Research Explorer

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Researcher

Peggy Jacques

Publications & Research Data

Awards & Distinctions

79 Results

2025

Endogenous lipoid pneumonia in adult autoinflammatory disease

Katrien SlabbynckJo Van DorpeIsabelle PeeneKarin MelsensCedric BosteelsRik JoosDirk ElewautPeggy JacquesHans SlabbynckGaëlle Varkas

A1 Journal Article in ARTHRITIS CARE & RESEARCH

2024

Longevity of the humoral and cellular responses after SARS-CoV-2 booster vaccinations in immunocompromised patients

Matthijs OyaertMarie-Angélique De ScheerderSophie Van HerrewegeGuy LaureysSofie Van AsscheMelissa CambronLeslie NaesensLevi HosteKarlien ClaesFilomeen Haerynck et al.

A1 Journal Article in EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Shared lung and joint T cell repertoire in early rheumatoid arthritis driven by cigarette smoking

Koen VenkenMatthias JarlborgFrederik StevenaertThomas MalfaitCarolien VliegheYann AbrahamTeddy ManuelloTine DecruyStijn VanheeHans Wils et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

What benefit–risk trade-offs are acceptable to rheumatoid arthritis patients during treatment selection? Evidence from a multicountry choice experiment

Rieke AltenJuan Carlos Nieto-GonzalezPeggy JacquesCarlomaurizio MontecuccoRobert MootsHelga RadnerHarald E VonkemanSebastian HeidenreichChiara WhichelloNicolas Krucien et al.

A1 Journal Article in RMD OPEN

2023

Distinct immune modulatory roles of regulatory T cells in gut versus joint inflammation in TNF-driven spondyloarthritis

Koen VenkenMatthias JarlborgTine DecruyCéline MortierCarolien VliegheElisabeth GilisAnn-Sophie De CraemerJulie CoudenysIsabelle CambréDevan Fleury et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Transport by circulating myeloid cells drives liposomal accumulation in inflamed synovium

Joke DeprezRein VerbekeSofie MeulewaeterIlke AernoutHeleen DewitteTine DecruyJulie CoudenysJulie Van DuyseGert Van IsterdaelDan Peer et al.

A1 Journal Article in NATURE NANOTECHNOLOGY

2022

Evaluation of humoral and cellular responses in SARS-CoV-2 mRNA vaccinated immunocompromised patients

Matthijs OyaertMarie-Angélique De ScheerderSophie Van HerrewegeGuy LaureysSofie Van AsscheMelissa CambronLeslie NaesensLevi HosteKarlien ClaesFilomeen Haerynck et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Evaluation of liposome-loaded microbubbles as a theranostic tool in a murine collagen-induced arthritis model

Joke DeprezSilke RooversGuillaume LajoinieHeleen DewitteTine DecruyJulie CoudenysBenedicte DescampsChristian VanhoveMichel VersluisDirk Elewaut et al.

A2 Journal Article in SCIENTIA PHARMACEUTICA

IgA rheumatoid factor in rheumatoid arthritis

Lieve Van HoovelsBert Vander CruyssenDaniela SieghartCarolien BonroyEszter NagyRille PulleritsSasa CucnikCharlotte DahleIngmar HeijnenLuca Bernasconi et al.

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Laser speckle contrast analysis in rheumatoid arthritis : a pilot study

Matthieu Vanden BulckeAmber VanhaeckeEllen DeschepperM CutoloPeggy JacquesVanessa Smith

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

Multicentre study to improve clinical interpretation of rheumatoid factor and anti-citrullinated protein/peptide antibodies test results

Lieve Van HoovelsBert Vander CruyssenDaniela SieghartCarolien BonroyEszter NagyRille PulleritsSasa CucnikCharlotte DahleIngmar HeijnenLuca Bernasconi et al.

A1 Journal Article in RMD OPEN

Standardisation of ACPA tests : evaluation of a new candidate reference preparation

Lieve Van HoovelsLucy StudholmeBert Vander CruyssenDaniela SieghartCarolien BonroyEszter NagyRille PulleritsSasa ČučnikCharlotte DahleIngmar Heijnen et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Work status in patients with inflammatory rheumatic musculoskeletal diseases : results of a Belgian comparative study

Ann-Sophie De CraemerIne DesimpeleLauren DelmezLiselotte DerooThomas RensonSophie De MitsVanessa SmithPeggy JacquesDirk ElewautPhilippe Carron et al.

2021

Efficacy of a tight-control and treat-to-target strategy in axial spondyloarthritis : results of the open-label, pragmatic, cluster-randomised TICOSPA trial

Anna MoltoClementina López-MedinaFilip Van den BoschAnnelies BoonenCasper WebersEmanuelle DernisFloris A van GaalenMartin SoubrierPascal ClaudepierreAthan Baillet et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Exploring novel drug delivery strategies in rheumatoid arthritis : nanomedicines and ultrasound triggered drug delivery

Joke DeprezStefaan De SmedtPeggy JacquesIne Lentacker

MRI-based synthetic CT in the detection of structural lesions in patients with suspected sacroiliitis : comparison with MRI

Lennart JansMin ChenDirk ElewautFilip Van den BoschPhilippe CarronPeggy JacquesRuth WittoekJacob L. JaremkoNele Herregods

A1 Journal Article in RADIOLOGY

2020

Blood-based test for diagnosis and functional subtyping of familial Mediterranean fever

Hanne Van GorpLinyan HuangPedro Henrique Viana SaavedraMarnik VuylstekeTomoko AsaokaGiusi PrencipeAntonella InsalacoBenson OgunjimiJerold JeyaratnamIlaria Cataldo et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Charting extracellular transcriptomes in the human biofluid RNA atlas

Eva HulstaertAnnelien MorlionFrancisco Avila CobosKimberly VerniersJustine NuytensEveline Vanden EyndeNurten YigitJasper AnckaertAnja GeertsPieter Hindryckx et al.

A1 Journal Article in CELL REPORTS

Cytokine profiling by multiplex immunoassay as a valuable tool for diagnosis and monitoring patients with autoinflammatory disorders

Levi HosteJo DehoornePeggy JacquesSteven CallensJeroen van der HilstVito SabatoBenson OgunjimiSimon TavernierFilomeen Haerynck

Pitfalls in the detection of myositis specific antibodies by lineblot in clinically suspected idiopathic inflammatory myopathy

Yves PietteMaxime De SloovereStien VandendriesscheJoke DehoorneJan De BleeckerLiesbet Van PraetAn-Sofie Vander MijnsbruggeSarah De SchepperPeggy JacquesFilip De Keyser et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

2019

Clinical features of axial spondyloarthritis patients diagnosed in peripheral versus an academic hospital

Ann-Sophie De CraemerThomas RensonPhilippe CarronPeggy JacquesJan LenaertsLieve GyselbrechtRik JoosFilip Van den BoschDirk Elewaut[missing] Be-Giant consortium

Response to: 'The use of dual-energy CT to detect and depict bone marrow oedema in rheumatoid arthritis: is it ready to substitute MRI?' by Wu et al.

Lennart JansIsabelle De KockNele HerregodsKoenraad VerstraeteFilip Van den BoschPhilippe CarronEdwin H OeiDirk ElewautPeggy Jacques

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients

Koen VenkenPeggy JacquesCéline MortierMark E. LabadiaTine DecruyJulie CoudenysKathleen HoytAnita L. WayneRobert HughesMichael Turner et al.

A1 Journal Article in NATURE COMMUNICATIONS

The human biofluid RNA atlas : expanding the liquid biopsy field beyond the blood stream

Eva HulstaertKimberly VerniersJustine NuytensEveline Vanden EyndeNurten YigitJasper AnckaertAnja GeertsPeggy JacquesGuy BrusselleTHIERRY DERVEAUX et al.

2018

Dual-energy CT : a new imaging modality for bone marrow oedema in rheumatoid arthritis

Lennart JansIsabelle De KockNele HerregodsKoenraad VerstraeteFilip Van den BoschPhilippe CarronEdwin H OeiDirk ElewautPeggy Jacques

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Effect of mechanical stress on magnetic resonance imaging of the sacroiliac joints : assessment of military recruits by magnetic resonance imaging study

Gaëlle VarkasManouk de HoogeThomas RensonSophie De MitsPhilippe CarronPeggy JacquesMuriel MorisGeert SouverijnsLennart JansDirk Elewaut et al.

A1 Journal Article in RHEUMATOLOGY

Mechanical strain determines the site-specific direction of inflammation and tissue damage in arthritis

Isabelle CambréDjoere GaublommeArne BurssensPeggy JacquesDirk ElewautR LoriesG SchettG KolliasAmélie De MuynckLeander Meuris et al.

Mechanical strain determines the site-specific direction of inflammation and tissue damage in arthritis

Isabelle CambréDorien GaublommeArne BurssensPeggy JacquesLeander MeurisStijn LambrechtShea CarterAmélie De MuynckNico CallewaertGeorge Kollias et al.

Mechanical strain determines the site-specific localization of inflammation and tissue damage in arthritis

Isabelle CambréDjoere GaublommeArne BurssensPeggy JacquesNadia SchryversAmélie De MuynckLeander MeurisStijn LambrechtShea CarterPieter De Bleser et al.

A1 Journal Article in NATURE COMMUNICATIONS

2017

A20 inhibition of STAT1 expression in myeloid cells : a novel endogenous regulatory mechanism preventing development of enthesitis

Katelijne De WildeArne MartensStijn LambrechtPeggy JacquesMichael DrennanKarlijn DebusschereSrinath GovindarajanJulie CoudenysEveline VerheugenFien Windels et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Burden of hepatitis E virus infection in patients with rheumatic diseases

Peggy JacquesElizaveta PadalkoEveline VerheugenLien CattoirXavier VerhelstE NysS Van GuchtV HutseV SuinDirk Elewaut

Presence of bone marrow edema and structural lesions on magnetic resonance imaging of the sacroiliac joints in young military recruits before and after 6 weeks of intensive physical training

Gaëlle VarkasManouk de HoogeThomas RensonSophie De MitsPhilippe CarronPeggy JacquesMuriel MorisGeert SouverijnsLennart JansDirk Elewaut et al.

2015

Application of µCT in arthritis and osteoporosis research

Els LouagieIsabelle CambréAmélie De MuynckDjoere GaublommeElin PauwelsPieter VanderniepenFien WindelsJulie CoudenysNadia SchryversEveline Verheugen et al.

Integrating the pathogenesis of spondyloarthritis: gut and joint united?

Katelijne De WildeKarlijn DebusschereSam BeeckmanPeggy JacquesDirk Elewaut

A1 Journal Article in CURRENT OPINION IN RHEUMATOLOGY

2014

A bidirectional crosstalk between iNKT cells and adipocytes mediated by leptin modulates susceptibility for T cell mediated hepatitis

Koen VenkenSylvie SeeuwsLennart ZabeauPeggy JacquesTine DecruyJulie CoudenysEveline VerheugenFien WindelsDominiek CatteeuwMichael Drennan et al.

A1 Journal Article in JOURNAL OF HEPATOLOGY

Degree of bone marrow oedema in sacroiliac joints of patients with axial spondyloarthritis is linked to gut inflammation and male sex: results from the GIANT cohort

Liesbet Van PraetLennart JansPhilippe CarronPeggy JacquesELIEN GLORIEUSRoos ColmanHeleen CypersHerman MielantsMartine De VosClaude Cuvelier et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Gut inflammation in SpA: flagellin joins the dance?

Peggy JacquesDirk Elewaut

Editorial material

Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis

Lieselotte Vande WalleNina Van OpdenboschPeggy JacquesAmelie FossoulEveline VerheugenPeter VogelRudi BeyaertDirk ElewautThirumala-Devi KannegantiGeert van Loo et al.

A1 Journal Article in NATURE

Proof of concept: enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells

Peggy JacquesStijn LambrechtEveline VerheugenElin PauwelsGeorge KolliasMaria ArmakaMarleen VerhoyeAnnemie Van der LindenEric AchtenRik J Lories et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

The role of mechanical stress in the pathogenesis of spondyloarthritis and how to combat it

Peggy JacquesDennis McGonagle

A1 Journal Article in BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

2013

Emerging therapies for rheumatoid arthritis

Peggy JacquesFilip Van den Bosch

A1 Journal Article in EXPERT OPINION ON EMERGING DRUGS

From immune senescence and insulin resistance to obesity and sarcopenia: iNKT cell as bridge?

Anton De SpiegeleerDirk ElewautPeggy JacquesGertjan De FlouNele Van Den Noortgate

Microscopic gut inflammation in axial spondyloarthritis: a multiparametric predictive model

Liesbet Van PraetFilip Van den BoschPeggy JacquesPhilippe CarronLennart JansRoos ColmanELIEN GLORIEUSHarald PeetersHerman MielantsMartine De Vos et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

2012

Pathophysiology and role of the gastrointestinal system in spondyloarthritides

Peggy JacquesLiesbet Van PraetPhilippe CarronFilip Van den BoschDirk Elewaut

A1 Journal Article in RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Synovial fluid derived iNKT cells in chronic arthritides show an increased PROGRAMMED DEATH-1 expression and anergic phenotype

Koen VenkenLode MelisPeggy JacquesLiesbet Van PraetFilip Van den BoschDirk Elewaut

The transition of acute to chronic bowel inflammation in spondyloarthritis

Liesbet Van PraetPeggy JacquesFilip Van den BoschDirk Elewaut

A1 Journal Article in NATURE REVIEWS RHEUMATOLOGY

Therapy for spondyloarthritis : the role of extra-articular manifestations (eye, skin)

Philippe CarronLiesbet Van PraetPeggy JacquesDirk ElewautFilip Van den Bosch

A1 Journal Article in RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Tumor necrosis factor α-induced proteins: natural brakes on inflammation

Peggy JacquesDirk Elewaut

Editorial material

2011

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

Mourad MatmatiPeggy JacquesJonathan MaelfaitEveline VerheugenMirjam KoolMozes SzeLies GeboesEls LouagieConor Mc GuireLars Vereecke et al.

A1 Journal Article in NATURE GENETICS

A20 (TNFAIP3) deficiency in myeloid cells triggers rheumatoid arthritis

Dirk ElewautMourad MatmatiPeggy JacquesJonathan MaelfaitEveline VerheugenMirjam KoolMozes SzeLies GeboesEls LouagieConor Mc Guire et al.

An anti-inflammatory selective glucocorticoid receptor modulator preserves osteoblast differentiation

Alexander RauchValerie GossyeDebby BrackeElien GevaertPeggy JacquesKatrien Van BenedenBERNARD VANDOORENMartina RaunerLorenz C HofbauerGuy Haegeman et al.

A1 Journal Article in FASEB JOURNAL

Disruption of the SapM locus in Mycobacterium bovis BCG improves its protective efficacy as a vaccine against M. tuberculosis

Nele FestjensPieter BogaertAnjana BatniErica HouthuysEvelyn PletsDieter VanderschaegheBram LaukensBob AsselberghEef ParthoensRiet De Rycke et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

Mechanisms regulating TNF-driven gut and joint inflammation

Dirk ElewautPeggy JacquesLode MelisKoen Venken

A1 Journal Article in Advances in Experimental Medicine and Biology

Optimized alkylated cyclodextrin polysulphates with reduced risks on thromboembolic accidents improve osteoarthritic chondrocyte metabolism

Sara GroeneboerStijn LambrechtAad DhollanderPeggy JacquesBert Vander CruyssenRik J LoriesKatrien DevreeseKoen ChiersDirk ElewautAugust Verbruggen

A1 Journal Article in RHEUMATOLOGY

TNF driven activation of invariant NKT cells regulates combined gut and joint inflammation

Peggy JacquesSylvie SeeuwsHamida HammadBart LambrechtGeorge KolliasMartine De VosDirk Elewaut

2010

A multiparameter approach to monitor disease activity in collagen-induced arthritis

Sylvie SeeuwsPeggy JacquesJens Van PraetMichael DrennanNicky VandeghinsteReginald BrysDirk Elewaut

A multiparameter approach to monitor disease activity in collagen-induced arthritis

Sylvie SeeuwsPeggy JacquesJens Van PraetMichael DrennanJulie CoudenysTine DecruyEllen DeschepperLien LepescheuxPhilippe PujuguetLine Oste et al.

A1 Journal Article in ARTHRITIS RESEARCH & THERAPY

Biomechanical stretch is a key initiating event in the development of enthesitis in murine spondyloarthritis

Peggy JacquesStijn LambrechtEveline VerheugenRJ LoriesG KolliasAugust VerbruggenDirk Elewaut

Hydroxylase inhibition abrogates TNF-α-induced intestinal epithelial damage by hypoxia-inducible factor-1-dependent repression of FADD

Pieter HindryckxMartine De VosPeggy JacquesLiesbeth FerdinandeHarald PeetersKim OlievierSara BogaertBrigitta BrinkmanPeter VandenabeeleDirk Elewaut et al.

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Interactions between gut inflammation and arthritis/spondylitis

Peggy JacquesDirk ElewautHerman Mielants

A1 Journal Article in CURRENT OPINION IN RHEUMATOLOGY

Invariant natural killer T cells are natural regulators of murine spondylarthritis

Peggy JacquesKoen VenkenKatrien Van BenedenHamida HammadSylvie SeeuwsMichael DrennanDieter DeforceAugust VerbruggenMaria ApostolakiGeorge Kollias et al.

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Optimized alkylated cyclodextrin polysulphates restore osteoarthritic chondrocyte extracellular matrix metabolism

Sara GroeneboerStijn LambrechtAad DhollanderPeggy JacquesBert VandercruyssenKatrien DevreeseDirk ElewautAugust Verbruggen

Optimized alkylated cyclodextrin polysulphates restore osteoarthritic chondrocyte extracellular matrix metabolism

Sara GroeneboerStijn LambrechtAad DhollanderPeggy JacquesBert VandercruyssenKatrien DevreeseDirk ElewautAugust Verbruggen

Oxygen sensor inhibition attenuates TNF-α induced intestinal epithelial damage by hypoxia inducible factor (HIF) 1-dependent repression of fas-associated death domain protein (Fadd)

Pieter HindryckxMartine De VosPeggy JacquesLiesbeth FerdinandeHarald PeetersBrigitta BrinkmanPeter VandenabeeleDirk ElewautDebby Laukens

Systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondyloarthritis

Lode MelisBERNARD VANDOORENElli KruithofPeggy JacquesMartine De VosHerman MielantsAugust VerbruggenFilip De KeyserDirk Elewaut

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

2009

Reversible changes in serum immunoglobulin galactosylation during the immune response and treatment of inflammatory autoimmune arthritis

Katrien Van BenedenKen CoppietersW LaroyFilip De KeyserIlse HoffmanFilip Van den BoschBert Vander CruyssenMichael DrennanPeggy JacquesP Rottiers et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

Systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondyloarthritis

Lode MelisBERNARD VANDOORENElli KruithofPeggy JacquesMartine De VosHerman MielantsAugust VerbruggenFilip De KeyserDirk Elewaut

2008

Enhanced TNF-driven crosstalk to invariant NKT cells favours regulation of murine spondyloarthritis

Peggy JacquesKatrien Van BenedenSylvie SeeuwsMartine De VosDirk Elewaut

Joint expedition: linking gut inflammation to arthritis

Peggy JacquesDirk Elewaut

A1 Journal Article in Mucosal Immunology

Local and systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondyloarthritis

BERNARD VANDOORENLode MelisElli KruithofPeggy JacquesMartine De VosHerman MielantsAugust VerbruggenFilip De KeyserDirk Elewaut

Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases

Maria ARMAKAMaria APOSTOLAKIPeggy JacquesDimitris KONTOYIANNISDirk ElewautGeorge KOLLIAS

Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases

Maria ArmakaMaria ApostolakiPeggy JacquesDimitris KontoyiannisDirk ElewautGeorge Kollias

A1 Journal Article in Journal of Experimental Medicine

Spondyloarthropathies: progress and challenges

Peggy JacquesHerman MielantsMartine De VosDirk Elewaut

A1 Journal Article in Best Practice & Research in Clinical Rheumatology

2007

A comparison of TNF dependent and independent features of murine spondyloarthropathy

Peggy JacquesKen CoppietersKatrien Van BenedenHerman MietantsSylvie SeeuwsAugust VerbruggenMartine De VosDirk Elewaut

A single early activation of invariant NK T cells confers long-term protection against collagen-induced arthritis in a ligand-specific manner

Ken CoppietersKatrien Van BenedenPeggy JacquesPieter DewintAnn VervloetBert Vander CruyssenSerge Van CalenberghGuangwu ChenRichard FranckAugust Verbruggen et al.

A1 Journal Article in JOURNAL OF IMMUNOLOGY

NKT cells: manipulable managers of joint inflammation

Ken CoppietersPieter DewintKatrien Van BenedenPeggy JacquesSylvie SeeuwsAugust VerbruggenDieter DeforceDirk Elewaut

A1 Journal Article in RHEUMATOLOGY

The intimate relationship between gut and joint in spondyloarthropathies

Peggy JacquesHerman MielantsKen CoppietersMartine De VosDirk Elewaut

A1 Journal Article in CURRENT OPINION IN RHEUMATOLOGY

2006

Long-term IFN-gamma dependent efficacy of activated V alpha 14I natural killer T-cells in the prevention of collagen-induced arthritis

Ken CoppietersKatrien Van BenedenAnn VervloetPieter DewintPeggy JacquesSara GroeneboerMoriya TsujiAugust VerbruggenDieter DeforcePatrick Matthys et al.

Long-term IFN-gamma dependent efficacy of activated valpha141 natural killer T cells in the prevention of collagen-induced arthritis

Katrien Van BenedenKen CoppietersAnn VervloetB VandercruyssenPeggy JacquesPieter DewintB De KlerckH HeremansM TsujiG Verbruggen et al.