Manage settings
MENU
About this site
In het Nederlands
Home
Researchers
Projects
Organisations
Publications
Infrastructure
Contact
Research Explorer
Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.
Researcher
Paco Hulpiau
Profile
Projects
Publications
Activities
Awards & Distinctions
42
Results
2023
Functions of the RIP kinase family members in the skin
Corinne Urwyler
Giel Tanghe
Michael Devos
Paco Hulpiau
Yvan Saeys
Wim Declercq
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2023
2022
Modifying PCDH19 levels affects cortical interneuron migration
Anna Pancho
Manuela D. D. Mitsogiannis
Tania Aerts
Marco Dalla Vecchia
Lena K. K. Ebert
Lieve Geenen
Lut Noterdaeme
Ria Vanlaer
Anne Stulens
Paco Hulpiau
et al.
A1
Journal Article
in
FRONTIERS IN NEUROSCIENCE
2022
2021
Characteristic ERK1/2 signaling dynamics distinguishes necroptosis from apoptosis
François Sipieter
Benjamin Cappe
Aymeric Leray
Elke De Schutter
Jolien Bridelance
Paco Hulpiau
Guy Van Camp
Wim Declercq
Laurent Heliot
Pierre Vincent
et al.
A1
Journal Article
in
ISCIENCE
2021
RyR2 regulates Cx43 hemichannel intracellular Ca2+-dependent activation in cardiomyocytes
Alessio Lissoni
Paco Hulpiau
Tânia Martins-Marques
Nan Wang
Geert Bultynck
Rainer Schulz
Katja Witschas
Henrique Girao
Maarten De Smet
Luc Leybaert
A1
Journal Article
in
CARDIOVASCULAR RESEARCH
2021
2020
Functional exploration of the GH29 fucosidase family
Hendrik Grootaert
Linde Van Landuyt
Paco Hulpiau
Nico Callewaert
A1
Journal Article
in
GLYCOBIOLOGY
2020
Mouse strain-dependent difference toward the staphylococcus aureus allergen serine protease-like protein D reveals a novel regulator of IL-33
Andrea Renate Teufelberger
Sharon Van Nevel
Paco Hulpiau
Maria Nordengrün
Savvas Savvides
Sarah De Graeve
Srinivas Akula
Gabriële Holtappels
Natalie De Ruyck
Wim Declercq
et al.
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2020
2019
Armc8 is a evolutionarily conserved armadillo protein involved in cell-cell adhesion complexes through multiple molecular interactions
Ismail Sahin Gül
Paco Hulpiau
Ellen Sanders
Frans Van Roy
Jolanda van Hengel
A1
Journal Article
in
BIOSCIENCE REPORTS
2019
2018
Ancient origin of the CARD-coiled coil/Bcl10/MALT1-like paracaspase signaling complex indicates unknown critical functions
Jens Staal
Yasmine Driege
Mira Haegman
Alice Borghi
Paco Hulpiau
Laurens Lievens
Ismail Sahin Gül
Srividhya Sundararaman Iyer
Amanda Gonçalves
Ineke Dhondt
et al.
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2018
Cx43 hemichannel opening in ventricular cardiomyocytes necessitates simultaneous ryanodine receptor activation and elevation of intracellular Ca2+
Alessio Lissoni
Maarten De Smet
Paco Hulpiau
Tania Martins-Marques
Nan Wang
Henrique Girao
Luc Leybaert
C3
Conference
2018
GC content of Early Metazoan genes and its impact on gene expression levels in mammalian cell lines
Ismail Sahin Gül
Jens Staal
Paco Hulpiau
Evi De Keuckelaere
Kai Kamm
Tom Deroo
Ellen Sanders
Katrien Staes
Yasmine Driege
Yvan Saeys
et al.
A1
Journal Article
in
GENOME BIOLOGY AND EVOLUTION
2018
Nanos genes and their role in development and beyond
Evi De Keuckelaere
Paco Hulpiau
Yvan Saeys
Geert Berx
Frans Van Roy
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2018
Neutralization of Junín virus by single domain antibodies targeted against the nucleoprotein
Florencia Linero
Claudia Sepúlveda
Ioanna Christopoulou
Paco Hulpiau
Luis Scolaro
Xavier Saelens
A1
Journal Article
in
SCIENTIFIC REPORTS
2018
RyR2 regulates Cx43 hemichannel [Ca2+]i-dependent activation in cardiomyocytes
Alessio Lissoni
Maarten De Smet
Tania Martins-Marques
Nan Wang
Henrique Girao
Paco Hulpiau
Luc Leybaert
C3
Conference
2018
RyR2 regulates Cx43 hemichannel [Ca2+]i-dependent activation in cardiomyocytes
Alessio Lissoni
Maarten De Smet
Tania Martins-Marques
Herique Girao
Nan Wang
Paco Hulpiau
Luc Leybaert
C3
Conference
2018
RyR2 regulates Cx43 hemichannel [Ca2+]i-dependent activation in cardiomyocytes
Alessio Lissoni
Maarten De Smet
Tania Martins-Marques
Nan Wang
Henrique Girao
Paco Hulpiau
Luc Leybaert
C3
Conference
2018
2017
ConTra v3 : a tool to identify transcription factor binding sites across species, update 2017
Lukasz Kreft
Arne Soete
Paco Hulpiau
Alexander Botzki
Yvan Saeys
Pieter De Bleser
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2017
Evolution and diversity of cadherins and catenins
Ismail Sahin Gül
Paco Hulpiau
Yvan Saeys
Frans Van Roy
A1
Journal Article
in
EXPERIMENTAL CELL RESEARCH
2017
Metazoan evolution of the armadillo repeat superfamily
Ismail Sahin Gül
Paco Hulpiau
Yvan Saeys
Frans Van Roy
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2017
The EMT transcription factor Zeb2 controls adult murine hematopoietic differentiation by regulating cytokine signaling
Jin Li
Tamara Riedt
Steven Goossens
Carmen Carrillo Garcia
Sabrina Szczepanski
Maria Brandes
Tim Pieters
Linne Dobrosch
Ines Guetgemann
Natalie Farla
et al.
A1
Journal Article
in
BLOOD
2017
2016
An evolutionary perspective on the necroptotic pathway
Yves Dondelinger
Paco Hulpiau
Yvan Saeys
Mathieu Bertrand
Peter Vandenabeele
A1
Journal Article
in
TRENDS IN CELL BIOLOGY
2016
Development and validation of a small single-domain antibody that effectively inhibits matrix metalloproteinase 8
Delphine Demeestere
Eline Dejonckheere
Sophie Steeland
Paco Hulpiau
Jurgen Haustraete
Nick Devoogdt
Rielana Wichert
Christoph Becker-Pauly
Elien Van Wonterghem
Sylviane Dewaele
et al.
A1
Journal Article
in
MOLECULAR THERAPY
2016
Efficient analysis of mouse genome sequences reveal many nonsense variants
Sophie Steeland
Steven Timmermans
Sara Van Ryckeghem
Paco Hulpiau
Yvan Saeys
Marc Van Montagu
Roosmarijn Vandenbroucke
Claude Libert
A1
Journal Article
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2016
Evolution of cadherins and associated catenins
Paco Hulpiau
Ismail Sahin Gül
Frans Van Roy
Bookchapter
in
The cadherin superfamily : key regulators of animal development and physiology
2016
Formin is associated with left-right asymmetry in the pond snail and the frog
Angus Davison
Gary S McDowell
Jennifer M Holden
Harriet F Johnson
Georgios D Koutsovoulos
M Maureen Liu
Paco Hulpiau
Frans Van Roy
Christopher M Wade
Ruby Banerjee
et al.
A1
Journal Article
in
CURRENT BIOLOGY
2016
MALT1 is not alone after all : identification of novel paracaspases
Paco Hulpiau
Yasmine Driege
Jens Staal
Rudi Beyaert
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2016
2015
Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1
Sophie Steeland
Leen Puimège
Roosmarijn Vandenbroucke
Filip Van Hauwermeiren
Jurgen Haustraete
Nick Devoogdt
Paco Hulpiau
Geert Leroux-Roels
Debby Laukens
Philip Meuleman
et al.
A1
Journal Article
in
JOURNAL OF BIOLOGICAL CHEMISTRY
2015
Passenger mutations confound interpretation of all genetically modified congenic mice
Tom Vanden Berghe
Paco Hulpiau
Liesbet Martens
Roosmarijn Vandenbroucke
Elien Van Wonterghem
Seth W Perry
Inge Bruggeman
Tatyana Divert
Sze Men Choi
Marnik Vuylsteke
et al.
A1
Journal Article
in
IMMUNITY
2015
2014
MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates
Yves Dondelinger
Wim Declercq
Sylvie Montessuit
Ria Roelandt
Amanda Gonçalves
Inge Bruggeman
Paco Hulpiau
Kathrin Weber
Clark A Sehon
Robert W Marquis
et al.
A1
Journal Article
in
CELL REPORTS
2014
2013
Cadherins
Paco Hulpiau
Frans Van Roy
Bookchapter
in
Encyclopedia of metalloproteins
2013
Mutations in the area composita protein T-catenin are associated with arrhythmogenic right ventricular cardiomyopathy
Jolanda van Hengel
Martina Calore
Barbara Bauce
Emanuela Dazzo
Elisa Mazzotti
Marzia De Bortoli
Alessandra Lorenzon
Ilena EA Li Mura
Giorgia Beffagna
Ilaria Rigato
et al.
A1
Journal Article
in
EUROPEAN HEART JOURNAL
2013
Mx proteins: antiviral gatekeepers that restrain the uninvited
Judith Verhelst
Paco Hulpiau
Xavier Saelens
A1
Journal Article
in
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
2013
New insights into the evolution of metazoan cadherins and catenins
Paco Hulpiau
Ismail Sahin Gül
Frans Van Roy
A1
Journal Article
in
Progress in Molecular Biology and Translational Science
2013
p53 promotes VEGF expression and angiogenesis in the absence of an intact p21-Rb pathway
Morvarid Farhang Ghahremani
Steven Goossens
D Nittner
X Bisteau
Sona Bartunkova
A Zwolinska
Paco Hulpiau
Katharina Haigh
Lieven Haenebalcke
Benjamin Drogat
et al.
A1
Journal Article
in
CELL DEATH AND DIFFERENTIATION
2013
2012
A bacterial glycosidase enables mannose-6-phosphate modification and improved cellular uptake of yeast-produced recombinant human lysosomal enzymes
Petra Tiels
Ekaterina Baranova
Kathleen Piens
Charlotte De Visscher
Gwenda Pynaert
Wim Nerinckx
Jan Stout
Franck Fudalej
Paco Hulpiau
Simon Tännler
et al.
A1
Journal Article
in
NATURE BIOTECHNOLOGY
2012
Evolutionary functional analysis and molecular regulation of the ZEB transcription factors
Alexander Gheldof
Paco Hulpiau
Frans Van Roy
Bram De Craene
Geert Berx
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2012
2011
ConTra v2 : a tool to identify transcription factor binding sites across species, update 2011
Stefan Broos
Paco Hulpiau
Jeroen Galle
Bart Hooghe
Frans Van Roy
Pieter De Bleser
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2011
New insights into the evolution of metazoan cadherins
Paco Hulpiau
Frans Van Roy
A1
Journal Article
in
MOLECULAR BIOLOGY AND EVOLUTION
2011
2009
Molecular evolution of the cadherin superfamily
Paco Hulpiau
Frans Van Roy
A1
Journal Article
in
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
2009
2008
ConTra: a promoter alignment analysis tool for identification of transcription factor binding sites across species
Bart Hooghe
Paco Hulpiau
Frans Van Roy
Pieter De Bleser
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2008
Text-mining assisted regulatory annotation
S AERTS
M HAEUSSLER
S VAN VOOREN
OL GRIFFITH
Paco Hulpiau
SJM JONES
SB MONTGOMERY
CM BERGMAN
A1
Journal Article
in
GENOME BIOLOGY
2008
2007
Structural investigation of cold activity and regulation of aspartate carbamoyltransferase from the extreme psychrophilic bacterium Moritella profunda
D DE VOS
X XU
Paco Hulpiau
Bjorn Vergauwen
Jozef Van Beeumen
A1
Journal Article
in
JOURNAL OF MOLECULAR BIOLOGY
2007
2005
Expression, purification, crystallization and preliminary X-ray crystallographic studies of a cold-adapted aspartate carbamoyltransferase from Moritella profunda
Dirk De Vos
Paco Hulpiau
Bjorn Vergauwen
Savvas Savvides
Jozef Van Beeumen
A1
Journal Article
in
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS
2005