Research Explorer

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Researcher

Mieke Carlier

Awards & Distinctions

38 Results

2019

Persistence of piperacillin concentrations after treatment discontinuation : in cauda venenum?

Jan De WaeleC Van EeckhoutPieterjan VanhaelewynMieke CarlierAlain VerstraeteVeronique Stove

A1 Journal Article in INTENSIVE CARE MEDICINE

2018

Development and validation of an LC tandem MS assay for the quantification of β-lactam antibiotics in the sputum of cystic fibrosis patients

Katrien ForierVirginie Van HeckMieke CarlierEva Van BraeckelSabine Van daeleFrans De BaetsPetra SchelstraeteFilomeen HaerynckVeronique StoveLeen Van Simaey et al.

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Population pharmacokinetics of continuous infusion of piperacillin in critically ill patients

Sofie DhaeseJason A RobertsMieke CarlierAlain VerstraeteVeronique StoveJan De Waele

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Proficiency testing for meropenem and piperacillin therapeutic drug monitoring : preliminary results from the Belgian Society on Infectiology and Clinical Microbiology Pharmacokinetic-Pharmacodynamic working group

Mieke CarlierAlexandre AthanasopoulosDaniëlle BorreyPieter ColinFrédéric CottonRaphael DenoozHugo NeelsIsabel SprietTimothy GhysAlain Verstraete et al.

A1 Journal Article in THERAPEUTIC DRUG MONITORING

Quantitation of antibiotics in exhaled breath : a pilot study (ANTIBEX-trial)

Jan HerregodtsEVAN DESCHUYTENEERMieke CarlierAlain VerstraeteVeronique StoveJan De Waele

Subtherapeutic antimicrobial plasma concentrations with standard amoxicillin-clavulanate dosing regimens in paediatric cardiac surgery patients

Evelyn DhontJef WillemsWim VandenbergheMieke CarlierAlain VerstraeteJohan Vande WallePeter De PaepePieter De Cock

2017

Dose optimization of piperacillin/tazobactam in critically ill children

Pieter De CockSven C van DijkmanANNIK DE JAEGERJef WillemsMieke CarlierAlain VerstraeteJoris DelangheHugo RobaysJohan Vande WalleOscar E Della Pasqua et al.

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Dosing of antibiotics in exhaled breath : a pilot study (ANTIBEX-trial)

EVAN DESCHUYTENEERJan HerregodtsSigrid DeprezMieke CarlierAlain VerstraeteJan De Waele

Population pharmacokinetics of continuous infusion piperacillin in critically ill patients

Sofie DhaeseJason A RobertsMieke CarlierAlain VerstraeteVeronique StoveJan De Waele

Stability of amoxicillin and amoxicillin/clavulanic acid reconstituted in isotonic saline

Mieke CarlierAlain VerstraeteJan De WaeleVeronique Stove

A1 Journal Article in JOURNAL OF CHEMOTHERAPY

2016

Piperacollin-tazobactam pharmacokinetis- pharmacodynamics implies a need for higher dosing in critically ill children

Pieter De CockSven Van DijckmanAnnick De JaegerJef WillemsMieke CarlierAlain VerstraeteJoris DelangheHugo RobaysJohan Vande WalleOscar Della Pasqua et al.

2015

A simulation study reveals lack of pharmacokinetic/pharmacodynamic target attainment in de-escalated antibiotic therapy in critically ill patients

Mieke CarlierJason A RobertsVeronique StoveAlain VerstraeteJeffrey LipmanJan De Waele

A1 Journal Article in ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Assays for therapeutic drug monitoring of β-lactam antibiotics: a structured review

Mieke CarlierVeronique StoveSteven C WallisJan De WaeleAlain VerstraeteJeffrey LipmanJason A Roberts

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Augmented renal clearance implies a need for increased amoxicillin-clavulanic acid dosing in critically ill children

Pieter De CockJoseph F StandingCharlotte IS BarkerANNIK DE JAEGEREVELYN DHONTMieke CarlierAlain VerstraeteJoris DelangheHugo RobaysPeter De Paepe

A1 Journal Article in ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Comparison of different equations to assess glomerular filtration in critically ill patients

Mieke CarlierAlexander DumoulinAlexander JanssenSven PicavetSteve VanthuyneRia Van EyndeRaymond VanholderJoris DelangheGert De SchoenmakereJan De Waele et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

Exploration of the pre-analytical stability of β-lactam antibiotics in plasma and blood: implications for therapeutic drug monitoring and pharmacokinetic studies

Mieke CarlierJan De WaeleAlain VerstraeteVeronique Stove

A1 Journal Article in CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Measuring unbound versus total vancomycin concentrations in serum and plasma: methodological issues and relevance

Veronique StoveLouise CoeneMieke CarlierJan De WaeleTOM FIERSAlain Verstraete

A1 Journal Article in THERAPEUTIC DRUG MONITORING

Patient tailored antibiotic therapy in critically ill patients

Mieke CarlierJan De WaeleVeronique Stove

Population pharmacokinetics and dosing simulations of cefepime in septic shock patients receiving continuous renal replacement therapy

Mieke CarlierFabio S TacconeMajorie BeumierLucie SeylerFrédéric CottonFrédérique JacobsJason A Roberts

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Stability of generic brands of meropenem reconstituted in isotonic saline

Mieke CarlierVeronique StoveAlain VerstraeteJan De Waele

A1 Journal Article in MINERVA ANESTESIOLOGICA

Subtleties in practical application of prolonged infusion of β-lactam antibiotics

Jan De WaeleJeffrey LipmanMieke CarlierJason A Roberts

Editorial material

Ultrafast quantification of β-lactam antibiotics in human plasma using UPLC-MS/MS

Mieke CarlierVeronique StoveJan De WaeleAlain Verstraete

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

2014

An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units

Gloria WongAlexander BrinkmanRussell J BenefieldMieke CarlierJan De WaeleNajoua El HelaliOtto FreyStephan HarbarthAngela HuttnerBrett McWhinney et al.

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Beta-lactam antibiotic dosing during continuous renal replacement therapy: how can we optimize therapy?

Jan De WaeleMieke Carlier

Editorial material

Does consistent piperacillin dosing result in consistent therapeutic concentrations in critically ill patients?: a longitudinal study over an entire antibiotic course

Mieke CarlierSofie CarretteVeronique StoveAlain VerstraeteJan De Waele

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Extended versus bolus infusion of meropenem and piperacillin: a pharmacokinetic analysis

Jan De WaeleMieke CarlierEric HostePieter DepuydtJohan DecruyenaereSteven C WallisJeffrey LipmanJason A Roberts

A1 Journal Article in MINERVA ANESTESIOLOGICA

Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures

Mieke CarlierMICHAEL NOEJason A RobertsVeronique StoveAlain VerstraeteJeffrey LipmanJan De Waele

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Protein binding of vancomycin: the impact of temperature on free plasma concentrations

Veronique StoveLouise CoeneMieke CarlierJan De WaeleAlain Verstraete

Therapeutic drug monitoring-based dose optimisation of piperacillin and meropenem: a randomised controlled trial

Jan De WaeleSofie CarretteMieke CarlierVeronique StoveJerina BoelensGeert ClaeysIsabel Leroux-RoelsEric HostePieter DepuydtJohan Decruyenaere et al.

A1 Journal Article in INTENSIVE CARE MEDICINE

2013

Identifying patients at risk for augmented renal clearance in the ICU : limitations and challenges

Mieke CarlierJan De Waele

Editorial material

Meropenem and piperacillin/tazobactam prescribing in critically ill patients : does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended infusions are used?

Mieke CarlierSofie CarretteJason A RobertsVeronique StoveAlain VerstraeteEric HosteJohan DecruyenaerePieter DepuydtJeffrey LipmanSteven C Wallis et al.

A1 Journal Article in CRITICAL CARE

Optimizing β-lactam antibiotic therapy in the critically ill : moving towards patient-tailored antibiotic therapy

Mieke CarlierVeronique StoveJan De Waele

Bookchapter in Annual update in intensive care and emergency medicine 2013

Population pharmacokinetics and dosing simulations of amoxicillin/clavulanic acid in critically ill patients

Mieke CarlierMICHAEL NOEJan De WaeleVeronique StoveAlain VerstraeteJeffrey LipmanJason A Roberts

A1 Journal Article in JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

2012

Quantification of seven β-lactam antibiotics and two β-lactamase inhibitors in human plasma using a validated UPLC-MS/MS method

Mieke CarlierVeronique StoveJason A RobertsERIC VAN DE VELDEJan De WaeleAlain Verstraete

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

TDM based dose optimization of piperacillin and meropenem: a randomized controlled trial

Jan De WaeleSofie CarretteMieke CarlierVeronique StoveEric HostePieter DepuydtJohan DecruyenaereAlain Verstraete

2011

A UPLC-MS/MS assay for the quantification of meropenem and piperacillin concentrations in human plasma

Veronique StoveERIC VAN DE VELDEMieke CarlierAlain Verstraete

Human salivary cortisol, part I : development and full validation of an LC-MS/MS based method

Mieke CarlierKathleen DeiterenJan Van BocxlaerKathleen Croes

Human salivary cortisol, part II: evaluation of an electrochemiluminescence immunoassay (Roche)

Kathleen DeiterenMieke CarlierNico CallewaertM VandermarliereKathleen Croes