Research Explorer

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Researcher

Niels Vander Elst

Awards & Distinctions

22 Results

2024

Endolysin NC5 improves early cloxacillin treatment in a mouse model of Streptococcus uberis mastitis

Niels Vander ElstJulie BellemansRob LavigneYves BriersEvelyne Meyer

A1 Journal Article in APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

2023

Development of engineered endolysins with in vitro intracellular activity against streptococcal bovine mastitis‐causing pathogens

Niels Vander ElstJoni BertHerman FavoreelRob LavigneEvelyne MeyerYves Briers

A1 Journal Article in MICROBIAL BIOTECHNOLOGY

Endolysin NC5 improves early cloxacillin treatment in a mouse model for bovine Streptococcus uberis mastitis

Julie BellemansNiels Vander ElstRob LavigneYves BriersEvelyne Meyer

Engineering of bacteriophage-derived endolysins to treat streptococcal mammary gland infections

Niels Vander ElstEvelyne MeyerYves BriersRob Lavigne

Priming of the murine mammary gland with Staphylococcus chromogenes IM reduces bacterial growth of Streptococcus uberis : a proof-of-concept study

Niels Vander ElstJulie BellemansJonas SteenbruggeChloë GeeromsKoen BreyneSofie PiepersBruno Toledo-SilvaFernando Nogueira De SouzaFreddy HaesebrouckSarne De Vliegher et al.

A1 Journal Article in VETERINARY RESEARCH

2022

A method for the purification of non-pyrogenic bacteriophage derived endolysins with an in vitro or in vivo application

Niels Vander ElstVincent De MaesschalckPhilippe De GrooteEvelyne MeyerRob LavigneYves Briers

Characterization of endolysins PlySs2 & -9 with in vitro lytic activity against bovine mastitis Streptococcus uberis

Niels Vander ElstSara B. LindenEvelyne MeyerRob LavigneYves BriersDaniel C. Nelson

One cisplatin dose provides durable stimulation of anti-tumor immunity and alleviates anti-PD-1 resistance in an intraductal model for triple-negative breast cancer

Jonas SteenbruggeJulie BellemansNiels Vander ElstKristel DemeyereJosephine De VliegherTimothy PereraOlivier De WeverWim Van Den BroeckWard De SpiegelaereNiek Sanders et al.

A1 Journal Article in ONCOIMMUNOLOGY

One cisplatin dose suffices to maintain anti-tumor immunity and enhances anti-PD-1 efficacy in an intraductal model for triple-negative breast cancer

Jonas SteenbruggeJulie BellemansNiels Vander ElstKristel DemeyereNiek SandersEvelyne Meyer

2021

Immunomodulation by cisplatin chemotherapy in an immunocompetent intraductal model for triple-negative breast cancer

Jonas SteenbruggeNiels Vander ElstKristel DemeyereJosephine De VliegherAnnegret Van der AaEric CiamporceroTimothy PereraEvelyne Meyer

OMO-1 reduces progression and enhances cisplatin efficacy in a 4T1-based non-c-MET addicted intraductal mouse model for triple-negative breast cancer

Jonas SteenbruggeNiels Vander ElstKristel DemeyereOlivier De WeverNiek SandersWim Van Den BroeckEric CiamporceroTimothy PereraEvelyne Meyer

A1 Journal Article in NPJ BREAST CANCER

Splenic immunomodulatory effects of cisplatin in an immunocompetent intraductal model for triple-negative breast cancer

Jonas SteenbruggeNiels Vander ElstKristel DemeyereJosephine De VliegherAnnegret Van der AaEric CiamporceroTimothy PereraEvelyne Meyer

Unexpected effects of a selective and potent c-MET inhibitor in an immunocompetent intraductal model for triple-negative breast cancer

Jonas SteenbruggeNiels Vander ElstKristel DemeyereOlivier De WeverNiek SandersWim Van Den BroeckAnnegret Van der AaEric CiamporceroTimothy PereraEvelyne Meyer

2020

Characterization of the bacteriophage-derived endolysins PlySs2 and PlySs9 with in vitro lytic activity against bovine mastitis streptococcus uberis

Niels Vander ElstSara B. LindenRob LavigneEvelyne MeyerYves BriersDaniel C. Nelson

A1 Journal Article in ANTIBIOTICS-BASEL

Enterobactin deficiency in a coliform mastitis isolate decreases its fitness in a murine model : a preliminary host-pathogen interaction study

Niels Vander ElstKoen BreyneJonas SteenbruggeAmanda Jane GibsonDavid George Emslie SmithPierre GermonDirk WerlingEvelyne Meyer

A1 Journal Article in FRONTIERS IN VETERINARY SCIENCE

2019

Comparative immune profiling of an aggressive 4T1-based versus a non-aggressive Py230-based intraductal model for triple-negative breast cancer

Jonas SteenbruggeNiels Vander ElstKristel DemeyereOlivier De WeverSteven Van LaereEvelyne Meyer

Comparative profiling of metastatic 4T1- vs. non-metastatic Py230-based mammary tumors in an intraductal model for triple-negative breast cancer

Jonas SteenbruggeNiels Vander ElstKristel DemeyereOlivier De WeverNiek SandersWim Van Den BroeckLuc DirixSteven Van LaereEvelyne Meyer

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Development of the PlyC endolysin as a bovine mastitis therapeutic for lactating dairy cows

Sara B LindenCynthia M ScholteNiels Vander ElstKasey M MoyesDaniel C Nelson

The PlySs9 endolysin and its amidase subdomain reveal potential roles in the treatment of Gram-positive bovine mastitis

Niels Vander ElstSara B LindenRob LavigneEvelyne MeyerDaniel C Nelson

The PlySs9 endolysin contains unique catalytic domains and is a potential therapeutic against Streptococcus suis

Sara B LindenNiels Vander ElstDaniel C Nelson

2018

Potential therapeutic application of bacteriophages and phage-derived endolysins as alternative treatment of bovine mastitis

Niels Vander ElstEvelyne Meyer

A1 Journal Article in VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT

Tumor immune profiling and host NF-kappaB activity assessment in a novel Py230-based intraductal model for triple-negative breast cancer

Jonas SteenbruggeNiels Vander ElstKristel DemeyereNiek SandersOlivier De WeverSteven Van LaereEvelyne Meyer