Research Explorer

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Researcher

Nadine Van Roy

304 Results

2023

High-grade endometrial stromal sarcoma-like sarcoma in male : does it exist? A case report and review of the literature

Fleur CordierJoni Van der MeulenSiebe LoontiensNadine Van RoyLore LapeireWouter WillaertLiesbeth FerdinandeKoen Van de VijverJo Van DorpeDavid Creytens

A1 Journal Article in PATHOLOGY RESEARCH AND PRACTICE

SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry

Bieke DecaestekerAmber LouwagieSiebe LoontiensFanny De VloedSarah-Lee BekaertJuliette RoelsSuzanne VanhauwaertSara De BrouwerEllen SandersA Berezovskaya et al.

A1 Journal Article in NATURE COMMUNICATIONS

2022

Extrauterine mesonephric-like neoplasms : expanding the morphologic spectrum

Ellen DeoletIteeka AroraJo Van DorpeJoni Van der MeulenSudha DesaiNadine Van RoyBaljeet KaurKoen Van de VijverW Glenn McCluggage

A1 Journal Article in AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Malignant pleural mesothelioma with an EML4-ALK fusion : expect the unexpected!

Fleur CordierJoni Van der MeulenNadine Van RoyJilke De WildeHerwig van DijckFilip VanhoenackerMarc LambrechtsValentin NoyezKoen Van de VijverLiesbeth Ferdinande et al.

A1 Journal Article in PATHOLOGY RESEARCH AND PRACTICE

Shallow whole-genome sequencing : a useful, easy to apply molecular technique for CNA detection on FFPE tumor tissue : a glioma-driven study

Kim Van der EeckenMalaïka Van der LindenLennart RamanDavid CreytensFranceska DedeurwaerdereKoen De WinneLiesbeth FerdinandeMartin LammensBjörn MentenIsabelle Rottiers et al.

A1 Journal Article in VIRCHOWS ARCHIV

Targeted therapy in juvenile myelomonocytic leukemia : where are we now?

Nele De VosMattias HofmansTim LammensBram De WildeNadine Van RoyBarbara De Moerloose

A1 Journal Article in PEDIATRIC BLOOD & CANCER

The feasibility of using liquid biopsies as a complementary assay for copy number aberration profiling in routinely collected paediatric cancer patient samples

Ruben Van PaemelCharlotte VandeputteLennart RamanJolien Van ThorreLeen WillemsJo Van DorpeMalaïka Van der LindenJilke De WildeAndries De KokerBjörn Menten et al.

A1 Journal Article in EUROPEAN JOURNAL OF CANCER

2021

Association of unbalanced translocation der(1;7) with germline GATA2 mutations

Emilia J. KozyraGudrun GoehringDennis D. HicksteinKatherine R. CalvoCourtney D. DiNardoMichael DworzakValerie de HaasJan StaryHenrik HasleAkiko Shimamura et al.

A1 Journal Article in BLOOD

Development of chronic myeloid leukemia in a patient previously diagnosed with a JAK2-positive myeloproliferative neoplasm

Sander De BruyneEVA STEELMarjan PetrickBarbara DenysKarl VandepoeleNadine Van RoySimon DegandtTimothy GhysHenk Louagie

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Frequency and prognostic impact of ALK amplifications and mutations in the European Neuroblastoma Study Group (SIOPEN) high-risk neuroblastoma trial (HR-NBL1)

Angela BelliniUlrike PötschgerVirginie BernardEve LapoubleSylvain BaulandePeter F. AmbrosNathalie AugerKlaus BeiskeMarie BernkopfDavid R. Betts et al.

A1 Journal Article in JOURNAL OF CLINICAL ONCOLOGY

From DNA copy number gains and tumor dependencies to novel therapeutic targets for high-risk neuroblastoma

Bieke DecaestekerKaat DurinckNadine Van RoyBram De WildeChristophe Van NesteStéphane Van HaverStephen RobertsKatleen De PreterVanessa VermeirssenFranki Speleman

A1 Journal Article in JOURNAL OF PERSONALIZED MEDICINE

Malignant pleural mesothelioma with an EML4-ALK fusion : expect the unexpected!

Fleur CordierJoni Van der MeulenNadine Van RoyHerwig Van DijckFilip VanhoenackerMarc LambrechtsValentin NoyezLiesbeth FerdinandeAmélie DendoovenJo Van Dorpe et al.

Minimally invasive classification of pediatric solid tumors using reduced representation bisulfite sequencing of cell-free DNA : a proof-of-principle study

Ruben Van PaemelAndries De KokerCharlotte VandeputteLieke van ZogchelTim LammensGenevieve LaureysJo VandesompeleGudrun SchleiermacherMathieu ChicardNadine Van Roy et al.

A1 Journal Article in EPIGENETICS

SOX11 as guardian of epigenetic plasticity in neuroblastoma

Bieke DecaestekerAmber LouwagieSiebe LoontiensSara De BrouwerCarolina de Carvalho NunesGeertrui DeneckerFanny De VloedLisa DepestelJuliette RoelsKaren Verboom et al.

2020

A challenging diagnosis of a nonsecretor plasma cell dyscrasia with pleomorphic plasmablastic morphology

Stijn Van LandeghemSara CapiauJean‐Louis BayartPhilip VlummensJo Van DorpeNadine Van RoyJan Philippé

A2 Journal Article in CLINICAL CASE REPORTS

Detection of copy number alterations by shallow whole-genome sequencing of formalin-fixed, paraffin-embedded tumor tissue

Malaïka Van der LindenLennart RamanAnsel Vander TrappenAnnelies DheedeneMatthias De SmetTom SanteDavid CreytensYolande LievensBjörn MentenJo Van Dorpe et al.

A1 Journal Article in ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Minimally invasive classification of pediatric solid tumors using reduced representation bisulfite sequencing of cell-free DNA

Ruben Van PaemelAndries De KokerCharlotte VandeputteLieke Van ZogchelTim LammensGenevieve LaureysJo VandesompeleGudrun SchleiermacherMatthieu ChicardNadine Van Roy et al.

Retrospective analysis of the incidence and characteristics of paediatric myelodysplastic syndrome and juvenile myelomonocytic leukaemia in Belgium

Lindsey De SmaeleMattias HofmansTim LammensA Van DammeJutte van der Werff ten BoschA FersterJoris VerlooyC ChantrainJan PhilippéNadine Van Roy et al.

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

Renate De SmedtJulie MorscioLindy ReunesJuliette RoelsValentina BardelliBéatrice LintermansWouter Van LoockeAfonso AlmeidaLaurence C. CheungRishi S. Kotecha et al.

A1 Journal Article in BLOOD

The pitfalls and promise of liquid biopsies for diagnosing and treating solid tumors in children : a review

Ruben Van PaemelROSALIE VLUGKatleen De PreterNadine Van RoyFranki SpelemanLeen WillemsTim LammensGenevieve LaureysGudrun SchleiermacherGodelieve AM Tytgat et al.

A1 Journal Article in EUROPEAN JOURNAL OF PEDIATRICS

2019

A case report of acute panmyelosis with myelofibRosis (APMF) with a distinct molecular pattern

Emilie De MaertelaereKarl VandepoeleJoni Van der MeulenIne MoorsWillem DaneelsAnke DelieJan PhilippéCarolien BonroyKatrien DevreeseNadine Van Roy et al.

Clinical experience with shallow whole genome sequencing as a detection method for Copy Number Variations

Björn MentenMaarten De SmetLennart RamanTom SanteNadine Van RoyAnnelies Dheedene

Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia

Gloria MilaniFilip MatthijssensWouter Van LoockeKaat DurinckJuliette RoelsSofie PeirsMorgan ThénozTim PietersLindy ReunesBéatrice Lintermans et al.

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Minimally invasive classification of pediatric solid tumors using reduced representation bisulfite sequencing of cell-free DNA : a proof-of-principle study

Ruben Van PaemelAndries De KokerCharlotte VandeputteLieke van ZogchelTim LammensGenevieve LaureysJo VandesompeleGudrun SchleiermacherMathieu ChicardNadine Van Roy et al.

Non-invasive classification of pediatric tumor types using reduced representation bisulfite sequencing of cell-free DNA : a proof-of-principle study

Ruben Van PaemelA. De KokerCharlotte VandeputteL. M. J. van ZogchelM. ChicardTim LammensJo VandesompeleNadine Van RoyG. SchleiermacherG. A. M. Tytgat et al.

Noonan syndrome-associated myeloproliferative disorder with somatically acquired monosomy 7 : impact on clinical decision making

Mattias HofmansRieke SchroederTim LammensChristian FlothoCharlotte NiemeyerNadine Van RoyWim DecaluweJan PhilippéBarbara De Moerloose

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Pinpointing a potential role for CLEC12B in cancer predisposition through familial exome sequencing

Charlotte DerpoorterKarl VandepoeleAraceli Diez FraileKatrien VandemeulebroeckeBram De WildeFranki SpelemanNadine Van RoyTim LammensGenevieve Laureys

A1 Journal Article in PEDIATRIC BLOOD & CANCER

SOX11 as mediator of the adrenergic cell state in NB

Bieke DecaestekerAmber LouwagieSara De BrouwerVolodimir OlexioukGeertrui DeneckerCarolina de Carvalho NunesKaren VerboomMoritz GartlgruberWouter Van LoockeElena Afanasyeva et al.

SOX11 is a key epigenetic regulator in the adrenergic MYCN amplified neuroblastoma

Amber LouwagieBieke DecaestekerCarolina de Carvalho NunesGeertrui DeneckerVolodimir OlexioukKaren VerboomMoritz GartlgruberWouter Van LoockeElena AfanasyevaPauline Depuydt et al.

SOX11 is a key epigenetic regulator in the adrenergic MYCN amplified neuroblastoma

Amber LouwagieBieke DecaestekerSara De BrouwerGeertrui DeneckerCarolina de Carvalho NunesVolodimir OlexioukKaren VerboomMoritz GartlgruberWouter Van LoockeElena Afanasyeva et al.

Shallow whole genome sequencing on circulating cell-free DNA in pediatric cancer patients

Charlotte VandeputteJolien Van ThorreRuben Van PaemelAndries De KokerLeen WillemsJo Van DorpeMalaïka Van der LindenJilke De WildeBjörn MentenL. van Zogchel et al.

Shallow whole genome sequencing on circulating cell-free DNA in pediatric cancer patients

Charlotte VandeputteJolien Van ThorreRuben Van PaemelAndries De KokerLeen WillemsJo Van DorpeMalaïka Van der LindenJilke De WildeBjörn MentenLieke van Zogchel et al.

Shallow whole genome sequencing on circulating cell-free DNA in pediatric cancer patients

Charlotte VandeputteJolien Van ThorreRuben Van PaemelAndries De KokerLeen WillemsJo Van DorpeMalaïka Van der LindenJilke De WildeBjörn MentenLieke van Zogchel et al.

Successful copy number alteration profiling using circulating cell-free tumor DNA as a non-invasive alternative for tissue biopsies in pediatric cancer patients

Charlotte VandeputteJolien Van ThorreRuben Van PaemelAndries De KokerLeen WillemsJo Van DorpeMalaïka Van der LindenJilke De WildeBjörn MentenLieke van Zogchel et al.

2018

A case of chronic eosinophilic leukemia with secondary transformation to acute myeloid leukemia

Mattias HofmansAnke DelieKarl VandepoeleNadine Van RoyJoni Van der MeulenJan PhilippéIne Moors

A2 Journal Article in LEUKEMIA RESEARCH REPORTS

Detection of copy number alterations using shallow whole genome sequencing on formalin-fixed paraffin-embedded tumor tissue

Malaïka Van der LindenLennart RamanAnsel Vander TrappenAnnelies DheedeneMatthias De SmetTom SanteDavid CreytensBjörn MentenJo Van DorpeNadine Van Roy

Detection of copy number alterations using shallow whole genome sequencing on formalin-fixed paraffin-embedded tumor tissue

Malaïka Van der LindenLennart RamanAnsel Vander TrappenAnnelies DheedeneMatthias De SmetTom SanteDavid CreytensBjörn MentenJo Van DorpeNadine Van Roy

Differential impact of drugs on the outcome of ETV6-RUNX1 positive childhood B-cell precursor acute lymphoblastic leukaemia : results of the EORTC CLG 58881 and 58951 trials

C PietteS SuciuE ClappierY BertrandS DrunatS GirardK YakoubenG PlatN DastugueF Mazingue et al.

A1 Journal Article in LEUKEMIA

Exploring the long non-coding RNA landscape in juvenile myelomonocytic leukemia

Mattias HofmansTim LammensS BresolinH CavéC FlothoH HasleHetty HelsmoortelM Van den Heuvel-EibrinkC NiemeyerJ Stary et al.

Non-invasive differential diagnosis of neuroblastoma with other paediatric solid tumors using methylation profiling of circulating cell-free DNA

Ruben Van PaemelAnneleen DecockCharlotte VandeputteTim LammensGenevieve LaureysFranki SpelemanWim Van CriekingeNadine Van RoyJo VandesompeleKatleen De Preter et al.

Non-invasive differential diagnosis of neuroblastoma with other paediatric solid tumors using methylation profiling of circulating cell-free DNA

Ruben Van PaemelAnneleen DecockCharlotte VandeputteTim LammensGenevieve LaureysFranki SpelemanWim Van CriekingeNadine Van RoyJo VandesompeleKatleen De Preter et al.

Non-invasive differential diagnosis of neuroblastoma with other paediatric solid tumors using methylation profiling of circulating cell-free DNA

Ruben Van PaemelAnneleen DecockCharlotte VandeputteTim LammensGenevieve LaureysFranki SpelemanWim Van CriekingeNadine Van RoyJo VandesompeleKatleen De Preter et al.

Pre-clinical evaluation of second generation PIM inhibitors for the treatment of T-cell acute lymphoblastic leukemia and lymphoma

Renate De SmedtSofie PeirsJulie MorscioFilip MatthijssensJuliette RoelsLindy ReunesBéatrice LintermansSteven GoossensTim LammensNadine Van Roy et al.

A1 Journal Article in HAEMATOLOGICA

Shallow whole genome sequencing allows successful copy number profiling in formalin-fixed paraffin-embedded material in neuroblastoma patients

Charlotte VandeputteRuben Van PaemelBram De WildeMalaïka Van der LindenJo Van DorpeBjörn MentenFranki SpelemanNadine Van RoyKatleen De Preter

The long non-coding RNA landscape in juvenile myelomonocytic leukemia

Mattias HofmansTim LammensHetty HelsmoortelSilvia BresolinHélène CavéChristian FlothoHenrik HasleMarry M van den Heuvel-EibrinkCharlotte NiemeyerJan Stary et al.

A1 Journal Article in HAEMATOLOGICA

The potential of methylome sequencing in the diagnostic work : up of pediatric solid tumors

Ruben Van PaemelCharlotte VandeputteBram De WildeKatleen De PreterNadine Van RoyJo VandesompeleTim LammensWim Van CriekingeP. UltzNico Callewaert et al.

2017

'Atypical' pleomorphic lipomatous tumor : a clinicopathologic, immunohistochemical and molecular study of 21 cases, emphasizing its relationship to atypical spindle cell lipomatous tumor and suggesting a morphologic spectrum (atypical spindle cell/pleomorphic lipomatous tumor)

David CreytensThomas MentzelLiesbeth FerdinandeEvelyne LecoutereJoost van GorpLilit AtanesyanKarel de GrootSuvi SavolaNadine Van RoyJo Van Dorpe et al.

A1 Journal Article in AMERICAN JOURNAL OF SURGICAL PATHOLOGY

A JAK3/STAT3 passenger activation in a lapatinib-acquired resistance model of HER2-amplified breast cancer

Mieke Van BockstalNadine Van RoyGlenn VergauwenKathleen LambeinVeronique CocquytLouis LibbrechtHannelore DenysMarc BrackeOlivier De Wever

A case report of a paediatric early T-cell precursor lymphoblastic leukemia

ANNE-SOPHIE DE KONINCKCatharina DhoogeBarbara DenysKarl VandepoeleNadine Van RoyMattias HofmansJan Philippé

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

EV-TRACK : transparent reporting and centralizing knowledge in extracellular vesicle research

Jan Van DeunPieter MestdaghPatrizia AgostinisÖzden AkaySushma AnandJasper AnckaertZoraida Andreu MartinezTine BaetensEls BegheinLaurence Bertier et al.

A1 Journal Article in NATURE METHODS

Exome sequencing to identify novel neuroblastoma predisposition genes

Charlotte DerpoorterKarl VandepoeleAraceli Diez FraileKatrien VandemeulebroeckeNadine Van RoyBram De WildeTim LammensGenevieve Laureys

In-house developed 15-gene sequencing panel for acute myeloid leukemia and myelodysplasia allows robust detection of genetic defects including FLT3-ITD and CEBPA mutations

Joni Van der MeulenBarbara DenysElien De LatterSteve LefeverToon RosseelWouter SteyaertGRETA VAN DER CRUYSSENIsabelle RottiersDavid CreytensJo Van Dorpe et al.

In-house developed 15-gene sequencing panel for acute myeloid leukemia and myelodysplasia allows robust detection of genetic defects including FLT3-ITD and CEBPA mutations

Joni Van der MeulenBarbara DenysElien De LatterSteve LefeverToon RosseelWouter SteyaertGRETA VAN DER CRUYSSENIsabelle RottiersDavid CreytensJo Van Dorpe et al.

Optimizing a workflow for transcriptome analysis of CTCs isolated from venous blood

Charlotte VandeputteAnnouck PhilippronNadine Van RoyPiet PattynKatleen De Preter

Optimizing a workflow for transcriptome analysis of CTCs isolated from venous blood

Annouck PhilippronCharlotte VandeputteNadine Van RoyPiet PattynKatleen De Preter

Physical mapping of genes on plant chromosomes

Ilia KirovNadine Van RoyKatrijn Van LaereLudmila I Khrustaleva

Second hit landscape in BRCA-associated breast cancer

Mattias Van HeetveldeMieke Van BockstalTrees LepezSteve LefeverLeen PietersKathleen LambeinMarleen PraetIvo Van Den BergheFrauke CoppietersNadine Van Roy et al.

Shallow whole genome sequencing on circulating cell-free DNA allows reliable non-invasive copy number profiling in neuroblastoma patients

Nadine Van RoyMalaïka Van der LindenPauline DepuydtBjörn MentenAnnelies DheedeneCharlotte VandeputteJo Van DorpeGenevieve LaureysMarjolijn RenardTom Sante et al.

Shallow whole genome sequencing on circulating cell-free DNA allows reliable noninvasive copy-number profiling in neuroblastoma patients

Nadine Van RoyMalaïka Van der LindenBjörn MentenAnnelies DheedeneCharlotte VandeputteJo Van DorpeGenevieve LaureysMarleen RenardTom SanteTim Lammens et al.

A1 Journal Article in CLINICAL CANCER RESEARCH

The ETV5 oncogene is a target of activated ALK signaling in neuroblastoma

Liselot MusIrina LambertzCandy KumpsShana ClaeysGeertrui DeneckerWouter Van LoockeChristophe Van NesteJan KosterRogier VersteegNadine Van Roy et al.

The ETV5 oncogene is a target of activated ALK signaling in neuroblastoma

Liselot MusIrina LambertzCandy KumpsShana ClaeysGeertrui DeneckerWouter Van LoockeChristophe Van NesteJan KosterRogier VersteegNadine Van Roy et al.

The ETV5 oncogene is a target of activated ALK signaling in neuroblastoma

Liselot MusIrina LambertzCandy KumpsShana ClaeysGeertrui DeneckerWouter Van LoockeChristophe Van NesteJan KosterRogier VersteegNadine Van Roy et al.

Thermodynamic framework to assess low abundance DNA mutation detection by hybridization

Hanny WillemsAn JacobsWahyu Wijaya HadiwikartaTom VenkenDirk ValkenborgNadine Van RoyJo VandesompeleJef Hooyberghs

A1 Journal Article in PLOS ONE

2016

Detection of copy number aberrations in cell free DNA from plasma of neuroblastoma patients using shallow massive parallel sequencing

Katleen De PreterNadine Van RoyBjörn MentenAnnelies DheedeneGenevieve LaureysBram De WildeFranki Speleman

ETV5 functionally connect ALK and CXCR4 signaling in neuroblastoma

Irina LambertzShana ClaeysCandy KumpsLiselot MusEls JanssensNadine Van RoyBram De WildeGenevieve LaureysJan CoolsOlivier De Wever et al.

Expanding the TLX1 regulome in T-cell acute lymphoblastic leukemia towards long noncoding RNAs

Kaat DurinckWouter Van LoockeInge Van de WalleJoni Van der MeulenPieter-Jan VoldersNadine Van RoyYves BenoitBruce PoppePieter MestdaghJo Vandesompele et al.

LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19

Hetty HelsmoortelBarbara De MoerlooseTim PietersFarzaneh GhazaviSilvia BresolinHelene CaveAndrica de VriesValerie de HaasChristian FlothoVeerle Labarque et al.

A1 Journal Article in HAEMATOLOGICA

LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia

Hetty HelsmoortelSilvia BresolinTim LammensHélène CavéPeter NoellkeAurélie CayeFarzaneh GhazaviAndrica de VriesHenrik HasleVeerle Labarque et al.

A1 Journal Article in BLOOD

Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma

Anneleen DecockMaté OngenaertRobrecht CannoodtKimberly VerniersBram De WildeGenevieve LaureysNadine Van RoyAna Pilar BerbegallJulie Bienertova-VaskuNick Bown et al.

Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma

Anneleen DecockMaté OngenaertRobrecht CannoodtKimberly VerniersBram De WildeGenevieve LaureysNadine Van RoyAna Pilar BerbegallJulie Bienertova-VaskuNick Bown et al.

A1 Journal Article in ONCOTARGET

Monosomy 22 and partial loss of INI1 expression in a biphasic synovial sarcoma with an Ewing sarcoma-like poorly differentiated component : report of a case

Jasper BruyneelJo Van DorpeMarleen PraetBART MATTHYSNadine Van RoyLiesbeth FerdinandeDavid Creytens

A1 Journal Article in PATHOLOGY RESEARCH AND PRACTICE

Sensing mutant ALK: Capicua and ETV5 as executors of aberrant ALK-driven MAPK signaling

Irina LambertzLiselot MusCandy KumpsShana ClaeysWouter Van LoockeChristophe Van NesteJan KosterRogier VersteegNadine Van RoyBram De Wilde et al.

The BRIP1/FANCJ DNA helicase is a druggable 17q driver oncogene involved in G-quadruplex induced replicative stress resistance in neuroblastoma

Suzanne VanhauwaertAnnelies FieuwCarina LeonelliBieke DecaestekerJolien De WynPauline DepuydtSara De BrouwerNadine Van RoyShuning HeThomas Look et al.

The T-ALL oncogene TLX1 controls enhancer lncRNA expression

Karen VerboomKaat DurinckWouter Van LoockeFilip MatthijssensInge Van de WalleAnnelynn WallaertPieter-Jan VoldersNadine Van RoyYves BenoitBruce Poppe et al.

The challenging differential diagnosis of skin tumours with a rhabdoid phenotype: not all tumours with rhabdoid phenotype belong to the group of SMARCB1-deficient tumours

Jo Van DorpeAnne HoorensNadine Van RoyFranceska DedeurwaerdereDavid Creytens

A1 Journal Article in HISTOPATHOLOGY

Thorough second hit analysis in BRCA1/2 associated breast cancer

Mattias Van HeetveldeTrees LepezLeen PietersSteve LefeverJo Van DorpeKathleen LambeinMarleen Praetivo Van Den BergheFrauke CoppietersJo Vandesompele et al.

Thorough second-hit analysis in BRCA1/2-associated breast cancer

Mattias Van HeetveldeTrees LepezLeen PietersSteve LefeverJo Van DorpeKathleen LambeinMarleen PraetIvo Van Den BergheFrauke CoppietersJo Vandesompele et al.

Towards a FISH-based karyotype of Rosa L. (Rosaceae)

Ilya V KirovKatrijn Van LaereNadine Van RoyLudmila I Khrustaleva

A1 Journal Article in COMPARATIVE CYTOGENETICS

Unique long non-coding RNA expression signature in ETV6/RUNX1-Driven B-cell precursor acute lymphoblastic leukemia

Farzaneh GhazaviBarbara De MoerlooseWouter Van LoockeAnnelynn WallaertAlina FersterMarleen BakkusGeneviève PlatEric DelabesseAnne UyttebroeckFilip Van Nieuwerburgh et al.

Unique long non-coding RNA expression signature in ETV6/RUNX1-driven B-cell precursor acute lymphoblastic leukemia

Farzaneh GhazaviBarbara De MoerlooseWouter Van LoockeAnnelynn WallaertHetty HelsmoortelAlina FersterMarleen BakkusGeneviève PlatEric DelabesseAnne Uyttebroeck et al.

A1 Journal Article in ONCOTARGET

2015

CD200/BTLA deletions in pediatric precursor B-cell acute lymphoblastic leukemia treated according to the EORTC-CLG 58951 protocol

Farzaneh GhazaviEmmanuelle ClappierTim LammensStefan SuciuAurélie CayeSamira ZegrariMarleen BakkusNathalie GrardelYves BenoitOdile Minckes et al.

A1 Journal Article in HAEMATOLOGICA

Characterization of the genome-wide TLX1 binding profile in T-cell acute lymphoblastic leukemia

Kaat DurinckWouter Van LoockeJoni Van der MeulenInge Van de WalleMaté OngenaertPieter RondouAnnelynn WallaertCE de BockNadine Van RoyBruce Poppe et al.

A1 Journal Article in LEUKEMIA

ETV5 functionally connect ALK and RET signaling in neuroblastoma

Irina LambertzShana ClaeysCandy KumpsLiselot MusAnneleen BeckersEls JanssensNadine Van RoyGenevieve LaureysJohannes SchulteOlivier De Wever et al.

Focus on 16p13.3 Locus in colon cancer

Evi MampaeyAnnelies FieuwThalia Van LaethemLiesbeth FerdinandeKathleen ClaesWim CeelenYves Van NieuwenhovePiet PattynMarc De ManKim De Ruyck et al.

A1 Journal Article in PLOS ONE

Heterogeneous cytogenetic subgroups and outcomes in childhood acute megakaryoblastic leukemia: a retrospective international study

Hiroto InabaYinmei ZhouOusama AblaSouichi AdachiAnne AuvrignonH Berna BeverlooEveline de BontTai-Tsung ChangUrsula CreutzigMichael Dworzak et al.

A1 Journal Article in BLOOD

In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis

Stijn VanheeKatrien De MulderYasmine Van CaeneghemGreet VerstichelNadine Van RoyBjörn MentenImke VelgheJan PhilippéDominique De BleserBart Lambrecht et al.

A1 Journal Article in HAEMATOLOGICA

Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma

Anneleen DecockMaté OngenaertRobrecht CannoodtKimberly VerniersBram De WildeGenevieve LaureysNadine Van RoyAna Pilar BerbegallJulie Bienertova-VaskuNick Bown et al.

MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia

Evelien MetsJoni Van der MeulenGert Van PeerMichael BoicePieter MestdaghInge Van de WalleTim LammensSteven GoossensBarbara De MoerlooseYves Benoit et al.

A1 Journal Article in LEUKEMIA

Molecular basis and clinical significance of genetic aberrations in B-cell precursor acute lymphoblastic leukemia

Farzaneh GhazaviTim LammensNadine Van RoyBruce PoppeFranki SpelemanYves BenoitPieter Van VlierbergheBarbara De Moerloose

A1 Journal Article in EXPERIMENTAL HEMATOLOGY

Novel biological insights in T-cell acute lymphoblastic leukemia

Kaat DurinckSteven GoossensSofie PeirsAnnelynn WallaertWouter Van LoockeFilip MatthijssensTim PietersGloria MilaniTim LammensPieter Rondou et al.

A1 Journal Article in EXPERIMENTAL HEMATOLOGY

Somatic genetic and epigenetic architecture of myelodysplastic syndromes arising from GATA2 deficiency

Victor Bengt Pastor LoyolaShinsuke HirabayashiSandra PohlEmilia J KozyraAlbert CatalaBarbara De MoerlooseMarek DworzakHenrik HasleRiccardo MasettiMarkus Schmugge et al.

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

Joni Van der MeulenViraj SanghviKonstantinos MavrakisKaat DurinckFang FangFilip MatthijssensPieter RondouMonica RosenTim PietersPeter Vandenberghe et al.

A1 Journal Article in BLOOD

Upregulation of MAPK negative feedback regulators and RET in mutant ALK neuroblastoma : implications for targeted treatment

Irina LambertzCandy KumpsShana ClaeysSven LindnerAnneleen BeckersEls JanssensDaniel CarterAlex CazesBelamy CheungMarilena De Mariano et al.

Upregulation of MAPK negative feedback regulators and RET in mutant ALK neuroblastoma : implications for targeted treatment

Irina LambertzCandy KumpsShana ClaeysSven LindnerAnneleen BeckersEls JanssensDaniel R CarterAlex CazesBelamy B CheungMarilena De Mariano et al.

A1 Journal Article in CLINICAL CANCER RESEARCH

Upregulation of MAPK negative feedback regulators and RET in mutant ALK neuroblastoma : implications for targeted treatment

Irina LambertzCandy KumpsShana ClaeysSven LindnerAnneleen BeckersEls JanssensDaniel CarterAlex CazesBelamy CheungMarilena De Mariano et al.

Upregulation of MAPK negative feedback regulators and RET in mutant ALK neuroblastoma : implications for targeted treatment

Irina LambertzCandy KumpsShana ClaeysSven LindnerAnneleen BeckersEls JanssensDaniel CarterAlex CazesBelamy CheungMarilena De Mariano et al.

ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling

Steven GoossensEnrico RadaelliOdile BlanchetKaat DurinckJoni Van der MeulenSofie PeirsTom TaghonCedric S TremblayMagdaline CostaMorvarid Farhang Ghahremani et al.

A1 Journal Article in NATURE COMMUNICATIONS

2014

Anchoring linkage groups of the Rosa genetic map to physical chromosomes with tyramide-FISH and EST-SNP markers

Ilya KirovKatrijn Van LaereJan De RiekEllen De KeyserNadine Van RoyLudmila Khrustaleve

A1 Journal Article in PLOS ONE

Array-based comparative genomic hybridisation analysis of a pleomorphic myxoid liposarcoma

David CreytensJoost van GorpLiesbeth FerdinandeNadine Van RoyLouis Libbrecht

A1 Journal Article in JOURNAL OF CLINICAL PATHOLOGY

Characterization of ALK driven molecular networks identifies perturbed RET and cholinergic signaling in neuroblastoma

Irina LambertzCandy KumpsShana ClaeysSven LindlerAnneleen BeckersEls JanssensMarilena De MarianoSara De BrouwerJay GibbonsGenevieve Laureys et al.

Genetisch geïnspireerde toekomstperspectieven voor de therapie van het neuroblastoom

Bram De WildeTom Van MaerkenKatleen De PreterNadine Van RoyGenevieve LaureysJo VandesompeleFranki Speleman

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations

Yao-Cheng LinMorgane BooneLeander MeurisIrma LemmensNadine Van RoyArne SoeteJoke ReumersMatthieu MoisseStéphane PlaisanceRadoje Drmanac et al.

A1 Journal Article in NATURE COMMUNICATIONS

Identification of histone H3 clipping activity in human embryonic stem cells

Liesbeth VossaertPaulien MeertEllen ScheerlinckPieter GlibertNadine Van RoyBjörn HeindryckxPetra De SutterMaarten DhaenensDieter Deforce

A1 Journal Article in STEM CELL RESEARCH

In vitro human embryonic stem cell hematopoiesis mimics MYB independent yolk sac hematopoiesis

Stijn VanheeKatrien De MulderYasmine Van CaeneghemNadine Van RoyBjörn MentenImke VelgheJan PhilippéTom TaghonGeorges LeclercqTessa Kerre et al.

Integrative analysis of the NOTCH1 regulatory network identifies key downstream lncRNAs in acute T-cell lymphoblastic leukemia and normal T-cell development

Annelynn WallaertKaat DurinckPieter RondouInge Van de WalleWouter Van LoockePieter-Jan VoldersMaté OngenaertNadine Van RoyBruce PoppeYves Benoit et al.

Juvenile myelomonocytic leukaemia: the quest for more specific therapies

Hetty HelsmoortelTim LammensNadine Van RoyJan PhilippéPascale De PaepeYves BenoitFranki SpelemanPieter Van VlierbergheBarbara De Moerloose

A2 Journal Article in BELGIAN JOURNAL OF HEMATOLOGY

MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia

Evelien MetsGert Van PeerJoni Van der MeulenMichael BoiceTom TaghonSteven GoossensPieter MestdaghYves BenoitBarbara De MoerlooseNadine Van Roy et al.

A1 Journal Article in HAEMATOLOGICA

Prognostic relevance of CD200/BTLA deletions in pediatric precursor-B cell acute lymphoblastic leukemia treated according to the EORTD-CLG 58951 protocol

Farzaneh GhazaviTim LammensEmmanuelle ClappierStefan SuciuAurélie CayeSamira ZegrariMarleen BakkusNathalie GrardelYves BenoitYves Bertrand et al.

Study of genomic alterations in colon carcinoma by array comparative genomic hybridization

Evi MampaeyAnnelies FieuwThalia Van LaethemNadine Van RoyLiesbeth FerdinandeWim CeelenPiet PattynYves Van NieuwenhoveKim De RuyckKaren Geboes et al.

The NOTCH1 driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia

Annelynn WallaertKaat DurinckPieter RondouInge Van de WalleWouter VanloockePieter-Jan VoldersSuzanne VanhauwaertEllen GeerdensMaté OngenaertNadine Van Roy et al.

The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia

Kaat DurinckAnnelynn WallaertInge Van de WalleWouter Van LoockePieter-Jan VoldersSuzanne VanhauwaertEllen GeerdensYves BenoitNadine Van RoyBruce Poppe et al.

A1 Journal Article in HAEMATOLOGICA

The epigenetic landscape of T-cell acute lymphoblastic leukemia

Joni Van der MeulenNadine Van RoyPieter Van VlierbergheFranki Speleman

A1 Journal Article in INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Treatment of human embryos with the TGFβ inhibitor SB431542 increases epiblast proliferation and permits successful human embryonic stem cell derivation

Margot Van der JeughtBjörn HeindryckxThomas O'LearyGalbha DuggalSabitri GhimireSylvie LiermanNadine Van RoySusana Marina Chuva de Sousa LopesTom DerooDieter Deforce et al.

A1 Journal Article in HUMAN REPRODUCTION

2013

CLL cells respond to B-cell receptor stimulation with a microRNA/mRNA signature associated with MYC activation and cell cycle progression

Valerie PedeAns RomboutJolien VermeireEvelien NaessensPieter MestdaghNore RobberechtHanne VanderstraetenNadine Van RoyJo VandesompeleFranki Speleman et al.

A1 Journal Article in PLOS ONE

CMYB expression during human in vitro hematopoiesis

Stijn VanheeYasmine Van CaeneghemKatrien De MulderImke VelgheSylvie TaveirneNadine Van RoyBjörn MentenSylvia SnauwaertGreet VerstichelMelissa Dullaers et al.

Characterisation of genome-wide copy number aberrations in colon cancer

Evi MampaeyNadine Van RoyKim De RuyckLiesbeth FerdinandeWim CeelenYves Van NieuwenhovePiet PattynKaren GeboesStéphanie Laurent

Expanding the TLX1 regulate in T-cell acute lymphoblastic leukemia towards long non-coding RNAs

Kaat DurinckJoni Van der MeulenMaté OngenaertPieter-Jan VoldersAnnelynn WallaertNadine Van RoyYves BenoitBruce PoppePieter MestdaghJo Vandesompele et al.

Expanding the TLX1-regulome in T cell acute lymphoblastic leukemia towards long non-coding RNAs

Kaat DurinckJoni Van der MeulenMaté OngenaertPieter-Jan VoldersAnnelynn WallaertNadine Van RoyYves BenoitBruce PoppePieter MestdaghJo Vandesompele et al.

Focal DNA copy number changes in neuroblastoma target MYCN regulated genes

Candy KumpsAnnelies FieuwPieter MestdaghBjörn MentenSteve LefeverFilip PattynSara De BrouwerTom SanteJohannes Hubertus SchulteAlexander Schramm et al.

A1 Journal Article in PLOS ONE

The need for transparency and good practices in the qPCR literature

Stephen A BustinVladimir BenesJeremy GarsonJan HellemansJim HuggettMikael KubistaReinhold MuellerTania NolanMichael W PfafflGregory Shipley et al.

A1 Journal Article in NATURE METHODS

miRNAs distinguish children with myelodysplastic syndrome from healthy donors

Hetty HelsmoortelTim LammensPieter MestdaghNadine Van RoyAnne UyttebroeckAlina FersterYves BenoitJo VandesompeleFranki SpelemanPieter Van Vlierberghe et al.

miRNAs distinguish children with myelodysplastic syndrome from healthy donors

Hetty HelsmoortelTim LammensPieter MestdaghNadine Van RoyAnne UyttebroeckAlina FersterYves BenoitJo VandesompeleFranki SpelemanPieter Van Vlierberghe et al.

2012

Demonstration of microchimerism in pregnant sows and effects of congenital PRRSV infection

Uladzimir KarniychukWander Van BreedamNadine Van RoyClaire Rogel-GaillardHans Nauwynck

A1 Journal Article in VETERINARY RESEARCH

Demonstration of microchimerism in pregnant sows and fetuses and putative microchimerism involvement in the pathogenesis of congenital PRRSV infection

Uladzimir KarniychukWander Van BreedamNadine Van RoyC Rogel-GaillardHans Nauwynck

High-risk clonal evolution in chronic B-lymphocytic leukemia: single-center interphase fluorescence in situ hybridization study and review of the literature

Ann JanssensNadine Van RoyBruce PoppeLucien NoensJan PhilippéFranki SpelemanFritz Offner

A1 Journal Article in EUROPEAN JOURNAL OF HAEMATOLOGY

Identification of a novel recurrent 1q42.2-1qter deletion in high risk MYCN single copy 11q deleted neuroblastomas

Annelies FieuwCandy KumpsAlexander SchrammFilip PattynBjörn MentenFrancesca AntonacciPeter SudmantJohannes H SchulteNadine Van RoySarah Vergult et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Isolation of disseminated neuroblastoma cells from bone marrow aspirates for pretreatment risk assessment by array comparative genomic hybridization

Mado VandewoestyneCandy KumpsKatrien SwertsBjörn MentenTim LammensJan PhilippéKatleen De PreterGenevieve LaureysNadine Van RoyFranki Speleman et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

N-Cadherin in neuroblastoma disease : expression and clinical significance

Tim LammensKatrien SwertsLara DeryckeANNEMIE DE CRAEMERSara De BrouwerKatleen De PreterNadine Van RoyJo VandesompeleFranki SpelemanJan Philippé et al.

A1 Journal Article in PLOS ONE

Study of the miRNome of childhood myelodysplastic syndrome

Hetty HelsmoortelTim LammensNadine Van RoyAnne UyttebroeckAlina FersterYves BenoitFranki SpelemanBarbara De Moerloose

2011

A multilocus technique for risk evaluation of patients with neuroblastoma

Inge M AmbrosBettina BrunnerGerhard AignerClare BedwellKlaus BeiskeJean BénardNick BownValerie CombaretJerome CouturierRaffaella Defferrari et al.

A1 Journal Article in CLINICAL CANCER RESEARCH

EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells

An De WeerJoni Van der MeulenPieter RondouTom TaghonTorsten A KonradKatleen De PreterPieter MestdaghTom Van MaerkenNadine Van RoyMarta Jeison et al.

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Fetal and maternal cells are not present in the porcine myometrium and fetal placentas, respectively, at the last stage of gestation

Uladzimir KarniychukWander Van BreedamClaire Rogel-GaillardNadine Van RoyHans Nauwynck

Identification of a new rare recurrent 1q42.2-qter deletion in neuroblastoma

Annelies FieuwCandy KumpsAlexander SchrammBjörn MentenJohannes SchulteNadine Van RoySarah VergultRosa NogueraRogier VersteegR Stallings et al.

Refinement of 1p36 alterations not involving PRDM16 in myeloid and lymphoid malignancies

François P DuhouxGeneviève AmeyeVirginie LambotChristian HerensFrédéric LambertSophie RaynaudIwona WlodarskaLucienne MichauxCatherine Roche-LestienneElise Labis et al.

A1 Journal Article in PLOS ONE

Regulatory networks governed by microRNAs in T-ALL oncogenesis and normal T-cell development

Joni Van der MeulenEvelien MetsPieter MestdaghPeter PipelersTom TaghonDavid Camacho TrujilloDavid AvranGert Van PeerNadine Van RoyOlivier Thas et al.

Sibling and fetal microchimerism in healthy and porcine reproductive and respiratory syndrome virus infected dams

Uladzimir KarniychukWander Van BreedamClaire Rogel-GaillardNadine Van RoyHans Nauwynck

miRNA Expression profiling enables risk stratification in archived and fresh neuroblastoma tumor samples

Katleen De PreterPieter MestdaghJoëlle VermeulenFjoralba ZekaAlene NaranjoIsabella BrayVictoria CastelCaifu ChenElzbieta DrozynskaAngelika Eggert et al.

A1 Journal Article in CLINICAL CANCER RESEARCH

2010

Epidermal growth factor receptor and K-RAS status in two cohorts of squamous cell carcinomas

Nancy Van DammePhilippe DeronNadine Van RoyPieter DemetterAlain BolsJo Van DorpeFilip BaertJean-Luc Van LaethemFranki SpelemanPatrick Pauwels et al.

A1 Journal Article in BMC CANCER

Identification of two critically deleted regions within chromosome segment 7q35-q36 in EVI1 deregulated myeloid leukemia cell lines

An De WeerBruce PoppeSarah VergultPieter Van VlierbergheMarjan PetrickRobrecht De BockYves BenoitLucien NoensAnne De PaepeNadine Van Roy et al.

A1 Journal Article in PLOS ONE

MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors

Pieter MestdaghE FredlundFilip PattynJH SchulteD MuthJoëlle VermeulenCandy KumpsS SchlierfKatleen De PreterNadine Van Roy et al.

A1 Journal Article in ONCOGENE

Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification

Sara De BrouwerKatleen De PreterCandy KumpsPiotr ZabrockiMichael PorcuEllen M WesterhoutArjan LakemanJo VandesompeleJasmien HoebeeckTom Van Maerken et al.

A1 Journal Article in CLINICAL CANCER RESEARCH

Multiplex Amplicon Quantification (MAQ), a fast and efficient method for the simultaneous detection of copy number alterations in neuroblastoma

Candy KumpsNadine Van RoyL HeyrmanD GoossensJ Del-FaveroR NogueraJo VandesompeleFranki SpelemanKatleen De Preter

A1 Journal Article in BMC GENOMICS

PHF6 mutations in T-cell acute lymphoblastic leukemia

Pieter Van VlierbergheTeresa PalomeroHossein KhiabanianJoni Van der MeulenMireia CastilloNadine Van RoyBarbara De MoerlooseJan PhilippéSara Gonzalez-GarciaMaria L Toribio et al.

A1 Journal Article in NATURE GENETICS

Signaling of ERBB receptor tyrosine kinases promotes neuroblastoma growth in vitro and in vivo

Kristen N RichardsPatrick A Zweidler-McKayNadine Van RoyFranki SpelemanJesus TrevinoPeter E ZageDennis PM Hughes

A1 Journal Article in CANCER

2009

Chromosome 3p microsatellite allelotyping in neuroblastoma: a report on the technical hurdles

Jasmien HoebeeckBram De WildeEvi MichelsValerie CombaretNurten YigitEls De SmetNadine Van RoyEric StanbridgeNing RuGenevieve Laureys et al.

A1 Journal Article in CANCER INVESTIGATION

Comparison of miRNA profiles of microdissected Hodgkin/Reed-Sternberg cells and Hodgkin cell lines versus CD77+ B-cells reveals a distinct subset of differentially expressed miRNAs

Pieter Van VlierbergheAn De WeerPieter MestdaghTom FeysKatleen De PreterAnne De PaepeKathleen LambeinJo VandesompeleNadine Van RoyBruno Verhasselt et al.

A1 Journal Article in BRITISH JOURNAL OF HAEMATOLOGY

Detection of Staphylococcus aureus in nasal tissue with peptide nucleic acid-fluorescence in situ hybridization

Marie-Noelle CorriveauNan ZhangGabriële HoltappelsNadine Van RoyClaus Bachert

A1 Journal Article in AMERICAN JOURNAL OF RHINOLOGY & ALLERGY

Downregulation of miR-449a is essential for the survival of EVI1 positive leukemic cells through modulation of NOTCH1 and BCL2

An De WeerPieter MestdaghKatleen De PreterJoni Van der MeulenPieter Van VlierbergheTom Van MaerkenNadine Van RoyMarta JeisonIsaac YanivBarbara Cauwelier et al.

Gebruik van genexpresieanalyse in de aanpak van neuroblastoom bij kinderen

Joëlle VermeulenKatleen De PreterPieter MestdaghFilip PattynAnne De PaepeNadine Van RoyGenevieve LaureysFranki SpelemanJo Vandesompele

A4 Journal Article in ONCO (NEDERLANDSE ED.)

Improved Detection of Chromosomal Abnormalities in Chronic Lymphocytic Leukemia by Conventional Cytogenetics Using CpG Oligonucleotide and Interleukin-2 Stimulation: A Belgian Multicentric Study

N PutP KoningsK RackM JamarNadine Van RoyJM LiboutonP VannuffelD SartenaerG AmeyeFranki Speleman et al.

A1 Journal Article in GENES CHROMOSOMES & CANCER

Is the risk of developing AML or MDS increased in X-linked neutropenia

K BeelM CotterJ BlatnyC ChatelainA UyttebroeckBarbara De MoerlooseNadine Van RoyG. VerhoefH DemuynckP Vandenberghe

MICRORNA SIGNATURES IN GENETIC SUBTYPES OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA

Joni Van der MeulenPieter Van VlierberghePieter MestdaghJo VandesompeleBruce PoppeNadine Van RoyTom TaghonJean PlumB. CauwelierDLD Selleslag et al.

MODULATION OF MIR-449A EXPRESSION DECREASES CELL VIABILITY, INCREASES APOPTOSIS AND INDUCES DIFFERENTIATION IN EVI1 DEREGULATED LEUKEMIA CELLS

An De WeerBruce PoppePieter MestdaghKatleen De PreterPieter Van VlierbergheNadine Van RoyM JeisonB CauwelierBruno VerhasseltJan Philippé et al.

Predicting outcomes for children with neuroblastoma using a multigene-expression signature: a retrospective SIOPEN/COG/GPOH study

Joëlle VermeulenKatleen De PreterArlene NaranjoLiesbeth VercruysseNadine Van RoyJan HellemansKatrien SwertsSophie BravoPaolo ScaruffiGian Paolo Tonini et al.

A1 Journal Article in LANCET ONCOLOGY

The emerging molecular pathogenesis of neuroblastoma : implications for improved risk assessment and targeted therapy

Nadine Van RoyKatleen De PreterJasmien HoebeeckTom Van MaerkenFilip PattynPieter MestdaghJoëlle VermeulenJo VandesompeleFranki Speleman

A1 Journal Article in GENOME MEDICINE

2008

A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the human NBPF1 and ACCN1 genes

Karl VandepoeleVanessa AndriesNadine Van RoyKatrien StaesJo VandesompeleGenevieve LaureysEls De SmetGeert BerxFranki SpelemanFrans Van Roy

A1 Journal Article in PLOS ONE

A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the the human NBPF1 and ACCN1 genes

Frans Van RoyKlaas VandepoeleNadine Van RoyVanessa AndriesKatrien StaesJo VandesompeleGenevieve LaureysEls De SmetGeert BerxFranki Speleman

EGFR and K-RAS gene status evaluation in anal canal squamous cell carcinoma

N Van DammeNadine Van RoyFranki SpelemanA BolsJo Van DorpeP PauwelsM Peeters

EVI1 overexpression in t(3;17) positive myeloid malignancies results from juxtaposition of EVI1 to the MSI2 locus at 17q22

An De WeerFranki SpelemanBarbara CauwelierNadine Van RoyNurten YigitBruno VerhasseltBarbara De MoerlooseYves BenoitLucien NoensDominik Selleslag et al.

A1 Journal Article in HAEMATOLOGICA-THE HEMATOLOGY JOURNAL

EVII activation in blast crisis CML due to juxtaposition to the rare 17q22 partner region as part of a 4-way variant translocation t(9;22)

An De WeerBruce PoppeBarbara CauwelierA CARLIERJ DIERICKBruno VerhasseltJan PhilippéNadine Van RoyFranki Speleman

A1 Journal Article in BMC CANCER

Evaluation of EGFR and K-RAS gene status in squamous cell carcinoma of the anal canal.

Nancy Van DammeNadine Van RoyFranki SpelemanA BOLSJ VAN DORPEPatrick PauwelsMarc Peeters

Identification of 2 putative critical segments of 17q gain in neuroblastoma through integrative genomics

Jo VandesompeleEvi MichelsKatleen De PreterBjörn MentenAlexander SchrammAngelika EggertPeter F AmbrosValérie CombaretNadine FrancotteFrancesca Antonacci et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Investigation of the EGFR and K-RAS gene status in squamous cell carcinoma of the anal canal

Nancy Van DammeNadine Van RoyPieter DemetterFranki SpelemanA BolsJo Van DorpeN NagyJ Van LaethemPatrick PauwelsMarc Peeters

Low-cost dedicated mini-arrays for high-throughput analysis of DNA copy-number alterations in neuroblastoma

Katleen De PreterBjörn MentenSara De BrouwerCandy KumpsEvi MichelsNadine Van RoyJo VandesompeleFranki Speleman

A1 Journal Article in CANCER LETTERS

MICRORNA PROFILING OF EVI1 DEREGULATED MYELOID LEUKEMIA

An De WeerBruce PoppePieter MestdaghPieter Van VlierbergheNadine Van RoyAnne De PaepeBruno VerhasseltJo VandesompeleFranki Speleman

MicroRNA signatures in genetic subtypes of T-cell acute lymphoblastic leukemia.

Pieter Van VlierbergheBruce PoppeNadine Van RoyTom TaghonJean PlumB CauwelierD SelleslagP HeimannP VandenbergheN Dastugue et al.

2007

A detailed inventory of DNA copy number alterations in four commonly used Hodgkin lymphoma cell lines

Tom FeysBruce PoppeKatleen De PreterNadine Van RoyBruno VerhasseltPascale De PaepeAnne De PaepeFranki Speleman

A detailed inventory of DNA copy number alterations in four commonly used Hodgkin's lymphoma cell lines

Tom FeysBruce PoppeKatleen De PreterNadine Van RoyBruno VerhasseltPascale De PaepeAnne De PaepeFranki Speleman

A1 Journal Article in HAEMATOLOGICA

Array CGH analysis of subnanogram quantities of DNA using whole genome amplification: opportunities for detection of copy number alterations in Hodgkin's lymphoma

Tom FeysBart PoppeBruno VerhasseltPascale De PaepeBjörn MentenJo VandesompeleNadine Van RoyAnne De PaepeFranki Speleman

ArrayCGH based classification of neuroblastoma into genomic subgroups

Sara De BrouwerEvi MichelsJo VandesompeleKatleen De PreterJasmien HoebeeckJoëlle VermeulenAlexander SchrammJan J MolenaarBjörn MentenBarbara Marques et al.

ArrayCGH-based classification of neuroblastoma into genomic subgroups

Evi MichelsJo VandesompeleKatleen De PreterJasmien HoebeeckJoëlle VermeulenAlexander SchrammJan J MolenaarBjörn MentenBarbara MarquesRaymond L Stallings et al.

A1 Journal Article in GENES CHROMOSOMES & CANCER

Clinical, cytogenetic and molecular characteristics of 14 T-ALL patients carrying the TCR β-HOXA rearrangement : a study of the Groupe Francophone de Cytogénétique Hématologique

Barbara CauwelierH CavéC GervaisM LessardC BarinC PerotJ Van den AkkerF MugneretC CharrinMP Pagès et al.

A1 Journal Article in LEUKEMIA

DRAQ5: improved flow cytometric residual disease detection DNA content analysis and minimal in childhood malignancies

Katrien SwertsNadine Van RoyYves BenoitGenevieve LaureysJan Philippé

A1 Journal Article in CLINICA CHIMICA ACTA

De bijdrage van M-FISH aan de moleculaire diagnostiek in de hemato-oncologie

Bruce PoppeNadine Van RoyNurten YigitAnne De PaepeFranki Speleman

A2 Journal Article in Ned Tijdschr Hematol

Detection of DNA copy number alterations in cancer by array comparative genomic hybridization

Evi MichelsKatleen De PreterNadine Van RoyFranki Speleman

A1 Journal Article in GENETICS IN MEDICINE

High resolution tiling-path BAC array deletion mapping suggests commonly involved 3p21-p22 tumor suppressor genes in neuroblastoma and more frequent tumors

Jasmien HoebeeckEvi MichelsBjörn MentenNadine Van RoyAngelika EggertAlexander SchrammKatleen De PreterNurten YigitEls De SmetAnne De Paepe et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Identification of EVI1 transcriptional target genes using RNAI

An De WeerBruce PoppeB CAUWEUERNadine Van RoyBruno VerhasseltFranki Speleman

Integrative genomics in neuroblastoma research

Franki SpelemanKatleen De PreterEvi MichelsJasmien HoebeeckFilip PattynJoëlle VermeulenNadine Van RoyAnne De PaepeGenevieve LaureysJo Vandesompele

MicroRNA profiling of EVI1 deregulated myeloid leukemia

An De WeerBruce PoppePieter MestdaghNadine Van RoyAnne De PaepeBruno VerhasseltJo VandesompeleFranki Speleman

New insights into the genetic basis of neuroblastoma

Franki SpelemanKatleen De PreterJasmien HoebeeckNadine Van RoyJo Vandesompele

A4 Journal Article in VERHANDELINGEN VAN DE KONINKLIJKE ACADEMIE VOOR GENEESKUNDE VAN BELGIË

2006

EBV negative Richter's syndrome from a coexistent clone after salvage treatment with alemtuzumab in a CLL patient

A JANSSENSM BERTHP DE PAEPEBruno VerhasseltNadine Van RoyLucien NoensJan PhilippéFritz Offner

A1 Journal Article in AMERICAN JOURNAL OF HEMATOLOGY

Genome wide measurement of DNA copy number changes in neuroblastoma: dissecting amplicons and mapping losses, gains and breakpoints

Evi MichelsJo VandesompeleJasmien HoebeeckBjörn MentenKatleen De PreterGenevieve LaureysNadine Van RoyFranki Speleman

A1 Journal Article in CYTOGENETIC AND GENOME RESEARCH

MYC-containing double minutes in hematologic malignancies: evidence in favor of the episome model and exclusion of MYC as the target gene

CT STORLAZZIT FIORETOSC SURACEA LONOCEA MASTRORILLIB STROMBECKP D'ADDABBOF IACOVELLIC MINERVINIA AVENTIN et al.

A1 Journal Article in HUMAN MOLECULAR GENETICS

Recurrent T(3;17)translocations in AML with EVI1 rearrangement

An De WeerBruce PoppeB CauwelierNadine Van RoyN DASTUGUEBarbara De MoerlooseYves BenoitLucien NoensAnne De PaepeFranki Speleman

Recurrent t(3;17) translocations in AML with EVII rearrangement.

A De WeerBruce PoppeB CauwelierNadine Van RoyN DastugueBarbara De MoerlooseYves BenoitLucien NoensAnne De PaepeFranki Speleman

Screening for EVII: ectopic expression absent in T-cell acute lymphoblastic leukemia patients and cell lines

An De WeerBruce PoppeB CauwelierNadine Van RoyN DASTUGUEA HAGEMEIJERAnne De PaepeFranki Speleman

A1 Journal Article in CANCER GENETICS AND CYTOGENETICS

The TCRB-HOXA rearrangement in T-ALL leads to a specific increase of the alternative HOXA10b transcript

B CauwelierH CAVÉN DASTUGUEP HEIMANNH ANTOINE-POIRELBruno VerhasseltYves BenoitBarbara De MoerlooseNadine Van RoyA HAGEMEIJER et al.

The von Hippel-Lindau tumor suppressor gene expression level has prognostic value in neuroblastoma

Jasmien HoebeeckJo VandesompeleHelén NissonKatleen De PreterNadine Van RoyEls De SmetNurten YigitAnne De PaepeGenevieve LaureysSven Påhlman et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Translocation-excision-deletion-amplification mechanism leading to nonsyntenic coamplification of MYC and ATBF1

Nadine Van RoyJo VandesompeleBjörn MentenH NILSSONEls De SmetM ROCCHIAnne De PaepeS PAHLMANFranki Speleman

A1 Journal Article in GENES CHROMOSOMES & CANCER

2005

A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias

Franki SpelemanBarbara CauwelierN DASTUGUEJ COOLSBruno VerhasseltBruce PoppeNadine Van RoyJo VandesompeleC GRAUXA UYTTEBROECK et al.

A1 Journal Article in LEUKEMIA

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution

Karl VandepoeleNadine Van RoyKatrien StaesFranki SpelemanFrans Van Roy

A1 Journal Article in MOLECULAR BIOLOGY AND EVOLUTION

No evidence for correlation of DDX1 gene amplification with improved survival probability in patients with MYCN-amplified neuroblastomas

Katleen De PreterFranki SpelemanValérie CombaretJohn LunecJulien BoardAndy PearsonAnne De PaepeNadine Van RoyGenevieve LaureysJo Vandesompele

A1 Journal Article in JOURNAL OF CLINICAL ONCOLOGY

Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11

Katleen De PreterJo VandesompeleBjörn MentenPhilippa CarrHeike FieglerAnders EdsjöNigel P CarterNurten YigitWim WaelputNadine Van Roy et al.

A1 Journal Article in BMC GENOMICS

Unequivocal delineation of clinicogenetic subgroups and development of a new model for improved outcome prediction in neuroblastoma

Jo VandesompeleM BAUDISKatleen De PreterNadine Van RoyP AMBROSN BOWNC BRINKSCHMIDTH CHRISTIANSENV COMBARETM LASTOWSKA et al.

A1 Journal Article in JOURNAL OF CLINICAL ONCOLOGY

2004

Claes Lundsteen - in memoriam

J GRAHAME BLENNOWMG BOAVIDAN CARTERC CREMERT CREMERO DELATTRET GERDESE GRANUMA HAGEMEIJER et al.

Gene-expression profiling reveals distinct expression patterns for classic versus variant Merkel cell phenotypes and new classifier genes to distinguish Merkel cell from small-cell lung carcinoma

M VAN GELEGM BOYLEAL COOKJo VandesompeleTom BoonefaesPieter RottiersNadine Van RoyAnne De PaepePG PARSONSJH LEONARD et al.

A1 Journal Article in ONCOGENE

Loss-of-function mutations in LEMD3 result in osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis

Jan HellemansO PREOBRAZHENSKAAndy WillaertP DEBEERPETER VERDONKT COSTAK JANSSENSBjörn MentenNadine Van RoyStefan Vermeulen et al.

A1 Journal Article in NATURE GENETICS

Molecular analysis of the putative tumour-suppressor gene EXTL1 in neuroblastoma patients and cell lines

D MATHYSENNadine Van RoyW VAN HULGenevieve LaureysP AMBROSFranki SpelemanW WUYTS

A1 Journal Article in EUROPEAN JOURNAL OF CANCER

Molecular cytogenetic analysis of complex chromosomal rearrangements in patients with mental retardation and congenital malformations: delineation of 7q21.11 breakpoints

Stefan VermeulenBjörn MentenNadine Van RoyHeidi Van LimbergenAnne De PaepeGeert MortierFranki Speleman

A1 Journal Article in AMERICAN JOURNAL OF MEDICAL GENETICS PART A

No evidence for involvement of SDHD in neuroblastoma pathogenesis

Katleen De PreterJo VandesompeleJasmien HoebeeckCaroline VandenbroeckeJoél SmetAnnick NuytsGenevieve LaureysValérie CombaretNadine Van RoyFrank Roels et al.

A1 Journal Article in BMC CANCER

ZFHX3 (zinc finger homeobox 3)

Nadine Van RoyFranki Speleman

A2 Journal Article in ATLAS OF GENETICS AND CYTOGENETICS IN ONCOLOGY AND HAEMATOLOGY

2003

Application of laser capture microdissection in genetic analysis of neuroblastoma and neuroblastoma precursor cells

Katleen De PreterJo VandesompelePierre HeimannMark M KockxMireille Van GeleJasmien HoebeeckEls De SmetMartine DemarcheGenevieve LaureysNadine Van Roy et al.

A1 Journal Article in CANCER LETTERS

Evidence for involvement of a tumor suppressor gene on 1p in malignant peripheral nerve sheath tumors

Nadine Van RoyM VAN GELEJo VandesompeleLudwine MessiaenSimon Van BelleR SCIOTK MORTELEJ GYSELINCKE MICHIELSRamses Forsyth et al.

A1 Journal Article in CANCER GENETICS AND CYTOGENETICS

Gene expression profiling reveals two distinct subtypes of Merkel cell carcinoma

M VAN GELEG BOYLEAL COOKTom BoonefaesPieter RottiersNadine Van RoyAnne De PaepeP PARSONSJH LEONARDFranki Speleman

Gene expression profiling reveals two distinct subtypes of Merkel cell carcinoma. The Merkel cell

M VAN GELEG BOYLEA COOKTom BoonefaesP ROTTIERSNadine Van RoyAnne De PaepeP PARSONSJ LEONARDFranki Speleman

Quality assessment of genetic markers used for therapy stratification

IM AMBROSJ BENARDM BOAVIDAN BOWNH CARONV COMBARETJ COUTURIERC DARNFORSO DELATTREJ FREEMAN-EDWARD et al.

A1 Journal Article in JOURNAL OF CLINICAL ONCOLOGY

2002

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Jo VandesompeleKatleen De PreterFilip PattynBruce PoppeNadine Van RoyAnne De PaepeFranki Speleman

A1 Journal Article in GENOME BIOLOGY

Combined karyotyping, CGH and M-fish analysis allows detailed characterization of unidentified chromosomal rearrangements in Merkel cell carcinoma.

Mireille Van GeleJH LEONARDNadine Van RoyHeidi Van LimbergenSimon Van BelleVeronique CocquytH SALWENAnne De PaepeFranki Speleman

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type I patients.

Nadine Van RoyJo VandesompeleGeert BerxK STAESMireille Van GeleEls De SmetAnne De PaepeGenevieve LaureysP VAN DER DRIFTR VERSTEEG et al.

A1 Journal Article in GENES CHROMOSOMES & CANCER

Meerkleuren fluorescentie in situ hybridisatie: methodologie en toepassingen in diagnostiek en onderzoek

Heidi Van LimbergenBruce PoppeStefan VermeulenNadine Van RoyAnne De PaepeFranki Speleman

A4 Journal Article in TIJDSCHRIFT VAN DE BELGISCHE VERENIGING VAN LABORATORIUM-TECHNOLOGEN = REVUE DE L'ASSOCIATION BELGE DES TECHNOLOGUES DE LABORATOIRE

Quantification of MYCN, DDX1, and NAG gene copy number in neuroblastoma using a real-time quantitative PCR assay.

Katleen De PreterFranki SpelemanV COMBARETJ LUNECGenevieve LaureysB EUSSENN FRANCOTTEJ BOARDA PEARSONAnne De Paepe et al.

A1 Journal Article in MODERN PATHOLOGY

2001

Chromosomal aberrations in Bloom syndrome patients with myeloid malignancies.

Bruce PoppeHeidi Van LimbergenNadine Van RoyE VANDECRUYSAnne De PaepeYves BenoitFranki Speleman

A1 Journal Article in CANCER GENETICS AND CYTOGENETICS

Combined M-FISH and CGH analysis allows comprehensive description of genetic alterations in neuroblastoma cell lines.

Nadine Van RoyHeidi Van LimbergenJo VandesompeleMireille Van GeleBruce PoppeH SALWENGenevieve LaureysN MANOELAnne De PaepeFranki Speleman

A1 Journal Article in GENES CHROMOSOMES & CANCER

Comparative genomic hybridization (CGH) analysis of stage 4 neuroblastoma reveals high frequency of 11Q deletion in tumors lacking MYCN amplification.

D PLANTAZJo VandesompeleNadine Van RoyM LASTOWSKAN BOWNV COMBARETMC FAVROTO DELATTREJ MICHONJ BENARD et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Deletion of chromosome 11q is the most frequent deletion detected by CGH in metastatic neuroblastoma lacking MYCN amplification

D PLANTAZJ VANDESOMPELENadine Van RoyN BROWNJ NICHOLSONM LASTOWSKAA PEARSONC BRINKSCHMIDTH CHRISTIANSENF LAMPERT et al.

A2 Journal Article in Int. J. of Cancer

Frequent allelic loss at 10q23 but low incidence of PTEN mutations in Merkel cell carcinoma

Mireille Van GeleJ Helen LeonardNadine Van RoyAnthony L CookAnne De PaepeFranki Speleman

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Molecular cytogenetic and clinical findings in ETV6/ABL1-positive leukemia.

Heidi Van LimbergenHB BEVERLOOE VAN DRUNENAnn JanssensK HAHLENBruce PoppeNadine Van RoyP MARYNENAnne De PaepeR SLATER et al.

A1 Journal Article in GENES CHROMOSOMES & CANCER

Molecular cytogenetic definition of 17q translocation breakpoints in neuroblastoma.

M LASTOWSKANadine Van RoyN BOWNFranki SpelemanP ROBERTSJ LUNECT STRACHANADJ PEARSONMS JACKSON

A1 Journal Article in MEDICAL AND PEDIATRIC ONCOLOGY

Multicentre analysis of patterns of DNA gains and losses in 204 neuroblastoma tumors: How many genetic subgroups are there?

Jo VandesompeleFranki SpelemanNadine Van RoyGenevieve LaureysC BRINKSCHMIDTH CHRISTIANSENF LAMPERTM LASTOWSKAN BOWNA PEARSON et al.

A1 Journal Article in MEDICAL AND PEDIATRIC ONCOLOGY

2000

Chromosome 2 short arm translocations revealed by M-FISH analysis of neuroblastoma cell lines.

Nadine Van RoyHeidi Van LimbergenJo VandesompeleMireille Van GeleBruce PoppeGenevieve LaureysAnne De PaepeFranki Speleman

A1 Journal Article in MEDICAL AND PEDIATRIC ONCOLOGY

Deletion mapping on the short arm of chromosome 1 in Merkel cell carcinoma.

JH LEONARDAL COOKD NANCARROWN HAYWARDM VAN GELENadine Van RoyFranki Speleman

A1 Journal Article in CANCER DETECTION AND PREVENTION

Exhaustive mutation analysis of the NF1 gene allows identification of 95% of mutations and reveals a high frequency of unusual splicing defects.

Ludwine MessiaenT CALLENSGeert MortierDiane BeysenIna VandenbrouckeNadine Van RoyFranki SpelemanAnne De Paepe

A1 Journal Article in HUMAN MUTATION

Mutation analysis of P73 and TP53 in Merkel cell carcinoma.

Mireille Van GeleM KAGHADJH LEONARDNadine Van RoyJean NaeyaertMarie GeertsSimon Van BelleVeronique CocquytJ BRIDGER SCIOT et al.

A1 Journal Article in BRITISH JOURNAL OF CANCER

Structure and mutation analysis of the gene encoding DNA fragmentation factor 40 (caspase-activated nuclease), a candidate neuroblastoma tumour suppressor gene.

H JUDSONNadine Van RoyL STRAINJo VandesompeleMireille Van GeleFranki SpelemanDT BONTHRON

A1 Journal Article in HUMAN GENETICS

Subtelomeric familial translocation t(2;7)(q37;q35) leading to partial trisomy 7q35 -> qter: Molecular cytogenetic analysis and clinical phenotype in two generations.

Franki SpelemanB CALLENSKarl LoggheNadine Van RoyA JAUCHMR VERSCHRAEGEN-SPAEJG LEROY

A1 Journal Article in AMERICAN JOURNAL OF MEDICAL GENETICS

1999

Chromosome 7 short arm deletions and disease progression in CML

Bruce PoppeH VAN LIMBERGENANN JANSSENSNadine Van RoyBarbara De MoerlooseJ PHILLIPEAnne De PaepeFritz OffnerFranki Speleman

Closing in an the BPES gene on 3q23: Mapping of a de nova reciprocal translocation t(3;4)(q23;p15.2) breakpoint within a 45-kb cosmid and mapping of three candidate genes, RBP1, RBP2, and beta '-COP, distal to the breakpoint

Elfride De BaereNadine Van RoyFranki SpelemanY FUKUSHIMAAnne De PaepeLudwine Messiaen

A1 Journal Article in GENOMICS

Cytogenetic findings in bloom syndrome patients with myeloid malignancies

Bruce PoppeYves BenoitH VAN LIMBERGENNadine Van RoyEls VandecruysA JAUCHAnne De PaepeJ GERMANFranki Speleman

Identification of a novel CBFB/MYH11 fusion in a patient with AML-M1 and a t(16;16)(p13;q22)

H VAN LIMBERGENB VAN DER REIJDENBruce PoppeFritz OffnerNadine Van RoyH DAUWERSEAnne De PaepeFranki Speleman

Mapping of novel regions of DNA gain and loss by comparative genomic hybridization in esophageal carcinoma in the black and colored populations of South Africa.

L DU PLESSISE DIETZSCHMireille Van GeleNadine Van RoyP VAN HELDENMI PARKERDK MUGWANYAM DE GROOTMP MARXMJ KOTZE et al.

A1 Journal Article in CANCER RESEARCH

Neuroblastoma: from molecular cytogenetics to gene expression profiling

Jo VandesompeleNadine Van RoyGeert BerxD PLANTAZAnne De PaepeGenevieve LaureysFrans Van RoyFranki Speleman

Refined physical mapping and genomic structure of the EXTL1 gene.

W WUYTSN SPIEKERNadine Van RoyK DE BOULLEAnne De PaepePJ WILLEMSW VAN HULR VERSTEEGFranki Speleman

A1 Journal Article in CYTOGENETICS AND CELL GENETICS

Unusual chromosome 16 rearrangement with absence of classical CBFB/MYH11 fusion transcripts

H VAN LIMBERGENBA VAN DER REIJDENBruce PoppeNadine Van RoyH DAUWERSEAnne De PaepeFranki Speleman

1998

Assignment of SHOX2 (alias OG12X and SHOT) to human chromosome bands 3q25 -> q26.1 by in situ hybridization.

Elfride De BaereFranki SpelemanNadine Van RoyAnne De PaepeLudwine Messiaen

A1 Journal Article in CYTOGENETICS AND CELL GENETICS

Assignment of the cellular retinol-binding protein 1 gene (RBP1) and of the coatomer beta ' subunit gene (COPB2) to human chromosome band 3q23 by in situ hybridization

Elfride De BaereFranki SpelemanNadine Van RoyAnne De PaepeLudwine Messiaen

A1 Journal Article in CYTOGENETICS AND CELL GENETICS

Assignment of the cellular retinol-binding protein 2 gene (RBP2) to human chromosome band 3q23 by in situ hybridization

Elfride De BaereFranki SpelemanNadine Van RoyK MORTIERAnne De PaepeLudwine Messiaen

A1 Journal Article in CYTOGENETICS AND CELL GENETICS

Characteristic pattern of chromosomal gains and losses in Merkel cell carcinoma detected by comparative genomic hybridization

Mireille Van GeleFranki SpelemanJo VandesompeleNadine Van RoyJH Leonard

A1 Journal Article in CANCER RESEARCH

Cytogenetic and molecular analysis of cellular atypical mesoblastic nephroma.

Franki SpelemanE VAN DEN BERGCatharina DhoogeW OOSTERHUISB REDEKERChristian De PotterRYJ TAMMINGANadine Van RoyM MANNENS

A1 Journal Article in GENES CHROMOSOMES & CANCER

Extended sperm DNA fibres applied to high resolution physical gene mapping

T DineenFranki SpelemanNadine Van RoyA NolanJA Houghton

A2 Journal Article in ADVANCES IN REPRODUCTION

Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization.

Jo VandesompeleNadine Van RoyMireille Van GeleGenevieve LaureysP AMBROSP HEIMANNC DEVALCKE SCHUURINGP BROCKJ OTTEN et al.

A1 Journal Article in GENES CHROMOSOMES & CANCER

Identification of a third EXT-like gene (EXTL3) belonging to the EXT gene family.

W VAN HULW WUYTSJ HENDRICKXFranki SpelemanJ WAUTERSK DE BOULLENadine Van RoyP BOSSUYTPJ WILLEMS

A1 Journal Article in GENOMICS

Molecular analysis of lp36 breakpoints in two Merkel cell carcinomas.

Mireille Van GeleNadine Van RoySG RONANLudwine MessiaenJo VandesompeleMarie GeertsM NAEYAERTE BLENNOWI BAR-AMTK DAS GUPTA et al.

A1 Journal Article in GENES CHROMOSOMES & CANCER

Molecular cytogenetic delineation of 17q translocation breakpoints in neuroblastoma cell lines.

M LASTOWSKANadine Van RoyN BROWNFranki SpelemanJ LUNECT STRACHANADJ PEARSONMS JACKSON

A1 Journal Article in GENES CHROMOSOMES & CANCER

Molecular diagnostic evaluation of NF1 patients using the combined approach of karyotyping, fluorescent in situ hybridisation, the protein truncation assay and heteroduplex analysis

Ludwine MessiaenGeert MortierT CallensNadine Van RoyFranki SpelemanAnne De Paepe

Noonan-like phenotype in monozygotic twins with a duplication-deficiency of the long arm of chromosome 18 resulting from a maternal paracentric inversion.

W COURTENSD GROSSMANNadine Van RoyLudwine MessiaenE VAMOSV TOPPETD HAUMONTC STREYDIOA JAUCHJR VERMEESCH et al.

A1 Journal Article in HUMAN GENETICS

1997

A constitutional balanced 1;17 neuroblastoma translocation

P VAN DER DRIFTA CHANGenevieve LaureysNadine Van RoyA WESTERVELDFranki SpelemanR VERSTEEG

Absence of serum alanine aminotransferase activity in a neonate

Joris DelangheH VlaminckD BernardEddy RobberechtMarleen PraetM DeBuyzereJ QuatackerNadine Van RoyJV Duynslaegher

A1 Journal Article in CLINICAL CHEMISTRY

Absence of serum alanine aminotransferase activity in a neonate.

Joris DelangheH VLAMINCKD BERNARDEddy RobberechtMarleen PraetMarc De BuyzereJozef QuatackerNadine Van RoyJV DUYNSLAEGHER

A1 Journal Article in CLINICAL CHEMISTRY

Amplification units and translocation at chromosome 17q and c-erbB-2 overexpression in the pathogenesis of breast cancer.

Elisabeth CoeneVera SchelfhoutRA WINKLERAM SCHELFHOUTNadine Van RoyM GROOTECLAESFranki SpelemanCR DEPOTTER

A1 Journal Article in VIRCHOWS ARCHIV-AN INTERNATIONAL JOURNAL OF PATHOLOGY

Analysis of 1;17 translocation breakpoints in neuroblastoma: Implications for mapping of neuroblastoma genes.

Nadine Van RoyGenevieve LaureysMireille Van GeleG OPDENAKKERR MIURAP VAN DER DRIFTA CHANR VERSTEEGFranki Speleman

A1 Journal Article in EUROPEAN JOURNAL OF CANCER

Comparative genomic hybridization analysis of human neuroblastomas: Detection of distal 1p deletions and further molecular genetic characterization of neuroblastoma cell lines.

Nadine Van RoyA JAUCHM VANGELEGenevieve LaureysR VERSTEEGA DEPAEPET CREMERFranki Speleman

A1 Journal Article in CANCER GENETICS AND CYTOGENETICS

Expression of the MDR1 gene product P-glycoprotein in childhood neuroblastoma

Catharina DhoogeBarbara De MoerlooseYves BenoitNadine Van RoyJan PhilippéGenevieve Laureys

A1 Journal Article in CANCER

Identification and characterization of a novel member of the EXT gene family, EXTL2.

W WUYTSW VAN HULJ HENDRICKXFranki SpelemanJ WAUTERSK DE BOULLENadine Van RoyT VAN AGTMAELP BOSSUYTPJ WILLEMS

A1 Journal Article in EUROPEAN JOURNAL OF HUMAN GENETICS

Interstitial deletion 2q33.3-q34 in a boy with a phenotype resembling the Seckel syndrome.

W COURTENSFranki SpelemanLudwine MessiaenJ BORMANSNadine Van RoyE VAMOS

A1 Journal Article in AMERICAN JOURNAL OF MEDICAL GENETICS

Malignant melanoma of the soft parts (clear-cell sarcoma): Confirmation of EWS and ATF-1 gene fusion caused by a t(12;22) translocation.

Franki SpelemanO DELATTREM PETERE HAUBENNadine Van RoyE VANMARCK

A1 Journal Article in MODERN PATHOLOGY

Monosomy 22 in a mixed germ cell sex cord stromal tumor of the ovary

Franki SpelemanBart DermautChristian R De PotterMireille Van GeleNadine Van RoyAnne De PaepeGenevieve Laureys

A1 Journal Article in GENES CHROMOSOMES & CANCER

Sensitive and reliable detection of genomic imbalances in human neuroblastomas using comparative genomic hybridisation analysis.

Mireille Van GeleNadine Van RoyA JAUCHGenevieve LaureysYves BenoitVera SchelfhoutChristian De PotterP BROCKA UYTTEBROECKR SCIOT et al.

A1 Journal Article in EUROPEAN JOURNAL OF CANCER

1996

A putative tumor suppressor gene involved in Merkel cell carcinoma maps between p58 and D172

Franki SpelemanML GeertsFilomeen HaerynckBart DermautNadine Van Roy

Chromosomal region 1p35-36 encodes for several neuroblastoma suppressor loci

R VERSTEEGH CARONP VANDERDRIFTFranki SpelemanGenevieve LaureysNadine Van RoyNC CHENG

Localization by fluorescence in situ hybridization of the human functional beta-glucuronidase gene (GUSB) to 7q11.21->q11.22 and two pseudogenes to 5p13 and 5q13.

Franki SpelemanR VERVOORTNadine Van RoyI LIEBAERSWS SLYW LISSENS

A1 Journal Article in CYTOGENETICS AND CELL GENETICS

Molecular cytogenetic analysis of neuroblastoma

Nadine Van RoyAnne De PaepeFrank Speleman

Mosaic tetrasomy 15q25->qter in a newborn infant with multiple anomalies.

A VANDENENDENMR VERSCHRAEGEN-SPAENadine Van RoyW DECALUWEC DEPRAETERFranki Speleman

A1 Journal Article in AMERICAN JOURNAL OF MEDICAL GENETICS

Multiple polysomies in nasal polyps in children.

Franki SpelemanC DEPOTTERNadine Van RoyGenevieve Laureys

A1 Journal Article in CANCER GENETICS AND CYTOGENETICS

Reassignment of MYCL1 to human chromosome 1p34.3 by fluorescence in situ hybridization.

Franki SpelemanG VANCAMPNadine Van Roy

A1 Journal Article in CYTOGENETICS AND CELL GENETICS

Refined genetic and physical mapping of BPES type II

Ludwine MessiaenBart LeroySylvia De BieK De PauwNadine Van RoyFranki SpelemanG Van CampAnne De Paepe

A1 Journal Article in EUROPEAN JOURNAL OF HUMAN GENETICS

Report of the second international workshop on human chromosome 1 mapping 1995

A WeithGM BrodeurG BrunsT Cox MatiseD MischkeD NizeticMF SeldinNadine Van RoyJ Vance

Editorial material

1995

1P36 : every subband a suppressor

R VersteegH CaronNC ChengP VanderdriftR SlaterA WesterveldPA VouteO DelattreGenevieve LaureysNadine Van Roy et al.

A1 Journal Article in EUROPEAN JOURNAL OF CANCER

Assignment of the human beta-catenin gene (CTNNB1) to 3p22->p21.3 by fluorescence in situ hybridization.

J VANHENGELF NOLLETGeert BerxNadine Van RoyFranki SpelemanFrans Van Roy

A1 Journal Article in CYTOGENETICS AND CELL GENETICS

Balanced translocation in a neuroblastoma patient disrupts a cluster of small nuclear RNA UI and tRNA genes in chromosomal band Ip36

Pauline van der DriftAlvin ChanGenevieve LaureysNadine Van RoyGrace SickmannJohan den DunnenAndries WesterveldFranki SpelemanRogier Versteeg

A1 Journal Article in GENES CHROMOSOMES & CANCER

Blepharophimosis-ptosis-epicanthus inversus syndrome (BPES): clinical subtypes and their genotype

Bart LeroyLudwine MessiaenNadine Van RoyFranki SpelemanAnne De Paepe

Blepharophimosis-ptosis-epicanthus inversus syndrome (BPES): report of a large family

Bart LeroyH VermeerschFranki SpelemanNadine Van RoyL MessiaenAnne De Paepe

CONSTITUTIONAL TRANSLOCATION T(1-17)(P36.31-P36.13-Q11.2Q12.1) IN A NEUROBLASTOMA PATIENT. ESTABLISHMENT OF SOMATIC-CELL HYBRIDS AND IDENTIFICATION OF PND/A12M2 ON CHROMOSOME-1 AND NF1/SCYA7 ON CHROMOSOME-17 AS BREAKPOINT FLANKING SINGLE-COPY MARKERS.

Genevieve LaureysFranki SpelemanR VERSTEEGP VANDERDRIFTA CHANJuliaan LeroyU FRANCKEG OPDENAKKERNadine Van Roy

A1 Journal Article in ONCOGENE

Characterization of the chromosome breakpoints in a patient with a constitutional translocation T(1-17)(P36.31-P36.13-Q11.2-Q12) and neuroblastoma.

Genevieve LaureysR VERSTEEGFranki SpelemanP VANDERDRIFTU FRANCKEG OPDENAKKERNadine Van Roy

A1 Journal Article in EUROPEAN JOURNAL OF CANCER

Deletion mapping in neuroblastoma cell-lines suggests 2 distinct tumor-suppressor genes in the lp35-36 region, only one of which is associated with N-myc amplification.

NC CHENGNadine Van RoyA CHANM BEITSMAA WESTERVELDFranki SpelemanR VERSTEEG

A1 Journal Article in ONCOGENE

Full triploidy in a liveborn preterm infant.

K SMETSFranki SpelemanPiet VanhaesebrouckNadine Van RoyJo Dehoorne

A1 Journal Article in EUROPEAN JOURNAL OF PEDIATRICS

Identification of 2 distinct chromosome-12-derived amplification units in neuroblastoma cell-line NGP.

Nadine Van RoyA FORUSO MYKLEBOSTNC CHENGR VERSTEEGFranki Speleman

A1 Journal Article in CANCER GENETICS AND CYTOGENETICS

Molecular cytogenetic analysis of 1-17 translocations in neuroblastoma.

Nadine Van RoyNC CHENGGenevieve LaureysG OPDENAKKERR VERSTEEGFranki Speleman

A1 Journal Article in EUROPEAN JOURNAL OF CANCER

THE GENE FOR HUMAN GAP JUNCTION PROTEIN CONNEXIN37 (GJA4) MAPS TO CHROMOSOME 1P35.1, IN THE VICINITY OF D1S195.

G VANCAMPPaul CouckeFranki SpelemanNadine Van RoyEC BEYERBA OOSTRAPJ WILLEMS

A1 Journal Article in GENOMICS

1994

A MULTIMEGABASE CLUSTER OF SNRNA AND TRANSFER-RNA GENES ON CHROMOSOME 1P36 HARBORS AN ADENOVIRUS SV40 HYBRID VIRUS INTEGRATION SITE

P VANDERDRIFTA CHANNadine Van RoyGenevieve LaureysA WESTERVELDFranki SpelemanR VERSTEEG

A1 Journal Article in HUMAN MOLECULAR GENETICS

Direct transmission of a tandem duplication in the short arm of chromosome-8.

Catharina DhoogeNadine Van RoyMargarita CraenFranki Speleman

A1 Journal Article in CLINICAL GENETICS

HIGH-RESOLUTION FLUORESCENCE MAPPING OF 43 DNA MARKERS TO CHROMOSOME BAND-1P36

Nadine Van RoyP VANDERDRIFTGenevieve LaureysG OPDENAKKERR VERSTEEGFranki Speleman

I;17 translocations and other chromosome 17 rearrangements in human primary neuroblastoma tumors and cell lines

Nadine Van RoyGenevieve LaureysNgan Ching ChengPascale WillemGhislain OpdenakkerRogier VersteegFranki Speleman

A1 Journal Article in GENES CHROMOSOMES & CANCER

Proximal deletion of chromosome-21 confirmed by in-situ hybridization and molecular studies.

W COURTENSMB PETERSENJC NOELJ FLAMENT-DURANDN VANREGEMORTERD DELNESTEP COCHAUXMR VERSCHRAEGEN-SPAENadine Van RoyFranki Speleman et al.

A1 Journal Article in AMERICAN JOURNAL OF MEDICAL GENETICS

Recurrent I,17 translocations in human neuroblastoma reveal non-homologous recombination during the S/G2 phase as a novel mechanism for loss of heterozygosity.

H CARONP VANSLUISNadine Van RoyJ DEKRAKERFranki SpelemanPA VOUTEA WESTERVELDR SLATERR VERSTEEG

A1 Journal Article in AMERICAN JOURNAL OF HUMAN GENETICS

The human MCP-3 gene (SCYA7): cloning, sequence analysis, and assignment to the C-C chemokine gene cluster on chromosome 17ql 1.2-ql2.

G OPDENAKKERP FITENG NYSG FROYENNadine Van RoyFranki SpelemanGenevieve LaureysJ VANDAMME

A1 Journal Article in GENOMICS

1993

HIGH-RESOLUTION CHROMOSOMAL LOCALIZATION OF THE HUMAN CALCITONIN CGRP/IAPP GENE FAMILY MEMBERS.

JMN HOOVERSE REDEKERFranki SpelemanJWM HOPPENERS BHOLAJ BLIEKNadine Van RoyNJ LESCHOTA WESTERVELDM MANNENS

A1 Journal Article in GENOMICS

HIGH-RESOLUTION FLUORESCENCE MAPPING OF 46 DNA MARKERS TO THE SHORT ARM OF HUMAN CHROMOSOME-1.

Nadine Van RoyGenevieve LaureysR VERSTEEGG OPDENAKKERFranki Speleman

A1 Journal Article in GENOMICS

IMPROVED IMMUNOCYTOCHEMICAL DETECTION OF BIOTINYLATED PROBES WITH NEUTRALITE AVIDIN.

Nadine Van RoyK MANGELSCHOTSFranki Speleman

A1 Journal Article in TRENDS IN GENETICS

MOLECULAR CYTOGENETIC ANALYSIS OF A FAMILIAL PERICENTRIC-INVERSION OF CHROMOSOME-12.

Franki SpelemanNadine Van RoyE DEVOSC HILLIKERRFS SUIJKERBUIJKJuliaan Leroy

A1 Journal Article in CLINICAL GENETICS

MOLECULAR CYTOGENETIC CHARACTERIZATION OF MARKER CHROMOSOMES FOUND AT PRENATAL-DIAGNOSIS.

MR VERSCHRAEGEN-SPAENadine Van RoyA DEPERDIGOA DEPAEPEFranki Speleman

A1 Journal Article in PRENATAL DIAGNOSIS

1992

Detection of subtle reciprocal translocations by fluorescence in situ hibridization.

Franki SpelemanNadine Van RoyJ WIEGANTMR VERSCHRAEGEN-SPAEYves BenoitP GOVAERTL GOOSSENSJuliaan Leroy

A1 Journal Article in CLINICAL GENETICS

Fluorescentie in situ hybridisatie. Nieuwe mogelijkheden voor het chromosomenonderzoek.

Franki SpelemanNadine Van RoyJuliaan Leroy

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Interstitial deletion and ring chromosome derived from 19q : proximal 19q trisomy phenotype

B QuackNadine Van RoyM-R Verschraegen-SpaeF Klein

A1 Journal Article in ANNALES DE GENETIQUE

Hendrik van EgmondR VanniNadine Van RoyU LeccaFranki Speleman

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Molecular cytogenetic analysis of XX males using Y-specific DNA-sequences, including SRY

B Van der AuweraNadine Van RoyAnne De PaepeJR HawkinsI LiebaersS CastedoJ DumonFranki Speleman

A1 Journal Article in HUMAN GENETICS

Molecular cytogenetic analysis of a complex t (10;22;ll). Translocation in Ewing's sarcoma

Franki SpelemanNadine Van RoyJ WIEGANTAM DIERICKDirk UyttendaeleJG LEROY

A2 Journal Article in Genes, Chromosomes and Cancer, New York, nr. 4, pp. 188-191, 2 figg

Molecular cytogenetic analysis of a complex t(10;20;ll) translocation in Ewing's Sarcoma.

Franki SpelemanNadine Van RoyJ WIEGANTAM DIERICKDirk UyttendaeleJuliaan Leroy

A1 Journal Article in GENES CHROMOSOMES & CANCER

PUTATIVE MONOSOMY-21 IN 2 PATIENTS - CLINICAL FINDINGS AND INVESTIGATION USING FLUORESCENCE INSITU HYBRIDIZATION.

DL VILJOENFranki SpelemanR SMARTNadine Van RoyJ DUTOITJuliaan Leroy

A1 Journal Article in CLINICAL GENETICS

Platelet-derived growth factor A chain : confirmation of localization of PDGFA to chromosome 7p22 and description of an unusual minisatellite

D BonthronT CollingsKH GrzeschikNadine Van RoyFranki Speleman

A1 Journal Article in GENOMICS

Reciprocal translocation between the proximal regions of the long arms of chromosomes 13 and 15 resulting in unbalanced offspring: characterization by fluorescence in situ hybridization and DNA analysis

Kathelijne MangelschotsBernadette Van RoyFranki SpelemanNadine Van RoyJan GheuensJoke BeutenInge BuntinxMarie-Noëlle Van ThienenHerman WillekensJan Dumon et al.

A1 Journal Article in HUMAN GENETICS

Uterine leiomyoma cytogenetics, III : interphase cytogenetic analysis of karyotypically normal uterine leiomyoma excludes possibility of undetected trisomy 12

R VanniNadine Van RoyU LeccaFranki Speleman

A1 Journal Article in CANCER GENETICS AND CYTOGENETICS

1991

Is T(6-20)(P2L-QL3) a characteristic chromosome change in endometrial polyps

Franki SpelemanP DalcinNadine Van RoyE VanmarckP BuytaertH VandenbergheJG Leroy

A1 Journal Article in GENES CHROMOSOMES & CANCER

Pallister-Killian syndrome: characterization of the isochromosome 12p by fluorescent in situ hybridization

Franki SpelemanJuliaan LeroyNadine Van RoyAnne De PaepeR SuukerbuukJ BrunnerL LooijengaM Verschraegen-SpaeE Orye

A1 Journal Article in AMERICAN JOURNAL OF MEDICAL GENETICS

Ip36: every subband a suppressor ? Eur. J. Cancer, 1995, 31 A, 538-540.

R VERSTEEGH CARONNC CHENGP VAN DER DRIFTR SLATERA WESTERVELDPA VOUTEO DELATTREGenevieve LaureysNadine Van Roy et al.

A2 Journal Article