Research Explorer

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Researcher

Matthias Trappeniers

Awards & Distinctions

10 Results

2011

6''-Modified alpha-GalCer analogs capable of establishing an extra interaction with Cd1d leading to a polarized Th1 response and superior tumor protection

Serge Van CalenberghNora PauwelsSANDRINE ASPESLAGHYaLi LiMatthias TrappeniersDirk ZajoncDirk Elewaut

Galactose modified iNKT cell agonists stabilised by a novel structural modification of CD1D lead to marked TH1 polarisation in vivo

SANDRINE ASPESLAGHYaLi LiEsther Dawen YuNora PauwelsMatthias TrappeniersEnrico GirardiTine DecruyKatrien Van BenedenKoen VenkenMichael Drennan et al.

Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis

SANDRINE ASPESLAGHYali LiEsther Dawen YuNora PauwelsMatthias TrappeniersEnrico GirardTine DecruyKatrien Van BenedenKoen VenkenMichael Drennan et al.

A1 Journal Article in EMBO JOURNAL

2010

Optimizing the iNKT cell dependent antitumor effect using an altered glycolipid

SANDRINE ASPESLAGHYali LiTine DecruyKatrien Van BenedenKoen VenkenMatthias TrappeniersSerge Van CalenberghDirk ZajoncDirk Elewaut

Optimizing the iNKT cell dependent antitumor effect using an altered glycolipid

SANDRINE ASPESLAGHYali LiTine DecruyKatrien Van BenedenMichael DrennanKoen VenkenMatthias TrappeniersSerge Van CalenberghDirk ZajoncDirk Elewaut

Synthesis and evaluation of amino-modified α-GalCer analogues

Matthias TrappeniersRené ChoforSANDRINE ASPESLAGHYali LiBruno LinclauDirk M ZajoncDirk ElewautSerge Van Calenbergh

A1 Journal Article in ORGANIC LETTERS

Synthesis of sphingosine- and sugar modified α-GalCer analogues : towards new immunomodulatory agents

Matthias TrappeniersSerge Van Calenbergh

2009

The synthesis and in vivo evaluation of 2',2'-difluoro KRN7000

Leo LeungCyrille TomassiKatrien Van BenedenTine DecruyMatthias TrappeniersDirk ElewautYifang GaoTim ElliottAymen Al-ShamkhaniChristian Ottensmeier et al.

A1 Journal Article in CHEMMEDCHEM

2008

6'-Derivatised α-GalCer analogues capable of inducing strong CD1d-mediated Th1-biased NKT cell responses in mice

Matthias TrappeniersKatrien Van BenedenTine DecruyBruno LinclauDirk ElewautSerge Van Calenbergh

A1 Journal Article in JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and in vitro evaluation of α-GalCer epimers

Matthias TrappeniersStijn GoormansKatrien Van BenedenTine DecruyBruno LinclauAymen Al-ShamkhaniTim ElliottChristian OttensmeierJoern M. WernerDirk Elewaut et al.

A1 Journal Article in CHEMMEDCHEM