Research Explorer

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Researcher

Marlies Ballegeer

Awards & Distinctions

29 Results

2024

A neutralizing single-domain antibody that targets the trimer interface of the human metapneumovirus fusion protein

Marlies BallegeerRevina C. van ScherpenzeelTeresa DelgadoMaria Iglesias-CaballeroBlanca García BarrenoShubham PandeyScott A. RushJoost A. KolkmanVicente MasJason S. McLellan et al.

A1 Journal Article in MBIO

Nanoparticle display of neuraminidase elicits enhanced antibody responses and protection against influenza A virus challenge

M. N. PaschaMarlies BallegeerM. C. RoelofsLeander MeurisI. C. AlbulescuF. J. M. van KuppeveldD. L. HurdissB. J. BoschT. Zeev-Ben-MordehaiXavier Saelens et al.

U Journal Article in npj Vaccines

2023

Cleavage of cFLIP restrains cell death during viral infection and tissue injury and favors tissue repair

Kristel Martinez LagunasDeniz Pinar SavcigilMatea ZrilicCarlos Carvajal FraileAndrew CraxtonEmily SelfIratxe Uranga-MurilloDiego de MiguelMaykel AriasSebastian Willenborg et al.

A1 Journal Article in SCIENCE ADVANCES

Rethinking IL-1 antagonism in respiratory viral infections : a role for IL-1 signaling in the development of antiviral T cell immunity

Bram Van Den EeckhoutMarlies BallegeerJozefien De ClercqElianne BurgXavier SaelensLinos VandekerckhoveSarah Gerlo

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

2022

ADP-ribosylating adjuvant reveals plasticity in cDC1 cells that drive mucosal Th17 cell development and protection against influenza virus infection

Mohammad ArabpourCristina Lebrero-FernandezKarin SchönAnneli StrömbergVanja BörjessonKatharina LahlMarlies BallegeerXavier SaelensDavide AngelettiWilliam Agace et al.

A1 Journal Article in MUCOSAL IMMUNOLOGY

Single domain antibodies to probe the antiviral function of human MxA

Eline SoetensXavier SaelensMarlies Ballegeer

2021

A vulnerable, membrane-proximal site in human respiratory syncytial virus F revealed by a prefusion-specific single-domain antibody

Iebe RosseyChing-Lin HsiehKoen SedeynMarlies BallegeerBert SchepensJason S. McLellanXavier Saelens

A1 Journal Article in JOURNAL OF VIROLOGY

In vivo therapy with M2e-specific IgG selects for an influenza A virus mutant with delayed matrix protein 2 expression

Silvie Van den HoeckeMarlies BallegeerBram VranckenLei DengEmma JobKenny RooseBert SchepensLien Van HoeckePhilippe LemeyXavier Saelens

A1 Journal Article in MBIO

Influenza neuraminidase characteristics and potential as a vaccine target

Sarah CreytensMirte N. PaschaMarlies BallegeerXavier SaelensCornelis A. M. de Haan

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2020

An inside job : applications of intracellular single domain antibodies

Eline SoetensMarlies BallegeerXavier Saelens

A1 Journal Article in BIOMOLECULES

Cell-mediated responses to human metapneumovirus infection

Marlies BallegeerXavier Saelens

A1 Journal Article in VIRUSES-BASEL

Glucocorticoids limit lipopolysaccharide-induced lethal inflammation by a double control system

Kelly Van LooverenSteven TimmermansTineke VanderhaeghenCharlotte WallaeysMarlies BallegeerJolien SouffriauMelanie EggermontJolien VandewalleLise Van WyngeneKarolien De Bosscher et al.

A1 Journal Article in EMBO REPORTS

The opposing effect of type I IFN on the T cell response by non-modified mRNA-lipoplex vaccines Is determined by the route of administration

Lien Van HoeckeKenny RooseMarlies BallegeerZifu ZhongNiek SandersStefaan De KokerXavier SaelensSandra Van Lint

A1 Journal Article in MOLECULAR THERAPY-NUCLEIC ACIDS

Zinc inhibits lethal inflammatory shock by preventing microbe-induced interferon signature in intestinal epithelium

Jolien SouffriauSteven TimmermansTineke VanderhaeghenCharlotte WallaeysKelly Van LooverenLindsy AelbrechtSylviane DewaeleJolien VandewalleEvy GoossensSerge Verbanck et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

2019

Overexpression of Gilz protects mice against lethal septic peritonitis

Marlies BallegeerJolien VandewalleMelanie EggermontGert Van IsterdaelLien DejagerLiesbet De BusJohan DecruyenaereRoosmarijn VandenbrouckeClaude Libert

A1 Journal Article in SHOCK

Selective engagement of FcγRIV by a M2e-specific single domain antibody construct protects against influenza A virus infection

Dorien De VliegerKatja HoffmannInge Van MolleWim NerinckxLien Van HoeckeMarlies BallegeerSarah CreytensHan RemautHartmut HengelBert Schepens et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile

Karen DendonckerSteven TimmermansJolien VandewalleMelanie EggermontJoanna LempiäinenVille PaakinahoEvelien Van HammeSylviane DewaeleSofie VandevyverMarlies Ballegeer et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2018

Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice

Marlies BallegeerKelly Van LooverenSteven TimmermansMelanie EggermontSofie VandevyverFabien Henri TheryKaren DendonckerJolien SouffriauJolien VandewalleLise Van Wyngene et al.

A1 Journal Article in JOURNAL OF CLINICAL INVESTIGATION

Simultaneous inhibition of tumor necrosis factor receptor 1 and matrix metalloproteinase 8 completely protects against acute inflammation and sepsis

Sophie SteelandSara Van RyckeghemJolien VandewalleMarlies BallegeerElien Van WonterghemMelanie EggermontJohan DecruyenaereLiesbet De BusClaude LibertRoosmarijn Vandenbroucke

A1 Journal Article in CRITICAL CARE MEDICINE

Single-domain antibodies and their formatting to combat viral infections

Dorien De VliegerMarlies BallegeerIebe RosseyBert SchepensXavier Saelens

A2 Journal Article in ANTIBODIES

2017

Glucocorticoid receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor

Ioanna PettaNadia BougarneJolien VandewalleLien DejagerSofie VandevyverMarlies BallegeerSofie DesmetJonathan ThommisLode De CauwerSam Lievens et al.

A1 Journal Article in SCIENTIFIC REPORTS

2016

Overexpression of glucocorticoid-induced leucine zipper (GILZ) increases susceptibility to imiquimod-induced psoriasis and involves cutaneous activation of TGF-β1

Elena CarcellerMarlies BallegeerJulie DeckersCarlo RiccardiStefano BruscoliTino HochepiedClaude LibertPaloma Perez

A1 Journal Article in SCIENTIFIC REPORTS

Study of the role and regulation of glucocorticoid induced leucine zipper (GILZ) and GR dimers in acute inflammation

Marlies BallegeerClaude LibertRoosmarijn Vandenbroucke

The interactome of the glucocorticoid receptor and its influence on the actions of glucocorticoids in combatting inflammatory and infectious diseases

Ioanna PettaLien DejagerMarlies BallegeerSam LievensJan TavernierKarolien De BosscherClaude Libert

A2 Journal Article in MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Topical imiquimod yields systemic effects due to unintended oral uptake

Lynda GrineSophie SteelandSara Van RyckeghemMarlies BallegeerStefan LienenklausSiegfried WeissNiek SandersRoosmarijn VandenbrouckeClaude Libert

A1 Journal Article in SCIENTIFIC REPORTS

2015

Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation

Lien DejagerKaren DendonckerMelanie EggermontJolien SouffriauFilip Van HauwermeirenMonique WillartElien Van WonterghemThomas NaessensMarlies BallegeerSofie Vandevyver et al.

A1 Journal Article in MUCOSAL IMMUNOLOGY

Predominant contribution of cis-regulatory divergence in the evolution of mouse alternative splicing

Qingsong GaoWei SunMarlies BallegeerClaude LibertWei Chen

A1 Journal Article in MOLECULAR SYSTEMS BIOLOGY

2014

Pharmacological inhibition of type I interferon signaling protects mice against lethal sepsis

Lien DejagerSofie VandevyverMarlies BallegeerElien Van WonterghemLing-Ling AnJeffrey RiggsRoland KolbeckClaude Libert

A1 Journal Article in JOURNAL OF INFECTIOUS DISEASES

2013

LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by the Tsc22d3 gene on the X chromosome

Iris PinheiroLien DejagerIoanna PettaSofie VandevyverLeen PuimègeTina MahieuMarlies BallegeerFilip Van HauwermeirenCarlo RiccardiMarnik Vuylsteke et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE