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Researcher
Paco Hulpiau
Profile
Projects
Publications
Activities
40
Results
2021
Characteristic ERK1/2 signaling dynamics distinguishes necroptosis from apoptosis
François Sipieter
Benjamin Cappe
Elke De Schutter
Jolien Bridelance
Paco Hulpiau
Wim Declercq
Peter Vandenabeele
Franck Riquet
A1
Journal Article
in
ISCIENCE
2021
RyR2 regulates Cx43 hemichannel intracellular Ca2+-dependent activation in cardiomyocytes
Alessio Lissoni
Paco Hulpiau
Nan Wang
Katja Witschas
Maarten De Smet
Luc Leybaert
A1
Journal Article
in
CARDIOVASCULAR RESEARCH
2021
2020
Functional exploration of the GH29 fucosidase family
Hendrik Grootaert
Linde Van Landuyt
Paco Hulpiau
Nico Callewaert
A1
Journal Article
in
GLYCOBIOLOGY
2020
Mouse strain-dependent difference toward the staphylococcus aureus allergen serine protease-like protein D reveals a novel regulator of IL-33
Andrea Renate Teufelberger
Sharon Van Nevel
Paco Hulpiau
Savvas Savvides
Sarah De Graeve
Gabriële Holtappels
Natalie De Ruyck
Wim Declercq
Peter Vandenabeele
Dmitri Krysko
Claus Bachert
Olga Krysko
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2020
2019
Armc8 is a evolutionarily conserved armadillo protein involved in cell-cell adhesion complexes through multiple molecular interactions
Ismail Sahin Gül
Paco Hulpiau
Ellen Sanders
Frans Van Roy
Jolanda van Hengel
A1
Journal Article
in
BIOSCIENCE REPORTS
2019
2018
Ancient origin of the CARD-coiled coil/Bcl10/MALT1-like paracaspase signaling complex indicates unknown critical functions
Jens Staal
Yasmine Driege
Mira Haegman
Alice Borghi
Paco Hulpiau
Ismail Sahin Gül
Srividhya Sundararaman Iyer
Amanda Gonçalves
Ineke Dhondt
Bart Braeckman
Yvan Saeys
Frans Van Roy
Rudi Beyaert
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2018
Cx43 hemichannel opening in ventricular cardiomyocytes necessitates simultaneous ryanodine receptor activation and elevation of intracellular Ca2+
Alessio Lissoni
Maarten De Smet
Paco Hulpiau
Nan Wang
Luc Leybaert
C3
Conference
2018
GC content of Early Metazoan genes and its impact on gene expression levels in mammalian cell lines
Ismail Sahin Gül
Jens Staal
Paco Hulpiau
Evi De Keuckelaere
Tom Deroo
Ellen Sanders
Katrien Staes
Yasmine Driege
Yvan Saeys
Rudi Beyaert
Frans Van Roy
A1
Journal Article
in
GENOME BIOLOGY AND EVOLUTION
2018
Nanos genes and their role in development and beyond
Evi De Keuckelaere
Paco Hulpiau
Yvan Saeys
Geert Berx
Frans Van Roy
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2018
Neutralization of Junín virus by single domain antibodies targeted against the nucleoprotein
Florencia Linero
Ioanna Christopoulou
Paco Hulpiau
Xavier Saelens
A1
Journal Article
in
SCIENTIFIC REPORTS
2018
RyR2 regulates Cx43 hemichannel [Ca2+]i-dependent activation in cardiomyocytes
Alessio Lissoni
Maarten De Smet
Paco Hulpiau
Luc Leybaert
C3
Conference
2018
RyR2 regulates Cx43 hemichannel [Ca2+]i-dependent activation in cardiomyocytes
Alessio Lissoni
Maarten De Smet
Paco Hulpiau
Luc Leybaert
C3
Conference
2018
RyR2 regulates Cx43 hemichannel [Ca2+]i-dependent activation in cardiomyocytes
Alessio Lissoni
Maarten De Smet
Paco Hulpiau
Luc Leybaert
C3
Conference
2018
2017
ConTra v3 : a tool to identify transcription factor binding sites across species, update 2017
Arne Soete
Paco Hulpiau
Yvan Saeys
Pieter De Bleser
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2017
Evolution and diversity of cadherins and catenins
Ismail Sahin Gül
Paco Hulpiau
Yvan Saeys
Frans Van Roy
A1
Journal Article
in
EXPERIMENTAL CELL RESEARCH
2017
Metazoan evolution of the armadillo repeat superfamily
Ismail Sahin Gül
Paco Hulpiau
Yvan Saeys
Frans Van Roy
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2017
The EMT transcription factor Zeb2 controls adult murine hematopoietic differentiation by regulating cytokine signaling
Steven Goossens
Tim Pieters
Natalie Farla
Paco Hulpiau
A1
Journal Article
in
BLOOD
2017
2016
An evolutionary perspective on the necroptotic pathway
Yves Dondelinger
Paco Hulpiau
Yvan Saeys
Mathieu Bertrand
Peter Vandenabeele
A1
Journal Article
in
TRENDS IN CELL BIOLOGY
2016
Development and validation of a small single-domain antibody that effectively inhibits matrix metalloproteinase 8
Delphine Demeestere
Eline Dejonckheere
Sophie Steeland
Paco Hulpiau
Jurgen Haustraete
Elien Van Wonterghem
Sylviane Dewaele
Griet Van Imschoot
Yvan Saeys
Claude Libert
Roosmarijn Vandenbroucke
A1
Journal Article
in
MOLECULAR THERAPY
2016
Efficient analysis of mouse genome sequences reveal many nonsense variants
Sophie Steeland
Steven Timmermans
Sara Van Ryckeghem
Paco Hulpiau
Yvan Saeys
Marc Van Montagu
Roosmarijn Vandenbroucke
Claude Libert
A1
Journal Article
in
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2016
Evolution of cadherins and associated catenins
Paco Hulpiau
Ismail Sahin Gül
Frans Van Roy
Bookchapter
in
The cadherin superfamily : key regulators of animal development and physiology
2016
Formin is associated with left-right asymmetry in the pond snail and the frog
Paco Hulpiau
Frans Van Roy
A1
Journal Article
in
CURRENT BIOLOGY
2016
MALT1 is not alone after all : identification of novel paracaspases
Paco Hulpiau
Yasmine Driege
Jens Staal
Rudi Beyaert
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2016
2015
Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1
Sophie Steeland
Leen Puimège
Roosmarijn Vandenbroucke
Filip Van Hauwermeiren
Jurgen Haustraete
Paco Hulpiau
Geert Leroux-Roels
Debby Laukens
Philip Meuleman
Martine De Vos
Claude Libert
A1
Journal Article
in
JOURNAL OF BIOLOGICAL CHEMISTRY
2015
Passenger mutations confound interpretation of all genetically modified congenic mice
Tom Vanden Berghe
Paco Hulpiau
Liesbet Martens
Roosmarijn Vandenbroucke
Elien Van Wonterghem
Inge Bruggeman
Tatyana Divert
Sze Men Choi
Marnik Vuylsteke
Claude Libert
Peter Vandenabeele
A1
Journal Article
in
IMMUNITY
2015
2014
MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates
Yves Dondelinger
Wim Declercq
Ria Roelandt
Amanda Gonçalves
Inge Bruggeman
Paco Hulpiau
Kathrin Weber
Savvas Savvides
Mathieu Bertrand
Peter Vandenabeele
A1
Journal Article
in
CELL REPORTS
2014
2013
Cadherins
Paco Hulpiau
Frans Van Roy
Bookchapter
in
Encyclopedia of metalloproteins
2013
Mutations in the area composita protein T-catenin are associated with arrhythmogenic right ventricular cardiomyopathy
Jolanda van Hengel
Mara Vleeschouwers
Koen Tyberghein
Paco Hulpiau
Evelien Van Hamme
Frans Van Roy
A1
Journal Article
in
EUROPEAN HEART JOURNAL
2013
Mx proteins: antiviral gatekeepers that restrain the uninvited
Judith Verhelst
Paco Hulpiau
Xavier Saelens
A1
Journal Article
in
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
2013
New insights into the evolution of metazoan cadherins and catenins
Paco Hulpiau
Ismail Sahin Gül
Frans Van Roy
A1
Journal Article
in
Progress in Molecular Biology and Translational Science
2013
p53 promotes VEGF expression and angiogenesis in the absence of an intact p21-Rb pathway
Morvarid Farhang Ghahremani
Steven Goossens
Sona Bartunkova
Paco Hulpiau
Katharina Haigh
Lieven Haenebalcke
Benjamin Drogat
Jean-Christophe Marine
Jody Haigh
A1
Journal Article
in
CELL DEATH AND DIFFERENTIATION
2013
2012
A bacterial glycosidase enables mannose-6-phosphate modification and improved cellular uptake of yeast-produced recombinant human lysosomal enzymes
Petra Tiels
Charlotte De Visscher
Wim Nerinckx
Paco Hulpiau
Annelies Van Hecke
Nico Callewaert
A1
Journal Article
in
NATURE BIOTECHNOLOGY
2012
Evolutionary functional analysis and molecular regulation of the ZEB transcription factors
Alexander Gheldof
Paco Hulpiau
Frans Van Roy
Bram De Craene
Geert Berx
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2012
2011
ConTra v2 : a tool to identify transcription factor binding sites across species, update 2011
Stefan Broos
Paco Hulpiau
Jeroen Galle
Bart Hooghe
Frans Van Roy
Pieter De Bleser
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2011
New insights into the evolution of metazoan cadherins
Paco Hulpiau
Frans Van Roy
A1
Journal Article
in
MOLECULAR BIOLOGY AND EVOLUTION
2011
2009
Molecular evolution of the cadherin superfamily
Paco Hulpiau
Frans Van Roy
A1
Journal Article
in
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
2009
2008
ConTra: a promoter alignment analysis tool for identification of transcription factor binding sites across species
Bart Hooghe
Paco Hulpiau
Frans Van Roy
Pieter De Bleser
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2008
Text-mining assisted regulatory annotation
Paco Hulpiau
A1
Journal Article
in
GENOME BIOLOGY
2008
2007
Structural investigation of cold activity and regulation of aspartate carbamoyltransferase from the extreme psychrophilic bacterium Moritella profunda
Paco Hulpiau
Bjorn Vergauwen
Jozef Van Beeumen
A1
Journal Article
in
JOURNAL OF MOLECULAR BIOLOGY
2007
2005
Expression, purification, crystallization and preliminary X-ray crystallographic studies of a cold-adapted aspartate carbamoyltransferase from Moritella profunda
Dirk De Vos
Paco Hulpiau
Bjorn Vergauwen
Savvas Savvides
Jozef Van Beeumen
A1
Journal Article
in
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS
2005