Research Explorer

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Researcher

Nicolas Skrypek

Awards & Distinctions

6 Results

2024

ZEB2 drives intra-tumor heterogeneity and skin squamous cell carcinoma formation with distinct EMP transition states

Jeroen VerstappeNicolas SkrypekJordy De ConinckBieke SoenJoachim TaminauMarianthi TatariKenneth BruneelNele LoretKato De ClercqCaroline Van den Broecke et al.

A1 Journal Article in ISCIENCE

2020

The EMT transcription factor ZEB2 promotes proliferation of primary and metastatic melanoma while suppressing an invasive, mesenchymal-like phenotype

Niels VandammeGeertrui DeneckerKenneth BruneelGillian BlanckeOzden AkayJoachim TaminauJordy De ConinckEva De SmedtNicolas SkrypekWouter Van Loocke et al.

A1 Journal Article in CANCER RESEARCH

2018

ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 and DNMTs during epithelial-to-mesenchymal transition

Nicolas SkrypekKenneth BruneelCindy VandewalleEva De SmedtBieke SoenNele LoretJoachim TaminauSteven GoossensNiels VandammeGeert Berx

A1 Journal Article in EPIGENETICS & CHROMATIN

2017

Epithelial-to-mesenchymal transition : epigenetic reprogramming driving cellular plasticity

Nicolas SkrypekSteven GoossensEva De SmedtNiels VandammeGeert Berx

A1 Journal Article in TRENDS IN GENETICS

2016

The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2

Charlotte ScottBieke SoenLiesbet MartensNicolas SkrypekWouter SaelensJoachim TaminauGillian BlanckeGert Van IsterdaelDanny HuylebroeckJody Haigh et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Tissue factor induced by epithelial-mesenchymal transition triggers a procoagulant state that drives metastasis of circulating tumor cells

Morgane BourcyMeggy Suarez-CarmonaJustine LambertMarie-Emilie FrancartHélène SchroederCéline DelierneuxNicolas SkrypekErik W ThompsonGuy JérusalemGeert Berx et al.

A1 Journal Article in CANCER RESEARCH