Research Explorer

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Researcher

Philippe De Groote

14 Results

2022

A method for the purification of non-pyrogenic bacteriophage derived endolysins with an in vitro or in vivo application

Niels Vander ElstVincent De MaesschalckPhilippe De GrooteEvelyne MeyerRob LavigneYves Briers

Combinatorial assembly and optimisation of designer cellulosomes : a galactomannan case study

Julie VanderstraetenMaria João de Carvalho Maurício da FonsecaPhilippe De GrooteDennis GrimonHans GerstmansAmaranta KahnSarah MoraïsEdward A. BayerYves Briers

A1 Journal Article in BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS

Conversion of the free Cellvibrio japonicus xyloglucan degradation system to the cellulosomal mode

Julie VanderstraetenBabette LamoteMaria João de Carvalho Maurício da FonsecaPhilippe De GrooteYves Briers

A1 Journal Article in APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Hacking yeast cells with phage lysins to win the fight against antibiotic resistant bacteria

Emma CremeliePhilippe De GrooteBabette LamoteYves Briers

2018

Keratinocyte-Specific Ablation of RIPK4 Allows Epidermal Cornification but Impairs Skin Barrier Formation

Corinne UrwylerGiel TangheKirsten LeursBarbara GilbertRiet De RyckeMichiel De BruyneSaskia LippensSona BartunkovaPhilippe De GrooteCarien Niessen et al.

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

RIPK4 activity in keratinocytes is controlled by the SCFβ-TrCP ubiquitin ligase to maintain cortical actin organization

Giel TangheCorinne UrwylerPhilippe De GrooteEmmanuel DejardinPieter-Jan De BockKris GevaertPeter VandenabeeleWim Declercq

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

2016

Generation of a new Gateway-compatible inducible lentiviral vector platform allowing easy derivation of co-transduced cells

Philippe De GrooteSasker GrootjansSaskia LippensChantal EichpergerKirsten LeursIrene KahrGiel TangheInge BruggemanWouter De SchamphelaireCorinne Urwyler et al.

A1 Journal Article in BIOTECHNIQUES

Vaccination with necroptotic cancer cells induces efficient anti-tumor immunity

Tania Love AaesAgnieszka KaczmarekTinneke DelvaeyeBram De CraeneStefaan De KokerLiesbeth HeyndrickxIris DelrueJoachim TaminauBartosz WiernickiPhilippe De Groote et al.

A1 Journal Article in CELL REPORTS

2015

A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes

Philippe De GrooteHong Tran ThiMathias FransenGiel TangheCorinne UrwylerBram De CraeneKirsten LeursBarbara GilbertGriet Van ImschootRiet De Rycke et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

2013

CDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction point

Xavier BisteauSabine PaternotBianca ColleoniKarin EckerKatia CoulonvalPhilippe De GrooteWim DeclercqLudger HengstPierre P Roger

A1 Journal Article in PLOS GENETICS

Caspase-14 overexpression in hairless mice is not involved in utricle formation

Michael DevosPhilippe De GrooteBarbara GilbertInge BruggemanKirsten LeursSaskia LippensPeter VandenabeeleWim Declercq

A1 Journal Article in EXPERIMENTAL DERMATOLOGY

2012

Study of RIPK4 function in skin homeostasis and disease

Philippe De GrooteWim DeclercqSaskia LippensPeter Vandenabeele

2011

Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin

Esther HostePatrick KempermanMichael DevosGeertrui DeneckerSanja KezicNico YauBarbara GilbertSaskia LippensPhilippe De GrooteRia Roelandt et al.

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

2007

Generation of active recombinant human caspase-14

Philippe De GrootePetra OvaereEsther HosteGeertrui DeneckerSaskia LippensPeter VandenabeeleWim Declercq