Research Explorer

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Researcher

Ondrej Sedlacek

Awards & Distinctions

23 Results

2022

A unified kinetic Monte Carlo approach to evaluate (a)symmetric block and gradient copolymers with linear and branched chains illustrated for poly(2-oxazoline)s

Robert ConkaYoshi MarienOndrej SedlacekRichard HoogenboomPaul Van SteenbergeDagmar D'hooge

A1 Journal Article in POLYMER CHEMISTRY

Fluorinated ferrocene moieties as a platform for redox-responsive polymer F-19 MRI theranostics

Pavel SvecV Petrov, OlegJan LangPetr StepnickaOndrej GroborzDavid DunlopJan BlahutKristyna KolouchovaLenka LoukotovaOndrej Sedlacek et al.

A1 Journal Article in MACROMOLECULES

Identifying optimal synthesis protocols via the in silico characterization of (a)symmetric block and gradient copolymers with linear and branched chains

Robert ConkaYoshi MarienOndrej SedlacekPaul Van SteenbergeRichard HoogenboomDagmar D'hooge

Influence of chain length of gradient and block copoly(2-oxazoline)s on self-assembly and drug encapsulation

Ondrej SedlacekValentin BardoulaElina Vuorimaa-LaukkanenLars GeddaKatarina EdwardsAurel RadulescuGrigoriy A. MunYong GuoJunnian ZhouHongbo Zhang et al.

A1 Journal Article in SMALL

Linear poly(ethylenimine-propylenimine) random copolymers for gene delivery : from polymer synthesis to efficient transfection with high serum tolerance

M. Rachel ElzesIne MertensOndrej SedlacekBart VerbraekenAniek DoensenMaarten MeesMathias GlassnerSomdeb JanaJos M. J. PaulusseRichard Hoogenboom

A1 Journal Article in BIOMACROMOLECULES

Thermoresponsive triblock copolymers as widely applicable 19F magnetic resonance imaging tracers

Kristyna KolouchovaOndrej GroborzMiroslav SloufVit HerynekLaurens ParmentierDavid BabukaZulfiya CernochovaFilip KouckyOndrej SedlacekMartin Hruby et al.

A1 Journal Article in CHEMISTRY OF MATERIALS

Why perfectly controlled gradient copolymers don’t exist

Robert ConkaYoshi MarienOndrej SedlacekRichard HoogenboomPaul Van SteenbergeDagmar D'hooge

2021

A broad tuneable birdcage coil for mouse H-1/F-19 MR applications

M. VitM. BurianZ. BerkovaJ. LacikOndrej SedlacekRichard HoogenboomZ. RaidaD. Jirak

A1 Journal Article in JOURNAL OF MAGNETIC RESONANCE

Self-assembly, drug encapsulation, and cellular uptake of block and gradient copolymers of 2-methyl-2-oxazine and 2-n-propyl/butyl-2-oxazoline

David BabukaKristyna KolouchovaLenka LoukotovaOndrej SedlacekOndrej GroborzAneta SkarkovaAlexander ZhigunovEwa PavlovaRichard HoogenboomMartin Hruby et al.

A1 Journal Article in MACROMOLECULES

2020

Drug delivery systems based on poly(2-oxazoline)s and p(2-oxazine)s

Ondrej SedlacekRichard Hoogenboom

A1 Journal Article in ADVANCED THERAPEUTICS

Fluorinated water-soluble poly(2-oxazoline)s as highly sensitive F-19 MRI contrast agents

Ondrej SedlacekDaniel JirakMartin VitNatalia ZiolkowskaOlga JanouskovaRichard Hoogenboom

A1 Journal Article in MACROMOLECULES

Immiscibility of chemically alike amorphous polymers : phase separation of poly(2-ethyl-2-oxazoline) and poly(2‑n‑propyl-2- oxazoline)

Ella SchoolaertRonald MerckxJana BecelaereMelissa EveraertsJoachim Van GuyseOndrej SedlacekBRUNO DE GEESTGuy Van den MooterDagmar D'hoogeKaren De Clerck et al.

A1 Journal Article in MACROMOLECULES

Poly(2-ethyl-2-oxazoline) conjugates with salicylic acid via degradable modular ester linkages

Yann BernhardOndrej SedlacekJoachim Van GuyseJohan BenderZifu ZhongBruno De GeestRichard Hoogenboom

A1 Journal Article in BIOMACROMOLECULES

Poly(2-methyl-2-oxazoline) conjugates with doxorubicin : from synthesis of high drug loading water-soluble constructs to in vitro anti-cancer properties

Ondrej SedlacekAlexandra Van DriesscheAnnemiek UvynBruno De GeestRichard Hoogenboom

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

2019

Poly(2-amino-2-oxazoline)s : a new class of thermoresponsive polymers

Ondrej SedlacekDebaditya BeraRichard Hoogenboom

A1 Journal Article in POLYMER CHEMISTRY

Poly(2-oxazoline)-protein conjugates

Ondrej SedlacekVictor Retamero De La RosaRichard Hoogenboom

A1 Journal Article in EUROPEAN POLYMER JOURNAL

Solvent-control over monomer distribution in the copolymerization of 2-oxazolines and the effect of a gradient structure on self-assembly

Debaditya BeraOndrej SedlacekEtiezer JagerEwa PavlovaMaarten VergaelenRichard Hoogenboom

A1 Journal Article in POLYMER CHEMISTRY

Straightforward route to superhydrophilic poly(2-oxazoline)s via acylation of well-defined polyethylenimine

Ondrej SedlacekOlga JanouskovaBart VerbraekenRichard Hoogenboom

A1 Journal Article in BIOMACROMOLECULES

Unexpected reactivity switch in the statistical copolymerization of 2-oxazolines and 2-oxazines enabling the one-step synthesis of amphiphilic gradient copolymers

Ondrej SedlacekKathleen LavaBart VerbraekenSabah KasmiBruno De GeestRichard Hoogenboom

A1 Journal Article in JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visualization and design of the functional group distribution during statistical copolymerization

Paul Van SteenbergeOndrej SedlacekJulio César Hernández OrtizBart VerbraekenMarie-Françoise ReyniersRichard HoogenboomDagmar D'hooge

A1 Journal Article in NATURE COMMUNICATIONS

2018

Conformational properties of biocompatible poly(2-ethyl-2-oxazoline)s in phosphate buffered saline

Alexander S GubarevBryn MonneryAlexey A LezovOndrej SedlacekNikolai V TsvetkovRichard HoogenboomSergey K Filippov

A1 Journal Article in POLYMER CHEMISTRY

2017

Poly(2-ethyl-2-oxazoline) conjugate of doxorubicin bound via pH-sensitive hydrazone linker : comparison with poly[N-(2-hydroxypropyl)methacrylamide] peer

Ondrej SedlacekBryn MonneryJana MattovaOlga JanouskovaJan KuckaAnita HocherlJiri PanekRichard HoogenboomMartin Hruby

Poly(2-ethyl-2-oxazoline) conjugates with doxorubicin for cancer therapy : in vitro and in vivo evaluation and direct comparison to poly[ N -(2-hydroxypropyl)methacrylamide] analogues

Ondrej SedlacekBryn MonneryJana MattovaJan KuckaJiri PanekOlga JanouskovaAnita HocherlBart VerbraekenMaarten VergaelenMarie Zadinova et al.

A1 Journal Article in BIOMATERIALS