Research Explorer

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Researcher

Nele Vanlangenakker

Awards & Distinctions

13 Results

2017

Opposing regulation and roles for PHD3 in lung dendritic cells and alveolar macrophages

Simon TavernierNele VanlangenakkerJessica VettersPeter CarmelietSophie JanssensBart Lambrecht

A1 Journal Article in JOURNAL OF LEUKOCYTE BIOLOGY

Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival

Simon TavernierFabiola OsorioLana VandersarrenJessica VettersNele VanlangenakkerGert Van IsterdaelKarl VergoteRiet De RyckeEef ParthoensLianne van de Laar et al.

A1 Journal Article in NATURE CELL BIOLOGY

2014

Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis

Quinten RemijsenVera GoossensSasker GrootjansC Van den HauteNele VanlangenakkerYves DondelingerRia RoelandtInge BruggemanAmanda GonçalvesMathieu Bertrand et al.

A1 Journal Article in CELL DEATH & DISEASE

2012

Many stimuli pull the necrotic trigger, an overview

Nele VanlangenakkerTom Vanden BerghePeter Vandenabeele

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

RIP1 is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosis

S LoederM SchirmerH SchoenebergerS CristofanonJ LeibacherNele VanlangenakkerMathieu BertrandPeter VandenabeeleI JeremiasK-M Debatin et al.

A1 Journal Article in LEUKEMIA

2011

Programmed necrosis : from molecules to health and disease

Lorenzo GalluzziTom Vanden BergheNele VanlangenakkerSabrina BuettnerTobias EisenbergPeter VandenabeeleFrank MadeoGuido Kroemer

A1 Journal Article in International Review of Cell and Molecular Biology

Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosis

Bram LaukensClaudia JenneweinBarbara SchenkNele VanlangenakkerAlexander SchierSilvia CristofanonKerry ZobelKurt DeshayesDomagoj VucicIrmela Jeremias et al.

A1 Journal Article in NEOPLASIA

TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members

Nele VanlangenakkerMathieu BertrandPieter BogaertPeter VandenabeeleTom Vanden Berghe

A1 Journal Article in CELL DEATH & DISEASE

Unraveling TNF-induced necrotic signaling pathways using RNA interference and live-cell imaging

Nele VanlangenakkerPeter VandenabeeleTom Vanden Berghe

cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production

Nele VanlangenakkerTom Vanden BerghePieter BogaertBram LaukensK ZobelK DeshayesD VucicS FuldaPeter VandenabeeleMathieu Bertrand

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

2010

Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features

Tom Vanden BergheNele VanlangenakkerEef ParthoensWies DeckersMichael DevosNele FestjensChris GuerinUT BrunkWim DeclercqPeter Vandenabeele

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

2009

Necrosis: molecular mechanisms and physiological roles

Linde DuprezNele VanlangenakkerNele FestjensFranky Van HerrewegheTom Vanden BerghePeter Vandenabeele

Bookchapter in Essentials of apoptosis : a guide for basic and clinical research

2008

Molecular mechanisms and pathophysiology of necrotic cell death

Nele VanlangenakkerTom Vanden BergheDmitri KryskoNele FestjensPeter Vandenabeele

A1 Journal Article in CURRENT MOLECULAR MEDICINE