity in GPCRs: A mutant adenosine A(3) receptor with selectively enhanced affinity for amine-modified nucleosides.

KA JACOBSONZG GAOAS CHEND BARAKSA KIMK LEEA LINKPhilippe Van RompaeySerge Van CalenberghBT LIANG

A1 Journal Article in JOURNAL OF MEDICINAL CHEMISTRY