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Researcher
Marleen Van Troys
Profile
Projects
Publications
Activities
Awards & Distinctions
75
Results
2023
Multisite assessment of reproducibility in high‐content cell migration imaging data
Jianjiang Hu
Xavier Serra‐Picamal
Gert‐Jan Bakker
Marleen Van Troys
Sabina Winograd‐Katz
Nil Ege
Xiaowei Gong
Yuliia Didan
Inna Grosheva
Omer Polansky
et al.
A1
Journal Article
in
MOLECULAR SYSTEMS BIOLOGY
2023
2022
Innovative mouse models for the tumor suppressor activity of protocadherin-10 isoforms
Irene Kleinberger
Ellen Sanders
Katrien Staes
Marleen Van Troys
Shinji Hirano
Tino Hochepied
Kelly Lemeire
Liesbet Martens
Christophe Ampe
Frans Van Roy
A1
Journal Article
in
BMC CANCER
2022
2021
Cancer type-specific alterations in actin genes : worth a closer look?
Christophe Ampe
Laura Witjes
Marleen Van Troys
Bookchapter
in
Actin cytoskeleton in cancer progression and metastasis : part C
2021
Furan warheads for covalent trapping of weak protein-protein interactions : cross-linking of thymosin β4 to actin
Laia Miret Casals
Willem Vannecke
Kurt Hoogewijs
Gianluca Arauz-Garofalo
Marina Gay
Mireia Diaz-Lobo
Marta Vilaseca
Christophe Ampe
Marleen Van Troys
Annemieke Madder
A1
Journal Article
in
CHEMICAL COMMUNICATIONS
2021
Pseudomonas cyclic lipopeptides as cytotoxic agents for cancer cells : structure-function analysis
Yentl Verleysen
José Martins
Annemieke Madder
Marleen Van Troys
Dissertation
2021
2020
Dry heat induced whey protein-lactose conjugates largely improve the heat stability of O/W emulsions
Qurrotul A'yun
Paolo Demicheli
Lorenz De Neve
Jianfeng Wu
Mathieu Balcaen
Arima Diah Setiowati
José Martins
Marleen Van Troys
Paul Van der Meeren
A1
Journal Article
in
INTERNATIONAL DAIRY JOURNAL
2020
Heat stable whey protein stabilised O/W emulsions : optimisation of the whey protein concentrate dry heat incubation conditions
Qurrotul A'yun
Istna Nafi Azzahrani
Arne Huyst
Lorenz De Neve
José Martins
Marleen Van Troys
Chusnul Hidayat
Paul Van der Meeren
A1
Journal Article
in
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
2020
Maillard conjugation of whey protein isolate with water-soluble fraction of almond gum or flaxseed mucilage by dry heat treatment
Ali Sedaghat Doost
Maryam Nikbakht Nasrabadi
Sayed Amir Hossein Goli
Marleen Van Troys
Peter Dubruel
Nympha De Neve
Paul Van der Meeren
A1
Journal Article
in
FOOD RESEARCH INTERNATIONAL
2020
Prevalence of cytoplasmic actin mutations in diffuse large B-cell lymphoma and multiple myeloma : a functional assessment based on actin three-dimensional structures
Laura Witjes
Marleen Van Troys
Bruno Verhasselt
Christophe Ampe
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2020
2019
A new evolutionary model for the vertebrate actin family including two novel groups
Laura Witjes
Marleen Van Troys
Joël Vandekerckhove
Klaas Vandepoele
Christophe Ampe
A1
Journal Article
in
MOLECULAR PHYLOGENETICS AND EVOLUTION
2019
DoRes within CellMissy : dose-response analysis on cell migration and related data
Gwendolien Sergeant
Lennart Martens
Marleen Van Troys
Paola Masuzzo
A1
Journal Article
in
BIOINFORMATICS
2019
2018
Analysis of invasion dynamics of matrix-embedded cells in a multisample format
Marleen Van Troys
Paola Masuzzo
Lynn Huyck
Karima Bakkali
Davy Waterschoot
Lennart Martens
Christophe Ampe
Bookchapter
in
Cell migration : methods and protocols
2018
Combination of EGFR inhibitor lapatinib and MET inhibitor foretinib inhibits migration of triple negative breast cancer cell lines
Aleksandra Simiczyjew
Ewelina Dratkiewicz
Marleen Van Troys
Christophe Ampe
Ilona Styczeń
Dorota Nowak
A1
Journal Article
in
CANCERS
2018
Concerted biophysical and biological evaluation of Pseudomonas lipopeptides as a premise to unlock their application potential
José Martins
Yentl Verleysen
Benjámin Kovács
Vic De Roo
Christophe Ampe
Annemieke Madder
Marleen Van Troys
Niels Geudens
C3
Conference
2018
Exploration of CLP antitumor potential
Yentl Verleysen
Matthias De Vleeschouwer
Niels Geudens
Marleen Van Troys
Christophe Ampe
Annemieke Madder
José Martins
C3
Conference
2018
Influence of CLP structure on antitumor potential
Yentl Verleysen
Matthias De Vleeschouwer
Niels Geudens
Tim Van Kersavond
Arend Mandelings
Marleen Van Troys
Christophe Ampe
Annemieke Madder
José Martins
C3
Conference
2018
Surveillance of myelodysplastic syndrome via migration analyses of blood neutrophils : a potential prognostic tool
Marc Schuster
Mischa Moeller
Lea Bornemann
Clara Bessen
Charlyn Sobczak
Saskia Schmitz
Laura Witjes
Katja Kruithoff
Christina Kohn
Olga Just
et al.
A1
Journal Article
in
JOURNAL OF IMMUNOLOGY
2018
2017
An end-to-end software solution for the analysis of high-throughput single-cell migration data
Paola Masuzzo
Lynn Huyck
Aleksandra Simiczyjew
Christophe Ampe
Lennart Martens
Marleen Van Troys
A1
Journal Article
in
SCIENTIFIC REPORTS
2017
Cross-linking furan-modified kisspeptin-10 to the KISS receptor
Willem Vannecke
Christophe Ampe
Marleen Van Troys
Massimiliano Beltramo
Annemieke Madder
A1
Journal Article
in
ACS CHEMICAL BIOLOGY
2017
Expanding the interactome of TES by exploiting TES modules with different subcellular localizations
Stefano Sala
Marleen Van Troys
Sandrine Medves
Marie Catillon
Evy Timmerman
An Staes
Elisabeth Schaffner-Reckinger
Kris Gevaert
Christophe Ampe
A1
Journal Article
in
JOURNAL OF PROTEOME RESEARCH
2017
Inhibitory cortactin nanobodies delineate the role of NTA- and SH3-domain-specific functions during invadopodium formation and cancer cell invasion
Laurence Bertier
Ciska Boucherie
Olivier Zwaenepoel
Berlinda Vanloo
Marleen Van Troys
Isabel Van Audenhove
Jan Gettemans
A1
Journal Article
in
FASEB JOURNAL
2017
Structure-function study of the focal adhesion protein and tumour suppressor testin : determination of module-specific interactomes and expansion of its conformational repertoire
Stefano Sala
Christophe Ampe
Marleen Van Troys
Dissertation
2017
The PET and LIM1-2 domains of testin contribute to intramolecular and homodimeric interactions
Stefano Sala
Marie Catillon
Ermin Hadzic
Elisabeth Schaffner-Reckinger
Marleen Van Troys
Christophe Ampe
A1
Journal Article
in
PLOS ONE
2017
2016
An actomyosin-like cytoskeleton in the cyanobiont (Nosctoc sp.) of Peltigera canina
Eva-María Diaz
Christophe Ampe
Marleen Van Troys
Miguel Vicente-Manzanares
María-Estrella Legaz
Carlos Vicente
A1
Journal Article
in
PHYTOCHEMISTRY LETTERS
2016
Furan-based crosslinking in situ : seizing ligand-receptor complexes in the act
Willem Vannecke
Christophe Ampe
Marleen Van Troys
Annemieke Madder
C3
Conference
2016
Mammalian actins : isoform-specific functions and diseases
Christophe Ampe
Marleen Van Troys
Bookchapter
in
The actin cytoskeleton
2016
Quantitative evaluation of single cell spread on collagen matrices
Elly De Vlieghere
Glenn Wagemans
S De Backer
Zuzanna Drebert
Joke Tommelein
Quentin Rousseau
B Weyn
Marleen Van Troys
Marc Bracke
Olivier De Wever
A1
Journal Article
in
EXPERIMENTAL CELL RESEARCH
2016
Taking aim at moving targets in computational cell migration
Paola Masuzzo
Marleen Van Troys
Christophe Ampe
Lennart Martens
A1
Journal Article
in
TRENDS IN CELL BIOLOGY
2016
The unfolded protein response underlies microenvironmental stress-induced phenotype switching leading to stemness and chemoresistance in human hepatocellular carcinoma
Yves-Paul Vandewynckel
O Govaere
Aster Vandierendonck
Debby Laukens
Lindsey Devisscher
Annelies Paridaens
Eliene Bogaerts
Sarah Raevens
Xavier Verhelst
Christophe Van Steenkiste
et al.
C3
Conference
2016
Towards an open data exchange ecosystem : forging a new path for cell migration data analysis and mining
Paola Masuzzo
Christophe Ampe
Lennart Martens
Marleen Van Troys
Dissertation
2016
2015
Active invadopodia of mesenchymally migrating cancer cells contain both β and γ cytoplasmic actin isoforms
Aleksandra Simiczyjew
Antonina Joanna Mazur
Christophe Ampe
Maria Malicka-Błaszkiewicz
Marleen Van Troys
Dorota Nowak
A1
Journal Article
in
EXPERIMENTAL CELL RESEARCH
2015
An open data ecosystem for cell migration research
Paola Masuzzo
Lennart Martens
the 2014 Cell Migration workshop participants
Christophe Ampe
Olivier De Wever
Marleen Van Troys
Editorial material
2015
Delineating the Tes interaction site in zyxin and studying cellular effects of its disruption
Ermin Hadzic
Marle Catillon
Allaksandr Halavatyi
Sandrine Medves
Marleen Van Troys
Michèle Moes
Michelle A Baird
Michael W Davidson
Elisabeth Schaffner-Reckinger
Christophe Ampe
et al.
A1
Journal Article
in
PLOS ONE
2015
Pseudorabies virus US3 triggers RhoA phosphorylation to reorganize the actin cytoskeleton
Thary Jacob
Celine Van den Broeke
Cliff Van Waesberghe
Marleen Van Troys
Herman Favoreel
A1
Journal Article
in
JOURNAL OF GENERAL VIROLOGY
2015
Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure
Yves-Paul Vandewynckel
Debby Laukens
Lindsey Devisscher
Annelies Paridaens
Eliene Bogaerts
Xavier Verhelst
A Van den Bussche
Sarah Raevens
Christophe Van Steenkiste
Marleen Van Troys
et al.
C3
Conference
2015
Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure
Yves-Paul Vandewynckel
Debby Laukens
Lindsey Devisscher
Annelies Paridaens
Eliene Bogaerts
Xavier Verhelst
Anja Van den Bussche
Sarah Raevens
Christophe Van Steenkiste
Marleen Van Troys
et al.
A1
Journal Article
in
ONCOTARGET
2015
2014
β-Agonists selectively modulate proinflammatory gene expression in skeletal muscle cells via non-canonical nuclear crosstalk mechanisms
Krzysztof Kolmus
Marleen Van Troys
Karlien Van Wesemael
Christophe Ampe
Guy Haegeman
Jan Tavernier
Sarah Gerlo
A1
Journal Article
in
PLOS ONE
2014
2013
A nanobody targeting the F-actin capping protein CapG restrains breast cancer metastasis
Katrien Van Impe
Jonas Bethuyne
Steven Cool
Francis Impens
David Ruano-Gallego
Olivier De Wever
Berlinda Vanloo
Marleen Van Troys
Kathleen Lambein
Ciska Boucherie
et al.
A1
Journal Article
in
BREAST CANCER RESEARCH
2013
Alphaherpesviral US3 kinase induces cofilin dephosphorylation to reorganize the actin cytoskeleton
Thary Jacob
Celine Van den Broeke
Marleen Van Troys
Davy Waterschoot
Christophe Ampe
Herman Favoreel
A1
Journal Article
in
JOURNAL OF VIROLOGY
2013
CellMissy: a tool for management, storage and analysis of cell migration data produced in wound healing-like assays
Paola Masuzzo
Niels Hulstaert
Lynn Huyck
Christophe Ampe
Marleen Van Troys
Lennart Martens
A1
Journal Article
in
BIOINFORMATICS
2013
p210bcr-abl induces amoeboid motility by recruiting ADF/destrin through RhoA/ROCK1
Tristan Rochelle
Thomas Daubon
Marleen Van Troys
Thomas Harnois
Davy Waterschoot
Christophe Ampe
Lydia Roy
Nicolas Bourmeyster
Bruno Constantin
A1
Journal Article
in
FASEB JOURNAL
2013
β-actin knock-out mouse embryonic fibroblasts show increased expression of LIM-, CH-, EFh-domain containing proteins with predicted common upstream regulators
Christophe Ampe
Jelle Libbrecht
Marleen Van Troys
A1
Journal Article
in
CYTOSKELETON
2013
2012
Phosphosite conservation in single domain orthologs versus paralogs: a way to combine differential regulation with redundant core functions
Lynn Huyck
Marleen Van Troys
Christophe Ampe
A1
Journal Article
in
FEBS LETTERS
2012
The US3 kinase of pseudorabies virus leads to activation of the actin regulator cofilin to induce actin cytoskeleton changes
Thary Jacob
Celine Van den Broeke
Marleen Van Troys
Davy Waterschoot
Christophe Ampe
Herman Favoreel
C3
Conference
2012
The XTT cell proliferation assay applied to cell layers embedded in three-dimensional matrix
Lynn Huyck
Christophe Ampe
Marleen Van Troys
A1
Journal Article
in
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
2012
2011
A QUICK screen for Lrrk2 interaction partners: leucine-rich repeat kinase 2 is involved in actin cytoskeleton dynamics
Andrea Meixner
Karsten Boldt
Marleen Van Troys
Manor Askenazi
Chrsitian J Gloeckner
Matthias Bauer
Jarrod A Marto
Christophe Ampe
Norbert Kinkl
Marius Ueffing
A1
Journal Article
in
MOLECULAR & CELLULAR PROTEOMICS
2011
2009
An integrative simulation model linking major biochemical reactions of actin-polymerization to structural properties of actin filaments
Aliaksandr A. Halavatyi
Petr V. Nazarov
Sandrine Medves
Marleen Van Troys
Christophe Ampe
Mikalai Yatskou
Evelyne Friederich
A1
Journal Article
in
BIOPHYSICAL CHEMISTRY
2009
The Mouse Thymosin Beta15 Gene Family Displays Unique Complexity and Encodes A Functional Thymosin Repeat
Stien Dhaese
Klaas Vandepoele
Davy Waterschoot
Berlinda Vanloo
Joël Vandekerckhove
Christophe Ampe
Marleen Van Troys
A1
Journal Article
in
JOURNAL OF MOLECULAR BIOLOGY
2009
Unbalancing the phosphatidylinositol-4,5-bisphosphate-cofilin interaction impairs cell steering
Shirley Leyman
Mazen Sidani
Laila Ritsma
Davy Waterschoot
Robert Eddy
Daisy Dewitte
Olivier Debeir
Christine Decaestecker
Joël Vandekerckhove
Jacco van Rheenen
et al.
A1
Journal Article
in
MOLECULAR BIOLOGY OF THE CELL
2009
2008
Ins and outs of ADF/cofilin activity and regulation
Marleen Van Troys
Lynn Huyck
Shirley Leyman
Stien Dhaese
Joël Vandekerckhove
Christophe Ampe
A1
Journal Article
in
EUROPEAN JOURNAL OF CELL BIOLOGY
2008
Listeria comet tails: the actin-based motility machinery at work
Anja Lambrechts
Kris Gevaert
P COSSART
Joël Vandekerckhove
Marleen Van Troys
A1
Journal Article
in
TRENDS IN CELL BIOLOGY
2008
Predicting the effect of a point mutation on a protein fold: The villin and advillin headpieces and their Pro62Ala mutants
S PIANA
A LAIO
F MARINELLI
Marleen Van Troys
David Bourry
Christophe Ampe
José Martins
A1
Journal Article
in
JOURNAL OF MOLECULAR BIOLOGY
2008
The actin propulsive machinery: The proteome of Listeria monocytogenes tails
Marleen Van Troys
Anja Lambrechts
Vera David
Hans Demol
Magda Puype
J PIZARRO-CERDA
Kris Gevaert
P COSSART
Joël Vandekerckhove
A1
Journal Article
in
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
2008
2007
Atomistic Prediction of the structure of the Advillin headpiece and its Pro62Ala mutant
José Martins
A LAIO
F MARINELLI
Marleen Van Troys
Christophe Ampe
David Bourry
S PIANO
C1
Conference
2007
Functional and profiling studies prove that prostate cancer upregulated neuroblastoma thymosin beta is the true human homologue of rat thymosin beta 15
Stien Dhaese
Veronique Jonckheere
Marc Goethals
D WALTREGNY
Joël Vandekerckhove
Christophe Ampe
Marleen Van Troys
A1
Journal Article
in
FEBS LETTERS
2007
Structural and Functional Implicationof the PXWK-motif in HeadPiece Domains
David Bourry
W VERMEULEN
Marleen Van Troys
Joël Vandekerckhove
Christophe Ampe
José Martins
C1
Conference
2007
Structural and Functional Implications of the PXWK-motif in HeadPiece Domains
David Bourry
W VERMEULEN
Marleen Van Troys
Joël Vandekerckhove
Christophe Ampe
José Martins
C1
Conference
2007
Structure-function relationship of actin binding modules studied by NMR
David Bourry
Marleen Van Troys
M DUMOULIN
A MATAGNE
Christophe Ampe
José Martins
C1
Conference
2007
The LIM domains of WLIM1 define a new class of actin bundling modules
C THOMAS
F MOREAU
M DIETERLE
C HOFFMANN
S GATTI
C HOFMANN
Marleen Van Troys
Christophe Ampe
A STEINMETZ
A1
Journal Article
in
JOURNAL OF BIOLOGICAL CHEMISTRY
2007
2006
Identification of the PXW sequence as a structural gatekeeper of the headpiece C-terminal subdomain fold
Wim Vermeulen
Marleen Van Troys
David Bourry
Daisy Dewitte
Stefaan Rossenu
Marc Goethals
Frans Borremans
Joël Vandekerckhove
José Martins
Christophe Ampe
A1
Journal Article
in
JOURNAL OF MOLECULAR BIOLOGY
2006
Multirepeat beta-thymosins
Marleen Van Troys
Stien Dhaese
Joël Vandekerckhove
Christophe Ampe
Bookchapter
in
Actin-Monomer-Binding Proteins
2006
THE ROLE OF PRO62 AND TRP64 FOR HEADPIECE STABILITY
David Bourry
W VERMEULEN
Marleen Van Troys
D DEWITTE
S ROSSENU
Marc Goethals
Frans Borremans
Joël Vandekerckhove
José Martins
Christophe Ampe
C1
Conference
2006
The Role of Pro62 and Trp64 for HeadPiece Stability
David Bourry
W VERMEULEN
Marleen Van Troys
Marc Goethals
Frans Borremans
Joël Vandekerckhove
Christophe Ampe
José Martins
C1
Conference
2006
Tobacco WLIM1 is a novel F-actin binding protein involved in actin cytoskeleton remodeling
Clément Thomas
Céline Hoffmann
Monika Dieterle
Marleen Van Troys
Christophe Ampe
André Steinmetz
A1
Journal Article
in
PLANT CELL
2006
2005
Actin-filament cross-linking protein T-plastin increases Arp2/3-mediated actin-based movement
A GIGANTI
J PLASTINO
B JANJI
Marleen Van Troys
D LENTZ
Christophe Ampe
C SYKES
E FRIEDERICH
A1
Journal Article
in
JOURNAL OF CELL SCIENCE
2005
2004
Solution structures of the C-terminal headpiece subdomains of human villin and advillin, evaluation of headpiece F-actin-binding requirements
Wim Vermeulen
Peter Vanhaesebrouck
Marleen Van Troys
M VERSCHUEREN
Franky Fant
Marc Goethals
Christophe Ampe
José Martins
Frans Borremans
A1
Journal Article
in
PROTEIN SCIENCE
2004
TetraThymosin beta is required for actin dynamics in Caenorhabditis elegans and acts via functionally different actin-binding repeats
Marleen Van Troys
K ONO
Daisy Dewitte
Veronique Jonckheere
Natalie De Ruyck
Joël Vandekerckhove
S ONO
Christophe Ampe
A1
Journal Article
in
MOLECULAR BIOLOGY OF THE CELL
2004
The actin cytoskeleton in normal and pathological cell motility
Anja Lambrechts
Marleen Van Troys
Christophe Ampe
A1
Journal Article
in
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
2004
2003
A phage display-based method for determination of relative affinities of mutants - Application to the actin-binding motifs in thymosin beta 4 and the villin headpiece
S ROSSENU
Shirley Leyman
Daisy Dewitte
Danny Peelaers
Veronique Jonckheere
Marleen Van Troys
Joël Vandekerckhove
Christophe Ampe
A1
Journal Article
in
JOURNAL OF BIOLOGICAL CHEMISTRY
2003
2000
Structural requirements for thymosin beta 4 in its contact with actin - An NMR-analysis of thymosin beta 4 mutants in solution and correlation with their biological activity.
C SIMENEL
Marleen Van Troys
Joël Vandekerckhove
Christophe Ampe
M DELEPIERRE
A1
Journal Article
in
EUROPEAN JOURNAL OF BIOCHEMISTRY
2000
The competitive interaction of actin and PIP2 with actophorin is based on overlapping target sites : design of a gain-of-function mutant
Marleen Van Troys
Daisy Dewitte
Jean-Luc Verschelde
Marc Goethals
Joël Vandekerckhove
Christophe Ampe
A1
Journal Article
in
BIOCHEMISTRY
2000
1999
Structural modules in actin binding proteins: towards a new classification.
Marleen Van Troys
Joël Vandekerckhove
Christophe Ampe
A1
Journal Article
in
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
1999
1998
Structuur-functie analyse van thymosine ßb4, cofiline en gelsoline, drie actinebindende eiwitten met een sleutelrol in microfilamentendynamica
Marleen Van Troys
J. Vandekerckhove
C. Ampe
Dissertation
1998
1997
Analogous F-actin binding by cofilin and gelsolin segment 2 substantiates their structural relationship
Marleen Van Troys
Daisy Dewitte
Jean-Luc Verschelde
Mark Goethals
Joël Vandekerckhove
Christophe Ampe
A1
Journal Article
in
JOURNAL OF BIOLOGICAL CHEMISTRY
1997
1996
T beta(4) is not a simple G-actin sequestering protein and interacts with F-actin at high concentration
MF Carlier
D Didry
I Erk
J Lepault
Marleen Van Troys
Joël Vandekerckhove
I Perelroizen
H Yin
YK Doi
D Pantaloni
A1
Journal Article
in
JOURNAL OF BIOLOGICAL CHEMISTRY
1996