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Researcher
Nincy Debeuf
Profile
Projects
Publications
Activities
Awards & Distinctions
18
Results
2025
Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that clamp the spike at its base
Sieglinde De Cae
Inge Van Molle
Loes van Schie
Sophie R. Shoemaker
Julie Deckers
Nincy Debeuf
Sahine Lameire
Wim Nerinckx
Kenny Roose
Daria Fijalkowska
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2025
2024
Inhaled GM-CSF administered during ongoing pneumovirus infection alters myeloid and CD8 T cell immunity without affecting disease outcome
Nincy Debeuf
Julie Deckers
Sahine Lameire
Cedric Bosteels
Hamida Hammad
Bart Lambrecht
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2024
TCR transgenic clone selection guided by immune receptor analysis and single-cell RNA expression of polyclonal responders
Nincy Debeuf
Sahine Lameire
Manon Vanheerswynghels
Julie Deckers
Caroline De Wolf
Wendy Toussaint
Rein Verbeke
Kevin Verstaen
Hamida Hammad
Stijn Vanhee
et al.
A2
Journal Article
in
ELIFE
2024
2023
A Complement Atlas identifies interleukin 6 dependent alternative pathway dysregulation as a key druggable feature of COVID-19
Karel Van Damme
Levi Hoste
Jozefien Declercq
Elisabeth De Leeuw
Bastiaan Maes
Liesbet Martens
Roos Colman
Robin Browaeys
Cedric Bosteels
Stijn Verwaerde
et al.
Preprint
2023
A complement atlas identifies interleukin-6-dependent alternative pathway dysregulation as a key druggable feature of COVID-19
Karel Van Damme
Levi Hoste
Jozefien Declercq
Elisabeth De Leeuw
Bastiaan Maes
Liesbet Martens
Roos Colman
Robin Browaeys
Cedric Bosteels
Stijn Verwaerde
et al.
A1
Journal Article
in
SCIENCE TRANSLATIONAL MEDICINE
2023
2022
Efficacy and safety of the investigational complement C5 inhibitor zilucoplan in patients hospitalized with COVID-19 : an open-label randomized controlled trial
Elisabeth De Leeuw
Karel Van Damme
Jozefien Declercq
Cedric Bosteels
Bastiaan Maes
Simon Tavernier
Laurent Detalle
Trevor Smart
Sophie Glatt
Nincy Debeuf
et al.
A1
Journal Article
in
RESPIRATORY RESEARCH
2022
Emerging paradigms in type 2 immunity
Hamida Hammad
Nincy Debeuf
Helena Catharine Aegerter
Andrew Brown
Bart Lambrecht
A1
Journal Article
in
ANNUAL REVIEW OF IMMUNOLOGY
2022
Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment
Cedric Bosteels
Karel Van Damme
Elisabeth De Leeuw
Jozefien Declercq
Bastiaan Maes
Victor Bosteels
Levi Hoste
Leslie Naesens
Nincy Debeuf
Julie Deckers
et al.
A1
Journal Article
in
CELL REPORTS MEDICINE
2022
The STE20 kinase TAOK3 controls the development of house dust mite-induced asthma in mice
Bastiaan Maes
Ursula Smole
Matthias Vanderkerken
Kim Deswarte
Justine Van Moorleghem
Karl Vergote
Manon Vanheerswynghels
Caroline De Wolf
Sofie De Prijck
Nincy Debeuf
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2022
2021
IRE1 beta does not affect mucus secretion during allergic asthma development in a house dust mite murine model
Eva Cloots
Nincy Debeuf
Kim Deswarte
Farzaneh Fayazpour
Manon Vanheerswynghels
Caroline De Wolf
Evelien Van de Velde
Hamida Hammad
Bart Lambrecht
Sven Eyckerman
et al.
A1
Journal Article
in
ALLERGY
2021
2020
Inflammatory type 2 cDCs acquire features of cDC1s and macrophages to orchestrate immunity to respiratory virus infection
Cedric Bosteels
Katrijn Neyt
Manon Vanheerswynghels
Mary van Helden
Dorine Sichien
Nincy Debeuf
Sofie De Prijck
Victor Bosteels
Niels Vandamme
Liesbet Martens
et al.
A1
Journal Article
in
IMMUNITY
2020
2019
ORMDL3 in the regulation of sphingolipid synthesis and in the pathogenesis of allergic asthma
Nincy Debeuf
Bart Lambrecht
Sophie Janssens
Dissertation
2019
The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice
Nincy Debeuf
Assem Zhakupova
Regula Steiner
Sofie Van Gassen
Kim Deswarte
Farzaneh Fayazpour
Justine Van Moorleghem
Karl Vergote
Benjamin Pavie
Kelly Lemeire
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2019
2018
Eicosanoid control over antigen presenting cells in asthma
Nincy Debeuf
Bart Lambrecht
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2018
2017
Murine models of allergic asthma
Eline Haspeslagh
Nincy Debeuf
Hamida Hammad
Bart Lambrecht
Bookchapter
in
Inflammation : methods and protocols
2017
2016
Mouse models of asthma
Nincy Debeuf
Eline Haspeslagh
Mary van Helden
Hamida Hammad
Bart Lambrecht
Bookchapter
in
Current protocols in mouse biology
2016
ORMDL3 expression levels have no influence on the activity of serine palmitoyltransferase
Assem Zhakupova
Nincy Debeuf
Michiel Krols
Wendy Toussaint
Leen Vanhoutte
Irina Alecu
Zoltán Kutalik
Peter Vollenweider
Daniela Ernst
Arnold von Eckardstein
et al.
A1
Journal Article
in
FASEB JOURNAL
2016
2015
Fascin actin bundling controls podosome turnover and disassembly while cortactin is involved in podosome assembly by its SH3 domain in THP-1 macrophages and dendritic cells
Isabel Van Audenhove
Nincy Debeuf
Ciska Boucherie
Jan Gettemans
A1
Journal Article
in
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
2015