Research Explorer

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Researcher

Matthijs Vynck

Awards & Distinctions

37 Results

2024

Benchmarking digital PCR partition classification methods with empirical and simulated duplex data

Yao ChenWard De SpiegelaereWim TrypsteenDavid GleerupJo VandesompeleAntoon LievensMatthijs VynckOlivier Thas

U Journal Article in BRIEFINGS IN BIOINFORMATICS

2023

Bias reduction improves accuracy and informativity of high-throughput sequencing chimerism assays

Matthijs VynckFriedel NolletLode SibbensHelena Devos

A1 Journal Article in CLINICA CHIMICA ACTA

Comparative assessment of survival and clinical outcome between two commercial vitrification kits with different warming protocols after blastocyst culture : potential perspectives toward simplified warming procedures

Jan GunstMatthijs VynckKatleen HostensValerie StandaertSylvie RoggemanArne van de Vijver

A1 Journal Article in REPRODUCTIVE SCIENCES

Digital PCR partition classification

Matthijs VynckYao ChenDavid GleerupJo VandesompeleWim TrypsteenAntoon LievensOlivier ThasWard De Spiegelaere

A1 Journal Article in CLINICAL CHEMISTRY

2022

Chimerism monitoring using biallelic single nucleotide or insertion/deletion polymorphisms : how many markers to screen?

Matthijs VynckFriedel NolletLode SibbensHelena Devos

A1 Journal Article in CLINICA CHIMICA ACTA

Some key considerations regarding the design and evaluation of high-throughput sequencing-based biallelic chimerism assays

A1 Journal Article in INTERNATIONAL JOURNAL OF HEMATOLOGY

2021

Dynamics of the cellular and humoral immune response after BNT162b2 mRNA Covid-19 vaccination in Covid-19 naive nursing home residents

Jens Van PraetStefaan VandecasteeleAnneleen De RooMatthijs VynckAn De VrieseMarijke Reynders

A1 Journal Article in JOURNAL OF INFECTIOUS DISEASES

Performance assessment of the Devyser high-throughput sequencing-based assay for chimerism monitoring in patients after allogeneic hematopoietic stem cell transplantation

Matthijs VynckFriedel NolletLode SibbensBernadette LievensAstrid DenysBarbara CauwelierHelena Devos

A1 Journal Article in JOURNAL OF MOLECULAR DIAGNOSTICS

2020

Malignant progression of donor-engrafted clonal hematopoiesis in sibling recipients after stem cell transplantation

Louis NevejanFriedel NolletHelena DevosMatthijs VynckPieter Van VlierbergheMercedeh TajdarTom LodewyckDominik Selleslag

Editorial material

2019

Power Doppler ultrasound and contrast-enhanced ultrasound demonstrate non-invasive tumour vascular response to anti-vascular therapy in canine cancer patients

Eline AbmaEmmelie StockWard De SpiegelaereLeen Van BrantegemKatrien VanderperrenYicheng NiMatthijs VynckSylvie DaminetKaat De ClercqHilde De Rooster

A1 Journal Article in SCIENTIFIC REPORTS

2018

A single dose of intravenous combretastatin A4-phosphate is reasonably well tolerated and significantly reduces tumour vascularization in canine spontaneous cancers

Eline AbmaWard De SpiegelaereKatrien VanderperrenEmmelie StockLeen Van BrantegemIne CornelisSylvie DaminetY NiMatthijs VynckGlenn Verstraete et al.

A1 Journal Article in VETERINARY AND COMPARATIVE ONCOLOGY

Data analysis methods for digital PCR quantification

Matthijs VynckOlivier ThasJo Vandesompele

On determining the power of digital PCR experiments

Matthijs VynckJo VandesompeleOlivier Thas

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Prognostic and therapeutic implications of circulating androgen receptor gene copy number in prostate cancer patients using droplet digital polymerase chain reaction

Sarah BuelensTom ClaeysBert DhondtFilip PoelaertMatthijs VynckNurten YigitOlivier ThasPiet OstJo VandesompeleNicolaas Lumen et al.

A1 Journal Article in CLINICAL GENITOURINARY CANCER

Reducing bias in digital PCR experiments by appropriate modelling of volume variability

Matthijs VynckOlivier Thas

Reducing bias in digital PCR quantification experiments : the importance of appropriate modelling of volume variability

Matthijs VynckOlivier Thas

A1 Journal Article in ANALYTICAL CHEMISTRY

2017

A digital PCR data analysis workflow : from sample to effective result

Matthijs VynckOlivier Thas

A unified censored normal regression model for qPCR differential gene expression analysis

Peter PipelersLieven ClementMatthijs VynckJan HellemansJo VandesompeleOlivier Thas

A1 Journal Article in PLOS ONE

Androgen receptor gene copy number detection using droplet digital PCR and its therapeutic consequences in prostate cancer patients

Sarah BuelensTom ClaeysCandy KumpsBert DhondtFilip PoelaertNurten YigitMatthijs VynckOlivier ThasPiet OstJo Vandesompele et al.

Breath analysis by gas chromatography-mass spectrometry and electronic nose to screen for pleural mesothelioma : a cross-sectional case-control study

Kevin LamotePaul BrinkmanLore VandermeerschMatthijs VynckPeter J SterkHerman Van LangenhoveOlivier ThasJoris Van CleemputKristiaan NackaertsJan Van Meerbeeck

A1 Journal Article in ONCOTARGET

Exhaled breath analysis allows exclusive screening for malignant pleural mesothelioma

Kevin LamoteMatthijs VynckOlivier ThasJoris Van CleemputKristiaan NackaertsJan Van Meerbeeck

Exhaled breath to screen for malignant pleural mesothelioma : a validation study

Kevin LamoteMatthijs VynckOlivier ThasJoris Van CleemputKristiaan NackaertsJan Van Meerbeeck

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Quality control of digital PCR assays and platforms

Matthijs VynckJo VandesompeleOlivier Thas

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

The occurrence and therapeutic consequences of androgen receptor copy number gain in prostate cancer patients using Droplet Digital PCR

Sarah BuelensTom ClaeysCandy KumpsBert DhondtFilip PoelaertY NurtenMatthijs VynckOlivier ThasPiet OstJo Vandesompele et al.

2016

Detection of malignant pleural mesothelioma in exhaled breath by multicapillary column/ion mobility spectrometry (MCC/IMS)

Kevin LamoteMatthijs VynckJoris Van CleemputOlivier ThasKristiaan NackaertsJan Van Meerbeeck

A1 Journal Article in JOURNAL OF BREATH RESEARCH

Flexible analysis of digital PCR experiments using generalized linear mixed models

Matthijs VynckJo VandesompeleNele NijsBjörn MentenAriane De GanckOlivier Thas

A2 Journal Article in BIOMOLECULAR DETECTION AND QUANTIFICATION

The future of digital polymerase chain reaction in virology

Matthijs VynckWim TrypsteenOlivier ThasLinos VandekerckhoveWard De Spiegelaere

A1 Journal Article in MOLECULAR DIAGNOSIS & THERAPY

Threshold setting in duplex digital PCR experiments

Matthijs VynckOlivier Thas

2015

Breath analysis by ion mobility spectrometry allows discrimination of pleural mesothelioma patients from controls

Kevin LamoteMatthijs VynckJoris Van CleemputOlivier ThasKristiaan NackaertsJan Van Meerbeeck

Data analysis of droplet digital PCR with generalized linear mixed models

Olivier ThasMatthijs VynckJo Vandesompele

Extreme value theory for threshold determination in droplet digital PCR experiments

Matthijs VynckWim TrypsteenJan De NevePawel BonczkowskiMaja KiselinovaEva MalatinkováKAREN VERVISCHOlivier ThasLinos VandekerckhoveWard De Spiegelaere

GLMMs for nucleic acid concentration estimation in digital droplet PCR

Matthijs VynckJo VandesompeleOlivier Thas

Improving accuracy and precision of dPCR experiments by relying on multiple reference genes

Matthijs VynckJo VandesompeleOlivier Thas

Threshold determination in droplet digital PCR experiments using extreme value theory

Matthijs VynckWim TrypsteenJan De NevePawel BonczkowskiMaja KiselinovaEva MalatinkováKAREN VERVISCHOlivier ThasLinos VandekerckhoveWard De Spiegelaere

Volatile organic compounds increase the likelihood of detecting malignant pleural mesothelioma

Kevin LamoteMatthijs VynckJoris Van CleemputOlivier ThasKristiaan NackaertsJan Van Meerbeeck

ddcRquant: threshold determination for single channel droplet digital PCR experiments

Wim TrypsteenMatthijs VynckJan De NevePawel BonczkowskiMaja KiselinovaEva MalatinkováKAREN VERVISCHOlivier ThasLinos VandekerckhoveWard De Spiegelaere

ddpcRquant: threshold determination for single channel droplet digital PCR experiments

Wim TrypsteenMatthijs VynckJan De NevePawel BonczkowskiMaja KiselinovaEva MalatinkováKAREN VERVISCHOlivier ThasLinos VandekerckhoveWard De Spiegelaere

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY