Research Explorer

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Researcher

Nadia Bougarne

Awards & Distinctions

24 Results

2019

Mechanisms underlying the functional cooperation between PPARα and GRα to attenuate inflammatory responses

Nadia BougarneViacheslav MylkaDariusz RatmanIlse BeckJonathan ThommisLode De CauwerJan TavernierBart StaelsClaude LibertKarolien De Bosscher

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2018

Co-activation of glucocorticoid receptor and peroxisome proliferator-activated receptor-γ in murine skin prevents worsening of atopic march

Julie DeckersNadia BougarneViacheslav MylkaSofie DesmetAstrid LuypaertMichael DevosGiel TangheJustine Van MoorleghemManon VanheerswynghelsLode De Cauwer et al.

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

Molecular actions of PPARα in lipid metabolism and inflammation

Nadia BougarneBasiel WeyersSofie DesmetJulie DeckersDavid W RayBart StaelsKarolien De Bosscher

A1 Journal Article in ENDOCRINE REVIEWS

2017

Compound A influences gene regulation of the dexamethasone-activated glucocorticoid receptor by alternative cofactor recruitment

Sofie DesmetNadia BougarneLaura Van MoortelLode De CauwerJonathan ThommisM VuylstekeDariusz RatmanR HoutmanJan TavernierKarolien De Bosscher

A1 Journal Article in SCIENTIFIC REPORTS

Glucocorticoid receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor

Ioanna PettaNadia BougarneJolien VandewalleLien DejagerSofie VandevyverMarlies BallegeerSofie DesmetJonathan ThommisLode De CauwerSam Lievens et al.

A1 Journal Article in SCIENTIFIC REPORTS

Involvement of the glucocorticoid receptor in pro-inflammatory transcription factor inhibition by daucane esters from Laserpitium zernyi

Visnja PopovicJan GoemanNadia BougarneSven EyckermanArne HeyerickKarolien De BosscherJohan Van der Eycken

A1 Journal Article in JOURNAL OF NATURAL PRODUCTS

Selective glucocorticoid receptor properties of GSK866 analogs with cysteine reactive warheads

Chandra S ChirumamillaAjay PalaganiBalu KamarajKen DeclerckMarinus WC VerbeekOksana RyabtsovaKarolien De BosscherNadia BougarneBart RuttensKris Gevaert et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2016

Chromatin recruitment of activated AMPK drives fasting response genes co-controlled by GR and PPARα

Dariusz RatmanViacheslav MylkaNadia BougarneMichal PawlakSandrine CaronNathalie HennuyerRéjane PaumelleLode De CauwerJonathan ThommisMark H Rider et al.

A1 Journal Article in NUCLEIC ACIDS RESEARCH

2015

Inhibition of the NF-κB signaling pathway by a novel heterocyclic curcumin analogue

Anna-Maria KatsoriAjay PalaganiNadia BougarneDimitra Hadjipavlou-LitinaGuy HaegemanWim Vanden Berghe

A1 Journal Article in MOLECULES

Novel anti-inflammatory daucane esters from Laserpitium zernyi Hayek (Apiaceae)

Visnja PopovicJan GoemanNadia BougarneArne HeyerickKarolien De BosscherJohan Van der Eycken

Synthesis of benzothiophene-based hydroxamic acids as potent and selective HDAC6 inhibitors

Rob De VreeseNicholas Van SteenTom VerhaegheTom DesmetNadia BougarneKarolien De BosscherVeronick BenoyWanda HaeckLudo Van Den BoschMatthias D'hooghe

A1 Journal Article in CHEMICAL COMMUNICATIONS

2014

Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-κB and AP-1

Karolien De BosscherIlse BeckLien DejagerNadia BougarneAnthoula GaigneauxSebastien ChateauvieuxDariusz RatmanMarc BrackeJan TavernierWim Vanden Berghe et al.

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

Sesquiterpenes from selected Laserpitium L. species as antimicrobial agents

Visnja PopovicDejan StojkovicMilos NikolicNadia BougarneJan GoemanArne HeyerickKarolien De BosscherMarina SokovicJohan Van der Eycken

The increasing complexity of glucocorticoid receptor signaling and regulation

Sofie DesmetIlse BeckNadia BougarneDorien ClarisseJulie DeckersDariusz RatmanJan TavernierKarolien De Bosscher

A2 Journal Article in PROCEEDINGS OF THE BELGIAN ROYAL ACADEMIES OF MEDICINE

2013

Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation

Ilse BeckZuzanna DrebertRuben Hoya-AriasAli A BaharMichael DevosDorien ClarisseSofie DesmetNadia BougarneBart RuttensValerie Gossye et al.

A1 Journal Article in PLOS ONE

Mitogen- and stress-activated protein kinase 1 (MSK1) regulates glucocorticoid response element (GRE) promoter activity in a glucocorticoid concentration-dependent manner

Ilse BeckDorien ClarisseNadia BougarneSam OkretGuy HaegemanKarolien De Bosscher

Mitogen- and stress-activated protein kinase 1 MSK1 regulates glucocorticoid response element promoter activity in a glucocorticoid concentration-dependent manner

Ilse BeckDorien ClarisseNadia BougarneSam OkretGuy HaegemanKarolien De Bosscher

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACOLOGY

2011

Gallic acid indanone and mangiferin xanthone are strong determinants of immunosuppressive anti-tumour effects of Mangifera indica L. bark in MDA-MB231 breast cancer cells

Dagmar Garcia-RiveraRene DelgadoNadia BougarneGuy HaegemanWim Vanden Berghe

A1 Journal Article in CANCER LETTERS

2010

Antiinflammatory Properties of a Plant-Derived Nonsteroidal, Dissociated Glucocorticoid Receptor Modulator in Experimental Autoimmune Encephalomyelitis

Geert van LooMozes SzeNadia BougarneJelle PraetConor Mc GuireAndrea UllrichGuy HaegemanMarco PrinzRudi BeyaertKarolien De Bosscher

A1 Journal Article in MOLECULAR ENDOCRINOLOGY

2009

Circumventing glucocorticoid-mediated hyperinsulinemia via the activation of PPAR alpha

Nadia BougarneRejane PaumelleGuy HaegemanBart StaelsKarolien De Bosscher

Editorial material

Differential mechanism of NF-κB inhibition by two glucocorticoid receptor modulators in rheumatoid arthritis synovial fibroblasts

Valerie GossyeDirk ElewautNadia BougarneDebby BrackeSerge Van CalenberghGuy HaegemanKarolien De Bosscher

A1 Journal Article in ARTHRITIS AND RHEUMATISM

Glucocorticoids and mitogen- and stress-activated protein kinase 1 inhibitors: Possible partners in the combat against inflammation

Ilse BeckWim Vanden BergheSarah GerloNadia BougarneLinda VermeulenKarolien De BosscherGuy Haegeman

A1 Journal Article in BIOCHEMICAL PHARMACOLOGY

PPAR alpha blocks glucocorticoid receptor alpha-mediated transactivation but cooperates with the activated glucocorticoid receptor alpha for transrepression on NF-kappa B

Nadia BougarneRejane PaumelleSandrine CaronNathalie HennuyerRoxane MansouriPhilippe GervoisBart StaelsGuy HaegemanKarolien De Bosscher

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2008

Altered subcellular distribution of MSK1 induced by glucocorticoids contributes to NF-kappa B inhibition

Ilse BeckWim Vanden BergheLinda VermeulenNadia BougarneBERT VANDER CRUYSSENGuy HaegemanKarolien De Bosscher

A1 Journal Article in EMBO JOURNAL