Research Explorer

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Researcher

Paul Ameloot

Awards & Distinctions

22 Results

2020

Off-target glycans encountered along the synthetic biology route toward humanized N-glycans in Pichia pastoris

Bram LaukensPieter JacobsKatelijne GheysenJosé MartinsCharlot De WachterPaul AmelootWilly MorelleJurgen HaustraeteJean-Christophe RenauldBart Samyn et al.

A1 Journal Article in BIOTECHNOLOGY AND BIOENGINEERING

2016

Elucidation of the molecular mechanisms of two nanobodies that inhibit thrombin‐activatable fibrinolysis inhibitor activation and activated thrombin‐activatable fibrinolysis inhibitor activity

X. ZhouS.D. WeeksPaul AmelootNico CallewaertS.V. StrelkovP.J. Declerck

A1 Journal Article in JOURNAL OF THROMBOSIS AND HAEMOSTASIS

2015

Efficacy of a trans-sialidase-ISCOMATRIX subunit vaccine candidate to protect against experimental Chagas disease

Iván Alejandro BontempiMiguel Hernán ViccoGabriel CabreraSilvina Raquel VillarFlorencia Belén GonzálezEduardo Angel RoggeroPaul AmelootNico CallewaertAna Rosa PérezIván Sergio Marcipar

A1 Journal Article in VACCINE

Production, purification and crystallization of a trans-sialidase from Trypanosoma vivax

Carole LF HaynesPaul AmelootHans RemautNico CallewaertYan G-J SterckxStefan Magez

A1 Journal Article in ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS

2013

Structure of Ostertagia ostertagi ASP-1: insights into disulfide-mediated cyclization and dimerization

Jimmy BorlooPeter GeldhofIris PeelaersFrederik Van MeulderPaul AmelootNico CallewaertJozef VercruysseEdwin ClaereboutSergei V StrelkovStephen D Weeks

A1 Journal Article in ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

2012

X-ray structure of Ostertagia ostertagi ASP-1 provides detailed insights in dimerization mechanism and protein cyclization

Jimmy BorlooPeter GeldhofIris PeelaersFrederik Van MeulderPaul AmelootNico CallewaertJozef VercruysseEdwin ClaereboutSergei StrelkovStephen D Weeks

2011

Vaccine testing of recombinant versions of the protective activation-associated secreted proteins from the bovine abomasal parasite Ostertagia ostertagi

Peter GeldhofPaul AmelootNico CallewaertJ PootJozef VercruysseEdwin Claerebout

2010

The HAC1 gene from Pichia pastoris: characterization and effect of its overexpression on the production of secreted, surface displayed and membrane proteins

Mouna GuerfalStefan RyckaertPieter JacobsPaul AmelootKathleen Van CraenenbroeckRiet De RyckeNico Callewaert

A1 Journal Article in MICROBIAL CELL FACTORIES

2007

Monoclonal antibodies reveal a weak interaction between the F18 fimbrial adhesin FedF and the major subunit FedA

Petra TielsFrank VerdonckAnnelies CoddensPaul AmelootBruno GoddeerisEric Cox

A1 Journal Article in VETERINARY MICROBIOLOGY

2006

An invertebrate TNF functional analogue activates macrophages via lectin-saccharide interaction with ion channels

M BILEJR JOSKOVAR VAN DEN BERGHP PROCHAZKOVAM SILEROVAPaul AmelootP DE BAETSELIERA BESCHIN

A1 Journal Article in INTERNATIONAL IMMUNOLOGY

2004

Production and characterization of receptor-specific TNF muteins

Paul AmelootPeter Brouckaert

A4 Journal Article in METHODS IN MOLECULAR MEDICINE

2002

Bioavailability of recombinant tumor necrosis factor determines its lethality in mice.

Paul AmelootNozomi TakahashiBart EveraerdtJeroen HostensHP EUGSTERWalter FiersPeter Brouckaert

A1 Journal Article in EUROPEAN JOURNAL OF IMMUNOLOGY

Characterization of the interaction between murine tumour necrosis factor and monoclonal antibodies.

Paul AmelootWalter FiersWA BUURMANP DE BAETSELIERPeter Brouckaert

A1 Journal Article in CYTOKINE

2001

Characterization of sialyltransferase mutants using surface plasmon resonance.

Wouter LaroyPaul AmelootRoland Contreras

A1 Journal Article in GLYCOBIOLOGY

Heterotrimers formed by tumor necrosis factors of different species or muteins.

Paul AmelootWim DeclercqWalter FiersPeter VandenabeelePeter Brouckaert

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of tumor necrosis factor (TNF) amino acids crucial for binding to the murine p75 TNF receptor and construction of receptor-selective mutants.

Paul AmelootWalter FiersPieter De BleserCF WAREPeter VandenabeelePeter Brouckaert

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

2000

Differential response of alpha(2)-macroglobulin-deficient mice in models of lethal TNF-induced inflammation.

Tino HochepiedPaul AmelootPeter BrouckaertF VAN LEUVENClaude Libert

A1 Journal Article in EUROPEAN CYTOKINE NETWORK

1998

Tumor necrosis factor-induced cytotoxicity is not related to rates of mitochondrial morphological abnormalities or autophagy-changes that can be mediated by TNFR-I or TNFR-II

JB PRINSEC LEDGERWOODPaul AmelootPeter VandenabeelePR FARACONA BRIGHTS O'RAHILLYJR BRADLEY

A1 Journal Article in BIOSCIENCE REPORTS

1996

Inhibition of and sensitization to the lethal effects of tumor necrosis factor

Peter BrouckaertClaude LibertAnje CauwelsBart EveraerdtWim Van MollePaul AmelootYannick GansemansBernardo GrijalbaNozomi TakahashiMarie-José Truong et al.

A1 Journal Article in JOURNAL OF INFLAMMATION

1994

Receptor-selective mutants of tumour necrosis factor in the therapy of cancer : preclinical studies

Peter BrouckaertPaul AmelootAnje CauwelsBart EveraerdtClaude LibertNozomi TakahashiWim Van MolleWalter Fiers

A1 Journal Article in CIRCULATORY SHOCK

1990

Funktionele analyse van het tabaksnekrose-satellietvirus genoom

Paul AmelootWalter Fiers

1987

Expression in plants of the cloned satellite tobacco necrosis virus genome and of derived insertion mutants

John Van EmmeloPaul AmelootWalter Fiers

A1 Journal Article in VIROLOGY