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Researcher
Nele Festjens
Profile
Projects
Publications
Activities
Awards & Distinctions
39
Results
2023
N-glycosylation engineering in chimeric antigen receptor T cells enhances anti-tumor activity
Elien De Bousser
Nele Festjens
Leander Meuris
Evelyn Plets
Annelies Van Hecke
Elise Wyseure
Stijn De Munter
Bart Vandekerckhove
Nico Callewaert
Preprint
2023
2021
Exploration of synergistic action of cell wall-degrading enzymes against mycobacterium tuberculosis
Loes van Schie
Katlyn Borgers
Gitte Michielsen
Evelyn Plets
Marnik Vuylsteke
Petra Tiels
Nele Festjens
Nico Callewaert
A1
Journal Article
in
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
2021
Method development for the structural and functional analysis of (CAR) T cell glycome alterations
Elien De Bousser
Nico Callewaert
Nele Festjens
Dissertation
2021
Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity
Fabien Henri Thery
Lia Martina
Caroline Asselman
Heidi Repo
Y Zhang
Koen Sedeyn
Georgios Moschonas
C Bredow
QW Teo
J Zhang
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2021
T cell engaging immunotherapies, highlighting chimeric antigen receptor (CAR) T cell therapy
Elien De Bousser
Nico Callewaert
Nele Festjens
A1
Journal Article
in
CANCERS
2021
2020
Development of a counterselectable transposon to create markerless knockouts from an 18,432-clone ordered Mycobacterium bovis bacillus Calmette-Guérin mutant resource
Katlyn Borgers
Kristof Vandewalle
Annelies Van Hecke
Gitte Michielsen
Evelyn Plets
Loes van Schie
Sandrine Vanmarcke
Laurent Schindfessel
Nele Festjens
Nico Callewaert
A1
Journal Article
in
MSYSTEMS
2020
Human T cell glycosylation and implications on immune therapy for cancer
Elien De Bousser
Leander Meuris
Nico Callewaert
Nele Festjens
A1
Journal Article
in
Human Vaccines & Immunotherapeutics
2020
2019
A guide to Mycobacterium mutagenesis
Katlyn Borgers
Kristof Vandewalle
Nele Festjens
Nico Callewaert
A1
Journal Article
in
FEBS JOURNAL
2019
Development and implementation of novel genetic tools for slow-growing mycobacteria
Katlyn Borgers
Nico Callewaert
Nele Festjens
Dissertation
2019
Reference genome and comparative genome analysis for the WHO reference strain for Mycobacterium bovis BCG Danish, the present tuberculosis vaccine
Katlyn Borgers
Jheng-Yang Ou
Po-Xing Zheng
Petra Tiels
Annelies Van Hecke
Evelyn Plets
Gitte Michielsen
Nele Festjens
Nico Callewaert
Yao-Cheng Lin
A1
Journal Article
in
BMC GENOMICS
2019
SapM mutation to improve the BCG vaccine : genomic, transcriptomic and preclinical safety characterization
Nele Festjens
Kristof Vandewalle
Erica Houthuys
Evelyn Plets
Dieter Vanderschaeghe
Katlyn Borgers
Annelies Van Hecke
Petra Tiels
Nico Callewaert
A1
Journal Article
in
VACCINE
2019
2015
Building genome-wide mutant resources in slow-growing mycobacteria
Kristof Vandewalle
Nico Callewaert
Nele Festjens
Dissertation
2015
Characterization of genome-wide ordered sequence-tagged Mycobacterium mutant libraries by Cartesian Pooling-Coordinate Sequencing
Kristof Vandewalle
Nele Festjens
Evelyn Plets
Marnik Vuylsteke
Yvan Saeys
Nico Callewaert
A1
Journal Article
in
NATURE COMMUNICATIONS
2015
2014
GlycoDelete engineering of mammalian cells simplifies N-glycosylation of recombinant proteins
Leander Meuris
Francis Santens
Greg Elson
Nele Festjens
Morgane Boone
Anaëlle Dos Santos
Simon Devos
François Rousseau
Evelyn Plets
Erica Houthuys
et al.
A1
Journal Article
in
NATURE BIOTECHNOLOGY
2014
2012
Intermediate domain of receptor-interacting protein kinase 1 (RIPK1) determines switch between necroptosis and RIPK1 kinase-dependent apoptosis
Linde Duprez
Mathieu Bertrand
Tom Vanden Berghe
Yves Dondelinger
Nele Festjens
Peter Vandenabeele
A1
Journal Article
in
JOURNAL OF BIOLOGICAL CHEMISTRY
2012
2011
Disruption of the SapM locus in Mycobacterium bovis BCG improves its protective efficacy as a vaccine against M. tuberculosis
Nele Festjens
Pieter Bogaert
Anjana Batni
Erica Houthuys
Evelyn Plets
Dieter Vanderschaeghe
Bram Laukens
Bob Asselbergh
Eef Parthoens
Riet De Rycke
et al.
A1
Journal Article
in
EMBO MOLECULAR MEDICINE
2011
2010
Fed-batch fermentation of GM-CSF-producing glycoengineered Pichia pastoris under controlled specific growth rate
Pieter Jacobs
M Inan
Nele Festjens
Jurgen Haustraete
Annelies Van Hecke
Roland Contreras
MM Meagher
Nico Callewaert
A1
Journal Article
in
MICROBIAL CELL FACTORIES
2010
Glycome profiling using modern glycomics technology: technical aspects and applications
Dieter Vanderschaeghe
Nele Festjens
Joris Delanghe
Nico Callewaert
A1
Journal Article
in
BIOLOGICAL CHEMISTRY
2010
Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features
Tom Vanden Berghe
Nele Vanlangenakker
Eef Parthoens
Wies Deckers
Michael Devos
Nele Festjens
Chris Guerin
UT Brunk
Wim Declercq
Peter Vandenabeele
A1
Journal Article
in
CELL DEATH AND DIFFERENTIATION
2010
The mitochondrial serine protease HtrA2/Omi cleaves RIP1 during apoptosis of Ba/F3 cells induced by growth factor withdrawal
Lieselotte Vande Walle
Ellen Wirawan
Mohamed Lamkanfi
Nele Festjens
Jelle Verspurten
Xavier Saelens
Tom Vanden Berghe
Peter Vandenabeele
A1
Journal Article
in
CELL RESEARCH
2010
Tumor necrosis factor-mediated cell death: to break or to burst, that's the question
Franky Van Herreweghe
Nele Festjens
Wim Declercq
Peter Vandenabeele
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2010
2009
Necrosis: molecular mechanisms and physiological roles
Linde Duprez
Nele Vanlangenakker
Nele Festjens
Franky Van Herreweghe
Tom Vanden Berghe
Peter Vandenabeele
Bookchapter
in
Essentials of apoptosis : a guide for basic and clinical research
2009
2008
Molecular mechanisms and pathophysiology of necrotic cell death
Nele Vanlangenakker
Tom Vanden Berghe
Dmitri Krysko
Nele Festjens
Peter Vandenabeele
A1
Journal Article
in
CURRENT MOLECULAR MEDICINE
2008
2007
Caspases in cell survival, proliferation and differentiation
Mohamed Lamkanfi
Nele Festjens
Wim Declercq
Tom Vanden Berghe
Peter Vandenabeele
A1
Journal Article
in
CELL DEATH AND DIFFERENTIATION
2007
Inflammatory caspases : targets for novel therapies
Sigrid Cornelis
Kristof Kersse
Nele Festjens
Mohamed Lamkanfi
Peter Vandenabeele
A1
Journal Article
in
CURRENT PHARMACEUTICAL DESIGN
2007
RIP1, a kinase on the crossroads of a cell's decision to live or die
Nele Festjens
Tom Vanden Berghe
Sigrid Cornelis
Peter Vandenabeele
A1
Journal Article
in
CELL DEATH AND DIFFERENTIATION
2007
The caspase-generated fragments of PKR cooperate to activate full-length PKR and inhibit translation
Michaël Kalai
V SUIN
Nele Festjens
Ann Meeus
A BERNIS
XM WANG
Xavier Saelens
Peter Vandenabeele
A1
Journal Article
in
CELL DEATH AND DIFFERENTIATION
2007
2006
Butylated hydroxyanisole is more than a reactive oxygen species scavenger
Nele Festjens
Michaël Kalai
Joél Smet
Ann Meeus
Rudy Van Coster
Xavier Saelens
Peter Vandenabeele
A1
Journal Article
in
CELL DEATH AND DIFFERENTIATION
2006
Caspase inhibitors promote alternative cell death pathways
Peter Vandenabeele
Tom Vanden Berghe
Nele Festjens
A4
Journal Article
in
Science Signal Transduction Knowledge Environment
2006
Caspase-containing complexes in the regulation of cell death and inflammation
Nele Festjens
Sigrid Cornelis
Mohamed Lamkanfi
Peter Vandenabeele
A1
Journal Article
in
BIOLOGICAL CHEMISTRY
2006
Macrophages use different internalization mechanisms to clear apoptotic and necrotic cells
Dmitri Krysko
Geertrui Denecker
Nele Festjens
Sofie Gabriëls
Eef Parthoens
Katharina D'Herde
Peter Vandenabeele
A1
Journal Article
in
CELL DEATH AND DIFFERENTIATION
2006
Necrosis, a well-orchestrated form of cell demise: Signalling cascades, important mediators and concomitant immune response
Nele Festjens
Tom Vanden Berghe
Peter Vandenabeele
A1
Journal Article
in
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
2006
Role of mitochondrial proteins in apoptosis.
Xavier Saelens
Nele Festjens
Lieselotte Vande Walle
Peter Vandenabeele
Bookchapter
in
Apoptosis and cancer therapy
2006
2005
Fas induced necrosis.
Tom Vanden Berghe
Nele Festjens
Michaël Kalai
Xavier Saelens
Peter Vandenabeele
Bookchapter
in
Fas Signaling
2005
Mitochondria: Breathe or die
Lieselotte Vande Walle
Nele Festjens
Xavier Saelens
Peter Vandenabeele
Bookchapter
in
Apoptosis
2005
Protein synthesis persists during necrotic cell death
Xavier Saelens
Nele Festjens
Eef Parthoens
Isabel Vanoverberghe
Michaël Kalai
F VAN KUPPEVELD
Peter Vandenabeele
A1
Journal Article
in
JOURNAL OF CELL BIOLOGY
2005
2004
Toxic proteins released from mitochondria in cell death
Xavier Saelens
Nele Festjens
Lieselotte Vande Walle
Maria (Marjan) van Gurp
Geert van Loo
Peter Vandenabeele
A1
Journal Article
in
ONCOGENE
2004
2003
Bcl-2 family members as sentinels of cellular integrity and role of mitochondrial intermembrane space proteins in apoptotic cell death
Nele Festjens
Maria (Marjan) van Gurp
Geert van Loo
Xavier Saelens
Peter Vandenabeele
A1
Journal Article
in
ACTA HAEMATOLOGICA
2003
Mitochondrial intermembrane proteins in cell death
Maria (Marjan) van Gurp
Nele Festjens
Geert van Loo
Xavier Saelens
Peter Vandenabeele
A1
Journal Article
in
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
2003