Research Explorer

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Researcher

Mathieu Sprengers

Publications & Research Data

Awards & Distinctions

40 Results

2025

Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses

Sielke CaesteckerEmma LescrauwaetKristl VonckMathieu SprengersEvelien CarrettePaul BoonLars Emil LarsenRobrecht Raedt

A1 Journal Article in FRONTIERS IN NEUROSCIENCE

Investigating the working mechanism of transcranial direct current stimulation

Emma LescrauwaetMathieu SprengersEvelien CarretteChloé AlgoetAnn MertensDeborah KloosterSteven BeumerRob MestromRobrecht RaedtPaul Boon et al.

A1 Journal Article in NEUROMODULATION

Photopharmacological activation of adenosine A1 receptor signaling suppresses seizures in a mouse model for temporal lobe epilepsy

Jeroen SpanogheEvelien WynendaeleMarijke VergaelenMaren De ColvenaerTina MarimanKristl VonckEvelien CarretteWytse WadmanErine CraeyLars Emil Larsen et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Repetitive transcranial magnetic stimulation for refractory and super-refractory status epilepticus : a systematic review

Chloé AlgoetKato Van RooyPaul BoonEvelien CarretteSofie CarretteMathieu SprengersRobrecht RaedtAnn MertensAlfred MeursKristl Vonck

A1 Journal Article in NEUROMODULATION

The Effectiveness of Cenobamate in Patients Treated With Vagus Nerve Stimulation for Drug Resistant Epilepsy

Lara HogeveenBenjamin LegrosAlfred MeursVeerle De HerdtMathieu SprengersStephanie HödlAnn MertensStefanie GadeyneRobrecht RaedtFrank Dewaele et al.

U Journal Article in European Journal of Neurology

2024

Increased dentate gyrus excitability in the intrahippocampal kainic acid mouse model for temporal lobe epilepsy

Marijke VergaelenSimona ManzellaKristl VonckErine CraeyJeroen SpanogheMathieu SprengersEvelien CarretteWytse Jan WadmanJean DelbekePaul Boon et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The effectiveness of Cenobamate in patients previously treated with Vagus Nerve Stimulation for drug resistant epilepsy

Lara HogeveenBenjamin LegrosAlfred MeursVeerle De HerdtMathieu SprengersStephanie HödlAnn MertensStefanie GadeyneRobrecht RaedtFrank Dewaele et al.

2023

Assessing the effects of burr holes in transcranial direct current simulation

Steven BeumerMaarten PaulidesAlbert ColonRaymond van EeEvelien CarretteEmma LescrauwaetDeborah KloosterMathieu SprengersPaul BoonRob Mestrom

Deep brain stimulation of the anterior nucleus of the thalamus in drug resistant epilepsy in the MORE multicenter patient registry

J PeltolaAJ ColonJ PimentelVA CoenenA Gil-NagelAG FerreiraK LehtimäkiP RyvlinRS TaylorL Ackermans et al.

A1 Journal Article in NEUROLOGY

Investigating the mechanism of action of tDCS by means of TMS-EMG

Emma LescrauwaetMathieu SprengersEvelien CarretteDeborah KloosterSteven BeumerRob MestromKristl VonckPaul Boon

2022

Cathodal transcranial direct current stimulation : impact of the ring radius of a 4x1-ring electrode configuration

Mathieu SprengersEvelien CarretteEmma LescrauwaetSteven BeumerKristl VonckRob MestromPaul Boon

Ex vivo feedback control of neurotransmission using a photocaged adenosine A1 receptor agonist

Erine CraeyFabian HulpiaJeroen SpanogheSimona ManzellaLars Emil LarsenMathieu SprengersDimitri De BundelIlse SmoldersEvelien CarretteJean Delbeke et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Recent advances in the use of focused ultrasound as a treatment for epilepsy

Emma LescrauwaetKristl VonckMathieu SprengersRobrecht RaedtDeborah KloosterEvelien CarrettePaul Boon

A1 Journal Article in FRONTIERS IN NEUROSCIENCE

2021

Long‐term chemogenetic suppression of seizures in a multifocal rat model of temporal lobe epilepsy

Marie-Gabrielle GoossensPaul BoonWytse WadmanChris Van den HauteVeerle BaekelandtAlain VerstraeteKristl VonckLars Emil LarsenMathieu SprengersEvelien Carrette et al.

A1 Journal Article in EPILEPSIA

Seizures and interictal epileptiform activity in the rat collagenase model for intracerebral hemorrhage

Charlotte GermonpréSilke ProesmansCharlotte BouckaertMathieu SprengersPaul BoonRobrecht RaedtVeerle De Herdt

A1 Journal Article in FRONTIERS IN NEUROSCIENCE

2020

Acute symptomatic seizures following intracerebral hemorrhage in the rat collagenase model

Charlotte GermonpréSilke ProesmansCharlotte BouckaertLatoya StevensMathieu SprengersKristl VonckEvelien CarretteWytse WadmanPaul BoonRobrecht Raedt et al.

A1 Journal Article in EPILEPSY RESEARCH

Deep brain stimulation for drug-resistant epilepsy : efficacy and mechanism of action

Mathieu SprengersKristl VonckPaul Boon

Deep brain stimulation reduces evoked potentials with a dual time course in freely moving rats : potential neurophysiological basis for intermittent as an alternative to continuous stimulation

Mathieu SprengersRobrecht RaedtLars Emil LarsenJean DelbekeWytse WadmanPaul BoonKristl Vonck

A1 Journal Article in EPILEPSIA

Identification of vagus nerve stimulation parameters affecting rat hippocampal electrophysiology without temperature effects

Wouter Van LysebettensKristl VonckLars Emil LarsenLatoya StevensCharlotte BouckaertCharlotte GermonpréMathieu SprengersEvelien CarretteJean DelbekeWytse Wadman et al.

A1 Journal Article in BRAIN STIMULATION

2019

Biotinidase deficiency: A treatable cause of opticospinal syndrome in young adults

Vincent Van IseghemMathieu SprengersJulie De ZaeytijdSindic CJMB WillekensBart DermautDimitri HemelsoetGuy Laureys

Editorial material

EBV-NMDA double positive encephalitis in an immunocompromised patient

Jinte GarréMathieu SprengersD Van MelkebekeGuy Laureys

A1 Journal Article in JOURNAL OF THE NEUROLOGICAL SCIENCES

Hypothermia masks most of the effects of rapid cycling VNS on rat hippocampal electrophysiology

Wouter Van LysebettensKristl VonckLars Emil LarsenMathieu SprengersEvelien CarretteCharlotte BouckaertJean DelbekeWytse WadmanPaul BoonRobrecht Raedt

A1 Journal Article in INTERNATIONAL JOURNAL OF NEURAL SYSTEMS

2018

Vagus nerve stimulation induced hypothermia drives most of the effects on hippocampal electrophysiology in rats

Wouter Van LysebettensKristl VonckLars Emil LarsenMathieu SprengersEvelien CarretteJean DelbekeWytse WadmanPaul BoonRobrecht Raedt

Vagus nerve stimulation induced hypothermia drives most of the effects on hippocampal electrophysiology in rats

Wouter Van LysebettensKristl VonckLars Emil LarsenMathieu SprengersEvelien CarretteJean DelbekeWytse WadmanPaul BoonRobrecht Raedt

2017

Clinical vagus nerve stimulation paradigms induce pronounced brain and body hypothermia in rats

Lars Emil LarsenWouter Van LysebettensCharlotte GermonpréSofie CarretteSofie DaelemansMathieu SprengersLisa ThyrionWytse Jan WadmanEvelien CarretteJean Delbeke et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF NEURAL SYSTEMS

Deep brain and cortical stimulation for epilepsy

Mathieu SprengersKristl VonckEvelien CarretteAnthony G MarsonPaul Boon

A1 Journal Article in COCHRANE DATABASE OF SYSTEMATIC REVIEWS

Evolution of sleep abnormalities in a patient with anti-Lgi1 antibody associated autoimmune encephalitis

Tim KeldermanMathieu SprengersPaul BoonStephanie HödlAlfred Meurs

Involvement of fast-spiking cells in ictal sequences during spontaneous seizures in rats with chronic temporal lobe epilepsy

Adam R NeumannRobrecht RaedtHendrik W SteenlandMathieu SprengersKatarzyna BzymekZaneta NavratilovaLilia MesinaJeanne XieValerie LapointeFabian Kloosterman et al.

A1 Journal Article in BRAIN

2016

Disruption, but not overexpression of urate oxidase alters susceptibility to pentylenetetrazole- and pilocarpine-induced seizures in mice

Lisa ThyrionJeanelle PortelliRobrecht RaedtGriet GlorieuxLars Emil LarsenMathieu SprengersWouter Van LysebettensEvelien CarretteJean DelbekeKristl Vonck et al.

A1 Journal Article in EPILEPSIA

Vagus nerve stimulation applied with a rapid cycle has more profound influence on hippocampal electrophysiology than a standard cycle

Lars Emil LarsenWytse WadmanDaniele MarinazzoPieter van MierloJean DelbekeSofie DaelemansMathieu SprengersLisa ThyrionWouter Van LysebettensEvelien Carrette et al.

A1 Journal Article in NEUROTHERAPEUTICS

2015

Responsive neurostimulation in epilepsy

Sofie CarrettePaul BoonMathieu SprengersRobrecht RaedtKristl Vonck

A1 Journal Article in EXPERT REVIEW OF NEUROTHERAPEUTICS

The systemic kainic acid rat model of temporal lobe epilepsy: long-term EEG monitoring

Bregt Van NieuwenhuyseRobrecht RaedtMathieu SprengersIne DauweStefanie GadeyneEvelien CarretteJean DelbekeWytse WadmanPaul BoonKristl Vonck

A1 Journal Article in BRAIN RESEARCH

2014

Deep brain and cortical stimulation for epilepsy

Mathieu SprengersKristl VonckEvelien CarretteAnthony G MarsonPaul Boon

A1 Journal Article in COCHRANE DATABASE OF SYSTEMATIC REVIEWS

2013

A decade of experience with deep brain stimulation for patients with refractory medial temporal lobe epilepsy

Kristl VonckMathieu SprengersEvelien CarretteMarijke MiattonAlfred MeursVeerle De HerdtEric AchtenEvert ThieryRobrecht RaedtDirk Van Roost et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF NEURAL SYSTEMS

Invasive brain stimulation in the treatment of epilepsy

Mathieu SprengersRobrecht RaedtAlfred MeursEvelien CarretteDirk Van RoostPaul BoonKristl Vonck

2012

A decade of experience with deep brain stimulation for patients with refractory medial temporal lobe epilepsy

Mathieu SprengersKristl VonckEvelien CarretteAlfred MeursDirk Van RoostPaul Boon

A decade of experience with deep brain stimulation for patients with refractory medial temporal lobe epilepsy

Mathieu SprengersKristl VonckEvelien CarretteAlfred MeursDirk Van RoostPaul Boon

A decade of experience with deep brain stimulation for patients with refractory medial temporal lobe epilepsy

Mathieu SprengersKristl VonckEvelien CarretteAlfred MeursDirk Van RoostPaul Boon

Hippocampal deep brain stimulation may be an alternative for resective surgery in medically refractory temporal lobe epilepsy

Mathieu SprengersPaul BoonKristl Vonck

Bookchapter in Case studies in epilepsy : common and uncommon presentations

Neurostimulation for epilepsy

Kristl VonckVeerle De HerdtMathieu SprengersEleonor Ben-Menachem

Bookchapter in Epilepsy, part II : treatment