Manage settings
MENU
About this site
In het Nederlands
Home
Researchers
Projects
Organisations
Publications
Infrastructure
Contact
Research Explorer
Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.
Researcher
Monique Willart
Profile
Projects
Publications
Activities
Awards & Distinctions
57
Results
2017
House dust mite-driven asthma and allergen-specific T cells depend on B cells when the amount of inhaled allergen is limiting
Melissa Dullaers
Martijn Schuijs
Monique Willart
Kaat Fierens
Justine Van Moorleghem
Hamida Hammad
Bart Lambrecht
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2017
Inflammatory monocytes regulate Th1 oriented immunity to CpG adjuvanted protein vaccines through production of IL-12
Stefaan De Koker
Lien Van Hoecke
Ans De Beuckelaer
Kenny Roose
Kim Deswarte
Monique Willart
Pieter Bogaert
Thomas Naessens
Bruno De Geest
Xavier Saelens
et al.
A1
Journal Article
in
SCIENTIFIC REPORTS
2017
2016
A20 deficiency in lung epithelial cells protects against influenza A virus infection
Jonathan Maelfait
Kenny Roose
Lars Vereecke
Conor Mc Guire
Mozes Sze
Martijn Schuijs
Monique Willart
Lorena Ibanez
Hamida Hammad
Bart Lambrecht
et al.
A1
Journal Article
in
PLOS PATHOGENS
2016
Cholesterol-sensing liver X receptors stimulate Th2-driven allergic eosinophilic asthma in mice
Muriel Smet
Lien Van Hoecke
Ans De Beuckelaer
Seppe Vander Beken
Thomas Naessens
Karl Vergote
Monique Willart
Bart Lambrecht
Jan-Ake Gustafsson
Knut R Steffensen
et al.
A2
Journal Article
in
IMMUNITY INFLAMMATION AND DISEASE
2016
GM-CSF treatment prevents respiratory syncytial virus– induced pulmonary exacerbation responses in postallergic mice by stimulating alveolar macrophage maturation
Thomas Naessens
Bert Schepens
Muriel Smet
Charlotte Pollard
Lien Van Hoecke
Ans De Beuckelaer
Monique Willart
Bart Lambrecht
Stefaan De Koker
Xavier Saelens
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2016
Perinatal activation of the interleukin-33 pathway promotes type 2 immunity in the developing lung
Ismé De Kleer
Mirjam Kool
Marjolein JW de Bruijn
Monique Willart
Justine Van Moorleghem
Martijn Schuijs
Maud Plantinga
Rudi Beyaert
Emily Hams
Padraic G Fallon
et al.
A1
Journal Article
in
IMMUNITY
2016
2015
Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells
Martijn Schuijs
Monique Willart
Karl Vergote
Delphine Gras
Kim Deswarte
Markus J Ege
Filipe Branco Madeira
Rudi Beyaert
Geert van Loo
Franz Bracher
et al.
A1
Journal Article
in
SCIENCE
2015
Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation
Lien Dejager
Karen Dendoncker
Melanie Eggermont
Jolien Souffriau
Filip Van Hauwermeiren
Monique Willart
Elien Van Wonterghem
Thomas Naessens
Marlies Ballegeer
Sofie Vandevyver
et al.
A1
Journal Article
in
MUCOSAL IMMUNOLOGY
2015
2013
Cytokine targets in airway inflammation
Martijn Schuijs
Monique Willart
Hamida Hammad
Bart Lambrecht
A1
Journal Article
in
CURRENT OPINION IN PHARMACOLOGY
2013
Immune activation at the lung epithelial barrier
Monique Willart
Hamida Hammad
Bart Lambrecht
Dissertation
2013
PAMPs and DAMPs in allergy exacerbation models
Monique Willart
Philippe Poulliot
Bart Lambrecht
Mirjam Kool
Bookchapter
in
Mouse models in allergic disease : methods and protocols
2013
The mucosal adjuvant cholera toxin B instructs non-mucosal dendritic cells to promote IgA production via retinoic acid and TGF-β
Anouk K Gloudemans
Maud Plantinga
Martin Guilliams
Monique Willart
Arifa Ozir-Fazalalikhan
Alwin van der Ham
Louis Boon
Nicola L Harris
Hamida Hammad
Henk C Hoogsteden
et al.
A1
Journal Article
in
PLOS ONE
2013
2012
Contribution of regulatory T cells to alleviation of experimental allergic asthma after specific immunotherapy
H Maazi
S Shirinbak
Monique Willart
Hamida Hammad
M Cabanski
L Boon
V Ganesh
AM Baru
G Hansen
Bart Lambrecht
et al.
A1
Journal Article
in
CLINICAL AND EXPERIMENTAL ALLERGY
2012
Interleukin-1α controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33
Monique Willart
Kim Deswarte
Philippe Pouliot
Harald Braun
Rudi Beyaert
Bart Lambrecht
Hamida Hammad
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2012
Polymeric multilayer capsule-mediated vaccination induces protective immunity against cancer and viral infection
Bruno De Geest
Monique Willart
Hamida Hammad
Bart Lambrecht
Charlotte Pollard
Pieter Bogaert
Marina De Filette
Xavier Saelens
Chris Vervaet
Jean Paul Remon
et al.
A1
Journal Article
in
ACS NANO
2012
Surface-engineered polyelectrolyte multilayer capsules: synthetic vaccines mimicking microbial structure and function
Bruno De Geest
Monique Willart
Bart Lambrecht
Charlotte Pollard
Chris Vervaet
Jean Paul Remon
Johan Grooten
Stefaan De Koker
A1
Journal Article
in
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
2012
Ursodeoxycholic acid suppresses eosinophilic airway inflammation by inhibiting the function of dendritic cells through the nuclear farnesoid X receptor
Monique Willart
M van Nimwegen
A Grefhorst
Hamida Hammad
L Moons
HC Hoogsteden
Bart Lambrecht
A KleinJan
A1
Journal Article
in
ALLERGY
2012
2011
An unexpected role for uric Acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthma
Mirjam Kool
Monique Willart
Menno van Nimwegen
Ingrid Bergen
Philippe Pouliot
J Christian Virchow
Neil Rogers
Fabiola Osorio
Caetano Reis E Sousa
Hamida Hammad
et al.
A1
Journal Article
in
IMMUNITY
2011
Designing polymeric particles for antigen delivery
Stefaan De Koker
Bart Lambrecht
Monique Willart
Yvette van Kooyk
Johan Grooten
Chris Vervaet
Jean Paul Remon
Bruno De Geest
A1
Journal Article
in
CHEMICAL SOCIETY REVIEWS
2011
Disruption of the SapM locus in Mycobacterium bovis BCG improves its protective efficacy as a vaccine against M. tuberculosis
Nele Festjens
Pieter Bogaert
Anjana Batni
Erica Houthuys
Evelyn Plets
Dieter Vanderschaeghe
Bram Laukens
Bob Asselbergh
Eef Parthoens
Riet De Rycke
et al.
A1
Journal Article
in
EMBO MOLECULAR MEDICINE
2011
Dual role of IL-22 in allergic airway inflammation and its cross-talk with IL-17A
Anne-Gaelle Besnard
Robert Sabat
Laure Dumoutier
Jean-Christophe Renauld
Monique Willart
Bart Lambrecht
Mauro M Teixeira
Sabine Charron
Lizette Fick
Francois Erard
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2011
Lung dendritic cell-epithelial cell crosstalk in Th2 responses to allergens
Monique Willart
Hamida Hammad
A1
Journal Article
in
CURRENT OPINION IN IMMUNOLOGY
2011
Novel anti-inflammatory drugs based on targeting lung dendritic cells and airway epithelial cells
Bart Lambrecht
Maud Plantinga
Monique Willart
Hamida Hammad
Bookchapter
in
Inflammation and allergy drug design
2011
Persistent activation of dendritic cells after resolution of allergic airway inflammation breaks tolerance to inhaled allergens in mice
Leonie van Rijt
Nanda Vos
Monique Willart
Femke Muskens
Paul P Tak
Corine van der Horst
Henk C Hoogsteden
Bart Lambrecht
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2011
The neuropeptide calcitonin gene-related peptide affects allergic airway inflammation by modulating dendritic cell function
S Rochlitzer
TZ Veres
K Kühne
F Prenzler
C Pilzner
S Knothe
C Winkler
HD Lauenstein
Monique Willart
Hamida Hammad
et al.
A1
Journal Article
in
CLINICAL AND EXPERIMENTAL ALLERGY
2011
2010
Diesel exhaust particles stimulate adaptive immunity by acting on pulmonary dendritic cells
Sharen Provoost
Tania Maes
Monique Willart
Guy Joos
Bart Lambrecht
Kurt Tournoy
A1
Journal Article
in
Journal of Immunology
2010
Inflammatory dendritic cells - not basophils - are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen
Hamida Hammad
Maud Plantinga
Kim Deswarte
Philippe Pouliot
Monique Willart
Mirjam Kool
Femke Muskens
Bart Lambrecht
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2010
Lentiviral gene therapy of murine hematopoietic stem cells ameliorates the Pompe disease phenotype
Niek P van Til
Merel Stok
Fatima SF Aerts Kaya
Monique C de Waard
Elnaz Farahbakhshian
Trudi P Visser
Marian A Kroos
Edwin H Jacobs
Monique Willart
Pascal van der Wegen
et al.
A1
Journal Article
in
BLOOD
2010
Studying the function of dendritic cells in mouse models of asthma
Philippe Pouliot
Monique Willart
Hamida Hammad
Bart Lambrecht
Bookchapter
in
Dendritic cell protocols
2010
United airways: circulating Th2 effector cells in an allergic rhinitis model are responsible for promoting lower airways inflammation
Alex Kleinjan
Monique Willart
Menno van Nimwegen
Karolina Leman
Henk Hoogsteden
Rudy Hendriks
Bart Lambrecht
A1
Journal Article
in
CLINICAL AND EXPERIMENTAL ALLERGY
2010
2009
An anti-inflammatory role for plasmacytoid dendritic cells in allergic airway inflammation
Mirjam Kool
Menno van Nimwegen
Monique Willart
Femke Muskens
Louis Boon
Joost Smit
Anthony Coyle
Björn Clausen
Henk Hoogsteden
Bart Lambrecht
et al.
A1
Journal Article
in
JOURNAL OF IMMUNOLOGY
2009
Cholera toxin B suppresses allergic inflammation through induction of secretory IgA
H. Smits
A. Gloudemans
M. van Nimwegen
Monique Willart
T. Soullié
F. Muskens
E. de Jong
L. Boon
C. Pilette
F.-E. Johansen
et al.
A1
Journal Article
in
Mucosal Immunology
2009
Chronic airway inflammation promotes de novo sensitisation to inhaled allergens by persistent activation of dendritic cells
L van Rijt
N Vos
F Muskens
Monique Willart
H Hoogsteden
Bart Lambrecht
C3
Conference
2009
Chronic airway inflammation promotes de novo sensitization to inhaled allergen by persistent activation of dendritic cells
LS Van Rijt
N Vos
Monique Willart
F Muskens
H Hoogsteden
Bart Lambrecht
C3
Conference
2009
De rol van de dendritische cel in astma
Monique Willart
Bart Lambrecht
A4
Journal Article
in
TIJDSCHRIFT VAN DE BELGISCHE VERENIGING VAN LABORATORIUM-TECHNOLOGEN = REVUE DE L'ASSOCIATION BELGE DES TECHNOLOGUES DE LABORATOIRE
2009
Dendritic cells are crucial for maintenance of tertiary lymphoid structures in the lung of influenza virus-infected mice
Corine H GeurtsvanKessel
Monique Willart
Ingrid M Bergen
Leonie S van Rijt
Femke Muskens
Dirk Elewaut
Albert DLE Osterhaus
Rudi Hendriks
Guus F Rimmelzwaan
Bart Lambrecht
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2009
House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells
Hamida Hammad
Marcello Chieppa
Frédèric Perros
Monique Willart
Ronald Germain
Bart Lambrecht
A1
Journal Article
in
Nature Medicine
2009
Immune Suppression Feature of Ursodeoxycholic Acid is DC-mediated as Measured in Eosinophilic Airway Inflammation Model
A. Kleinjan
Monique Willart
Hamida Hammad
M. van Nimwegen
L. Moons
H.C. Hoogsteden
Bart Lambrecht
C3
Conference
2009
Mechanism of action of clinically approved adjuvants
Bart Lambrecht
Mirjam Kool
Monique Willart
Hamida Hammad
A1
Journal Article
in
Current opinion in Immunology
2009
Sensitization by intratracheally injected dendritic cells is independent of antigen presentation by host antigen-presenting cells
Harmjan Kuipers
Thomas Soullie
Hamida Hammad
Monique Willart
Mirjam Kool
Danielle Hijdra
Henk Hoogsteden
Bart Lambrecht
A1
Journal Article
in
JOURNAL OF LEUKOCYTE BIOLOGY
2009
The danger within: endogenous danger signals, atopy and asthma
Monique Willart
Bart Lambrecht
A1
Journal Article
in
Clinical and Experimental Allergy
2009
The lung vascular filter as a site of immune induction for T cell responses to large embolic antigen
Monique Willart
Hendrik Jan de Heer
Hamida Hammad
Thomas Soullié
Kim Deswarte
Björn E Clausen
Louis Boon
Henk C Hoogsteden
Bart Lambrecht
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2009
2008
'United airways': Allergic rhinitis exacerbates lower airway inflammation is controlled by cellular and neurogenic processes in a mouse model
A KLEINJAN
Monique Willart
K LEMAN
HC HOOGSTEDEN
Bart Lambrecht
C3
Conference
2008
Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells
M KOOL
T SOULLIE
M VAN NIMWEGEN
Monique Willart
F MUSKENS
S JUNG
HC HOOGSTEDEN
Hamida Hammad
Bart Lambrecht
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2008
Clearance of influenza virus from the lung depends on migratory langerin(+)CD11b(-) but not plasmacytoid dendritic cells
CH GEURTSVANKESSEL
Monique Willart
LS VAN RIJT
F MUSKENS
M KOOL
C BAAS
K THIELEMANS
C BENNETT
BE CLASEN
HC HOOGSTEDEN
et al.
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2008
De rol van de dendritische cel in astma
Monique Willart
Bart Lambrecht
A4
Journal Article
in
Analyse
2008
De rol van de dendritische cel in astma
Monique Willart
Bart Lambrecht
A3
Journal Article
in
Nederlands tijdschrift voor klinische chemie en laboratoriumgeneeskunde
2008
Inducible costimulator blockade prolongs airway lumnal patency in a mouse model of obliterative bronchiolitis
Alex KleinJan
Monique Willart
Harmjan Kuipers
Anthony J. Coyle
Henk C. Hoogsteden
Bart Lambrecht
A1
Journal Article
in
Transplantation
2008
2007
Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells
M IDZKO
Hamida Hammad
M VAN NIMWEGEN
M KOOL
Monique Willart
F MUSKENS
HC HOOGSTEDEN
W LUTTMANN
D FERRARI
F DI VIRGILIO
et al.
A1
Journal Article
in
NATURE MEDICINE
2007
Protective effect of Schistosoma mansoni infection on allergic airway inflammation depends on the intensity and chronicity of infection
Hermehin H. Smits
Hamida Hammad
Menno van Nimwegen
Thomas Soullie
Monique Willart
Ellen Lievers
Jonathan Kadouch
Mirjam Kool
Janneke Kos-van Oosterhoud
Andre M. Deelder
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2007
2006
An essential role for dendritic cells in human and experimental allergic rhinitis
A KLEINJAN
Monique Willart
LS VAN RIJT
GJ BRAUNSTAHL
K LEMAN
S JUNG
HC HOOGSTEDEN
Bart Lambrecht
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2006
Contribution of the PD-1 ligands/PD-1 signaling pathway to dendritic cell-mediated CD4(+) T cell activation
H KUIPERS
F MUSKENS
Monique Willart
D HIJDRA
FBJ VAN ASSEMA
AJ COYLE
HC HOOGSTEDEN
Bart Lambrecht
A1
Journal Article
in
EUROPEAN JOURNAL OF IMMUNOLOGY
2006
Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function
M IDZKO
Hamida Hammad
M VAN NIMWEGEN
M KOOL
T MULLER
T SOULLIE
Monique Willart
D HIJDRA
HC HOOGSTEDEN
Bart Lambrecht
A1
Journal Article
in
JOURNAL OF CLINICAL INVESTIGATION
2006
2005
In vivo depletion of lung CD11c(+) dendritic cells during allergen challenge abrogates the characteristic features of asthma
LS VAN RIJT
S JUNG
A KLEINJAN
N VOS
Monique Willart
C DUEZ
HC HOOGSTEDEN
Bart Lambrecht
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2005
2004
Dendritic cells retrovirally overexpressing IL-12 induce strong Th1 responses to inhaled antigen in the lung but fail to revert established Th2 sensitization
H KUIPERS
C HEIRMAN
D HIJDRA
F MUSKENS
Monique Willart
S VAN MEIRVENNE
K THIELEMANS
HC HOOGSTEDEN
Bart Lambrecht
A1
Journal Article
in
JOURNAL OF LEUKOCYTE BIOLOGY
2004
Essential role of dendritic cell CD80/86 costimulation in the induction, but not reactivation, of T(H)2 effector responses in a mouse model of asthma
LS VAN RIFT
N VOS
Monique Willart
A KLEINJAN
AJ COYLE
HC HOOGSTEDEN
Bart Lambrecht
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2004
Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen
HJ DE HEER
Hamida Hammad
T SOULLIE
D HIJDRA
N VOS
Monique Willart
HC HOOGSTEDEN
Bart Lambrecht
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL MEDICINE
2004