Research Explorer

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Researcher

Marie-Gabrielle Goossens

Awards & Distinctions

38 Results

2022

Chemogenetic seizure control with clozapine and the novel ligand JHU37160 outperforms the effects of Levetiracetam in the intrahippocampal kainic acid mouse model

Jana DeslooverePaul BoonLars Emil LarsenMarie-Gabrielle GoossensJean DelbekeEvelien CarretteWytse WadmanKristl VonckRobrecht Raedt

A1 Journal Article in NEUROTHERAPEUTICS

Chemogenetic seizure control with clozapine and the novel ligand JHU37160 outperforms the effects of levetiracetam in the intrahippocampal kainic acid mouse model

Jana DeslooverePaul BoonLars Emil LarsenMarie-Gabrielle GoossensJean DelbekeEvelien CarretteWytse WadmanKristl VonckRobrecht Raedt

A1 Journal Article in NEUROTHERAPEUTICS

White matter integrity in a rat model of epileptogenesis : structural connectomics and fixel-based analysis

Emma ChristiaenMarie-Gabrielle GoossensBenedicte DescampsJean DelbekeWytse WadmanKristl VonckPaul BoonRobrecht RaedtChristian Vanhove

A1 Journal Article in BRAIN CONNECTIVITY

2021

Chemogenetic neuromodulation in a rat model of epilepsy

Marie-Gabrielle GoossensPaul BoonRobrecht RaedtChristian Vanhove

Level of hM4D(Gi) DREADD expression determines inhibitory and neurotoxic effects in the hippocampus

Marie-Gabrielle GoossensLars Emil LarsenMarijke VergaelenWytse WadmanChris Van den HauteWayra BrackxSilke ProesmansJana DesloovereEmma ChristiaenErine Craey et al.

A1 Journal Article in ENEURO

Long‐term chemogenetic suppression of seizures in a multifocal rat model of temporal lobe epilepsy

Marie-Gabrielle GoossensPaul BoonWytse WadmanChris Van den HauteVeerle BaekelandtAlain VerstraeteKristl VonckLars Emil LarsenMathieu SprengersEvelien Carrette et al.

A1 Journal Article in EPILEPSIA

2020

Dynamic functional connectivity and graph theory metrics in a rat model of temporal lobe epilepsy

Emma ChristiaenMarie-Gabrielle GoossensBenedicte DescampsRobrecht RaedtChristian Vanhove

Dynamic functional connectivity and graph theory metrics in a rat model of temporal lobe epilepsy reveal a preference for brain states with a lower functional connectivity, segregation and integration

Emma ChristiaenMarie-Gabrielle GoossensBenedicte DescampsLars Emil LarsenPaul BoonRobrecht RaedtChristian Vanhove

A1 Journal Article in NEUROBIOLOGY OF DISEASE

Dynamic functional connectivity and graph theory metrics in a rat model of temporal lobe epilepsy reveal a preference for brain states with a lower functional connectivity, segregation and integration

Emma ChristiaenMarie-Gabrielle GoossensBenedicte DescampsRobrecht RaedtChristian Vanhove

Dynamic functional connectivity in a rat model of temporal lobe epilepsy reveals a preference for brain states with a lower functional connectivity

Emma ChristiaenMarie-Gabrielle GoossensBenedicte DescampsRobrecht RaedtChristian Vanhove

Long-term effect of chemogenetic suppression of excitatory hippocampal neurons on spontaneous seizures in a rat model for temporal lobe epilepsy

Marie-Gabrielle GoossensKristl VonckChris Van den HauteV. BaekelandtWytse WadmanChristian VanhovePaul BoonRobrecht Raedt

The effect of chemogenetic hippocampal suppression on evoked potentials and seizures in a multifocal rat model for temporal lobe epilepsy

Marie-Gabrielle GoossensKristl VonckChris Van den HauteVeerle BaekelandtWytse WadmanChristian VanhovePaul BoonRobrecht Raedt

2019

Alterations in the functional brain network in a rat model of epileptogenesis : a longitudinal resting state fMRI study

Emma ChristiaenMarie-Gabrielle GoossensRobrecht RaedtBenedicte DescampsLars Emil LarsenErine CraeyEvelien CarretteKristl VonckPaul BoonChristian Vanhove

A1 Journal Article in NEUROIMAGE

Chemogenetic suppression of excitatory hippocampal neurons in non-epileptic and epileptic rats

Marie-Gabrielle GoossensEmma ChristiaenPaul BoonKristl VonckChris Van Den HauteVeerle BaekelandtWytse WadmanChristian VanhoveRobrecht Raedt

Chemogenetic suppression of spontaneous seizures in a rat model for temporal lobe epilepsy

Marie-Gabrielle GoossensEmma ChristiaenPaul BoonKristl VonckEvelien CarretteJana DesloovereChris Van Den HauteVeerle BaekelandtWytse WadmanChristian Vanhove et al.

Chemogenetic suppression of spontaneous seizures in a rat model for temporal lobe epilepsy

Marie-Gabrielle GoossensEmma ChristiaenPaul BoonKristl VonckEvelien CarretteJana DesloovereChris Van Den HauteVeerle BaekelandtWytse WadmanChristian Vanhove et al.

Chemogenetic suppression of spontaneous seizures in a rat model for temporal lobe epilepsy

Marie-Gabrielle GoossensEmma ChristiaenPaul BoonKristl VonckEvelien CarretteJana DesloovereChris Van Den HauteVeerle BaekelandtWytse WadmanChristian Vanhove et al.

Chemogenetic therapy strongly suppresses hippocampal excitability and spontaneous seizures in a rat model for temporal lobe epilepsy

Marie-Gabrielle GoossensPaul BoonEmma ChristiaenKristl VonckEvelien CarretteJana DesloovereChris Van den HauteVeerle BaekelandtWytse WadmanChristian Vanhove et al.

Effect of chemogenetic modulation of hippocampal neurons on depression and spatial memory impairment in a rat model for temporal lobe epilepsy

Erine CraeyMarie-Gabrielle GoossensJana DesloovereCaroline MerckxChris Van Den HauteVeerle BaekelandtDimitri De BundelIlse SmoldersKristl VonckPaul Boon et al.

Effect of chemogenetic modulation of hippocampal neurons on depression and spatial memory impairment in a rat model for temporal lobe epilepsy

Erine CraeyMarie-Gabrielle GoossensJana DesloovereCaroline MerckxChris Van Den HauteVeerle BaekelandtDimitri De BundelIlse SmoldersKristl VonckPaul Boon et al.

Long-term chemogenetic suppression of spontaneous seizures in a mouse model for temporal lobe epilepsy.

Jana DeslooverePaul BoonLars Emil LarsenCaroline MerckxMarie-Gabrielle GoossensC Van den HauteV BaekelandtD De BundelEvelien CarretteJean Delbeke et al.

A1 Journal Article in EPILEPSIA

Use of a light-activated chloride channel for the modulation of hippocampal evoked potentials

Anirudh AcharyaMarie-Gabrielle GoossensWouter Van LysebettensLatoya StevensCharlotte GermonpréWytse WadmanV. BaekelandtC. Van den HautePaul BoonAlfred Meurs et al.

2018

Chemogenetic silencing of excitatory hippocampal neurons prevents spontaneous seizures in a mouse model for temporal lobe epilepsy

Jana DesloovereMarie-Gabrielle GoossensChris Van den HauteVeerle BaeckelandtJean DelbekeEvelien CarretteKristl VonckAlfred MeursWytse WadmanPaul Boon et al.

Chemogenetic silencing of excitatory hippocampal neurons prevents spontaneous seizures in a mouse model for temporal lobe epilepsy

Jana DesloovereMarie-Gabrielle GoossensChris Van den HauteVeerle BaeckelandtJean DelbekeEvelien CarretteKristl VonckAlfred MeursWytse WadmanPaul Boon et al.

Chemogenetic silencing of excitatory hippocampal neurons prevents spontaneous seizures in a mouse model for temporal lobe epilepsy

Jana DesloovereMarie-Gabrielle GoossensChris Van den HauteVeerle BaekelandtJean DelbekeEvelien CarretteKristl VonckAlfred MeursWytse WadmanPaul Boon et al.

Chemogenetic silencing of excitatory hippocampal neurons prevents spontaneous seizures in a mouse model for temporal lobe epilepsy

Jana DesloovereMarie-Gabrielle GoossensChris Van den HauteVeerle BaeckelandtJean DelbekeEvelien CarretteKristl VonckAlfred MeursWytse WadmanPaul Boon et al.

Chemogenetic silencing of excitatory hippocampal neurons prevents spontaneous seizures in a mouse model for temporal lobe epilepsy

Jana DesloovereMarie-Gabrielle GoossensChris Van den HauteVeerle BaeckelandtJean DelbekeEvelien CarretteKristl VonckAlfred MeursWytse WadmanPaul Boon et al.

Functional connectivity changes during epileptogenesis : a longitudinal resting-state fMRI study

Emma ChristiaenMarie-Gabrielle GoossensBenedicte DescampsPaul BoonRobrecht RaedtChristian Vanhove

Functional connectivity changes during epileptogenesis : a longitudinal resting-state functional MRI study

Emma ChristiaenMarie-Gabrielle GoossensBenedicte DescampsPaul BoonRobrecht RaedtChristian Vanhove

Functional connectivity changes during epileptogenesis : a longitudinal resting-state functional MRI study

Emma ChristiaenMarie-Gabrielle GoossensBenedicte DescampsPaul BoonRobrecht RaedtChristian Vanhove

Functional connectivity changes during epileptogenesis : a longitudinal rs-fMRI study

Emma ChristiaenMarie-Gabrielle GoossensBenedicte DescampsPaul BoonRobrecht RaedtChristian Vanhove

Functional connectivity changes during epileptogenesis : a longitudinal rs-fMRI study

Emma ChristiaenMarie-Gabrielle GoossensBenedicte DescampsPaul BoonRobrecht RaedtChristian Vanhove

The effect of chemogenetic inhibition of excitatory neurons on hippocampal excitability and seizure frequency in a rat model

Marie-Gabrielle GoossensJana DesloovereEmma ChristiaenWouter Van LysebettensErine CraeyAnirudh AcharyaPaul BoonKristl VonckChris Van Den HauteVeerle Baekelandt et al.

The effect of chemogenetic inhibition of excitatory neurons on hippocampal excitability and seizure frequency in a rat model

Marie-Gabrielle GoossensJana DesloovereEmma ChristiaenWouter Van LysebettensErine CraeyAnirudh AcharyaPaul BoonKristl VonckChris Van Den HauteVeerle Baekelandt et al.

The effect of chemogenetic inhibition of excitatory neurons on hippocampal excitability and seizure frequency in a rat model

Marie-Gabrielle GoossensJana DesloovereEmma ChristiaenWouter Van LysebettensErine CraeyAnirudh AcharyaPaul BoonKristl VonckChris Van Den HauteVeerle Baekelandt et al.

2017

Changes in functional brain networks during epileptogenesis in a rodent model of temporal lobe epilepsy

Emma ChristiaenMarie-Gabrielle GoossensBenedicte DescampsPaul BoonRobrecht RaedtChristian Vanhove

Changes in functional brain networks during epileptogenesis in a rodent model of temporal lobe epilepsy

Emma ChristiaenMarie-Gabrielle GoossensBenedicte DescampsPaul BoonRobrecht RaedtChristian Vanhove

Functional connectivity changes during epileptogenesis: a longitudinal rs-fMRI study

Emma ChristiaenMarie-Gabrielle GoossensBenedicte DescampsPaul BoonRobrecht RaedtChristian Vanhove