Research Explorer

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Researcher

Nurten Yigit

Awards & Distinctions

60 Results

2023

Dramatic impact of blood collection tube and RNA purification method on extracellular RNA transcriptomes

Jasper AnckaertFrancisco Avila CobosAnneleen DecockPhilippe DecruyenaereJill DeleuKatleen De PreterOlivier De WeverJilke De WildeBert DhondtThibaut D'huyvetter et al.

Exploration of neuroblastoma xenograft models for the analysis of tumoral cell-free RNA in murine blood plasma

Jill DeleuHanne Van DroogenbroeckJasper AnckaertJilke De WildeKaat DurinckLiselot MusJustine NuytensMuhammad RishfiKathleen SchoofsFranki Speleman et al.

Exploration of neuroblastoma xenograft models for tumor extracellular RNA profiling in murine blood plasma

Jill DeleuHanne Van DroogenbroeckJasper AnckaertAnneleen DecockJilke De WildeKaat DurinckLiselot MusJustine NuytensMuhammad RishfiKathleen Schoofs et al.

A2 Journal Article in EXRNA

Large-scale benchmarking of circRNA detection tools reveals large differences in sensitivity but not in precision

Marieke VrommanJasper AnckaertStefania BortoluzziAlessia BuratinChia-Ying ChenQinjie ChuTrees-Juen ChuangRoozbeh DehghannasiriChristoph DieterichXin Dong et al.

A1 Journal Article in NATURE METHODS

Longitudinal evaluation of serum microRNAs as biomarkers for neuroblastoma burden and therapeutic p53 reactivation

Alan Van GoethemJill DeleuNurten YigitCeline EveraertMyrthala Moreno-SmithSanjeev A VasudevanFjoralba ZekaFleur DemuynckEveline BarbieriFranki Speleman et al.

A2 Journal Article in NAR CANCER

Mammalian target of rapamycin inhibition enhances delivery and activity of antisense oligonucleotides in uveal melanoma cells

Shanna DewaeleLouis DelhayeBoel De PaepeBram BogaertRamiro MartinezJasper AnckaertNurten YigitJustine NuytensRudy Van CosterSven Eyckerman et al.

A1 Journal Article in NUCLEIC ACID THERAPEUTICS

Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study

Anneleen DecockOlivier De WeverCeline EveraertHetty HelsmoortelAn HendrixPieter MestdaghAnnelien MorlionJo VandesompeleRuben Van PaemelFrancisco Avila Cobos et al.

Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study

Anneleen DecockOlivier De WeverCeline EveraertHetty HelsmoortelAn HendrixPieter MestdaghAnnelien MorlionJo VandesompeleRuben Van PaemelFrancisco Avila Cobos et al.

2022

A 3′‐end capture sequencing method for high‐throughput targeted gene expression profiling

Eric de Bony de LavergneFien GysensNurten YigitJasper AnckaertCeline EveraertEveline Vanden EyndeKimberly VerniersWillem van SnippenbergWim TrypsteenPieter Mestdagh

A1 Journal Article in BIOTECHNOLOGY JOURNAL

Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study

Jasper AnckaertFrancisco Avila CobosAnneleen DecockPhilippe DecruyenaereJill DeleuKatleen De PreterOlivier De WeverJilke De WildeBert DhondtThibaut D'huyvetter et al.

The adrenergic-specific long non-coding RNA NESPR controls survival of neuroblastoma cells

Louis DelhayeEric de Bony de LavergneDries RombautLim Fang QiBieke DecaestekerLisa DepestelAmber LouwagieEva D'haenePieter-Jan VoldersNurten Yigit et al.

The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival

Shanna DewaeleLouis DelhayeBoel De PaepeEric de Bony de LavergneJilke De WildeKatrien VanderheydenJasper AnckaertNurten YigitJustine NuytensEveline Vanden Eynde et al.

A1 Journal Article in ONCOGENE

The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival (Sept, 10.1038/s41388-021-02006-x, 2021)

Shanna DewaeleLouis DelhayeBoel De PaepeEric James de BonyJilke De WildeKatrien VanderheydenJasper AnckaertNurten YigitJustine NuytensEveline Vanden Eynde et al.

2021

MISpheroID : a knowledgebase and transparency tool for minimum information in spheroid identity

Arne PeirsmanEva BlondeelTasdiq AhmedJasper AnckaertDominique AudenaertTom BoterbergKrisztina BuzasNeil CarragherGastone CastellaniFlávia Castro et al.

A1 Journal Article in NATURE METHODS

Substantial performance differences among RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study

Anneleen DecockOlivier De WeverCeline EveraertHetty HelsmoortelAn HendrixPieter MestdaghAnnelien MorlionJo VandesompeleRuben Van PaemelFrancisco Avila Cobos et al.

Substantial performance differences among RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study

Anneleen DecockOlivier De WeverCeline EveraertHetty HelsmoortelAn HendrixPieter MestdaghAnnelien MorlionJo VandesompeleRuben Van PaemelFrancisco Avila Cobos et al.

Validation of circular RNAs using RT‐qPCR after effective removal of linear RNAs by ribonuclease R

Marieke VrommanNurten YigitKimberly VerniersSteve LefeverJo VandesompelePieter-Jan Volders

A2 Journal Article in CURRENT PROTOCOLS

2020

Charting extracellular transcriptomes in the human biofluid RNA atlas

Eva HulstaertAnnelien MorlionFrancisco Avila CobosKimberly VerniersJustine NuytensEveline Vanden EyndeNurten YigitJasper AnckaertAnja GeertsPieter Hindryckx et al.

A1 Journal Article in CELL REPORTS

Substantial performance differences among RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control study-important considerations for liquid biopsies

Anneleen DecockJasper AnckaertCeline EveraertJustine NuytensScott KuerstenAn HendrixJo VandesompelePieter MestdaghBert DhondtRuben Van Paemel et al.

mTor inhibitor GDC-0349 improves ASO induced SAMMSON knock down resulting in enhanced anti-tumor efficacy in uveal melanoma

Shanna DewaeleBoel De PaepeLouis DelhayeEric de Bony de LavergneJilke De WildeKatrien VanderheydenJasper AnckaertNurten YigitEveline Vanden EyndeFariba Nemati et al.

mTor inhibitor GDC-0349 improves ASO induced SAMMSON knock down resulting in enhanced anti-tumor efficacy in uveal melanoma

Shanna DewaeleBoel De PaepeLouis DelhayeEric de Bony de LavergneJilke De WildeKatrien VanderheydenJasper AnckaertNurten YigitEveline Vanden EyndeFariba Nemati et al.

2019

Dramatic differences in RNA purification kit performance in the extracellular RNA quality control study : important considerations for liquid biopsies

Annelien MorlionJasper AnckaertFrancisco Avila CobosAnneleen DecockOlivier De WeverBert DhondtCeline EveraertCarolina FierroHetty HelsmoortelAn Hendrix et al.

Dramatic differences in RNA purification kit performance in the extracellular RNA quality control study : important considerations for liquid biopsies

Annelien MorlionJasper AnckaertFrancisco Avila CobosAnneleen DecockOlivier De WeverBert DhondtCeline EveraertCarolina FierroHetty HelsmoortelAn Hendrix et al.

Evaluating the impact of RNA purification kit and blood collection tube in the extracellular RNA quality control study : important considerations for liquid biopsies

Annelien MorlionJasper AnckaertFrancisco Avila CobosAnneleen DecockJill DeleuOlivier De WeverBert DhondtCeline EveraertCarolina FierroHetty Helsmoortel et al.

Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes

Dries RombautHua-Sheng ChiuBieke DecaestekerCeline EveraertNurten YigitAgathe PelthierIsabelle JanoueixChristophe BartenhagenMatthias FischerStephen Roberts et al.

A1 Journal Article in SCIENTIFIC REPORTS

SMARTer single cell total RNA sequencing

Karen VerboomCeline EveraertNathalie BolducKenneth LivakNurten YigitDries RombautJasper AnckaertMorten VenøJørgen KjemsFranki Speleman et al.

SMARTer single cell total RNA-sequencing

Karen VerboomCeline EveraertNathalie BolducKenneth LivakNurten YigitDries RombautJasper AnckaertSimon LeeMorten VenøJørgen Kjems et al.

A1 Journal Article in NUCLEIC ACIDS RESEARCH

The human biofluid RNA atlas : expanding the liquid biopsy field beyond the blood stream

Eva HulstaertKimberly VerniersJustine NuytensEveline Vanden EyndeNurten YigitJasper AnckaertAnja GeertsPeggy JacquesGuy BrusselleTHIERRY DERVEAUX et al.

2018

Longitudinal evaluation of murine serum microRNAs as biomarkers for neuroblastoma burden and therapeutic TP53 reactivation

Alan Van GoethemNurten YigitCeline EveraertMyrthala Moreno-SmithSanjeev A VasudevanFjoralba ZekaFleur DemunckEveline BarbieriFranki SpelemanPieter Mestdagh et al.

Prognostic and therapeutic implications of circulating androgen receptor gene copy number in prostate cancer patients using droplet digital polymerase chain reaction

Sarah BuelensTom ClaeysBert DhondtFilip PoelaertMatthijs VynckNurten YigitOlivier ThasPiet OstJo VandesompeleNicolaas Lumen et al.

A1 Journal Article in CLINICAL GENITOURINARY CANCER

The extracellular RNA quality control (exRNAQC) study : controlling pre-analytical variables of RNA sequencing in blood-based precision medicine

Francisco Avila CobosAnneleen DecockKatleen De PreterOlivier De WeverBram De WildeBert DhondtCeline EveraertCarolina FierroHetty HelsmoortelAn Hendrix et al.

The extracellular RNA quality control (exRNAQC) study : controlling pre-analytical variables of RNA sequencing in blood-based precision medicine

Francisco Avila CobosAnneleen DecockKatleen De PreterBert DhondtOlivier De WeverBram De WildeCeline EveraertCarolina FierroHetty HelsmoortelAn Hendrix et al.

The neuroblastoma-specific lncRNA NESPR activates PHOX2B expression and is essential for neuroblastoma cell survival

Dries RombautTiago França BrazaoLouis DelhayeEva D'haeneGiorgio MilazzoRoberto CiaccioNurten YigitCeline EveraertMatthias FischerThorsten Simon et al.

2017

Androgen receptor gene copy number detection using droplet digital PCR and its therapeutic consequences in prostate cancer patients

Sarah BuelensTom ClaeysCandy KumpsBert DhondtFilip PoelaertNurten YigitMatthijs VynckOlivier ThasPiet OstJo Vandesompele et al.

Dual targeting of MDM2 and BCL2 as a therapeutic strategy in neuroblastoma

Alan Van GoethemNurten YigitMyrthala Moreno-SmithSanjeev A VasudevanEveline BarbieriFranki SpelemanJason ShohetJo VandesompeleTom Van Maerken

A1 Journal Article in ONCOTARGET

2016

Depletion of tRNA-halves enables effective small RNA sequencing of low-input murine serum samples

Alan Van GoethemNurten YigitCeline EveraertMyrthala Moreno-SmithLiselot MusEveline BarbieriFranki SpelemanPieter MestdaghJason ShohetTom Van Maerken et al.

A1 Journal Article in SCIENTIFIC REPORTS

Identification of non-invasive biomarkers for treatment response in neuroblastoma by circulating miRNA profiling

Alan Van GoethemNurten YigitMythala Moreno-SmithCeline EveraertOlivier DelattrePieter MestdaghSaurabh AgarwalEveline BarbieriIsabelle Janoueix-LeroseyJason Shohet et al.

2011

Functional analysis of the p53 pathway in neuroblastoma cells using the small-molecule MDM2 antagonist Nutlin-3

Tom Van MaerkenAli RihaniDaniel DreidaxSarah De ClercqNurten YigitJean-Christophe MarineFrank WestermannAnne De PaepeJo VandesompeleFranki Speleman

A1 Journal Article in MOLECULAR CANCER THERAPEUTICS

2009

Aberrant methylation of candidate tumor suppressor genes in neuroblastoma

Jasmien HoebeeckEvi MichelsFilip PattynValerie CombaretJoelle VermeulenNurten YigitClaire HoyouxGenevieve LaureysAnne De PaepeFranki Speleman et al.

A1 Journal Article in CANCER LETTERS

Antitumor Activity of the Selective MDM2 Antagonist Nutlin-3 Against Chemoresistant Neuroblastoma With Wild-Type p53

Tom Van MaerkenLiesbeth FerdinandeJasmien TaildemanIrina LambertzNurten YigitLiesbeth VercruysseAli RihaniMartin MichaelisJindrich CinatlClaude Cuvelier et al.

A1 Journal Article in JOURNAL OF THE NATIONAL CANCER INSTITUTE

Chromosome 3p microsatellite allelotyping in neuroblastoma: a report on the technical hurdles

Jasmien HoebeeckBram De WildeEvi MichelsValerie CombaretNurten YigitEls De SmetNadine Van RoyEric StanbridgeNing RuGenevieve Laureys et al.

A1 Journal Article in CANCER INVESTIGATION

RNA pre-amplification enables large-scale RT-qPCR gene-expression studies on limiting sample amounts

Joëlle VermeulenStefaan DerveauxSteve LefeverEls De SmetKatleen De PreterNurten YigitAnne De PaepeFilip PattynFranki SpelemanJo Vandesompele

A2 Journal Article in BMC RESEARCH NOTES

Using real-time qPCR to evaluate RNAi-mediated gene silencing

Tom Van MaerkenPieter MestdaghS De ClercqFilip PattynNurten YigitAnne De PaepeJ C MarineFranki SpelemanJo Vandesompele

A2 Journal Article in BioTechniques Protocol Guide

2008

EVI1 overexpression in t(3;17) positive myeloid malignancies results from juxtaposition of EVI1 to the MSI2 locus at 17q22

An De WeerFranki SpelemanBarbara CauwelierNadine Van RoyNurten YigitBruno VerhasseltBarbara De MoerlooseYves BenoitLucien NoensDominik Selleslag et al.

A1 Journal Article in HAEMATOLOGICA-THE HEMATOLOGY JOURNAL

Real-time qPCR as a tool for evaluating RNAi-mediated gene silencing

Tom Van MaerkenPieter MestdaghSarah De ClercqFilip PattynNurten YigitAnne De PaepeJean-Christophe MarineFranki SpelemanJo Vandesompele

A2 Journal Article in Bioradiations

Unmasking of epigenetically silenced microRNAs in neuroblastoma

Jasmien HoebeeckGeert DeclerckPieter MestdaghFilip PattynKatleen De PreterJoëlle VermeulenNurten YigitAnne De PaepeFranki SpelemanJo Vandesompele

2007

De bijdrage van M-FISH aan de moleculaire diagnostiek in de hemato-oncologie

Bruce PoppeNadine Van RoyNurten YigitAnne De PaepeFranki Speleman

A2 Journal Article in Ned Tijdschr Hematol

Genome wide promoter methylation analysis in neuroblastoma with perspectives for integrated molecular profiling

Jasmien HoebeeckMaté OngenaertEvi MichelsKatleen De PreterJoëlle VermeulenNurten YigitAnne De PaepeWim Van CriekingeFranki SpelemanJo Vandesompele

High resolution tiling-path BAC array deletion mapping suggests commonly involved 3p21-p22 tumor suppressor genes in neuroblastoma and more frequent tumors

Jasmien HoebeeckEvi MichelsBjörn MentenNadine Van RoyAngelika EggertAlexander SchrammKatleen De PreterNurten YigitEls De SmetAnne De Paepe et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

2006

EVII is consistently expressed as principal transcript in common and rare recurrent 3q26 rearrangements

Bruce PoppeN DASTUGUEJo VandesompeleBarbara CauwelierB DE SMETNurten YigitAnne De PaepeJ CERVERAC RECHERV DE MAS et al.

A1 Journal Article in GENES CHROMOSOMES & CANCER

Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes

Katleen De PreterJo VandesompelePierre HeimannNurten YigitSiv BeckmanAlexander SchrammAngelika EggertRaymond L StallingsYves BenoitMarleen Renard et al.

A1 Journal Article in GENOME BIOLOGY

Small-molecule MDM2 antagonists as a new therapy concept for neuroblastoma

Tom Van MaerkenFranki SpelemanJ VERMEULENIrina LambertzSarah De ClercqEls De SmetNurten YigitV COPPENSJan PhilippéAnne De Paepe et al.

A1 Journal Article in CANCER RESEARCH

The von Hippel-Lindau tumor suppressor gene expression level has prognostic value in neuroblastoma

Jasmien HoebeeckJo VandesompeleHelén NissonKatleen De PreterNadine Van RoyEls De SmetNurten YigitAnne De PaepeGenevieve LaureysSven Påhlman et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

2005

HOYA gene cluster rearrangement in a t(7;9)(p15;q34) in a child with MDS

Bruce PoppeNurten YigitBarbara De MoerlooseAnne De PaepeYves BenoitFranki Speleman

A1 Journal Article in CANCER GENETICS AND CYTOGENETICS

Novel cryptic chromosomal rearrangements in childhood acute lymphoblastic leukemia detected by multiple color fluorescent in situ hybridization

Bruce PoppeBarbara CauwelierH VAN LIMBERGENNurten YigitJan PhilippéBruno VerhasseltAnne De PaepeYves BenoitFranki Speleman

A1 Journal Article in HAEMATOLOGICA-THE HEMATOLOGY JOURNAL

PAX5/IGH rearrangement is a recurrent finding in a subset of aggressive B-NHL with complex chromosomal rearrangements

Bruce PoppeP DE PAEPEL MICHAUXN DASTUGUEC BASTARDC HERENSELS MOREAUF CAVAZZININurten YigitH VAN LIMBERGEN et al.

A1 Journal Article in GENES CHROMOSOMES & CANCER

Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11

Katleen De PreterJo VandesompeleBjörn MentenPhilippa CarrHeike FieglerAnders EdsjöNigel P CarterNurten YigitWim WaelputNadine Van Roy et al.

A1 Journal Article in BMC GENOMICS

Rapid detection of VHL exon deletions using real-time quantitative PCR

Jasmien HoebeeckR VAN DER LUIJTBruce PoppeEls De SmetNurten YigitKathleen ClaesR ZEWALDGJ DE JONGAnne De PaepeFranki Speleman et al.

A1 Journal Article in LABORATORY INVESTIGATION

2004

Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies

Bruce PoppeJo VandesompeleC SCHOCHC LINDVALLK MROZEKCD BLOOMFIELDHB BEVERLOOL MICHAUXN DASTUGUEC HERENS et al.

A1 Journal Article in BLOOD

2001

Molecular characterization of a t(2;3)(p23;q26): A recurrent translocation involving the EVI1 gene

Bruce PoppeNurten YigitP MARYNENA HAGEMEIJERH VAN LIMBERGENB DE SMETAnne De PaepeFranki Speleman