Research Explorer

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Researcher

Niels Vandamme

Publications & Research Data

Awards & Distinctions

82 Results

2026

Cross-species cellular mapping and humanization of Fcγ receptors to advance antibody modeling

Karel Van DammeDorine SichienKatrien Van Der BorghtJustine Van MoorleghemSofie Van GassenJoseph JorssenSeppe De WinterElisabeth De LeeuwCaihong WangQingqing Chai et al.

A1 Journal Article in SCIENCE IMMUNOLOGY

STAT1 drives the immune landscape of murine Toll-like receptor 9-induced liver inflammation

Amber De VisscherJarne BelienEline BernaertsMarte VandeputBert Malengier-DevliesFran PrenenHanne MeersLiliana SokolTania MiteraNele Berghmans et al.

A1 Journal Article in JHEP REPORTS

2025

Cystic fibrosis as a modulable model for CFTR-related Immune dysregulation

Leander JonckheereCedric BosteelsIris JanssensSebastian RiemannLieve Vande SandeTania MaesYannick Vande WeygaerdeStephanie Van BiervlietFilomeen HaerynckBart Lambrecht et al.

Cystic fibrosis as a modulable model for CFTR-related immune dysregulation

Leander JonckheereCedric BosteelsIris JanssensSebastian RiemannLieve Vande SandeTania MaesYannick Vande WeygaerdeStephanie Van BiervlietFilomeen HaerynckBart Lambrecht et al.

Lipid nanoparticles as a tool to dissect dendritic cell maturation pathways

Sofie RennenVictor BosteelsClint De NolfSandra MaréchalJessica VettersKaro Van LilGreta WebbJanne SwinnenEvelien Van De VeldeFarzaneh Fayazpour et al.

A1 Journal Article in CELL REPORTS

Lipid nanoparticles as a tool to dissect dendritic cell maturation pathways

Sofie RennenVictor BosteelsClint De NolfGreta WebbKaro Van LilSandra MaréchalJessica VettersEvelien Van De VeldeFarzaneh FayazpourRia Roelandt et al.

The development of a custom spatial transcriptomics platform to study cellular heterogeneity induced by targeted therapies in neuroblastoma

Hanne Van DroogenbroeckFranco Alexander Poma SotoBrecht SoulliaertMark SomozaMaya GridharCharlotte ScottRobrecht RaedtNiels VandammeBram De WildeTom Van Maerken et al.

Unmasking budgerigar splenic leukocyte populations with single‐cell transcriptomics and multiplex RNA in situ hybridization

Anne De MeystKelly LemeireAmanda GonçalvesNiels VandammeDaisy Vanrompay

A1 Journal Article in JOURNAL OF IMMUNOLOGY RESEARCH

2024

Cystic fibrosis and the role of CFTR in circulating immune cells : a human single-cell atlas

Leander JonckheereCedric BosteelsIris JanssensYannick Vande WeygaerdeTania MaesRobin BrowaeysNiels VandammeSimon TavernierBart LambrechtEva Van Braeckel

Infection history imprints prolonged changes to the epigenome, transcriptome and function of Kupffer cells

Mohamed Amer MusratiBenoit StijlemansAbdulkader AzouzDaliya KanchevaSarah MesbahiEva HadadiEls LebeggeLeen AliKaren De VlaminckIsabelle Scheyltjens et al.

A1 Journal Article in JOURNAL OF HEPATOLOGY

Intestinal stroma guides monocyte differentiation to macrophages through GM-CSF

Egle KvedaraiteMagda LourdaNatalia MouratidouTim DukingAvinash PadhiKirsten MollPaulo CzarnewskiIndranil SinhaIoanna XagorarisEfthymia Kokkinou et al.

A1 Journal Article in NATURE COMMUNICATIONS

Knocking out CD70 rescues CD70-specific nanoCAR T cells from antigen-induced exhaustion

Stijn De MunterJuliane L. BuhlLaurenz De CockAlexander Van ParysWillem DaneelsEva PascalLucas DeseinsJoline IngelsGlenn GoetgelukHanne Jansen et al.

A1 Journal Article in CANCER IMMUNOLOGY RESEARCH

Lack of functional TCR-epitope interaction is associated with herpes zoster through reduced downstream T cell activation

Marlies BoerenNicky de VrijMy K. HaSebastiaan ValkiersAisha SouquetteSofie GielisMaria KuznetsovaJolien SchippersEsther BartholomeusJohan Van den Bergh et al.

A1 Journal Article in CELL REPORTS

Neoantigen-targeted dendritic cell vaccination in lung cancer patients induces long-lived T cells exhibiting the full differentiation spectrum

Joline IngelsLaurenz De CockDieter StevensRupert MayerFabien Henri TheryGuillem Sanchez SanchezDavid VermijlenKarin WeeningSaskia De SmetNele Lootens et al.

A1 Journal Article in CELL REPORTS MEDICINE

S100A8-enriched microglia populate the brain of tau-seeded and accelerated aging mice

Roxane GruelBaukje BijnensJohanna Van Den DaeleSofie ThysRoland WillemsDirk WuytsDebby Van DamPeter VerstraelenRosanne VerbovenJana Roels et al.

A1 Journal Article in AGING CELL

The role of interleukin-8 in primary sclerosing cholangitis-associated immune cell dysregulation

Lander HeyerickKevin De MuynckZenzi De VosSander LefereJana RoelsNiels VandammeAnja GeertsSarah RaevensXavier VerhelstHans Van Vlierberghe et al.

ThymoSpheres culture : a model to study human polyclonal unconventional T cells

Lore BillietHanne JansenMelissa PilleLena BoehmeGuillem Sanchez SanchezLaurenz De CockGlenn GoetgelukEva PascalStijn De MunterLucas Deseins et al.

A1 Journal Article in EUROPEAN JOURNAL OF IMMUNOLOGY

ZEB2 drives intra-tumor heterogeneity and skin squamous cell carcinoma formation with distinct EMP transition states

Jeroen VerstappeNicolas SkrypekJordy De ConinckBieke SoenJoachim TaminauMarianthi TatariKenneth BruneelNele LoretKato De ClercqCaroline Van den Broecke et al.

A1 Journal Article in ISCIENCE

2023

A bispecific Clec9A-PD-L1 targeted type I interferon profoundly reshapes the tumor microenvironment towards an antitumor state

Sandra Van LintAlexander Van ParysBram Van Den EeckhoutNiels VandammeStephane PlaisanceAnnick VerheeDominiek CatteeuwElke RoggeJennifer De GeestNele Vanderroost et al.

A1 Journal Article in MOLECULAR CANCER

A plasma miR-193b-365 signature combined with age and glycemic status predicts response to Lactococcus lactis-based antigen-specific immunotherapy in new-onset type 1 diabetes

Gabriele SassiGiada LicataGiuliana VentrigliaAmber WoutersPierre LemaitreRuth SeurinckAlessia MoriGiuseppina Emanuela GriecoSamal BissenovaDarcy Ellis et al.

A1 Journal Article in DIABETES

Autophagy critically controls skin inflammation and apoptosis-induced stem cell activation

Lisette Van HoveAnnagiada TonioloMohammad GhiaslooKim LecomteFleur BooneMaarten CiersKris RaaijmakersNiels VandammeJana RoelsSophia Maschalidi et al.

A1 Journal Article in AUTOPHAGY

Blocking abundant RNA transcripts by high-affinity oligonucleotides during transcriptome library preparation

Celine EveraertJasper VerwiltKimberly VerniersNiels VandammeAlvaro Marcos RubioJo VandesompelePieter Mestdagh

A1 Journal Article in BIOLOGICAL PROCEDURES ONLINE

Cell type-specific attenuation of brassinosteroid signaling precedes stomatal asymmetric cell division

Kim EunjiCheng ZhangBoyu GuoThomas EekhoutAnaxi HoubaertJos WendrichNiels VandammeManish TiwariClaire Simon--VezoIsabelle Vanhoutte et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Knocking out CD70 rescues CD70-specific nanoCAR T cells from antigen induced exhaustion

Stijn De MunterJuliane BuhlLaurenz De CockAlexander Van ParysWillem DaneelsEva PascalLucas DeseinsJoline IngelsGlenn GoetgelukLore Billiet et al.

LXR signaling controls homeostatic dendritic cell maturation

Victor BosteelsSandra MaréchalClint De NolfSofie RennenJonathan MaelfaitSimon TavernierJessica VettersEvelien Van De VeldeFarzaneh FayazpourKim Deswarte et al.

A1 Journal Article in SCIENCE IMMUNOLOGY

Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage

Lore BillietLaurenz De CockGuillem Sanchez SanchezRupert MayerGlenn GoetgelukStijn De MunterMelissa PilleJoline IngelsHanne JansenKarin Weening et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

The single-cell transcriptional landscape of innate and adaptive lymphocytes in pediatric-onset colitis

Efthymia KokkinouTea SoiniRam Vinay PandeyAline van AckerJakob TheorellPaulo CzarnewskiEgle KvedaraiteNiels VandammeMagda LourdaChiara Sorini et al.

A1 Journal Article in CELL REPORTS MEDICINE

2022

Blocking unwanted sequences by target specific high-affinity binding oligonucleotides during transcriptome library preparation

Celine EveraertJasper VerwiltKimberly VerniersNiels VandammeAlvaro Marcos RubioJo VandesompelePieter Mestdagh

Cell type-specific attenuation of brassinosteroid signalling drives stomatal asymmetric cell division

Kim EunjiCheng ZhangBoyu GuoThomas EekhoutAnaxi HoubaertJos WendrichNiels VandammeManish TiwariClaire Simon--VezoIsabelle Vanhoutte et al.

Comparative analysis of antibody- and lipid-based multiplexing methods for single-cell RNA-seq

Viacheslav MylkaIrina MatetoviciSuresh PoovathingalJeroen AertsNiels VandammeRuth SeurinckKevin VerstaenGert HulselmansSilvie van den HoeckeIsabelle Scheyltjens et al.

A1 Journal Article in GENOME BIOLOGY

Distinct transcriptional programs in ascitic and solid cancer cells induce different responses to chemotherapy in high-grade serous ovarian cancer

Nele LoretNiels VandammeJordy De ConinckJoachim TaminauKato De ClercqGillian BlanckeSven JonckheereSteven GoossensKelly LemeireSofie De Prijck et al.

A1 Journal Article in MOLECULAR CANCER RESEARCH

Efficacy of CD40 agonists is mediated by distinct cDC subsets and subverted by suppressive macrophages

Aleksandar MurgaskiMate KissHelena Van DammeDaliya KanchevaIsaure VanmeerbeekJiri KeirsseEva HadadiJan BrughmansSana M. ArnoukAhmed E. I. Hamouda et al.

A1 Journal Article in CANCER RESEARCH

Glutathione-dependent redox balance characterizes the distinct metabolic properties of follicular and marginal zone B cells

Davide G. FranchinaHenry KurniawanMelanie GrusdatCarole BinsfeldLuana GuerraLynn BonettiLeticia Soriano-BaguetAnouk EwenTakumi KobayashiSophie Farinelle et al.

A1 Journal Article in NATURE COMMUNICATIONS

How tech-savvy employees make the difference in core facilities : recognizing core facility expertise with dedicated career tracks

Saskia LippensDominique AudenaertAlexander BotzkiStefaan DerveauxBart GhesquièreGeert GoeminneReza HassanzadehJurgen HaustraeteFrancis ImpensJochen Lamote et al.

Editorial material

Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment

Cedric BosteelsKarel Van DammeElisabeth De LeeuwJozefien DeclercqBastiaan MaesVictor BosteelsLevi HosteLeslie NaesensNincy DebeufJulie Deckers et al.

A1 Journal Article in CELL REPORTS MEDICINE

MLKL deficiency in BrafV600EPten-/- melanoma model results in a modest delay of nevi development and reduced lymph node dissemination in male mice

Sofie MartensNozomi TakahashiGillian BlanckeNiels VandammeHanne VerschuereTatyana DivertMarnik VuylstekeGeert BerxPeter Vandenabeele

A1 Journal Article in CELL DEATH & DISEASE

Single-cell RNA and protein profiling of immune cells from the mouse brain and its border tissues

Isabelle ScheyltjensHannah Van HoveKaren De VlaminckDaliya KanchevaJonathan BastosMonica Vara-PerezAna Rita Pombo AntunesLiesbet MartensCharlotte ScottJo Van Ginderachter et al.

A1 Journal Article in NATURE PROTOCOLS

Single-cell transcriptomics sheds light on the identity and metabolism of developing leaf cells

Rubén Tenorio BerrioKevin VerstaenNiels VandammeJulie PevernagieIgnacio AchónJulie Van DuyseGert Van IsterdaelYvan SaeysLieven De VeylderDirk Inzé et al.

A1 Journal Article in PLANT PHYSIOLOGY

TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C

Levi HosteLisa RoelsLeslie NaesensVictor BosteelsStijn VanheeSam DupontCedric BosteelsRobin BrowaeysNiels VandammeKevin Verstaen et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

2021

Advances and opportunities in single-cell transcriptomics for plant research

Carolin SeyfferthJim RenemaJos WendrichThomas EekhoutRuth SeurinckNiels VandammeBernhard BlobYvan SaeysYrjo HelariuttaKenneth D. Birnbaum et al.

A1 Journal Article in ANNUAL REVIEW OF PLANT BIOLOGY

Fibrotic enzymes modulate wound-induced skin tumorigenesis

Lisette Van HoveKim LecomteJana RoelsNiels VandammeHanna-Kaisa VikkulaIsabelle HoorensKatia OngenaeTino HochepiedGiacomo DonatiYvan Saeys et al.

A1 Journal Article in EMBO REPORTS

OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity

Esther HosteKim LecomteKarl AnnusverNiels VandammeJana RoelsSophia MaschalidiLien VerboomHanna-Kaisa VikkulaMozes SzeLisette Van Hove et al.

A1 Journal Article in NATURE COMMUNICATIONS

Pancreas morphogenesis and homeostasis depends on tightly regulated Zeb1 levels in epithelial cells

Maria Lasierra LosadaMelissa PaulerNiels VandammeSteven GoossensGeert BerxMoritz LeppkesHarald SchuhwerkSimone BrabletzThomas BrabletzMarc P. Stemmler

A1 Journal Article in CELL DEATH DISCOVERY

Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization

Ana Rita Pombo AntunesIsabelle ScheyltjensFrancesca LodiJulie MessiaenAsier AntoranzJohnny DuerinckDaliya KanchevaLiesbet MartensKaren De VlaminckHannah Van Hove et al.

A1 Journal Article in NATURE NEUROSCIENCE

The spleen as a sanctuary site for residual leukemic cells following ABT-199 monotherapy in ETP-ALL

Alessandra Di GrandeSofie PeirsPaul D. DonovanMaaike Van TrimpontJulie MorscioBéatrice LintermansLindy ReunesNiels VandammeSteven GoossensHien Anh Nguyen et al.

A1 Journal Article in BLOOD ADVANCES

Therapeutic depletion of CCR8(+) tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy

Helena Van DammeBruno DombrechtMate KissHeleen RooseElizabeth AllenEva Van OvermeireDaliya KanchevaLiesbet MartensAleksandar MurgaskiPauline Madeleine Rachel Bardet et al.

A1 Journal Article in JOURNAL FOR IMMUNOTHERAPY OF CANCER

2020

A cell atlas of human thymic development defines T cell repertoire formation

Jong-Eun ParkRachel A. BottingCecilia Domínguez CondeDorin-Mirel PopescuMarieke LavaertDaniel J. KunzIssac GohEmily StephensonRoberta RagazziniElizabeth Tuck et al.

A1 Journal Article in SCIENCE

Inflammatory type 2 cDCs acquire features of cDC1s and macrophages to orchestrate immunity to respiratory virus infection

Cedric BosteelsKatrijn NeytManon VanheerswynghelsMary van HeldenDorine SichienNincy DebeufSofie De PrijckVictor BosteelsNiels VandammeLiesbet Martens et al.

A1 Journal Article in IMMUNITY

Integrated scRNA-seq identifies human postnatal thymus seeding progenitors and regulatory dynamics of differentiating immature thymocytes

Marieke LavaertKai Ling LiangNiels VandammeJong-Eun ParkJuliette RoelsMonica S. KowalczykBo LiOrr AshenbergMarcin TabakaDanielle Dionne et al.

A1 Journal Article in IMMUNITY

Intrinsic balance between ZEB family members is important for melanocyte homeostasis and melanoma progression

Kenneth BruneelJeroen VerstappeNiels VandammeGeert Berx

A1 Journal Article in CANCERS

Osteopontin expression identifies a subset of recruited macrophages distinct from Kupffer cells in the fatty liver

Anneleen RemmerieLiesbet MartensTinne THONEAngela CastoldiRuth SeurinckBenjamin PavieJoris RoelsBavo VannesteSofie De PrijckMathias Vanhockerhout et al.

A1 Journal Article in IMMUNITY

Publisher correction : Zeb2 drives invasive and microbiota-dependent colon carcinoma

Karolina SlowickaIoanna PettaGillian BlanckeEsther HosteEmilie DumasMozes SzeHanna-Kaisa VikkulaEnrico RadaelliJody J. HaighSven Jonckheere et al.

The EMT transcription factor ZEB2 promotes proliferation of primary and metastatic melanoma while suppressing an invasive, mesenchymal-like phenotype

Niels VandammeGeertrui DeneckerKenneth BruneelGillian BlanckeOzden AkayJoachim TaminauJordy De ConinckEva De SmedtNicolas SkrypekWouter Van Loocke et al.

A1 Journal Article in CANCER RESEARCH

Vascular transcription factors guide plant epidermal responses to limiting phosphate conditions

Jos WendrichBaojun YangNiels VandammeKevin VerstaenWouter SmetCelien Van de VeldeMax MinneBrecht WybouwEliana MorHelena Arents et al.

A1 Journal Article in SCIENCE

Zeb2 drives invasive and microbiota-dependent colon carcinoma

Karolina SlowickaIoanna PettaGillian BlanckeEsther HosteEmilie DumasMozes SzeHanna-Kaisa VikkulaEnrico RadaelliJody J. HaighSven Jonckheere et al.

A1 Journal Article in NATURE CANCER

2019

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment

Hannah Van HoveLiesbet MartensIsabelle ScheyltjensKaren De VlaminckAna Rita Pombo AntunesSofie De PrijckNiels VandammeSebastiaan De SchepperGert Van IsterdaelCharlotte Scott et al.

A1 Journal Article in NATURE NEUROSCIENCE

From neural crest cells to melanocytes : cellular plasticity during development and beyond

Niels VandammeGeert Berx

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia

Gloria MilaniFilip MatthijssensWouter Van LoockeKaat DurinckJuliette RoelsSofie PeirsMorgan ThénozTim PietersLindy ReunesBéatrice Lintermans et al.

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

USP7 cooperates with NOTCH1 to drive the oncogenic transcriptional program in T-cell leukemia

Qi JinCarlos A MartinezKelly M ArcipowskiYixing ZhuBlanca T Gutierrez-DiazKenneth K WangMegan R JohnsonAndrew G VolkFeng WangJian Wu et al.

A1 Journal Article in CLINICAL CANCER RESEARCH

2018

Expressed repetitive elements are broadly applicable reference targets for normalization of reverse transcription-qPCR data in mice

Marjolijn RenardSuzanne VanhauwaertMarine VanhomwegenAli RihaniNiels VandammeSteven GoossensGeert BerxPieter Van VlierbergheJody J HaighBieke Decaesteker et al.

A1 Journal Article in SCIENTIFIC REPORTS

The TLX1 oncogene modules the enhancer RNA landscape in T-ALL

Karen VerboomWouter Van LoockeJo VandesompeleNiels VandammeGeert BerxYvan SaeysLiesbet MartensPieter Van VlierbergheFranki SpelemanKaat Durinck

The transcription factor ZEB2 is required to maintain the tissue-specific identities of macrophages

Charlotte ScottWouter T'JonckLiesbet MartensHelena TodorovDorine SichienBieke SoenJohnny BonnardelSofie De PrijckNiels VandammeRobrecht Cannoodt et al.

A1 Journal Article in IMMUNITY

TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia

Karen VerboomWouter Van LoockeJo VandesompeleNiels VandammeGeert BerxLiesbet MartensYvan SaeysPieter Van VlierbergheFranki SpelemanKaat Durinck

ZEB proteins in leukemia : friends, foes, or friendly foes?

Bieke SoenNiels VandammeGeert BerxJürg SchwallerPieter Van VlierbergheSteven Goossens

A2 Journal Article in HEMASPHERE

ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 and DNMTs during epithelial-to-mesenchymal transition

Nicolas SkrypekKenneth BruneelCindy VandewalleEva De SmedtBieke SoenNele LoretJoachim TaminauSteven GoossensNiels VandammeGeert Berx

A1 Journal Article in EPIGENETICS & CHROMATIN

2017

EMT transcription factors in cancer development re-evaluated : beyond EMT and MET

Steven GoossensNiels VandammePieter Van VlierbergheGeert Berx

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Epithelial-to-mesenchymal transition : epigenetic reprogramming driving cellular plasticity

Nicolas SkrypekSteven GoossensEva De SmedtNiels VandammeGeert Berx

A1 Journal Article in TRENDS IN GENETICS

EV-TRACK : transparent reporting and centralizing knowledge in extracellular vesicle research

Jan Van DeunPieter MestdaghPatrizia AgostinisÖzden AkaySushma AnandJasper AnckaertZoraida Andreu MartinezTine BaetensEls BegheinLaurence Bertier et al.

A1 Journal Article in NATURE METHODS

Mouse cutaneous melanoma induced by mutant BRaf arises from expansion and dedifferentiation of mature pigmented melanocytes

Corinna KohlerDavid NittnerFlorian RambowEnrico RadaelliFabio StanchiNiels VandammeArianna BaggioliniLukas SommerGeert BerxJoost J van den Oord et al.

A1 Journal Article in CELL STEM CELL

Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia

Steven GoossensSofie PeirsWouter Van LoockeJueqiong WangMina TakawyFilip MatthijssensStefan E SondereggerKatharina HaighThao NguyenNiels Vandamme et al.

A1 Journal Article in BLOOD

Structure-function studies in mouse embryonic stem cells using recombinase-mediated cassette exchange

Tim PietersLieven HaenebalckeKenneth BruneelNiels VandammeTino HochepiedJolanda van HengelDagmar WirthGeert BerxJody J HaighFrans Van Roy et al.

A1 Journal Article in JOVE-JOURNAL OF VISUALIZED EXPERIMENTS

Targeting BET proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia

Sofie PeirsV FrismantasFilip MatthijssensW Van LoockeTim PietersNiels VandammeBéatrice LintermansMP DobayGeert BerxBruce Poppe et al.

A1 Journal Article in LEUKEMIA

ZEB1 and ZEB2 dictate melanocyte differentiation and melanoma phenotype switching

Niels VandammeGeert Berx

2016

BRD4 inhibition improves the efficacy of ABT-199 in T-cell acute lymphoblastic leukemia

Sofie PeirsFilip MatthijssensTim PietersNiels VandammeGeert BerxBruce PoppePieter Van Vlierberghe

BRD4 inhibition improves the efficacy of ABT-199 in T-cell acute lymphoblastic leukemia

Sofie PeirsFilip MatthijssensTim PietersNiels VandammeGeert BerxBruce PoppePieter Van Vlierberghe

Genetic characterization and therapeutic targeting of MYC translocated pediatric T-cell acute lymphoblastic leukemia

Gloria MilaniKaat DurinckFilip MatthijssensSofie PeirsTim PietersLindy ReunesBéatrice LintermansNiels VandammeTim LammensYunlei Li et al.

Targeting BET family proteins improves the efficacy of ABT-199 in T-cell acute lymphoblastic leukemia

Sofie PeirsFilip MatthijssensBéatrice LintermansTim PietersNiels VandammeGeert BerxBruce PoppePieter Van Vlierberghe

Targeting BET family proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia

Sofie PeirsViktoras FrismantasFilip MatthijssensBéatrice LintermansTim PietersNiels VandammeWouter Van LoockeGeert BerxBruce PoppeJean-Pierre Bourquin et al.

The combination of ABT-199 and JQ1 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia

Sofie PeirsFilip MatthijssensTim PietersNiels VandammeBéatrice LintermansLindy ReunesGeert BerxBruce PoppePieter Van Vlierberghe

2015

Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection

Mary van HeldenSteven GoossensCécile DaussyAnne-Laure MathieuFabrice FaureAntoine MarçaisNiels VandammeNatalie FarlaKatia MayolSébastien Viel et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

2014

Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression

Geertrui DeneckerNiels VandammeOzden AkayD KoludrovicJoachim TaminauKelly LemeireAlexander GheldofBram De CraeneMireille Van GeleLieve Brochez et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

Melanoma cells revive an embryonic transcriptional network to dictate phenotypic heterogeneity

Niels VandammeGeert Berx

A2 Journal Article in FRONTIERS IN ONCOLOGY