Research Explorer

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Researcher

Patrick Pauwels

Awards & Distinctions

46 Results

2018

Radiotherapy-activated cancer-associated fibroblasts promote tumor progression through paracrine IGF1R activation

Joke TommeleinElly De VlieghereLaurine VersetElodie MelsensJustine LeendersBenedicte DescampsAnnelies DebucquoyChristian VanhovePatrick PauwelsChristian P Gespach et al.

A1 Journal Article in CANCER RESEARCH

2013

Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling

Astrid De BoeckPatrick PauwelsKaren HensenJean-Luc RummensWendy WestbroekAn HendrixDawn MaynardHannelore DenysKathleen LambeinGeert Braems et al.

A1 Journal Article in GUT

Differential secretome analysis of cancer-associated fibroblasts and bone marrow-derived precursors to identify microenvironmental regulators of colon cancer progression

Astrid De BoeckAn HendrixDawn MaynardMieke Van BockstalAnnick DaniëlsPatrick PauwelsChristian GespachMarc BrackeOlivier De Wever

A1 Journal Article in PROTEOMICS

2012

An immunohistochemical analysis of Rab27B distribution in fetal and adult tissue

An HendrixKathleen LambeinWendy WestbroeckMiguel C SeabraVeronique CocquytPatrick PauwelsMarc BrackeChristian GespachOlivier De Wever

A1 Journal Article in INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Comparative analysis of dynamic cell viability, migration and invasion assessments by novel real-time technology and classic endpoint assays

Ridha LimameAn WoutersBea PauwelsErik FransenMarc PeetersFilip LardonOlivier De WeverPatrick Pauwels

A1 Journal Article in PLOS ONE

Single-photon emission computed tomographic imaging of the early time course of therapy-induced cell death using technetium 99m tricarbonyl His-annexin A5 in a colorectal cancer xenograft model

Christel VangestelChristophe Van De WieleGilles MeesKoen MertensSteven StaelensChris ReutelingspergerPatrick PauwelsNancy Van DammeMarc Peeters

A1 Journal Article in MOLECULAR IMAGING

2011

EGFR in melanoma : clinical significance and potential therapeutic target

Barbara BooneKoen JacobsLiesbeth FerdinandeJasmien TaildemanJo LambertMarc PeetersMarc BrackePatrick PauwelsLieve Brochez

A1 Journal Article in JOURNAL OF CUTANEOUS PATHOLOGY

Expression and prognostic value of glucose transporters and hexokinases in tonsil and mobile tongue squamous cell carcinoma

Philippe DeronHubert VermeerschGilles MeesChristel VangestelPatrick PauwelsChristophe Van De Wiele

A1 Journal Article in HISTOLOGY AND HISTOPATHOLOGY

MDM2 gene amplification and protein expressions in colon carcinoma: is targeting MDM2 a new therapeutic option?

Monirath HavLouis LibbrechtLiesbeth FerdinandePiet PattynStéphanie LaurentMarc PeetersMarleen PraetPatrick Pauwels

A1 Journal Article in VIRCHOWS ARCHIV

Metabolic correlates of tumour hypoxia in malignant canine mammary carcinoma

Gilles MeesChristel VangestelRudi DierckxSarah LoomansNathalie Van DammeKathelijne PeremansHilde De RoosterBart Van GoethemPatrick PauwelsRichard Ducatelle et al.

A1 Journal Article in RESEARCH IN VETERINARY SCIENCE

Relationship between pathological features, HER2 protein expression and HER2 and CEP17 copy number in breast cancer: biological and methodological considerations

Kathleen LambeinMarleen PraetRamses ForsythRudy Van den BroeckeGeert BraemsBART MATTHYSVeronique CocquytHannelore DenysPatrick PauwelsLouis Libbrecht

A1 Journal Article in JOURNAL OF CLINICAL PATHOLOGY

2010

Carbonic anhydrase IX expression correlates with FDG uptake by primary non-small cell lung cancer

Gilles MeesChristel VangestelRudi DierckxPatrick PauwelsJan Van MeerbeeckChristophe Van De Wiele

A1 Journal Article in CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Effect of the secretory small GTPase Rab27B on breast cancer growth, invasion, and metastasis

An HendrixDawn MaynardPatrick PauwelsGeert BraemsHannelore DenysRudy Van den BroeckeJo LambertSimon Van BelleVeronique CocquytChristian Gespach et al.

A1 Journal Article in JOURNAL OF THE NATIONAL CANCER INSTITUTE

Epidermal growth factor receptor and K-RAS status in two cohorts of squamous cell carcinomas

Nancy Van DammePhilippe DeronNadine Van RoyPieter DemetterAlain BolsJo Van DorpeFilip BaertJean-Luc Van LaethemFranki SpelemanPatrick Pauwels et al.

A1 Journal Article in BMC CANCER

The secretory GTPase RAB27b drives poor prognosis in ER alpha-positive breast cancer

An HendrixHannelore DenysGeert BraemsPatrick PauwelsRudy Van den BroeckeVeronique CocquytWendy WestbroekMarc BrackeOlivier De Wever

2009

Biomarkers ER, PR, HER-2 En topoisomerase II alpha in correlation with response to neoadjuvant chemotherapy for primary breast cancer

Kathleen LambeinPatrick PauwelsMICHIEL BUIJSROGGEHannelore DenysRudy Van den BroeckeHerman DepypereSimon Van BelleE DochyVeronique Cocquyt

Combined effect of EPO and radiotherapy on the expression of endogenous molecular markers of tumor metabolism and metastasis

Gilles MeesPhilippe FonteyneWim CeelenTom BoterbergPatrick PauwelsChristel VangestelNancy Van DammeMarc PeetersRudi DierckxChristophe Van De Wiele

A1 Journal Article in CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Epidermal growth factor receptor protein expression and gene amplification in Caucasian patients with malignant pleural mesothelioma (MPM)

Veerle SurmontMarleen PraetIsabelle RottiersELISABETH BEERENSBART MATTHYSPatrick PauwelsJan Van Meerbeeck

Expression of hexokinases and glucose transporters in treated and untreated oesophageal adenocarcinoma

Philippe FonteyneVeerle CasneufPatrick PauwelsNancy Van DammeMarc PeetersRudi DierckxChristophe Van De Wiele

A1 Journal Article in HISTOLOGY AND HISTOPATHOLOGY

MDM2 amplification in colorectal carcinomas

Stéphanie LaurentPiet PattynMarc PeetersPatrick Pauwels

Mdm2 in colon carcinoma: an immunohistochemical and fluorescence in situ hybridization study

Monirath HavLouis LibbrechtPiet PattynMarc PeetersMarleen PraetPatrick Pauwels

The extracellular matrix regulates cancer progression and therapy response: implications for prognosis and treatment

Hannelore DenysGeert BraemsKathleen LambeinPatrick PauwelsAn HendrixAstrid De BoeckVeronique MathieuMarc BrackeOlivier De Wever

A1 Journal Article in CURRENT PHARMACEUTICAL DESIGN

2008

Advances in the management of gastrointestinal stromal tumours

Sybile Van LierdeMarc PeetersNancy Van DammeKaren GeboesStéphanie LaurentISABEL DEROPatrick Pauwels

A2 Journal Article in BELGIAN JOURNAL OF MEDICAL ONCOLOGY

Differential impact of TGF-β and EGF on fibroblast differentiation and invasion reciprocally promotes colon cancer cell invasion

Hannelore DenysLara DeryckeAn HendrixWendy WestbroekAlexander GheldofKishan NarinePatrick PauwelsChristian GespachMarc BrackeOlivier De Wever

A1 Journal Article in CANCER LETTERS

Evaluation of EGFR and K-RAS gene status in squamous cell carcinoma of the anal canal.

Nancy Van DammeNadine Van RoyFranki SpelemanA BOLSJ VAN DORPEPatrick PauwelsMarc Peeters

Experience with FISH in melanocytic lesions

Patrick PauwelsRamses ForsythKathleen LambeinLieve BrochezBART MATTHYS

Expression of SGLT1 and Bcl-2 in pancreatic cancer and their metastases related to survival

Veerle CasneufNancy Van DammePatrick PauwelsPhilippe FonteyneBernard de HemptinneChristophe Van De WieleMarc Peeters

Expression of SGLT1 and Bcl-2 in panreatic cancer and their metastases related to survival.

Veerle CasneufNancy Van DammePhilippe FonteynePatrick PauwelsBernard de HemptinneChristophe Van De WieleMarc Peeters

Expression of SGLT1, Bcl-2 and p53 in primary pancreatic cancer related to survival

Veerle CasneufPhilippe FonteyneNancy Van DammePieter DemetterPatrick PauwelsBernard de HemptinneMartine De VosChristophe Van De WieleMarc Peeters

A1 Journal Article in CANCER INVESTIGATION

Expression of hexokinase II in pancreatic cancer predicts survival

Veerle CasneufPhilippe FonteyneNancy Van DammePatrick PauwelsBernard de HemptinneChristophe Van De WieleMarc Peeters

Gastrin releasing peptide receptor imaging in human breast carcinoma versus immunohistochemistry

Christophe Van De WielePhilippe FonteynePatrick PauwelsIngeborg GoethalsRudy Van den BroeckeVeronique CocquytRudi Dierckx

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

Investigation of the EGFR and K-RAS gene status in squamous cell carcinoma of the anal canal

Nancy Van DammeNadine Van RoyPieter DemetterFranki SpelemanA BolsJo Van DorpeN NagyJ Van LaethemPatrick PauwelsMarc Peeters

Molecular and pathological signatures of epithelial-mesenchymal transitions at the cancer invasion front

Olivier De WeverPatrick PauwelsBram De CraeneM SABBAHS EMAMIG REDEUILHC GESPACHMarc BrackeGeert Berx

A1 Journal Article in HISTOCHEMISTRY AND CELL BIOLOGY

Plexiform Angiomyxoid Myofibroblastic Tumor of the Stomach

Christine GalantEmmanuel RousseauDang Khanh Ho Minh DucPatrick Pauwels

A1 Journal Article in AMERICAN JOURNAL OF SURGICAL PATHOLOGY

2007

Absence of lymphangiogenesis in ductal breast cancer at the primary tumor site

DWJ VAN DER SCHAFTPatrick PauwelsS HULSMANSM ZIMMERMANNLV VAN DE POLL-FRANSEAW GRIFFIOEN

A1 Journal Article in CANCER LETTERS

Array CGH analysis in primary gastrointestinal stromal tumors: Cytogenetic profile correlates with Anatomic site and tumor aggressiveness, irrespective of mutational status

Artur WozniakR SCIOTL GUILLOUPatrick PauwelsB WASAGM STULJR VERMEESCHP VANDENBERGHEJ LIMONM DEBIEC-RYCHTER

A1 Journal Article in GENES CHROMOSOMES & CANCER

Detection of B-Catenin Gene Mutations in Paraffin-Embedded Sporadic Desmoid-Type Fibromatosis by Mutation-Specific Restriction Enzyme Digestion (MSRED): An Ancillary Diagnostic Tool

M AMARYB IDOWUL ISLAMK BOUSDRASPatrick PauwelsE MEULEMANST DISSA FLANAGAN

Detection of b-catenin gene mutations in paraffin-embedded sporadic desmoid-type fibromatosis by mutation-specific restriction enzyme digestion (MSRED): An ancillary diagnostic tool

MFC AMARYB IDOWUL ISLAMK BOUSDRASPatrick PauwelsE MEULEMANSTC DISSAM FLANAGAN

Detection of beta-catenin mutations in paraffin-embedded sporadic desmoid-type fibromatosis by mutation-specific restriction enzyme digestion (MSRED): An ancillary diagnostic tool

M FERNANDAC AMARYPatrick PauwelsE MEULEMANSGM ROEMENL ISLAMB IDOWUK BOUSDRASTC DISSP O'DONNELL et al.

A1 Journal Article in AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Differences in imiquimod treatment outcome in two patients with bowenoid papulosis containing either episomal or integrated human papillomavirus 16

Georges PH LuckerErnst-Jan M SpeelDavid CreytensAdrienne J van GeestJolanda HM PeetersSandra MH ClaessenAnton HM VermeulenPatrick PauwelsEls V Meulemans

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

Lymphangiogenesis in primary breast cancer - Reply

DWJ VAN DER SCHAFTALPatrick PauwelsS HULSMANSM ZIMMERMANNLV VAN DE POLL-FRANSEAW GRIFFIOEN

A1 Journal Article in CANCER LETTERS

Molecular analysis of primary gastric cancer, corresponding xenografts, and 2 novel gastric carcinoma cell lines reveals novel alterations in gastric carcinogenesis

ANA MILNER SITARZR CARVALHOMM POLAKM LIGTENBERGPatrick PauwelsGJA OFFERHAUSMAJ WETERMAN

A1 Journal Article in HUMAN PATHOLOGY

One-stage penectomy and phalloplasty for epithelioid sarcoma of the penis in an adolescent

Piet HoebekeSylvie RotteyNathalie Van HeddeghemGeert VilleirsPatrick PauwelsWILLY SCHRAUWENPeter CeulemansStan Monstrey

A1 Journal Article in EUROPEAN UROLOGY

Squamous cell carcinoma of the anus: a possible target for EGFR inhibition?

Marc PeetersJacques Van HuysseNancy Van DammeStéphanie LaurentISABEL DEROTom BoterbergPiet PattynPatrick Pauwels

2006

Differences in imiquimod treatment outcome in two patients with Bowenoid Papulosis containing either episomal or integrated HPV16

Els MeulemansErnst-Jan M SpeelGeorges PH LuckerDavid CreytensAdrienne Van GeestTon VermeulenSandra ClaessenPatrick Pauwels

Molecular pathogenesis of multiple gastrointestinal stromal tumors in NF1 patients

Ophélia MaertensH PRENENA WOZNIAKR SCIOTPatrick PauwelsI DE WEVERJR VERMEESCHT DE RAEDTAnne De PaepeFranki Speleman et al.

A1 Journal Article in HUMAN MOLECULAR GENETICS