Research Explorer

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Researcher

Mina Popovic

Awards & Distinctions

45 Results

2023

Retained chromosomal integrity following CRISPR-Cas9-based mutational correction in human embryos

Bieke BekaertAnnekatrien BoelLisa De WitteWinter VandenbergheMina PopovicPanagiotis StamatiadisGwenny CosemansLise TordeursAthina-Maria De LooreSusana Marina Chuva de Sousa Lopes et al.

A1 Journal Article in MOLECULAR THERAPY

2022

Human germline nuclear transfer to overcome mitochondrial disease and failed fertilization after ICSI

Maoxing TangAnnekatrien BoelNoemi CastelluccioArantxa Cardona BarberánAntonia ChristodoulakiBieke BekaertMina PopovicFrauke Vanden MeerschautPetra De SutterBjörn Menten et al.

A1 Journal Article in JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

2021

Activin A-derived human embryonic stem cells show increased competence to differentiate into primordial germ cell-like cells

Swati MishraJasin TaelmanMina PopovicLaurentijn TillemanEvi DuthooMargot Van der JeughtDieter DeforceFilip Van NieuwerburghBjörn MentenPetra De Sutter et al.

A1 Journal Article in STEM CELLS

Comparative analysis of mouse and human preimplantation development following POU5F1 CRISPR/Cas9 targeting reveals interspecies differences

Panagiotis StamatiadisAnnekatrien BoelGwenny CosemansMina PopovicBieke BekaertRamesh Reddy GuggillaMaoxing TangPetra De SutterFilip Van NieuwerburghBjörn Menten et al.

A1 Journal Article in HUMAN REPRODUCTION

Correcting a PLCζ mutation in the human germ line to overcome hereditary infertility

Bieke BekaertAnnekatrien BoelMina PopovicPanagiotis StamatiadisS M Chuva de Sousa LopesPetra De SutterBjörn MentenDominic StoopPaul CouckeBjörn Heindryckx

Recurrent chromosomal imbalances provide selective advantage to human embryonic stem cells under enhanced replicative stress conditions

Liselot MusStéphane Van HaverMina PopovicWim TrypsteenSteve LefeverNadja ZeltnerYudelca OgandoEva JacobsGeertrui DeneckerEllen Sanders et al.

A1 Journal Article in GENES CHROMOSOMES & CANCER

Strand-specific single-cell methylomics reveals distinct modes of DNA demethylation dynamics during early mammalian development

Maya SenDylan MooijmanAlex ChialastriJean-Charles BoissetMina PopovicBjörn HeindryckxSusana Marina Chuva de Sousa LopesSiddharth S. DeyAlexander van Oudenaarden

A1 Journal Article in NATURE COMMUNICATIONS

2020

A proof-of-concept study to investigate DNA repair mechanisms in the human embryo after the application of CRISPR/Cas9 gene editing in the germ line

Bieke BekaertAnnekatrien BoelLisa De WitteMina PopovicRamesh Reddy GuggillaSwati MishraGwenny CosemansLise TordeursSusana Marina Chuva de Sousa LopesPetra De Sutter et al.

Chromosomal mosaicism in human blastocysts : the ultimate diagnostic dilemma

Mina PopovicLien DhaenensAnnekatrien BoelBjörn MentenBjörn Heindryckx

A1 Journal Article in HUMAN REPRODUCTION UPDATE

Chromosomal mosaicism in human blastocysts : the ultimate diagnostic dilemma (vol 26, pg 313, 2020)

Mina PopovicLien DhaenensAnnekatrien BoelBjörn MentenBjörn Heindryckx

Correcting a PLCζ mutation in the human germ line to overcome hereditary infertility

Bieke BekaertAnnekatrien BoelMina PopovicPanagiotis StamatiadisSusana Marina Chuva de Sousa LopesPetra De SutterPaul CouckeBjörn Heindryckx

Germline nuclear transfer in mice may rescue poor embryo development associated with advanced maternal age and early embryo arrest

Maoxing TangMina PopovicPanagiotis StamatiadisMargot Van der JeughtRudy Van CosterDieter DeforcePetra De SutterPaul CouckeBjörn MentenDominic Stoop et al.

A1 Journal Article in HUMAN REPRODUCTION

Modelling human embryogenesis : embryo-like structures spark ethical and policy debate

AM Pereira DaoudMina PopovicWJ DondorpM Trani BustosAL BredenoordSusana Marina Chuva de Sousa LopesSC van den BrinkRoelen BAJde Wert GMWRBjörn Heindryckx

A1 Journal Article in HUMAN REPRODUCTION UPDATE

2019

17q gain provides proliferative advantage to human embryonic stem cells under conditions of replicative stress

Liselot MusGeertrui DeneckerStéphane Van HaverNadja ZeltnerYudelca OgandoEllen SandersEva JacobsMina PopovicChristophe Van NesteSuzanne Vanhauwaert et al.

17q gain provides proliferative advantage to human embryonic stem cells under replicative stress

Liselot MusStéphane Van HaverGeertrui DeneckerNadja ZeltnerYudelca OgandoEllen SandersEva JacobsMina PopovicChristophe Van NesteSuzanne Vanhauwaert et al.

Assisted oocyte activation significantly increases fertilization and pregnancy outcome in patients with low and total failed fertilization after intracytoplasmic sperm injection : a 17-year retrospective study

Davina BonteMinerva Ferrer BuitragoLien DhaenensMina PopovicVanessa ThysIlse De CrooStefanie De GheselleNathalie SteyaertAnnekatrien BoelFrauke Vanden Meerschaut et al.

A1 Journal Article in FERTILITY AND STERILITY

Comparative analysis of different nuclear transfer techniques to prevent the transmission of mitochondrial DNA variants

Maoxing TangRamesh Reddy GuggillaYannick GansemansMargot Van der JeughtAnnekatrien BoelMina PopovicPanagiotis StamatiadisMinerva Ferrer BuitragoVanessa ThysRudy Van Coster et al.

A1 Journal Article in MOLECULAR HUMAN REPRODUCTION

Exploring the contribution of gene dosage effects of 17q gain genes on hESC and neuroblastoma proliferation

Liselot MusGeertrui DeneckerStéphane Van HaverNadja ZeltnerYudelca OgandoEllen SandersEva JacobsMina PopovicChristophe Van NesteSuzanne Vanhauwaert et al.

Extended in vitro culture of human embryos demonstrates the complex nature of diagnosing chromosomal mosaicism from a single trophectoderm biopsy

Mina PopovicL. DhaenensJ. TaelmanAnnelies DheedeneM. BialeckaPetra De SutterS. M. Chuva de Sousa LopesBjörn MentenBjörn Heindryckx

A1 Journal Article in HUMAN REPRODUCTION

Human blastocyst outgrowths recapitulate primordial germ cell specification events

Mina PopovicMonika BialeckaMaria Gomes FernandesJasin TaelmanMargot Van der JeughtPetra De SutterBjörn HeindryckxSusana Marina Chuva de Sousa Lopes

A1 Journal Article in MOLECULAR HUMAN REPRODUCTION

Increased primordial germ cell (PGC) specification from human embryonic stem cells (hESC) derived in Activin A

Swati MishraMargot Van der JeughtMina PopovicJasin TaelmanEvi DuthooKatarzyna Szymańska-VandendriesschePetra De SutterLaurentijn TillemanFilip Van NieuwerburghAnnekatrien Boel et al.

Intracellular localisation of platelet-activating factor during mammalian embryo development in vitro : a comparison of cattle, mouse and human

Lynn VandenbergheBjörn HeindryckxKatrien SmitsMina PopovicKatarzyna Szymańska-VandendriesscheDavina BonteLuc PeelmanDieter DeforcePetra De SutterAnn Van Soom et al.

A1 Journal Article in REPRODUCTION FERTILITY AND DEVELOPMENT

Losing balance : investigating the prevalence and impact of chromosomal instability during early human development

Mina PopovicBjörn HeindryckxPetra De Sutter

Robust protocol for feeder-free adaptation of cryopreserved human pluripotent stem cells

Jeffrey AaldersNatasja Van den VrekenMina PopovicSwati MishraBjörn HeindryckxJolanda van Hengel

A1 Journal Article in IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Two decades of embryonic stem cells : a historical overview

Cristina EguizabalBegoña AranSusana Marina Chuva de Sousa LopesM. GeensBjörn HeindryckxS. PanulaMina PopovicRita VassenaAnna Veiga

A1 Journal Article in HUMAN REPRODUCTION OPEN

Untargeted histone profiling during naive conversion uncovers conserved modification markers between mouse and human

Laura De ClerckJasin TaelmanMina PopovicSander WillemsMargot Van der JeughtBjörn HeindryckxPetra De SutterHendrik MarksDieter DeforceMaarten Dhaenens

A1 Journal Article in SCIENTIFIC REPORTS

WNT inhibition and increased fibroblast growth factor signaling promotes derivation of less heterogeneous primed human embryonic stem cells, compatible with differentiation

Jasin TaelmanMina PopovicMonika BialeckaLaurentijn TillemanSharat WarrierMargot Van der JeughtBjörn MentenDieter DeforcePetra De SutterFilip Van Nieuwerburgh et al.

A1 Journal Article in STEM CELLS AND DEVELOPMENT

2018

Chromosomal mosaicism in human blastocysts : the ultimate challenge of preimplantation genetic testing?

Mina PopovicAnnelies DheedeneCHRISTODOULOS CHRISTODOULOUJasin TaelmanLien DhaenensFilip Van NieuwerburghDieter DeforceEtienne Van den AbbeelPetra De SutterBjörn Menten et al.

A1 Journal Article in HUMAN REPRODUCTION

Comparative analysis of naive, primed and ground state pluripotency in mouse embryonic stem cells originating from the same genetic background

Sabitri GhimireMargot Van der JeughtJitesh NeupaneMatthias S RoostJasper AnckaertMina PopovicFilip Van NieuwerburghPieter MestdaghJo VandesompeleDieter Deforce et al.

A1 Journal Article in SCIENTIFIC REPORTS

Culture conditions affect Ca2+ release in artificially activated mouse and human oocytes

Yuechao LuDavina BonteMinerva Ferrer BuitragoMina PopovicJitesh NeupaneMargot Van der JeughtLuc LeybaertPetra De SutterBjörn Heindryckx

A1 Journal Article in REPRODUCTION FERTILITY AND DEVELOPMENT

Exploring the contribution of gene dosage effects of 17Q gain on ESC and neuroblastoma proliferation

Liselot MusGeertrui DeneckerNadja ZeltnerYudelca OgandoStéphane Van HaverEllen SandersEva JacobsMina PopovicChristophe Van NesteSuzanne Vanhauwaert et al.

Exploring the contribution of gene dosage effects of 17q gain genes on hESC and neuroblastoma proliferation

Liselot MusGeertrui DeneckerStéphane Van HaverNadja ZeltnerYudelca OgandoEllen SandersEva JacobsMina PopovicChristophe Van NesteSuzanne Vanhauwaert et al.

Exploring the contribution of gene dosage effects of 17q gain on ESC and neuroblastoma proliferation

Liselot MusGeertrui DeneckerNadja ZeltnerYudelca OgandoStéphane Van HaverEllen SandersEva JacobsMina PopovicChristophe Van NesteSuzanne Vanhauwaert et al.

Exploring the contribution of gene dosage effects of 17q gain on ESC and neuroblastoma proliferation

Liselot MusGeertrui DeneckerNadja ZeltnerYudelca OgandoStéphane Van HaverEllen SandersEva JacobsMina PopovicChristophe Van NesteSuzanne Vanhauwaert et al.

Impact of pluripotency state and Activin A supplementation on derivation of primordial germ cell-like cells from human

Swati MishraMargot Van der JeughtJasin TaelmanMina PopovicKatarzyna Szymańska-VandendriesscheDieter DeforcePetra De SutterSusana Marina Chuva de Sousa LopesBjörn Heindryckx

Patients with a high proportion of immature and meiotically resistant oocytes experience defective nuclear oocyte maturation patterns and impaired pregnancy outcomes

Yuechao LuMinerva Ferrer BuitragoMina PopovicJitesh NeupaneWinnok De VosSylvie LiermanEtienne Van den AbbeelMargot Van der JeughtDimitra NikiforakiPetra De Sutter et al.

A1 Journal Article in REPRODUCTIVE BIOMEDICINE ONLINE

Transcriptional landscape changes during human embryonic stem cell derivation

Sharat WarrierJasin TaelmanLaurentijn TillemanMargot Van der JeughtGalbha DuggalSylvie LiermanMina PopovicAnn Van SoomLuc PeelmanFilip Van Nieuwerburgh et al.

A1 Journal Article in MOLECULAR HUMAN REPRODUCTION

Unravelling the molecular pathways responsible for sex determination in humans

Jasin TaelmanMina PopovicLaurentijn TillemanMargot Van der JeughtDieter DeforcePetra De SutterFilip Van NieuwerburghBjörn HeindryckxS Chuva De Sousa Lopes

2017

Comprehensive comparison of inner cell mass and trophectoderm reveals the complex nature of chromosomal mosaicism in human embryos

Mina PopovicAnnelies DheedeneCHRISTODOULOS CHRISTODOULOUMargot Van der JeughtFilip Van NieuwerburghDieter DeforcePetra De SutterEtienne Van den AbbeelBjörn MentenBjörn Heindryckx

Direct comparison of distinct naive pluripotent states in human embryonic stem cells

Sharat WarrierMargot Van der JeughtGalbha DuggalLaurentijn TillemanElla SutherlandJasin TaelmanMina PopovicSylvie LiermanSusana Marina Chuva de Sousa LopesAnn Van Soom et al.

A1 Journal Article in NATURE COMMUNICATIONS

Metabolic plasticity complements the unique nature and demands of distinct pluripotency states

Mina PopovicBjörn Heindryckx

Origins of human embryonic stem cell fate : role of the post inner cell mass intermediate

Sharat WarrierMina PopovicJasin TaelmanLaurentijn TillemanSylvie LiermanMinerva Ferrer BuitragoS. Chuva De Sousa LopesAnn Van SoomLuc PeelmanFilip Van Nieuwerburgh et al.

Wnt inhibition during hESC culture provides an improved pluripotent state starting point for directed differentiation

Jasin TaelmanLaurentijn TillemanFilip Van NieuwerburghSharat WarrierMina PopovicMargot Van der JeughtDieter DeforcePetra De SutterBjörn HeindryckxSusana Marina Chuva de Sousa Lopes

2016

Establishment and characterization of naïve pluripotency in human embryonic stem cells

Sharat WarrierMina PopovicMargot Van der JeughtBjörn Heindryckx

Bookchapter in Stem cell heterogeneity : methods and protocols

Massive parallel sequencing uncovers chromosomal mosaicism in human embryonic stem cells in both primed and naive culture conditions

Mina PopovicMargot Van der JeughtFranki SpelemanFilip Van NieuwerburghPetra De SutterBjörn MentenBjörn Heindryckx