Research Explorer

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Researcher

Marthe Vandeputte

Awards & Distinctions

27 Results

2025

A Fentanyl Hapten-Displaying Lipid Nanoparticle Vaccine that Non-Covalently Encapsulates a TLR7/8 Agonist and T-Helper Epitope Induces Protective Anti-Fentanyl Immunity

Zifu ZhongMarie DeventerYong ChenStijn VanheeInés LammensKim DeswarteYi HuangTingting YeHaixiu WangLutz Nuhn et al.

U Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

2024

Characterization of novel nitazene recreational drugs: Insights into their risk potential from in vitro μ-opioid receptor assays and in vivo behavioral studies in mice

Marthe VandeputteGrant C. GlatfelterDonna WaltherNathan K. LayleDanielle M. St. GermaineIstván UjváryDonna M. IulaMichael H. BaumannChristophe Stove

A1 Journal Article in PHARMACOLOGICAL RESEARCH

Detection of N-desethyl etonitazene in a drug checking sample : chemical analysis and pharmacological characterization of a recent member of the 2-benzylbenzimidazole 'nitazene' class

Manuela C. MontiLiam De VriezeMarthe VandeputteMattias PerssonHenrik GreenChristophe StoveGotz Schlotterbeck

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Elucidating the harm potential of brorphine analogues as new synthetic opioids : synthesis in vitro, and in vivo characterization

Marthe VandeputteSabrine BilelMicaela TirriGiorgia CorliMarta BassiNathan K. LayleAnna FantinatiDonna WaltherDonna M. IulaMichael H. Baumann et al.

A1 Journal Article in NEUROPHARMACOLOGY

In vitro structure-activity relationships and forensic case series of emerging 2-benzylbenzimidazole 'nitazene' opioids

Liam De VriezeSara E. WaltonEline PottieDonna PapsunBarry K. LoganAlex J. KrotulskiChristophe StoveMarthe Vandeputte

A1 Journal Article in ARCHIVES OF TOXICOLOGY

In vitro μ-opioid receptor activation potential of U10 and β-U10, positional isomers of the synthetic opioid naphthyl U-47700

Marthe VandeputteChristophe Stove

A1 Journal Article in DRUG TESTING AND ANALYSIS

Nitazene test strips : a laboratory evaluation

Liam De VriezeChristophe StoveMarthe Vandeputte

A1 Journal Article in HARM REDUCTION JOURNAL

Pharmacological effects of 2-benzylbenzimidazole opioids emerging in clandestine drug markets worldwide

Michael BaumannDonna WaltherMeng-Hua TsaiLi ChenMarthe VandeputteChristophe StoveLei ShiGrant Glatfelter

The old, the new, the (un)expected : a pharmacological perspective on new synthetic opioids of the post-fentanyl analogue era

Marthe VandeputteChristophe Stove

When a prophecy comes true : ethyleneoxynitazene as a 'prophetic' member of the emerging class of 2-benzylbenzimidazole 'nitazene' synthetic opioids

Marthe VandeputteGrant GlatfelterDonna WaltherIstván UjváryDonna IulaMichael BaumannChristophe Stove

2023

Alkoxy chain length governs the potency of 2-benzylbenzimidazole nitazene' opioids associated with human overdose

Grant C. GlatfelterMarthe VandeputteLi ChenDonna WaltherMeng-Hua M. TsaiLei ShiChristophe StoveMichael H. Baumann

A1 Journal Article in PSYCHOPHARMACOLOGY

Comparative neuropharmacology of structurally distinct non-fentanyl opioids that are appearing on recreational drug markets worldwide

Marthe VandeputteMeng-Hua M. TsaiLi ChenGrant C. GlatfelterDonna WaltherChristophe StoveLei ShiMichael H. Baumann

A1 Journal Article in DRUG AND ALCOHOL DEPENDENCE

Detection, chemical analysis, and pharmacological characterization of dipyanone and other new synthetic opioids related to prescription drugs

Marthe VandeputteSara E. WaltonSarah A. ShudaDonna M. PapsunAlex J. KrotulskiChristophe Stove

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY

2022

Characterization of recent non-fentanyl synthetic opioids via three different in vitro mu-opioid receptor activation assays

Marthe VandeputteMattias PerssonDonna WaltherSvante VikingssonRobert KronstrandMichael H. BaumannHenrik GreenChristophe Stove

A1 Journal Article in ARCHIVES OF TOXICOLOGY

First identification, chemical analysis and pharmacological characterization of N-piperidinyl etonitazene (etonitazepipne), a recent addition to the 2-benzylbenzimidazole opioid subclass

Marthe VandeputteNick VerougstraeteDonna WaltherGrant C. GlatfelterJeroen MalflietMichael H. BaumannAlain VerstraeteChristophe Stove

A1 Journal Article in ARCHIVES OF TOXICOLOGY

In vitro functional assays as a tool to study new synthetic opioids at the mu-opioid receptor : potential, pitfalls and progress

Marthe VandeputteLakshmi VasudevanChristophe Stove

A1 Journal Article in PHARMACOLOGY & THERAPEUTICS

Pharmacological evaluation and forensic case series of N-pyrrolidino etonitazene (etonitazepyne), a newly emerging 2-benzylbenzimidazole 'nitazene' synthetic opioid

Marthe VandeputteAlex J. KrotulskiDonna WaltherGrant C. GlatfelterDonna PapsunSara E. WaltonBarry K. LoganMichael H. BaumannChristophe Stove

A1 Journal Article in ARCHIVES OF TOXICOLOGY

Phenethyl-4-ANPP : a marginally active byproduct suggesting a switch in illicit fentanyl synthesis routes

Marthe VandeputteAlex J. KrotulskiFabian HulpiaSerge Van CalenberghChristophe Stove

A1 Journal Article in JOURNAL OF ANALYTICAL TOXICOLOGY

The rise and fall of isotonitazene and brorphine : two recent stars in the synthetic opioid firmament

Marthe VandeputteAlex J. KrotulskiDonna M. PapsunBarry K. LoganChristophe Stove

A1 Journal Article in JOURNAL OF ANALYTICAL TOXICOLOGY

Toxicological and pharmacological characterization of novel cinnamylpiperazine synthetic opioids in humans and in vitro including 2-methyl AP-237 and AP-238

Melissa F. FogartyMarthe VandeputteAlex J. KrotulskiDonna PapsunSara E. WaltonChristophe StoveBarry K. Logan

A1 Journal Article in ARCHIVES OF TOXICOLOGY

2021

Synthesis, chemical characterization, and mu-opioid receptor activity assessment of the emerging group of 'nitazene' 2-benzylbenzimidazole synthetic opioids

Marthe VandeputteKatleen Van UytfangheNathan LayleDanielle St GermaineDonna IulaChristophe Stove

A1 Journal Article in ACS CHEMICAL NEUROSCIENCE

Systematic evaluation of a panel of 30 synthetic cannabinoid receptor agonists structurally related to MMB-4en-PICA, MDMB-4en-PINACA, ADB-4en-PINACA, and MMB-4CN-BUTINACA using a combination of binding and different CB1 receptor activation assays : part III : The G protein pathway and critical comparison of different assays

Katharina Elisabeth GrafingerMarthe VandeputteAnnelies CannaertAdam AmetovskiEric SparkesElizabeth CairnsPatrick Osamu JuchliBelal HaschimiBenedikt PulverSamuel D. Banister et al.

A1 Journal Article in DRUG TESTING AND ANALYSIS

2020

Assessment of structure-activity relationships and biased agonism at the Mu opioid receptor of novel synthetic opioids using a novel, stable bio-assay platform

Lakshmi VasudevanMarthe VandeputteMarie DeventerElise WoutersAnnelies CannaertChristophe Stove

A1 Journal Article in BIOCHEMICAL PHARMACOLOGY

First report on brorphine : the next opioid on the deadly new psychoactive substance horizon?

Nick VerougstraeteMarthe VandeputteCathelijne LyphoutAnnelies CannaertFabian HulpiaSerge Van CalenberghAlain VerstraeteChristophe Stove

A1 Journal Article in JOURNAL OF ANALYTICAL TOXICOLOGY

In vitro functional characterization of a panel of non-fentanyl opioid new psychoactive substances

Marthe VandeputteAnnelies CannaertChristophe Stove

A1 Journal Article in ARCHIVES OF TOXICOLOGY

2019

Activity-based reporter assays for the screening of abused substances in biological matrices

Annelies CannaertMarthe VandeputteSarah WilleChristophe Stove

A1 Journal Article in CRITICAL REVIEWS IN TOXICOLOGY

Validation of activity-based screening for synthetic cannabinoid receptor agonists in a large set of serum samples

Annelies CannaertMarthe VandeputteSimon HudsonDavid M WoodPaul I DarganChristophe Stove

A1 Journal Article in CLINICAL CHEMISTRY