Research Explorer

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Researcher

Michaël Kalai

Awards & Distinctions

21 Results

2007

The caspase-generated fragments of PKR cooperate to activate full-length PKR and inhibit translation

Michaël KalaiV SUINNele FestjensAnn MeeusA BERNISXM WANGXavier SaelensPeter Vandenabeele

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

2006

Butylated hydroxyanisole is more than a reactive oxygen species scavenger

Nele FestjensMichaël KalaiJoél SmetAnn MeeusRudy Van CosterXavier SaelensPeter Vandenabeele

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

Necrosis is associated with IL-6 production but apoptosis is not

Tom Vanden BergheMichaël KalaiGeertrui DeneckerAnn MeeusXavier SaelensPeter Vandenabeele

A1 Journal Article in CELLULAR SIGNALLING

2005

A novel caspase-2 complex containing TRAF2 and RIP1

Mohamed LamkanfiKathleen D'HondtLieselotte Vande WalleMarjan Van GurpGeertrui DeneckerJill DemeulemeesterMichaël KalaiWim DeclercqXavier SaelensPeter Vandenabeele

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Apoptotic pathways and their regulation

Greet BrouckaertMichaël KalaiXavier SaelensPeter Vandenabeele

Bookchapter in Apoptotic pathways as targets for novel therapies in cancer and other diseases

Fas induced necrosis.

Tom Vanden BergheNele FestjensMichaël KalaiXavier SaelensPeter Vandenabeele

Bookchapter in Fas Signaling

Protein synthesis persists during necrotic cell death

Xavier SaelensNele FestjensEef ParthoensIsabel VanoverbergheMichaël KalaiF VAN KUPPEVELDPeter Vandenabeele

A1 Journal Article in JOURNAL OF CELL BIOLOGY

2004

Caspase-1 activates nuclear factor of the kappa-enhancer in B cells independently of its enzymatic activity

Mohamed LamkanfiMichaël KalaiXavier SaelensWim DeclercqPeter Vandenabeele

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-12: an overview

Mohamed LamkanfiMichaël KalaiPeter Vandenabeele

Editorial material

Differential signaling to apoptotic and necrotic cell death by Fas-associated death domain protein FADD

Tom Vanden BergheGeert van LooXavier SaelensMarjan Van GurpGreet BrouckaertMichaël KalaiWim DeclercqPeter Vandenabeele

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1 beta generation

Mohamed LamkanfiGeertrui DeneckerMichaël KalaiKathleen D'HondtAnn MeeusWim DeclercqXavier SaelensPeter Vandenabeele

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Phagocytosis of necrotic cells by macrophages is phosphatidylserine dependent and does not induce inflammatory cytokine production

Greet BrouckaertMichaël KalaiDmitri KryskoXavier SaelensDominique VercammenMatladi NdlovuGuy HaegemanKatharina D'HerdePeter Vandenabeele

A1 Journal Article in MOLECULAR BIOLOGY OF THE CELL

2003

Caspase-1 and caspase-8 cleave and inactivate cellular parkin

S KAHNSMichaël KalaiLD JAKOBSENBFC CLARKPeter VandenabeelePH JENSEN

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis

Tom Vanden BergheMichaël KalaiGeert van LooWim DeclercqPeter Vandenabeele

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of internalization of apoptotic and necrotic L929 cells by a macrophage cell line studied by electron microscopy

Dmitri KryskoGreet BrouckaertMichaël KalaiPeter VandenabeeleKatharina D'Herde

A1 Journal Article in JOURNAL OF MORPHOLOGY

Regulation of the expression and processing of caspase-12

Michaël KalaiMohamed LamkanfiGeertrui DeneckerM BoogmansSaskia LippensAnn MeeusWim DeclercqPeter Vandenabeele

A1 Journal Article in JOURNAL OF CELL BIOLOGY

The caspase family

Mohamed LamkanfiWim DeclercqBart DepuydtMichaël KalaiXavier SaelensPeter Vandenabeele

Bookchapter in Caspases-Their Role in Cell Death and Cell Survival

2002

Alice in caspase land. A phylogenetic analysis of caspases from worm to man.

Mohamed LamkanfiWim DeclercqMichaël KalaiXavier SaelensPeter Vandenabeele

Editorial material

Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA

Michaël KalaiGeert van LooTom Vanden BergheAnn MeeusWilhelmina BurmXavier SaelensPeter Vandenabeele

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

2001

Translation inhibition in apoptosis - Caspase-dependent PKR activation and eIF2-alpha phosphorylation.

Xavier SaelensMichaël KalaiPeter Vandenabeele

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

1999

Dimerization of the interferon type I receptor IFNaR2-2 is sufficient for induction of interferon effector genes but not for full antiviral activity.

E PATTYNX VAN OSTADEL SCHAUVLIEGEA VERHEEMichaël KalaiJoël VandekerckhoveJan Tavernier

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY