Research Explorer

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Researcher

Mathieu Bertrand

71 Results

2020

A20 and cell death-driven inflammation

Dario PriemGeert van LooMathieu Bertrand

A1 Journal Article in TRENDS IN IMMUNOLOGY

Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation

Lucie LaurienMasahiro NagataHannah SchünkeTom DelangheJanica L. WiedersteinSnehlata KumariRobin SchwarzerTeresa CoronaMarcus KrügerMathieu BertrandVangelis KondylisManolis Pasparakis

A1 Journal Article in NATURE COMMUNICATIONS

Immunodominant AH1 antigen-deficient necroptotic, but not apoptotic, murine cancer cells induce antitumor protection

Tania Love AaesHanne VerschuereAgnieszka KaczmarekLiesbeth HeyndrickxBartosz WiernickiIris DelrueBram De CraeneJoachim TaminauTinneke DelvaeyeMathieu BertrandWim DeclercqGeert BerxDmitri KryskoSandy Adjemian CataniPeter Vandenabeele

A1 Journal Article in JOURNAL OF IMMUNOLOGY

OTULIN prevents liver inflammation and hepatocellular carcinoma by inhibiting FADD- and RIPK1 kinase-mediated hepatocyte apoptosis

Lien VerboomArne MartensDario PriemEsther HosteMozes SzeHanna-Kaisa VikkulaLisette Van HoveSofie VoetJana RoelsJonathan MaelfaitLaura BongiovanniAlain de BruinCharlotte ScottYvan SaeysManolis PasparakisMathieu BertrandGeert van Loo

A1 Journal Article in CELL REPORTS

RIPK1 kinase-dependent death : a symphony of phosphorylation events

Tom DelangheYves DondelingerMathieu Bertrand

A1 Journal Article in TRENDS IN CELL BIOLOGY

Respiratory Syncytial Virus infection promotes necroptosis and HMGB1 release by airway epithelial cells

Jennifer SimpsonZhixuan LohMd Ashik UllahJason P LynchRhiannon B. WerderNatasha CollinsonVivian ZhangYves DondelingerMathieu BertrandMark L. EverardChristopher C BlythGunter HartelAntoon J. Van OosterhoutPeter J GoughJohn BertinJohn W. UphamKirsten M. SpannSimon Phipps

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The ubiquitin-dependent regulation of the inflammatory response by A20 and MAGED1

Dario PriemMathieu Bertrand

Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities

Arne MartensDario PriemEsther HosteJessica VettersSofie RennenLeen CatrysseSofie VoetLaura DeelenMozes SzeHanna-Kaisa VikkulaKarolina SlowickaTino HochepiedKalliopi IliakiAndy WullaertSophie JanssensMohamed LamkanfiRudi BeyaertMarietta ArmakaMathieu BertrandGeert van Loo

A1 Journal Article in NATURE IMMUNOLOGY

2019

A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms

Dario PriemMichael DevosSarah DruwéArne MartensKarolina SlowickaAdrian T TingManolis PasparakisWim DeclercqPeter VandenabeeleGeert van LooMathieu Bertrand

A1 Journal Article in CELL DEATH & DISEASE

Network approach identifies Pacer as an autophagy protein involved in ALS pathogenesis

S. BeltranM. NassifE. VicencioJ. ArcosL. LabradorB. I. CortesC. CortezC. A. BergmannS. EspinozaM. F. HernandezJ. M. MatamalaL. BargstedS. MatusDiego Rojas RiveraMathieu BertrandD. B. MedinasC. HetzP. A. ManqueU. Woehlbier

A1 Journal Article in MOLECULAR NEURODEGENERATION

Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation

Yves DondelingerTom DelangheDario PriemMeghan A Wynosky-DolfiDaniel SorobeteaDiego Rojas RiveraPiero GiansantiRia RoelandtJulia GropengiesserKlaus RuckdeschelSavvas SavvidesAlbert JR HeckPeter VandenabeeleIgor E BrodskyMathieu Bertrand

A1 Journal Article in NATURE COMMUNICATIONS

2018

MK2 puts an additional brake on RIPK1 cytotoxic potential

Yves DondelingerTom DelangheMathieu Bertrand

Editorial material

Molecular mechanisms of cell death : recommendations of the Nomenclature Committee on Cell Death 2018

Lorenzo GalluzziIlio VitaleStuart A AaronsonJohn M AbramsDieter AdamPatrizia AgostinisEmad S AlnemriLucia AltucciIvano AmelioDavid W. AndrewsMargherita Annicchiarico-PetruzzelliAlexey V. AntonovEli AramaEric H. BaehreckeNickolai A. BarlevNicolas G. BazanFrancesca BernassolaMathieu BertrandKatiuscia BianchiMikhail V. BlagosklonnyKlas BlomgrenChristoph BornerPatricia BoyaCatherine BrennerMichelangelo CampanellaEleonora CandiDidac Carmona-GutierrezFrancesco CecconiFrancis K. -M. ChanNavdeep S. ChandelEmily H ChengJerry E ChipukJohn A CidlowskiAaron CiechanoverGerald M CohenMarcus ConradJuan R Cubillos-RuizPeter E CzabotarVincenzo D'AngiolellaTed M DawsonValina L DawsonVincenzo De laurenziRuggero De MariaKlaus-Michael DebatinRalph J DeBerardinisMohanish DeshmukhNicola Di DanieleFrancesco Di VirgilioVishva M DixitScott J DixonColin S DuckettBrian D DynlachtWafik S El-DeiryJohn W ElrodGian Maria FimiaSimone FuldaAna J Garcia-SaezAbhishek D GargCarmen GarridoEvripidis GavathiotisPierre GolsteinEyal GottliebDouglas R GreenLloyd A GreeneHinrich GronemeyerAtan GrossGyorgy HajnoczkyJ Marie HardwickIsaac S HarrisMichael O HengartnerClaudio HetzHidenori IchijoMarja JaattelaBertrand JosephPhilipp J JostPhilippe P JuinWilliam J KaiserMichael KarinThomas KaufmannOliver KeppAdi KimchiRichard N KitsisDaniel J KlionskyRichard A KnightSharad KumarSam W LeeJohn J LemastersBeth LevineAndreas LinkermannStuart A LiptonRichard A LockshinCarlos Lopez-OtinScott W LoweTom LueddeEnrico LugliMarion MacFarlaneFrank MadeoMichal MalewiczWalter MalorniGwenola ManicJean-Christophe MarineSeamus J MartinJean-Claude MartinouJan Paul MedemaPatrick MehlenPascal MeierSonia MelinoEdward A MiaoJeffery D MolkentinUte M MollCristina Munoz-PinedoShigekazu NagataGabriel NunezAndrew OberstMoshe OrenMichael OverholtzerMichele PaganoTheocharis PanaretakisManolis PasparakisJosef M PenningerDavid M PereiraShazib PervaizMarcus E PeterMauro PiacentiniPaolo PintonJochen HM PrehnHamsa PuthalakathGabriel A RabinovichMarkus RehmRosario RizzutoCecilia MP RodriguesDavid C RubinszteinThomas RudelKevin M RyanEmre SayanLuca ScorranoFeng ShaoYufang ShiJohn SilkeHans-Uwe SimonAntonella SistiguBrent R StockwellAndreas StrasserGyorgy SzabadkaiStephen WG TaitDaolin TangNektarios TavernarakisAndrew ThorburnYoshihide TsujimotoBoris TurkTom Vanden BerghePeter VandenabeeleMatthew G Vander HeidenAndreas VillungerHerbert W VirginKaren H VousdenDomagoj VucicErwin F WagnerHenning WalczakDavid WallachYing WangJames A WellsWill WoodJunying YuanZahra ZakeriBoris ZhivotovskyLaurence ZitvogelGerry MelinoGuido Kroemer

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

Monitoring RIPK1 phosphorylation in the TNFR1 signaling complex

Dario PriemYves DondelingerMathieu Bertrand

Bookchapter in Programmed necrosis : methods and protocols

N-glycosylation of mouse TRAIL-R restrains TRAIL-induced apoptosis

Yann EstornesYves DondelingerKathrin WeberInge BruggemanAdam PeallMarion MacFarlaneSerge LebecquePeter VandenabeeleMathieu Bertrand

A1 Journal Article in CELL DEATH & DISEASE

The E3 ubiquitin ligases HOIP and cIAP1 are recruited to the TNFR2 signaling complex and mediate TNFR2-induced canonical NF-κB signaling

Alice BorghiMira HaegmanRoman FischerIsabelle CarpentierMathieu BertrandClaude LibertInna AfoninaRudi Beyaert

A1 Journal Article in BIOCHEMICAL PHARMACOLOGY

Type III collagen affects dermal and vascular collagen fibrillogenesis and tissue integrity in a mutant Col3a1 transgenic mouse model

Sanne D'hondtBrecht GuillemynDelfien SyxSofie SymoensRiet De RyckeLeen VanhoutteWendy ToussaintBart LambrechtAnne De PaepeDouglas R KeeneYoshihiro IshikawaHans Peter BächingerSophie JanssensMathieu BertrandFransiska Malfait

A1 Journal Article in MATRIX BIOLOGY

2017

Experimental African trypanosome infection suppresses the development of multiple myeloma in mice by inducing intrinsic apoptosis of malignant plasma cells

Nathan De BeuleEline MenuMathieu BertrandMérédis FavreauElke De BruyneKen MaesKim De VeirmanMagdalena RadwanskaAfshin SamaliStefan MagezKarin VanderkerkenCarl De Trez

A1 Journal Article in ONCOTARGET

MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death

Yves DondelingerTom DelangheDiego Rojas RiveraDario PriemTinneke DelvaeyeInge BruggemanPeter VandenabeeleMathieu Bertrand

A1 Journal Article in NATURE CELL BIOLOGY

RIPK1 protects hepatocytes from Kupffer cells-mediated TNF-induced apoptosis in mouse models of PAMP-induced hepatitis

Aveline FilliolClaire Piquet-PellorceCéline Raguénès-NicolSarah DionMuhammad FarooqCatherine Lucas-ClercPeter VandenabeeleMathieu BertrandJacques Le SeyecMichel Samson

A1 Journal Article in JOURNAL OF HEPATOLOGY

RIPK1 protects hepatocytes from death in Fas-induced hepatitis

Aveline FilliolMuhammad FarooqClaire Piquet-PellorceValentine GenetMarie-Thérèse Dimanche-BoitrelPeter VandenabeeleMathieu BertrandMichel SamsonJacques Le Seyec

A1 Journal Article in SCIENTIFIC REPORTS

Type III collagen : a major fibrillar collagen with major issues

Sanne D'hondtFransiska MalfaitMathieu BertrandSophie Janssens

Type III collagen is important for type I collagen fibrillogenesis and for dermal and cardiovascular development

Sanne D'hondtBrecht GuillemynSofie SymoensRiet De RyckeYoshi IshikawaHans Peter BachingerSophie JanssensMathieu BertrandFransiska Malfait

When PERK inhibitors turn out to be new potent RIPK1 inhibitors : critical issues on the specificity and use of GSK2606414 and GSK2656157

Diego Rojas RiveraTinneke DelvaeyeRia RoelandtWim NerinckxKoen AugustynsPeter VandenabeeleMathieu Bertrand

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

2016

A real-time fluorometric method for the simultaneous detection of cell death type and rate

Sasker GrootjansBehrouz HassanniaIris DelrueBartosz WiernickiYves DondelingerMathieu BertrandDmitri KryskoMarnik VuylstekePeter VandenabeeleTom Vanden Berghe

A1 Journal Article in NATURE PROTOCOLS

A siRNA screen reveals the prosurvival effect of protein kinase A activation in conditions of unresolved endoplasmic reticulum stress

Miguel AguiletaDiego Rojas RiveraYann EstornesGert Van IsterdaelPeter VandenabeeleMathieu Bertrand

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

An evolutionary perspective on the necroptotic pathway

Yves DondelingerPaco HulpiauYvan SaeysMathieu BertrandPeter Vandenabeele

A1 Journal Article in TRENDS IN CELL BIOLOGY

Characterization of new proteins involved in apoptosis regulation

Miguel AguiletaMathieu BertrandPeter Vandenabeele

Differential expression of type III collagen in male and female mice

Sanne D'hondtBrecht GuillemynSofie SymoensYoshi IshikawaHans Peter BachingerSophie JanssensMathieu BertrandFransiska Malfait

More to life than NF-κB in TNFR1 signaling

Adrian T TingMathieu Bertrand

A1 Journal Article in TRENDS IN IMMUNOLOGY

Poly-ubiquitination in TNFR1-mediated necroptosis

Yves DondelingerMaurice DardingMathieu BertrandHenning Walczak

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

Polyhydramnios, transient antenatal Bartter's syndrome, and MAGED2 mutations

Kamel LaghmaniBodo B BeckSung-Sen YangElie SeaayfanAndrea WenzelBjörn ReuschHelga VitzthumDario PriemSylvie DemaretzKlasien BergmannLeonie K DuinHeike GöbelChristoph MacheHolger ThieleMalte P BartramCarlos DombretJanine AltmüllerPeter NürnbergThomas BenzingElena LevtchenkoHannsjörg W SeyberthGünter KlausGökhan YigitShih-Hua LinAlbert TimmerTom J de KoningSicco A ScherjonKarl P SchlingmannMathieu BertrandMarkus M RinschenOlivier de BackerMartin KonradMartin Kömhoff

A1 Journal Article in NEW ENGLAND JOURNAL OF MEDICINE

RIPK1 protects from TNF-α-mediated liver damage during hepatitis

Aveline FilliolClaire Piquet-PellorceJacques Le SeyecMuhammad FarooqValentine GenetCatherine Lucas-ClercJohn BertinPeter J GoughMarie-Thérèse Dimanche-BoitrelPeter VandenabeeleMathieu BertrandMichel Samson

A1 Journal Article in CELL DEATH & DISEASE

Regulation of RIPK1's cell death function by phosphorylation

Yves DondelingerPeter VandenabeeleMathieu Bertrand

Editorial material

The tumor suppressor Hace1 is a critical regulator of TNFR1-mediated cell fate

Luigi TortolaRoberto NitschMathieu BertrandMelanie KoglerYounes RedouaneIvona KozieradzkiIris UribesalgoLilian M FennellMads DaugaardHelene KlugGerald WirnsbergerReiner WimmerThomas PerlotRenu SaraoShuan RaoToshikatsu HanadaNozomi TakahashiElisabeth KernbauerDuygu DemirözMichaela LangGiulio Superti-FurgaThomas DeckerAndrea PichlerFumiyo IkedaGuido KroemerPeter VandenabeelePoul H SorensenJosef M Penninger

A1 Journal Article in CELL REPORTS

Type III collagen is important for dermal and cardiovascular development, and type I collagen fibrillogenesis

Sanne D'hondtBrecht GuillemynSofie SymoensRiet De RyckeYoshi IshikawaHans Peter BachingerSophie JanssensMathieu BertrandFransiska Malfait

Type III collagen is important for type I collagen fibrillogenesis and for dermal and cardiovascular development

Sanne D'hondtBrecht GuillemynSofie SymoensRiet De RyckeYoshi IshikawaHans Peter BachingerSophie JanssensMathieu BertrandFransiska Malfait

Vaccination with necroptotic cancer cells induces efficient anti-tumor immunity

Tania Love AaesAgnieszka KaczmarekTinneke DelvaeyeBram De CraeneStefaan De KokerLiesbeth HeyndrickxIris DelrueJoachim TaminauBartosz WiernickiPhilippe De GrooteAbhishek D GargLuc LeybaertJohan GrootenMathieu BertrandPatrizia AgostinisGeert BerxWim DeclercqPeter VandenabeeleDmitri Krysko

A1 Journal Article in CELL REPORTS

2015

Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells

S SaveljevaSL Mc LaughlinPeter VandenabeeleA SamaliMathieu Bertrand

A1 Journal Article in CELL DEATH & DISEASE

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

L GalluzziJM Bravo-San PedroI VitaleSA AaronsonJM AbramsD AdamES AlnemriL AltucciD AndrewsM Annicchiarico-PetruzzelliEH BaehreckeNG BazanMathieu BertrandK BianchiMV BlagosklonnyK BlomgrenC BornerDE BredesenC BrennerM CampanellaE CandiF CecconiFK ChanNS ChandelEH ChengJE ChipukJA CidlowskiA CiechanoverTM DawsonVL DawsonV De LaurenziR De MariaK-M DebatinN Di DanieleVM DixitBD DynlachtWS El-DeiryGM FimiaRA FlavellS FuldaC GarridoM-L GougeonDR GreenH GronemeyerG HajnoczkyJM HardwickMO HengartnerH IchijoB JosephPJ JostT KaufmannO KeppDJ KlionskyRA KnightS KumarJJ LemastersB LevineA LinkermannSA LiptonRA LockshinC. López-OtínE LugliF MadeoW MalorniJ-C MarineSJ MartinJ-C MartinouJP MedemaP MeierS MelinoN MizushimaU MollC Muñoz-PinedoG NuñezA OberstT PanaretakisJM PenningerME PeterM PiacentiniP PintonJH PrehnH PuthalakathGA RabinovichKS RavichandranR RizzutoCM RodriguesDC RubinszteinT RudelY ShiH-U SimonBR StockwellG SzabadkaiSW TaitHL TangN TavernarakisY TsujimotoTom Vanden BerghePeter VandenabeeleA VillungerEF WagnerH WalczakE WhiteWG WoodJ YuanZ ZakeriB ZhivotovskyG MelinoG Kroemer

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

IAPs, regulators of innate immunity and inflammation

Yann EstornesMathieu Bertrand

A1 Journal Article in SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Molecular crosstalk between apoptosis, necroptosis, and survival signaling

Tom Vanden BergheWilliam J KaiserMathieu BertrandPeter Vandenabeele

A2 Journal Article in MOLECULAR AND CELLULAR ONCOLOGY

NF-κB-independent role of IKKα/IKKβ in preventing RIPK1 kinase-dependent apoptotic and necroptotic cell death during TNF signaling

Yves DondelingerSandrine Jouan-LanhouetTatyana DivertEmilie TheatreJohn BertinPeter J GoughPiero GiansantiAlbert JR HeckEmmanuel DejardinPeter VandenabeeleMathieu Bertrand

A1 Journal Article in MOLECULAR CELL

NIK promotes tissue destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis

L BoutaffalaMathieu BertrandC RemouchampsG SeleznikF ReisingerM JanasC BénézechMT FernandesS MarchettiF MairC GaneffA HupalowskaJ-E RicciB BecherJ PietteP KnolleJ CaamanoPeter VandenabeeleM HeikenwalderE Dejardin

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

Type III collagen is important for collagen fibrillogenesis and for dermal and cardiovascular development

Sanne D'hondtBrecht GuillemynSofie SymoensWendy ToussaintLeen VanhoutteRiet De RyckePaul CouckeBart LambrechtPatrick SegersAnne De PaepeSophie JanssensMathieu BertrandFransiska Malfait

Type III collagen is important for type I collagen fibrillogenesis and for dermal and cardiovascular development

Sanne D'hondtBrecht GuillemynSofie SymoensWendy ToussaintLeen VanhoutteRiet De RyckePaul CouckePatrick SegersBart LambrechtAnne De PaepeSophie JanssensMathieu BertrandFransiska Malfait

Unraveling the molecular mechanisms of RIPK1-mediated cell death

Yves DondelingerPeter VandenabeeleMathieu Bertrand

cIAP2 supports viability of mice lacking cIAP1 and XIAP

Kristen N HeardMathieu BertrandPhilip A Barker

A1 Journal Article in EMBO JOURNAL

2014

Caspase-3 and RasGAP: a stress-sensing survival/demise switch

Hadi KhalilMathieu BertrandPeter VandenabeeleChristian Widmann

A1 Journal Article in TRENDS IN CELL BIOLOGY

Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions

Shane DeeganSvetlana SaveljevaSusan E LogueKarolina Pakos-ZebruckaSanjeev GuptaPeter VandenabeeleMathieu BertrandAfshin Samali

A1 Journal Article in AUTOPHAGY

Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis

Quinten RemijsenSasker GrootjansC Van den HauteNele VanlangenakkerYves DondelingerRia RoelandtInge BruggemanAmanda GonçalvesMathieu BertrandV BaekelandtNozomi TakahashiTom Vanden BerghePeter Vandenabeele

A1 Journal Article in CELL DEATH & DISEASE

MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates

Yves DondelingerWim DeclercqSylvie MontessuitRia RoelandtAmanda GonçalvesInge BruggemanPaco HulpiauKathrin WeberClark A SehonRobert W MarquisJohn BertinPeter J GoughSavvas SavvidesJean-Claude MartinouMathieu BertrandPeter Vandenabeele

A1 Journal Article in CELL REPORTS

RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis

Nozomi TakahashiLars VereeckeMathieu BertrandLinde DuprezScott B BergerTatyana DivertAmanda GonçalvesMozes SzeBarbara GilbertStephanie KourulaSylvie LefebvreClaudia GüntherChristoph BeckerJohn BertinPeter J GoughWim DeclercqGeert van LooPeter Vandenabeele

A1 Journal Article in NATURE

RIPK1 promotes death receptor-independent caspase-8-mediated apoptosis under unresolved ER stress conditions

Yann EstornesMiguel AguiletaChristel DubuissonJulie De KeyserKristof KersseA SamaliPeter VandenabeeleMathieu Bertrand

A1 Journal Article in CELL DEATH & DISEASE

2013

C-propeptide mutations in procollagen type I and V are associated with endoplasmic reticulum stress-specific unfolded protein responses

Sanne D'hondtSofie SymoensSophie JanssensAnne De PaepeMathieu BertrandFransiska Malfait

RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition

Yves DondelingerMiguel AguiletaChristel DubuissonSasker GrootjansE DejardinPeter VandenabeeleMathieu Bertrand

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

2012

Intermediate domain of receptor-interacting protein kinase 1 (RIPK1) determines switch between necroptosis and RIPK1 kinase-dependent apoptosis

Linde DuprezMathieu BertrandTom Vanden BergheYves DondelingerNele FestjensPeter Vandenabeele

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Maged1 results in obesity, deficits of social interactions, impaired sexual behavior and severe alteration of mature oxytocin production in the hypothalamus

Carlos DombretTuan NguyenOlivier SchakmanJacques L MichaudHélène Hardin-PouzetMathieu BertrandOlivier De Backer

A1 Journal Article in HUMAN MOLECULAR GENETICS

RIP1 is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosis

S LoederM SchirmerH SchoenebergerS CristofanonJ LeibacherNele VanlangenakkerMathieu BertrandPeter VandenabeeleI JeremiasK-M DebatinS Fulda

A1 Journal Article in LEUKEMIA

The role of the IAP E3 ubiquitin ligases in regulating pattern-recognition receptor signalling

Peter VandenabeeleMathieu Bertrand

A1 Journal Article in NATURE REVIEWS IMMUNOLOGY

The unfolded protein response at the crossroads of cellular life and death during endoplasmic reticulum stress

Richard JägerMathieu BertrandAdrienne M GormanPeter VandenabeeleAfshin Samali

A1 Journal Article in BIOLOGY OF THE CELL

2011

Inflammasome modulation and NF-κB activation by caspase-1-related CARD domains

Kristof KerssePeter VandenabeeleTom Vanden BergheMathieu Bertrand

Interaction patches of procaspase-1 caspase recruitment domains (CARDs) are differently involved in procaspase-1 activation and receptor-interacting protein 2 (RIP2)-dependent nuclear factor κB signaling

Kristof KersseMohamed LamkanfiMathieu BertrandTom Vanden BerghePeter Vandenabeele

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

NOD-like receptors and the innate immune system: coping with danger, damage and death

Kristof KersseMathieu BertrandMohamed LamkanfiPeter Vandenabeele

A1 Journal Article in CYTOKINE & GROWTH FACTOR REVIEWS

Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosis

Bram LaukensClaudia JenneweinBarbara SchenkNele VanlangenakkerAlexander SchierSilvia CristofanonKerry ZobelKurt DeshayesDomagoj VucicIrmela JeremiasMathieu BertrandPeter VandenabeeleSimone Fulda

A1 Journal Article in NEOPLASIA

TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members

Nele VanlangenakkerMathieu BertrandPieter BogaertPeter VandenabeeleTom Vanden Berghe

A1 Journal Article in CELL DEATH & DISEASE

The Ripoptosome: death decision in the Cytosol

Mathieu BertrandPeter Vandenabeele

Editorial material

cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production

Nele VanlangenakkerTom Vanden BerghePieter BogaertBram LaukensK ZobelK DeshayesD VucicS FuldaPeter VandenabeeleMathieu Bertrand

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)

Mathieu BertrandSaskia LippensAn StaesBarbara GilbertRia RoelandtJelle De MedtsKris GevaertWim DeclercqPeter Vandenabeele

A1 Journal Article in PLOS ONE

2010

Maged1, a new regulator of skeletal myogenic differentiation and muscle regeneration

Tuan HN NguyenMathieu BertrandChristiane SterpinYounes AchouriOlivier RY De Backer

A1 Journal Article in BMC CELL BIOLOGY

RIP1's function in NF-kappa B activation: from master actor to onlooker

Mathieu BertrandPeter Vandenabeele

Editorial material