Research Explorer

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Researcher

Marilyn De Graeve

Awards & Distinctions

48 Results

2024

Integrated gut metabolome and microbiome fingerprinting reveals that dysbiosis precedes allergic inflammation in IgE-mediated pediatric cow's milk allergy

Ellen De PaepeVera PlekhovaPablo VangeenderhuysenNele BaeckDominique BullensTania ClaeysMarilyn De GraeveKristien KamoenAnneleen NotebaertTom Van de Wiele et al.

A1 Journal Article in ALLERGY

2023

Advancing ambient ionisation mass spectrometry towards at-line microbial fermentation monitoring

Nicolas de FoozMarilyn De GraevePablo VangeenderhuysenKarolien MaesSophie RoelantsSofie De MaeseneireWim SoetaertLynn Vanhaecke

Advancing pediatric precision healthcare : integrating rapid metabotyping as a fundamental component for 4P medicine

Kimberly De WindtMarilyn De GraeveStefaan De HenauwLynn Vanhaecke

Comprehensive metabolomics reveals correlation between sophorolipid biosynthesis and autophagy

Sven DierickxMaximilien SouvereynsSophie RoelantsMarilyn De GraeveLieven Van MeulebroekSofie De MaeseneireWim SoetaertLynn Vanhaecke

A1 Journal Article in NEW BIOTECHNOLOGY

Determining the main drivers of childhood overweight using the gastrointestinal metabolome of the deeply phenotyped OPERA cohort

Marilyn De GraeveKathleen WijnantNathalie MichelsStefaan De HenauwLynn Vanhaecke

Dual UHPLC-HRMS metabolomics and lipidomics and automated data processing workflow for comprehensive high-throughput gut phenotyping

Pablo VangeenderhuysenJasmien van ArnhemBeata PomianMarilyn De GraeveL. De CommerG. FalonyJ. RaesA. ZhernakovaJ. FuLieselot Hemeryck et al.

A1 Journal Article in ANALYTICAL CHEMISTRY

Dual UHPLC-HRMS-based fecal metabolomics and lipidomics followed by semi-automated data processing for comprehensive gut phenotyping

Pablo VangeenderhuysenBeata PomianMarilyn De GraeveLindsay De CommerGwen FalonyJeroen RaesAlexandra ZhernakovaJingyuan FuLieselot HemeryckLynn Vanhaecke

Exploration and optimization of extraction, analysis and data normalization strategies for mass spectrometry-based DNA adductome mapping and modeling

Marilyn De GraeveEmma Van de WalleThomas Van HeckeStefaan De SmetLynn VanhaeckeLieselot Hemeryck

A1 Journal Article in ANALYTICA CHIMICA ACTA

Integrated gut metabolome and microbiome fingerprinting reveals that dysbiosis precedes allergic inflammation in IgE-mediated pediatric cow’s milk allergy

Ellen De PaepeVera PlekhovaLars VereeckeMyriam Van WinckelMarilyn De GraeveTom Van de WieleEric CoxLynn Vanhaecke

Integrated gut metabolome and microbiome fingerprinting reveals that dysbiosis precedes allergic inflammation in IgE-mediated pediatric cow’s milk allergy

Ellen De PaepeVera PlekhovaPablo VangeenderhuysenLars VereeckeMyriam Van WinckelMarilyn De GraeveTom Van de WieleEric CoxLynn Vanhaecke

Metabotyping children using rectal MetaSAMP®-LA-REIMS : the MetaBEAse cohort

Margot De SpiegeleerVera PlekhovaKimberly De WindtMarilyn De GraeveJozefien GeltmeyerInge GiesStefaan De HenauwKaren De ClerckLynn Vanhaecke

Multivariate versus machine learning-based classification of rapid evaporative Ionisation mass spectrometry spectra towards industry based large-scale fish speciation

Marilyn De GraeveNicholas BirseYunhe HongChristopher T. ElliottLieselot HemeryckLynn Vanhaecke

A1 Journal Article in FOOD CHEMISTRY

Perspectives for DNA adductomics in large-scale exposomics : upscaling sample preparation and preprocessing data

Lieselot HemeryckMarilyn De GraeveThomas Van HeckeStefaan De SmetLynn Vanhaecke

Point-of-care applicable metabotyping using biofluid-specific electrospun MetaSAMPs directly amenable to ambient LA-REIMS

Margot De SpiegeleerVera PlekhovaJozefien GeltmeyerElla SchoolaertBeata PomianVaroon SinghKathleen WijnantKimberly De WindtVolter PaukkuAlexander De Loof et al.

A1 Journal Article in SCIENCE ADVANCES

Recent advances in high-throughput biofluid metabotyping by direct infusion and ambient ionization mass spectrometry

Vera PlekhovaKimberly De WindtMargot De SpiegeleerMarilyn De GraeveLynn Vanhaecke

A1 Journal Article in TRAC-TRENDS IN ANALYTICAL CHEMISTRY

T.A.R.D.I.S. : Targeted Analysis and Raw Data Integration in Mass Spectrometry

Pablo VangeenderhuysenBeata PomianMarilyn De GraeveLieselot HemeryckLynn Vanhaecke

Universal at-line microbial fermentation monitoring through advances in rapid ambient ionisation mass spectrometry-based metabolomics

Nicolas de FoozMarilyn De GraevePablo VangeenderhuysenKarolien MaesSophie RoelantsSofie De MaeseneireWim SoetaertLynn Vanhaecke

Upscaling sample preparation, analysis and data preprocessing in DNA adductomics for large-scale exposomics

Lieselot HemeryckMarilyn De GraeveThomas Van HeckeStefaan De SmetLiesa EngelenRoger Peró GascónGiulia PomaSarah De SaegerTim NawrotAdrian Covaci et al.

2022

Challenges and opportunities in translating lab research to industry for novel sophorolipids

Nicolas de FoozSophie RoelantsKarolien MaesMarilyn De GraeveLynn VanhaeckeWim Soetaert

Determining the main drivers of childhood obesity using machine learning-based gut metabolome prediction

Marilyn De GraeveKathleen WijnantNathalie MichelsStefaan De HenauwLynn Vanhaecke

Discovery and structure elucidation of novel alkaloids from marine actinobacteria

Jeltien RombautAnne-Sofie De RopThomas WillemsMarilyn De GraeveLynn VanhaeckePaco HulpiauSofie De MaeseneireMaarten De MolWim Soetaert

Electrospun nanofibrous samplers (MetaSAMP) provide superior biofluid metabolome stability and coverage following direct laser-assisted rapid evaporative ionization mass spectrometry

Vera PlekhovaMargot De SpiegeleerJozefien GeltmeyerBeata PomianVaroon SinghEllen De PaepeKathleen WijnantInge GiesNathalie MichelsMarilyn De Graeve et al.

Integrating gut metabolomics and microbiomics towards biomarker discovery in pediatric cow’s milk allergy

Pablo VangeenderhuysenEllen De PaepeLieselot HemeryckMarilyn De GraeveLynn Vanhaecke

Integrating gut metabolomics and microbiomics towards biomarker discovery in pediatric cow’s milk allergy

Pablo VangeenderhuysenEllen De PaepeLieselot HemeryckMarilyn De GraeveLynn Vanhaecke

Metabolome alterations in a mouse model support microbiome-metabolite interactions in a cohort of children with cow's milk allergy

Ellen De PaepeVera PlekhovaLars VereeckeMyriam Van WinckelMarilyn De GraeveTom Van de WieleEric CoxLynn Vanhaecke

Metabolome alterations in a mouse model support microbiome-metabolite interactions in a cohort of children with cow's milk allergy

Ellen De PaepeVera PlekhovaLars VereeckeMyriam Van WinckelMarilyn De GraeveTom Van de WieleEric CoxLynn Vanhaecke

Metabolome alterations in a mouse model support microbiome-metabolite interactions in a cohort of children with cow's milk allergy

Ellen De PaepeVera PlekhovaLars VereeckeMyriam Van WinckelMarilyn De GraeveEric CoxLynn Vanhaecke

Metabolome alterations in a mouse model support microbiome-metabolite interactions in a cohort of children with cow’s milk allergy

Ellen De PaepeVera PlekhovaLars VereeckeMyriam Van WinckelMarilyn De GraeveTom Van de WieleEric CoxLynn Vanhaecke

Multi-omics data integration in pediatric cow’s milk allergy using DIABLO

Pablo VangeenderhuysenEllen De PaepeLieselot HemeryckMarilyn De GraeveLynn Vanhaecke

Sophorolipid production in Starmerella bombicola under different nitrogen conditions

Nicolas de FoozSophie RoelantsMarilyn De GraeveKarolien MaesLynn VanhaeckeWim Soetaert

Towards a mouse model for studying food allergies from a metabolomics perspective : the case of pediatric cow’s milk allergy

Ellen De PaepeVera PlekhovaLars VereeckeMyriam Van WinckelMarilyn De GraeveEric CoxLynn Vanhaecke

2021

Novel alkaloids from marine actinobacteria : discovery and characterization

Anne-Sofie De RopJeltien RombautThomas WillemsMarilyn De GraeveLynn VanhaeckePaco HulpiauSofie De MaeseneireMaarten De MolWim Soetaert

A1 Journal Article in MARINE DRUGS

Palmitic acid sophorolipid biosurfactant : from self-assembled fibrillar network (SAFiN) to hydrogels with fast recovery

Niki BaccileGhazi Ben MessaoudPatrick Le GrielNathan CowiesonJavier PerezRobin GeysMarilyn De GraeveSophie RoelantsWim Soetaert

A1 Journal Article in PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Rapid ex vivo molecular fingerprinting of biofluids using laser-assisted rapid evaporative ionization mass spectrometry

Vera PlekhovaLieven Van MeulebroekMarilyn De GraeveAlvaro Perdones-MonteroMargot De SpiegeleerEllen De PaepeEmma Van de WalleZoltan TakatsSimon J. S. CameronLynn Vanhaecke

A1 Journal Article in NATURE PROTOCOLS

Real-time data acquisition and species prediction using REIMS and supervised machine learning to combat fish fraud in an industrial setting

Marilyn De GraeveNicholas BirseChristopher ElliottLynn Vanhaecke

2020

Exploration of LC-MS approaches for DNA adductome mapping and modeling

Emma Van de WalleRomel P. DatorValeria GuidolinMarilyn De GraevePeter W. VillaltaLynn VanhaeckeSilvia BalboLieselot Hemeryck

Fermentomics : a real-time metabolomics approach for the enhanced production of biosurfactants

Nicolas de FoozSophie RoelantsMarilyn De GraeveLynn VanhaeckeWim Soetaert

Hyperparameter optimization of metabolomics datasets and the impact thereof on supervised modeling outcomes

Marilyn De GraeveLynn Vanhaecke

Impact of storage conditions on the human stool metabolome and lipidome : preserving the most accurate fingerprint

Margot De SpiegeleerMarilyn De GraeveSteve HuysmanArno VanderbekeLieven Van MeulebroekLynn Vanhaecke

A1 Journal Article in ANALYTICA CHIMICA ACTA

2019

Characterization of the yeast Starmerella bombicola for the improved production of lipophilic compounds

Marilyn De GraeveWim SoetaertSophie RoelantsSofie De Maeseneire

Production of long-chain hydroxy fatty acids by Starmerella bombicola

Marilyn De GraeveIsabelle Van de VeldeLien SaeyMaarten ChysHanne OortsHümeyra KahrimanStein MinckeChristian StevensSofie De MaeseneireSophie Roelants et al.

A1 Journal Article in FEMS YEAST RESEARCH

2018

Increasing uniformity of biosurfactant production in Starmerella bombicola via the expression of chimeric cytochrome P450s

Robin GeysMarilyn De GraeveSofie LodensJeroen Van MalderenChristophe LemmensMargaux De SmetStein MinckeInge Van BogaertChristian StevensSofie De Maeseneire et al.

A2 Journal Article in COLLOIDS AND INTERFACES

Starmerella bombicola, an industrially relevant, yet fundamentally underexplored yeast

Marilyn De GraeveSofie De MaeseneireSophie RoelantsWim Soetaert

A1 Journal Article in FEMS YEAST RESEARCH

Transformation of an exotic yeast species into a platform organism : a case study for engineering glycolipid production in the yeast Starmerella bombicola

Sofie LodensMarilyn De GraeveSophie RoelantsSofie De MaeseneireWim Soetaert

Bookchapter in Synthetic biology : methods and protocols

2017

Comparative lipid analysis of the bio-surfactants producing yeast Starmerella bombicola

Marilyn De GraeveSophie RoelantsSofie De MaeseneireInge Van BogaertWim Soetaert

Development of an autonomous replicating plasmid for Starmerella bombicola

Marilyn De GraeveSophie RoelantsSofie De MaeseneireWim Soetaert

2015

Lipid analysis: a way to improve the production of sophorolipids by Starmerella bombicola

Marilyn De GraeveInge Van BogaertWim Soetaert

Lipidomics for the production of biosurfactants

Marilyn De GraeveInge Van BogaertWim Soetaert