Research Explorer

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Researcher

Massimo Marzorati

Awards & Distinctions

128 Results

2024

AG1® induces a favorable impact on gut microbial structure and functionality in the Simulator of Human Intestinal Microbial Ecosystem® model

Trevor O. KirbyPhilip A. SappJeremy R. TownsendMarlies GovaertCindy DuysburghMassimo MarzoratiTess M. MarshallRalph Esposito

A1 Journal Article in CURRENT ISSUES IN MOLECULAR BIOLOGY

AG1®, a novel synbiotic, maintains gut barrier function following inflammatory challenge in a Caco-2/THP1-Blue™ co-culture model

Philip A. SappJeremy R. TownsendTrevor O. KirbyMarlies GovaertCindy DuysburghLynn VerstrepenMassimo MarzoratiTess M. MarshallRalph Esposito

A1 Journal Article in MICROORGANISMS

Changes in the fecal polar metabolome due to AG1 supplementation in the SHIME® model : a proof of principle study

Trevor O. KirbyPhilip A. SappJeremy R. TownsendMarlies GovaertCindy DuysburghMassimo MarzoratiTess M. MarshallRalph Esposito

A1 Journal Article in JOURNAL OF FUNCTIONAL FOODS

Co-supplementation of baobab fiber and arabic gum synergistically modulates the in vitro human gut microbiome revealing complementary and promising prebiotic properties

Cindy DuysburghMarlies GovaertDamien GuillemetMassimo Marzorati

A1 Journal Article in NUTRIENTS

Saccharomyces cerevisiae derived postbiotic alters gut microbiome metabolism in the human distal colon resulting in immunomodulatory potential n vitro

Cindy DuysburghLisa MiclotteJustin B. GreenKevin T. WattsMaria I. SardiAnirikh ChakrabartiEhsan KhafipourMassimo Marzorati

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

The colon targeting efficacies of mesalazine medications and their impacts on the gut microbiome

Laura E. MccoubreyNidhi SeegobinNannapat SangfuangFrederic MoensHans DuyvejonckEline DeclerckArno DierickMassimo MarzoratiAbdul W. Basit

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

2023

Age-dependent prebiotic effects of soluble corn fiber in M-SHIME® gut microbial ecosystems

Marta Calatayud ArroyoIeva LaurieChloe RotsaertMassimo MarzoratiDavide RissoKavita Karnik

A1 Journal Article in PLANT FOODS FOR HUMAN NUTRITION

Amino acid digestibility of different formulations of torula yeast in an in vitro porcine gastrointestinal digestion model and their protective effects on barrier function and inflammation in a Caco-2/THP1Co-culture model

Lynn VerstrepenMarta Calatayud ArroyoCindy DuysburghJelle De MedtsRicardo D. EkmayMassimo Marzorati

A1 Journal Article in ANIMALS

Capacity of a microbial synbiotic to rescue the in vitro metabolic activity of the gut microbiome following perturbation with alcohol or antibiotics

Braden T. TierneyPieter Van den AbbeeleGabriel A. Al-GhalithLynn VerstrepenJonas GhyselinckMarta Calatayud ArroyoMassimo MarzoratiAzza A. GadirBrendan DaisleyGregor Reid et al.

A1 Journal Article in APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Ex vivo colonic fermentation of NUTRIOSE® exerts immuno-modulatory properties and strong anti-inflammatory effects

Caroline PerreauClementine ThabuisLynn VerstrepenJonas GhyselinckMassimo Marzorati

A1 Journal Article in NUTRIENTS

In vitro effect of enzymes and human milk oligosaccharides on FODMAP digestion and fecal microbiota composition

Van T. PhamRobert E. SteinertCindy DuysburghJonas GhyselinckMassimo MarzoratiPeter J. T. Dekker

A1 Journal Article in NUTRIENTS

In vitro evaluation of the gastrointestinal delivery of acid-sensitive pancrelipase in a next generation enteric capsule using an exocrine pancreatic insufficiency disease model

Vincent JanninCindy DuysburghVanessa GonzalezMarlies GovaertMarine AgissonMassimo MarzoratiNicolas Madit

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Infant fecal fermentations with galacto-oligosaccharides and 2'-fucosyllactose show differential bifidobacterium longum stimulation at subspecies level

Cordula LindnerEllen LooijesteijnHelmie van DijckIngeborg Bovee-OudenhovenMargreet HeerikhuisenTim J. van den BroekMassimo MarzoratiVassilis TriantisArjen Nauta

A1 Journal Article in CHILDREN-BASEL

The Dynamic Intestinal Absorption Model (Diamod®), an in vitro tool to study the interconnected kinetics of gastrointestinal solubility, supersaturation, precipitation, and intestinal permeation processes of oral drugs

Frederic MoensGies VandevijverAnke De BlaiserAdam LarssonFabio SpreaficoPatrick AugustijnsMassimo Marzorati

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS-X

The intricate connection between bacterial α-diversity and fungal engraftment in the human gut of healthy and impaired individuals as studied using the in vitro SHIME® model

Benoît MarsauxFrederic MoensMassimo MarzoratiTom Van de Wiele

A1 Journal Article in JOURNAL OF FUNGI

2022

Co-administration of lactulose crystals with amoxicillin followed by prolonged lactulose treatment promotes recovery of the human gut microbiome in vitro

Cindy DuysburghPieter van den AbbeeleDennis FranckensteinMartin WestphalAngelika Kuchinka-KochMassimo Marzorati

A1 Journal Article in ANTIBIOTICS-BASEL

Effects of combined prebiotic, probiotic, IgG and amino acid supplementation on the gut microbiome of patients with inflammatory bowel disease

Massimo MarzoratiSarah BubeckThomas BayneKiran KrishnanMorgan Giusto

A1 Journal Article in FUTURE MICROBIOLOGY

Human milk oligosaccharides and lactose differentially affect infant gut microbiota and intestinal barrier in vitro

Jane Mea NatividadBenoît MarsauxClara Lucia Garcia RodenasAndreas RytzGies VandevijverMassimo MarzoratiPieter Van den AbbeeleMarta Calatayud ArroyoFlorence Rochat

A1 Journal Article in NUTRIENTS

Long-term lactulose administration improves dysbiosis induced by antibiotic and C. difficile in the PathoGut (TM) SHIME model

Marta Calatayud ArroyoCindy DuysburghPieter Van den AbbeeleDennis FranckensteinAngelika Kuchina-KochMassimo Marzorati

A1 Journal Article in ANTIBIOTICS-BASEL

The effect of amino acids on production of SCFA and bCFA by members of the porcine colonic microbiota

Pieter Van den AbbeeleJonas GhyselinckMassimo MarzoratiAnna-Maria KochWilliam LambertJoris MichielsTristan Chalvon-Demersay

A1 Journal Article in MICROORGANISMS

The modulation of Chaihu Shugan Formula on microbiota composition in the simulator of the human intestinal microbial ecosystem technology platform and its influence on gut barrier and intestinal immunity in Caco-2/THP1-blue (TM) cell co-culture model

Ling LiuYi LuChao XuHaitao ChenXuanying WangYijie WangBiyu CaiBing LiLynn VerstrepenJonas Ghyselinck et al.

A1 Journal Article in FRONTIERS IN PHARMACOLOGY

2021

2 ' FL and LNnT exert antipathogenic effects against C. difficile ATCC 9689 in vitro, coinciding with increased levels of Bifidobacteriaceae and/or secondary bile acids

Louise Kristine VigsnaesJonas GhyselinckPieter van den AbbeeleBruce McConnellFrederic MoensMassimo MarzoratiDanica Bajic

A1 Journal Article in PATHOGENS

A comparison of the in vitro effects of 2'fucosyllactose and lactose on the composition and activity of gut microbiota from infants and toddlers

Pieter Van den AbbeeleNorbert SprengerJonas GhyselinckBenoît MarsauxMassimo MarzoratiFlorence Rochat

A1 Journal Article in NUTRIENTS

A cranberry concentrate decreases adhesion and invasion of Escherichia coli (AIEC) LF82 in vitro

Derek ZhangLynn VerstrepenJelle De MedtsCindy DuysburghPieter Van den AbbeeleMassimo MarzoratiChristina Khoo

A1 Journal Article in PATHOGENS

A pectin-rich, baobab fruit pulp powder exerts prebiotic potential on the human gut microbiome in vitro

Martin FoltzAlicia Christin ZahradnikPieter Van den AbbeeleJonas GhyselinckMassimo Marzorati

A1 Journal Article in MICROORGANISMS

Antioxidant vitamins and prebiotic FOS and XOS differentially shift microbiota composition and function and improve intestinal epithelial barrier in vitro

Van T. PhamMarta Calatayud ArroyoChloe RotsaertNicole SeifertNathalie RichardPieter Van den AbbeeleMassimo MarzoratiRobert E. Steinert

A1 Journal Article in NUTRIENTS

Chitin glucan shifts luminal and mucosal microbial communities, improve epithelial barrier and modulates cytokine production in vitro

Marta Calatayud ArroyoLynn VerstrepenJonas GhyselinckPieter Van den AbbeeleMassimo MarzoratiSalvatore ModicaThibaut RanjanoroVeronique Maquet

A1 Journal Article in NUTRIENTS

Comparison of protection and release behavior of different capsule polymer combinations based on L. acidophilus survivability and function and caffeine release

Massimo MarzoratiMarta Calatayud ArroyoChloe RotsaertMichiel Van MeleCindy DuysburghShane DurkeeTyler WhiteKelli FowlerVincent JanninAouatef Bellamine

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Consistent prebiotic effects of carrot RG-I on the gut microbiota of four human adult donors in the SHIME® model despite baseline individual variability

Pieter Van den AbbeeleCindy DuysburghIlse CleenwerckRuud AlbersMassimo MarzoratiAnnick Mercenier

A1 Journal Article in MICROORGANISMS

Evaluation of the effect of food products containing prebiotics and bacillus subtilis HU58 on the gut microbial community activity and community composition using an in vitro M-SHIME(R) model

Massimo MarzoratiSarah BubeckThomas BayneKiran KrishnanAicacia Young

A1 Journal Article in APPLIED SCIENCES-BASEL

Fructans with varying degree of polymerization enhance the selective growth of Bifidobacterium animalis subsp. lactis BB-12 in the human gut microbiome in vitro

Pieter Van den AbbeeleCindy DuysburghJonas GhyselinckShellen GoltzYulia BerezhnayaThomas BoileauAnke De BlaiserMassimo Marzorati

A1 Journal Article in APPLIED SCIENCES-BASEL

In vitro evaluation of the anti-pathogenic activity of Okoubaka aubrevillei on the human gastrointestinal tract

Susann Buchheim-SchmidtUwe PetersCindy DuysburghPieter Van den AbbeeleMassimo MarzoratiThomas KellerDavid MartinPetra KlementStephan Baumgartner

A1 Journal Article in ZEITSCHRIFT FUR GASTROENTEROLOGIE

In vitro-in vivo validation of stimulatory effect of oat ingredients on lactobacilli

Cindy DuysburghPieter Van den AbbeeleAlison KamilLisa FleigePeter John De ChavezYiFang ChuWiley BartonOrla O'SullivanPaul D. CotterKarina Quilter et al.

A1 Journal Article in PATHOGENS

Inclusion of small intestinal absorption and simulated mucosal surfaces further improve the Mucosal Simulator of the Canine Intestinal Microbial Ecosystem (M-SCIME™)

Lynn VerstrepenPieter Van den AbbeeleGiulia PignataroCataldo RibeccoAlessandro GramenziMyriam HestaMassimo Marzorati

A1 Journal Article in RESEARCH IN VETERINARY SCIENCE

Lacticaseibacillus rhamnosus GG and Saccharomyces cerevisiae boulardii supplementation exert protective effects on human gut microbiome following antibiotic administration in vitro

C. DuysburghP. Van den AbbeeleM. MoreraMassimo Marzorati

A1 Journal Article in BENEFICIAL MICROBES

Microbial fermentation of Fossence (TM), a short-chain fructo-oligosaccharide, under simulated human proximal colonic condition and assessment of its prebiotic effects-a pilot study

Deepika P. TiwariPriyali ShahPieter Van den AbbeeleMassimo MarzoratiMarta Calatayud ArroyoJonas GhyselinckAshok Kumar DubeyS. NarayananManish Jain

A1 Journal Article in FEMS MICROBIOLOGY LETTERS

Mucin as a functional niche is a more important driver of in vitro gut microbiota composition and functionality than Akkermansia muciniphila supplementation

Florence Van HerreweghenKim De PaepeMassimo MarzoratiTom Van de Wiele

A1 Journal Article in APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Treatment with a spore-based probiotic containing five strains of Bacillus induced changes in the metabolic activity and community composition of the gut microbiota in a SHIME® model of the human gastrointestinal system

Massimo MarzoratiPieter Van den AbbeeleSarah BubeckThomas BayneKiran KrishnanAicacia Young

A1 Journal Article in FOOD RESEARCH INTERNATIONAL

Water kefir and derived pasteurized beverages modulate gut microbiota, intestinal permeability and cytokine production in vitro

Marta Calatayud ArroyoRosa Aragao BoernerJonas GhyselinckLynn VerstrepenJelle De MedtsPieter Van den AbbeeleClaire L. BoulangeSarah PriourMassimo MarzoratiSami Damak

A1 Journal Article in NUTRIENTS

2020

A novel non-digestible, carrot-derived polysaccharide (cRG-I) selectively modulates the human gut microbiota while promoting gut barrier integrity : an integrated in vitro approach

Pieter Van den AbbeeleLynn VerstrepenJonas GhyselinckRuud AlbersMassimo MarzoratiAnnick Mercenier

A1 Journal Article in NUTRIENTS

Bacillus subtilis HU58 and Bacillus coagulans SC208 probiotics reduced the effects of antibiotic-induced gut microbiome dysbiosis in an M-SHIME® model

Massimo MarzoratiPieter Van den AbbeeleSarah S. BubeckThomas BayneKiran KrishnanAicacia YoungDilip MehtaAnselm DeSouza

A1 Journal Article in MICROORGANISMS

Comparison of the effects of soluble corn fiber and fructooligosaccharides on metabolism, inflammation, and gut microbiome of high-fat diet-fed mice

Matthias Van HulKavita KarnikKirstie Canene-AdamsMervyn De SouzaPieter Van den AbbeeleMassimo MarzoratiNathalie M. DelzenneAmandine EverardPatrice D. Cani

A1 Journal Article in AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Development and validation of the simulator of the Canine Intestinal Microbial Ecosystem (SCIME)

Cindy DuysburghWendy OssieurKim De PaepePieter Van den AbbeeleRamiro Vichez-VargasMarius VitalDietmar H. PieperTom Van de WieleMyriam HestaSam Possemiers et al.

A1 Journal Article in JOURNAL OF ANIMAL SCIENCE

Dried yeast cell walls high in beta-glucan and mannan-oligosaccharides positively affect microbial composition and activity in the canine gastrointestinal tract in vitro

Pieter Van den AbbeeleCindy DuysburghMaike RakebrandtMassimo Marzorati

A1 Journal Article in JOURNAL OF ANIMAL SCIENCE

Fate and bioaccessibility of iodine in food prepared from agronomically biofortified wheat and rice and impact of cofertilization with zinc and selenium

Ismail CakmakMassimo MarzoratiPieter Van den AbbeeleKatja HoraHarmen Tjalling HolwerdaMustafa Atilla YaziciErdinc SavasliJoachim NeriGijs Du Laing

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Synbiotic effect of Bifidobacterium lactis CNCM I-3446 and bovine milk-derived oligosaccharides on infant gut microbiota

Benoît MarsauxPieter Van den AbbeeleJonas GhyselinckGuenolee PrioultMassimo MarzoratiBiljana Bogicevic

A1 Journal Article in NUTRIENTS

Yeast-derived formulations are differentially fermented by the canine and feline microbiome as assessed in a novel in vitro colonic fermentation model

Pieter Van den AbbeeleFrederic MoensGiulia PignataroJudy SchnurrCataldo RibeccoAlessandro GramenziMassimo Marzorati

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

2019

2'-Fucosyllactose alters the composition and activity of gut microbiota from formula-fed infants receiving complementary feeding in a validated intestinal model

P Van den AbbeeleC DuysburghE VazquezJ ChowR BuckMassimo Marzorati

A1 Journal Article in JOURNAL OF FUNCTIONAL FOODS

A listeria monocytogenes bacteriocin can target the commensal prevotella copri and modulate intestinal infection

Nathalie RolhionBenoit ChassaingMarie-Anne NahoriJana De BodtAlexandra MouraMarc LecuitOlivier DussurgetMarion BerardMassimo MarzoratiHannah Fehlner-Peach et al.

A1 Journal Article in CELL HOST & MICROBE

A synbiotic concept containing spore-forming Bacillus strains and a prebiotic fiber blend consistently enhanced metabolic activity by modulation of the gut microbiome in vitro

Cindy DuysburghPieter Van den AbbeeleKiran KrishnanThomas F. BayneMassimo Marzorati

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS-X

Baby-SPIME : a dynamic in vitro piglet model mimicking gut microbiota during the weaning process

Sandrine DufournyNadia EveraertSarah LebrunCaroline DounyMarie-Louise ScippoBing LiBernard TaminiauMassimo MarzoratiJose WavreilleEric Froidmont et al.

A1 Journal Article in JOURNAL OF MICROBIOLOGICAL METHODS

Development of an analytical method to detect short-chain fatty acids by SPME-GC-MS in samples coming from an in vitro gastrointestinal model

Caroline DounySandrine DufournyFrancois BrosePauline VerachtertPierre RondiaSarah LebrunMassimo MarzoratiNadia EveraertVeronique DelcenserieMarie-Louise Scippo

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Effects of olive and pomegranate by-products on human microbiota : a study using the SHIME (R) in vitro simulator

Camilla GiulianiMassimo MarzoratiMatteo DaghioAndrea FranzettiMarzia InnocentiTom Van de WieleNadia Mulinacci

A1 Journal Article in MOLECULES

Lactobacillus rhamnosus GG and Saccharomyces cerevisiae boulardii exert synergistic antipathogenic activity in vitro against enterotoxigenic Escherichia coli

F. MoensC. DuysburghP. van den AbbeeleM. MoreraMassimo Marzorati

A1 Journal Article in BENEFICIAL MICROBES

2018

A combination of xylooligosaccharides and a polyphenol blend affect microbial composition and activity in the distal colon exerting immunomodulating properties on human cells

Pieter Van den AbbeeleCindy DuysburghT Alan JiangMarco RebazaIris PinheiroMassimo Marzorati

A1 Journal Article in JOURNAL OF FUNCTIONAL FOODS

Arabinoxylo-oligosaccharides and inulin impact inter-individual variation on microbial metabolism and composition, which immunomodulates human cells

Pieter Van den AbbeeleBernard TaminiauIris PinheiroCindy DuysburghHeidi JacobsLoek PijlsMassimo Marzorati

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Different oat ingredients stimulate specific microbial metabolites in the gut microbiome of three human individuals in vitro

Pieter Van den AbbeeleAlison KamilLisa FleigeYongsoo ChungPeter De ChavezMassimo Marzorati

A1 Journal Article in ACS OMEGA

Reinforcement of intestinal epithelial barrier by arabinoxylans in overweight and obese subjects : a randomized controlled trial Arabinoxylans in gut barrier

Bouke N. SaldenFreddy J. TroostEllen WilmsPilar TruchadoRamiro Vilchez-VargasDietmar H PieperRuy JaureguiMassimo MarzoratiTom Van de WieleSam Possemiers et al.

A1 Journal Article in CLINICAL NUTRITION

Specific members of the human gut microbiome colonize wheat bran-based dietary platforms, thus driving the production of health-related microbial metabolites

Pieter Van den AbbeeleKim De PaepeMassimo MarzoratiTom Van de Wiele

2017

A yeast fermentate improves gastrointestinal discomfort and constipation by modulation of the gut microbiome : results from a randomized double-blind placebo-controlled pilot trial

Iris PinheiroLarry RobinsonAn VerhelstMassimo MarzoratiBjörn WinkensPieter van den AbbeeleSam Possemiers

A1 Journal Article in BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE

Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo potentiating intestinal inflammation

Benoit ChassaingTom Van de WieleJana De BodtMassimo MarzoratiAndrew T. Gewirtz

A1 Journal Article in GUT

Fate of chitin-glucan in the human gastrointestinal tract as studied in a dynamic gut simulator (SHIME®)

Massimo MarzoratiVéronique MaquetSam Possemiers

A1 Journal Article in JOURNAL OF FUNCTIONAL FOODS

High-fiber and high-protein diets shape different gut microbial communities, which ecologically behave similarly under stress conditions, as shown in a gastrointestinal simulator

Massimo MarzoratiRamiro Vilchez VargasJulie Vanden BusschePilar TruchadoRuy JaureguiRacha El HageDietmar H PieperLynn VanhaeckeTom Van de Wiele

A1 Journal Article in MOLECULAR NUTRITION & FOOD RESEARCH

The response of canine faecal microbiota to increased dietary protein is influenced by body condition

Jia XuAdronie VerbruggheMarta Ribeiro Alves LourençoAn CoolsDaisy LiuTom Van de WieleMassimo MarzoratiVenessa EeckhautFilip Van ImmerseelLynn Vanhaecke et al.

A1 Journal Article in BMC VETERINARY RESEARCH

2016

An advanced in vitro technology platform to study the mechanism of action of prebiotics and probiotics in the gastrointestinal tract

Massimo MarzoratiTom Van de Wiele

A1 Journal Article in JOURNAL OF CLINICAL GASTROENTEROLOGY

Arabinogalactan and fructooligosaccharides improve the gut barrier function in distinct areas of the colon in the Simulator of the Human Intestinal Microbial Ecosystem

David DaguetIris PinheiroAn VerhelstSam PossemiersMassimo Marzorati

A1 Journal Article in JOURNAL OF FUNCTIONAL FOODS

Arabinoxylans, inulin and Lactobacillus reuteri 1063 repress the adherent-invasive Escherichia coli from mucus in a musosa-comprising gut model

Pieter Van den AbbeeleMassimo MarzoratiMelanie DerdeRosemarie De WeirdtJoan VermeirenSam PossemiersTom Van de Wiele

A1 Journal Article in NPJ BIOFILMS AND MICROBIOMES

Dietary supplement based on stilbenes : a focus on gut microbial metabolism by the in vitro simulator M-SHIME®

Camilla GiulianiMassimo MarzoratiMarzia InnocentiRamiro Vilchez VargasMarius VitalDietmar H PieperTom Van de WieleNadia Mulinacci

A1 Journal Article in FOOD & FUNCTION

Enhanced removal of petroleum hydrocarbons using a bioelectrochemical remediation system with pre-cultured anodes

Krishnaveni VenkidusamyMallavarapu MegharajMassimo MarzoratiRobin LockingtonRavi Naidu

A1 Journal Article in SCIENCE OF THE TOTAL ENVIRONMENT

How the microbiota shapes rheumatic diseases

Tom Van de WieleJens Van PraetMassimo MarzoratiMichael DrennanDirk Elewaut

A1 Journal Article in NATURE REVIEWS RHEUMATOLOGY

Satiety innovations : food products to assist consumers with weight loss, evidence on the role of satiety in healthy eating : overview and in vitro approximation

Rubén López-NicolásMassimo MarzoratiLia ScarabottoloJason CG HalfordAlexandra M JohnstoneCarmen Frontela-SasetaAngel M SanmartinGaspar Ros-BerruezoJoanne A Harrold

A1 Journal Article in CURRENT OBESITY REPORTS

2015

A novel hypromellose capsule, with acid resistance properties, permits the targeted delivery of acid-sensitive products to the intestine

Massimo MarzoratiSam PossemiersAn VerhelstDominique CadéNicolas MaditTom Van de Wiele

A1 Journal Article in LWT-FOOD SCIENCE AND TECHNOLOGY

Acacia gum improves the gut barrier functionality in vitro

David DaguetIris PinheiroAn VerhelstSam PossemiersMassimo Marzorati

A1 Journal Article in AGRO FOOD INDUSTRY HI-TECH

Addition of acacia gum to a FOS/inulin blend improves its fermentation profile in the Simulator of the Human Intestinal Microbial Ecosystem (SHIME®)

Massimo MarzoratiBingcai QinFalk HildebrandAbby KlosterbuerZamzam RougheadClaudia RoessleFlorence RochatJeroen RaesSam Possemiers

A1 Journal Article in JOURNAL OF FUNCTIONAL FOODS

Diverse reductive dehalogenases are associated with Clostridiales-enriched microcosms dechlorinating 1,2-dichloroethane

Giuseppe MerlinoAnnalisa BalloiMassimo MarzoratiFrancesca MapelliAurora RizziDavide LavazzaFrancesca de FerraGiovanna CarpaniDaniele Daffonchio

A1 Journal Article in BIOMED RESEARCH INTERNATIONAL

Opportuniteiten voor de volgende generatie probiotica

Kim De PaepeFlorence Van HerreweghenPieter Van den AbbeeleAnnelies GeirnaertMassimo MarzoratiTom Van De Wiele

A4 Journal Article in FS & LAW

Validated high resolution mass spectrometry-based approach for metabolomic fingerprinting of the human gut phenotype

Julie Vanden BusscheMassimo MarzoratiDebby LaukensLynn Vanhaecke

A1 Journal Article in ANALYTICAL CHEMISTRY

2014

Effects of wheat bran extract containing arabinoxylan oligosaccharides on gastrointestinal parameters in healthy preadolescent children

Isabelle EJA FrançoisOlivier LescroartWim S VeraverbekeMassimo MarzoratiSam PossemiersHenrike HamerKaren WindeyGjalt W WellingJan A DelcourChristophe M Courtin et al.

A1 Journal Article in JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Lactobacillus-dominated cervicovaginal microbiota associated with reduced HIV/STI prevalence and genital HIV viral load in African women

Hanneke BorgdorffEvgeni TsivtsivadzeRita VerhelstMassimo MarzoratiSuzanne JurriaansGilles F NdayisabaFrank H SchurenJanneke HHM van de Wijgert

A1 Journal Article in ISME JOURNAL

Models of the human microbiota and microbiome in vitro

Massimo MarzoratiPieter Van den AbbeeleCharlotte GrootaertRosemarie De WeirdtAne Marcos CarcavillaJoan VermeirenTom Van de Wiele

Bookchapter in The human microbiota and microbiome

Synthetic microbial ecosystems : an exciting tool to understand and apply microbial communities

Karen De RoyMassimo MarzoratiPieter Van den AbbeeleTom Van de WieleNico Boon

A1 Journal Article in ENVIRONMENTAL MICROBIOLOGY

The HMI™ module: a new tool to study the host-microbiota interaction in the human gastrointestinal tract in vitro

Massimo MarzoratiBarbara VanhoeckeTine De RyckMehdi Sadaghian SadabadIris PinheiroSam PossemiersPieter Van den AbbeeleLara DeryckeMarc BrackeJan Pieters et al.

A1 Journal Article in BMC MICROBIOLOGY

2013

A dried yeast fermentate selectively modulates both the luminal and mucosal gut microbiota and protects against inflammation, as studied in an integrated in vitro approach

Sam PossemiersIris PinheiroAn VerhelstPieter Van den AbbeeleLoïs MaignienDebby LaukensStuart G ReevesLarry E RobinsonThomas RaasYves-Jacques Schneider et al.

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Application of a molecular based approach for the early detection of short term 3-chloroaniline shock loads on activated sludge bacterial community and functionality

Massimo MarzoratiAndrea NegroniFabio FavaWilly VerstraeteNico Boon

A1 Journal Article in NEW BIOTECHNOLOGY

Arabinogalactan and fructo-oligosaccharides have a different fermentation profile in the Simulator of the Human Intestinal Microbial Ecosystem (SHIME®)

Kathleen TerpendSam PossemiersDavid DaguetMassimo Marzorati

A1 Journal Article in ENVIRONMENTAL MICROBIOLOGY REPORTS

Barcoded pyrosequencing analysis of the microbial community in a simulator of the human gastrointestinal tract showed a colon region-specific microbiota modulation for two plant-derived polysaccharide blends

Massimo MarzoratiLoïs MaignienAn VerhelstGabriela LutaRobert SinnottFrederiek-Maarten KerckhofNico BoonTom Van de WieleSam Possemiers

A1 Journal Article in ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Development of integrated in vitro gut model platforms to study fiber fermentation and gut immune effects

Sam PossemiersI PinheiroC DuysburghI ScheirlinckMassimo Marzorati

Environmental conditions and community eveness determine the outcome of biological invasion

Karen De RoyMassimo MarzoratiAndrea NegroniOlivier ThasAnnalisa BalloiFabio FavaWilly VerstraeteDaniele DaffonchioNico Boon

A1 Journal Article in NATURE COMMUNICATIONS

Environmental conditions and community evenness determine the outcome of biological invasion

Karen De RoyMassimo MarzoratiAndrea NegroniOlivier ThasAnnalisa BalloiFabrio FavaDaniele DaffonchioWilly VerstraeteNico Boon

Impact of polyphenols from black tea and red wine/grape juice on a gut model microbiome

Rober A KempermanGabriele GrossStanilas MondotSam PossemiersMassimo MarzoratiTom Van de WieleJoël DoréElaine E Vaughan

A1 Journal Article in FOOD RESEARCH INTERNATIONAL

Lactobacillus crispatus-dominated cervicovaginal microbiome associated with fewer sexually transmitted infections in African sex workers

Hanneke BorgdorffEvgeni TsivtsivadzeRita VerhelstMassimo MarzoratiGilles NdayisabaFrank SchurenJanneke van de Wijgert

Microbial symbionts of honeybees: a promising tool to improve honeybee health

Elena CrottiLuigi SansonnoErica M ProsdocimiVioletta VacchiniChadlia HamdiAmeur CherifElena GonellaMassimo MarzoratiAnnalisa Balloi

A1 Journal Article in NEW BIOTECHNOLOGY

Synthetic microbial communities: high throughput models to test new ecological hypothesis

Karen De RoyMassimo MarzoratiAndrea NegroniOlivier ThasAnnalisa BalloiFabio FavaWilly VerstraeteDaniele DaffonchioNico Boon

The vaginal microbiome and its clinical correlates in a cohort of African sex workers

Hanneke BorgdorffEvgeni TsivtsivadzeRita VerhelstFrank SchurenMassimo MarzoratiJanneke van de Wijgert

2012

An in vitro technology platform to assess host-microbiota interactions in the gastrointestinal tract

Massimo MarzoratiIris PinheiroPieter Van den AbbeeleTom Van de WieleSam Possemiers

A1 Journal Article in AGRO FOOD INDUSTRY HI-TECH

Effects of a wheat bran extract containing arabinoxylan oligosaccharides on gastrointestinal health parameters in healthy adult human volunteers : a double-blind, randomised, placebo-controlled, cross-over trial

Isabelle EJA FrancoisOlivier LescroartWim S VeraverbekeMassimo MarzoratiSam PossemiersPieter EvenepoelHenrike HamerEls HoubenKaren WindeyGjalt W Welling et al.

A1 Journal Article in BRITISH JOURNAL OF NUTRITION

Effects of poly-β-hydroxybutyrate (PHB) on Siberian sturgeon (Acipenser baerii) fingerlings performance and its gastrointestinal tract microbial community

Ebrahim Hossein NajdegeramiNgoc Tran TietTom DefoirdtMassimo MarzoratiPatrick SorgeloosNico BoonPeter Bossier

A1 Journal Article in FEMS MICROBIOLOGY ECOLOGY

Incorporating a mucosal environment in a dynamic gut model results in a more representative colonization by lactobacilli

Pieter Van den AbbeeleStefaan RoosVenessa EeckhautDonald A MacKenzieMelanie DerdeWilly VerstraeteMassimo MarzoratiSam PossemiersBarbara VanhoeckeFilip Van Immerseel et al.

A1 Journal Article in MICROBIAL BIOTECHNOLOGY

Microbial symbionts : a resource for the management of insect-related problems

Elena CrottiAnnalisa BalloiChadlia HamdiLuigi SansonnoMassimo MarzoratiElena GonellaGuido FaviaAmeur CherifClaudio BandiAlberto Alma et al.

A1 Journal Article in MICROBIAL BIOTECHNOLOGY

2011

Addition of an aerated iron-rich waste-activated sludge to control the soluble sulphide concentration in sewage

Lehua ZhangBart De GussemeLankun CaiPeter De SchryverMassimo MarzoratiNico BoonPiet LensWilly Verstraete

A1 Journal Article in WATER AND ENVIRONMENT JOURNAL

Convergent dynamics of the juvenile European sea bass gut microbiota induced by poly-beta-hydroxybutyrate

Peter De SchryverKristof DierckensThi Quyen Quyen BanhRezki AmaliaMassimo MarzoratiPeter BossierNico BoonWilly Verstraete

A1 Journal Article in ENVIRONMENTAL MICROBIOLOGY

Microbial resource management revisited: successful parameters and new concepts

Suzanne ReadMassimo MarzoratiBeatriz Morais GuimarãesNico Boon

A1 Journal Article in APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Nutrient gradients in a granular activated carbon biofilter drives bacterial community organization and dynamics

Nico BoonBenny PyckeMassimo MarzoratiFrederik Hammes

A1 Journal Article in WATER RESEARCH

Prebiotics to manage the microbial control of energy homeostasis

Charlotte GrootaertMassimo MarzoratiPieter Van den AbbeeleTom Van de WieleSam Possemiers

A1 Journal Article in BENEFICIAL MICROBES

Studying the host-microbiota interaction in the human gastrointestinal tract: basic concepts and in vitro approaches

Massimo MarzoratiPieter Van den AbbeeleSam PossemiersJessica BennerWilly VerstraeteTom Van de Wiele

A1 Journal Article in ANNALS OF MICROBIOLOGY

The gut microbiota as a target for innovative drug development: perspectives and a case study of inflammatory bowel diseases

Joan VermeirenSam PossemiersMassimo MarzoratiTom Van de Wiele

Bookchapter in Drug development : a case study based insight into modern strategies

Upgrading of straw hydrolysate for production of hydrogen and phenols in a microbial electrolysis cell (MEC)

Anders ThygesenMassimo MarzoratiNico BoonAnne Belinda ThomsenWilly Verstraete

A1 Journal Article in APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

2010

An innovative in vitro system to study the host-microbiota interaction in the gut under long-term conditions

Massimo MarzoratiBarbara VanhoeckeTom Van de WieleSam PossemiersWilly VerstraetePieter Van den Abbeele

Bacteria and chocolate: a successful combination for probiotic delivery

Sam PossemiersMassimo MarzoratiWilly VerstraeteTom Van de Wiele

A1 Journal Article in INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Bacterial diversity and reductive dehalogenase redundancy in a 1,2-dichloroethane-degrading bacterial consortium enriched from a contaminated aquifer

Massimo MarzoratiAnnalisa BalloiFrancesca de FerraLorenzo CoralloGiovanna CarpaniLieven WittebolleWilly VerstraeteDaniele Daffonchio

A1 Journal Article in MICROBIAL CELL FACTORIES

In vitro modulation of the human gastrointestinal microbial community by plant-derived polysaccharide-rich dietary supplements

Massimo MarzoratiA VerhelstG LutaR SinnottWilly VerstraeteTom Van de WieleSam Possemiers

A1 Journal Article in INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Incorporation of a mucosal environment in a dynamic gut model results in a more representative colonization by lactobacilli

Pieter Van den AbbeeleVenessa EeckhautMassimo MarzoratiSam PossemiersBarbara VanhoeckeWilly VerstraeteFilip Van ImmerseelTom Van de Wiele

Microbial community analysis of anodes from sediment microbial fuel cells powered by rhizodeposits of living rice plants

Liesje De SchamphelaireAngela CabezasMassimo MarzoratiMichael W FriedrichNico BoonWilly Verstraete

A1 Journal Article in APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Microbial community development in a dynamic gut model is reproducible, colon region specific, and selective for Bacteroidetes and Clostridium cluster IX

Pieter Van den AbbeeleCharlotte GrootaertMassimo MarzoratiSam PossemiersWilly VerstraetePhilippe GerardSylvie RabotAurelia BruneauSahar El AidyMuriel Derrien et al.

A1 Journal Article in APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Mucin-coated surfaces in dynamic gut models demonstrate the species-specificity of probiotic colonization

Pieter Van den AbbeeleTom Van de WieleMassimo MarzoratiWilly VerstraeteSam Possemiers

2009

Arabinoxylan-oligosaccharides (AXOS) affect the protein/carbohydrate fermentation balance and microbial population dynamics of the Simulator of Human Intestinal Microbial Ecosystem

JI SanchezMassimo MarzoratiCharlotte GrootaertM BaranV Van CraeyveldCM CourtinWF BroekaertJA DelcourWilly VerstraeteTom Van de Wiele

A1 Journal Article in MICROBIAL BIOTECHNOLOGY

Comparison of prebiotic effects of arabinoxylan oligosaccharides and inulin in a simulator of the human intestinal microbial ecosystem

Charlotte GrootaertPieter Van den AbbeeleMassimo MarzoratiWillem F BroeckaertChristophe M CourtinJan A DelcourWilly VerstraeteTom Van de Wiele

A1 Journal Article in FEMS MICROBIOLOGY ECOLOGY

Decreasing sulfide generation in sewage by dosing formaldehyde and its derivatives under anaerobic conditions

LeHua ZhangBart De GussemePeter De SchryverL MendozaMassimo MarzoratiWilly Verstraete

A1 Journal Article in WATER SCIENCE AND TECHNOLOGY

Enhanced removal of 1,2-dichloroethane by anodophilic microbial consortia

The PhamNico BoonMassimo MarzoratiWilly Verstraete

A1 Journal Article in WATER RESEARCH

Environmental factors shaping the ecological niches of ammonia-oxidizing archaea

Tuba H ErguderNico BoonLieven WittebolleMassimo MarzoratiWilly Verstraete

A1 Journal Article in FEMS MICROBIOLOGY REVIEWS

Initial community evenness favours functionality under selective stress

Lieven WittebolleMassimo MarzoratiLieven ClementAnnalisa BalloiDaniele DaffonchioKim HeylenPaul De VosWilly VerstraeteNico Boon

A1 Journal Article in NATURE

The intestinal environment in health and disease: recent insights on the potential of intestinal bacteria to influence human health

Sam PossemiersCharlotte GrootaertJoan VermeirenGabriele GrossMassimo MarzoratiWilly VerstraeteTom Van de Wiele

A1 Journal Article in CURRENT PHARMACEUTICAL DESIGN

2008

Dietary inclusion of wheat bran arabinoxylooligosaccharides induces beneficial nutritional effects in chickens

Christophe M CourtinWillem F BroekaertKatrien SwennenOlivier LescroartOkanlawon OnagbesanJohan BuyseEddy DecuypereTom Van de WieleMassimo MarzoratiWilly Verstraete et al.

A1 Journal Article in CEREAL CHEMISTRY

How to get more out of molecular fingerprints: practical tools for microbial ecology

Massimo MarzoratiLieven WittebolleNico BoonDaniele DaffonchioWilly Verstraete

A1 Journal Article in ENVIRONMENTAL MICROBIOLOGY

Inhibition of sulfide generation by dosing formaldehyde and its derivatives in sewage under anaerobic conditions

Lehua ZhangL MendozaMassimo MarzoratiWilly Verstraete

A1 Journal Article in WATER SCIENCE AND TECHNOLOGY

Loading rate and external resistance control the electricity generation of microbial fuel cells with different three-dimensional anodes

Peter AeltermanMathias VersicheleMassimo MarzoratiNico BoonWilly Verstraete

A1 Journal Article in BIORESOURCE TECHNOLOGY

Structurally different wheat-derived arabinoxylooligosaccharides have different prebiotic and fermentation properties in rats

Valerie Van CraeyveldKatrien SwennenEmmie DornezTom Van de WieleMassimo MarzoratiWilly VerstraeteYasmine DelaedtOkanlawon OnagbesanEddy DecuypereJohan Buyse et al.

A1 Journal Article in JOURNAL OF NUTRITION

2007

A novel reductive dehalogenase, identified in a contaminated groundwater enrichment culture and in Desulfitobacterium dichloroeliminans strain DCA1 is linked to dehalogenation of 1,2-dichloroethane

Massimo MarzoratiF DE FERRAHilde Van RaemdonckS BORINE ALLIFRANCHINIG CARPANIL SERBOLISCAWilly VerstraeteNico BoonD DAFFONCHIO

A1 Journal Article in APPLIED AND ENVIRONMENTAL MICROBIOLOGY