Research Explorer

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Researcher

Margarita Craen

Publications & Research Data

Awards & Distinctions

68 Results

2025

Effects of puberty suppression on bone, body composition, handgrip strength and glucolipid profile in early-pubertal transgender adolescents

Silvia CianciaVanessa DuboisMargarita CraenDaniel KlinkCharlotte VerrokenDirk VanderschuerenMartine Cools

A1 Journal Article in INTERNATIONAL JOURNAL OF TRANSGENDER HEALTH

2023

Early puberty suppression and gender-affirming hormones do not alter final height in transgender adolescents

Silvia CianciaDaniel KlinkMargarita CraenMartine Cools

A1 Journal Article in EUROPEAN JOURNAL OF ENDOCRINOLOGY

2022

Effects of long-term puberty suppression and gender-affirming hormones on body composition and metabolic profile in a preclinical mouse model and a cohort of transboys

Vanessa DuboisSilvia CianciaFrank ClaessensMargarita CraenSara El KharrazNari KimDaniel KlinkVera SommersDirk VanderschuerenMartine Cools

Long-term GnRHa use and bone health in transgender adolescents : can a mouse model inform clinical practice?

Silvia CianciaVanessa DuboisFrank ClaessensMargarita CraenStefanie DomsSara El KharrazNari KimDaniel KlinkDirk VanderschuerenMartine Cools

2020

Disproportion and dysmorphism in an adult Belgian population with Turner syndrome : risk factors for chronic diseases?

An-Sofie Van de KelftCharlotte LievensKatya De GrooteLAURENT DEMULIERJulie De BackerGuy T'SjoenMargarita CraenBert CallewaertJean De Schepper

A1 Journal Article in ACTA CLINICA BELGICA

2018

Growth, sexual and bone development in a boy with bilateral anorchia under testosterone treatment guided by the development of his monozygotic twin

SARA VANDEWALLEEva Van CaenegemMargarita CraenYouri TaesJean KaufmanGuy T'Sjoen

A1 Journal Article in JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM

Poor growth response during the first year of growth hormone treatment in short prepubertal children with growth hormone deficiency and born small for gestational age: a comparison of different criteria

Saartje StraetemansMuriel ThomasMargarita CraenRaoul RoomanJean De Schepper

A2 Journal Article in INTERNATIONAL JOURNAL OF PEDIATRIC ENDOCRINOLOGY

Proandrogenic and antiandrogenic progestins in transgender youth : differential effects on body composition and bone metabolism

Lloyd TackMargarita CraenBruno LapauwStefan GoemaereKaatje ToyeJean KaufmanSARA VANDEWALLEGuy T'SjoenHans-Georg ZmierczakMartine Cools

A1 Journal Article in JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

2017

Consecutive cyproterone acetate and estradiol treatment in late-pubertal transgender female adolescents

Lloyd TackRobin HeyseMargarita CraenKarlien DhondtHEIDI VANDEN BOSSCHEJolien LaridaenMartine Cools

A1 Journal Article in JOURNAL OF SEXUAL MEDICINE

Developing and evaluating rare disease educational materials co-created by expert clinicians and patients : the paradigm of congenital hypogonadotropic hypogonadism

Corin BadiuMarco BonomiIvan BorshchevskyMartine CoolsMargarita CraenCristina GhervanMichael HauschildEli HershkovitzErik HrabovszkyAnders Juul et al.

A1 Journal Article in ORPHANET JOURNAL OF RARE DISEASES

2016

Body disproportions and dysmorphisms in a Belgian population of adult women with Turner Syndrome : potential risk factors for chronic diseases?

Charlotte LievensAn-Sofie Van de KelftLaurent DemulierJulie De BackerBert CallewaertMargarita CraenGuy T'SjoenKatya De GrooteJean De Schepper

Cognitive, emotional,and psychosocial functioning of girls treated with pharmacological puberty blockage for idiopathic central precocious puberty

Slawomir WojniuszNina CallensStefan SütterlinStein AnderssonJean De SchepperInge GiesJesse VanbesienKathleen De WaeleSara Van AkenMargarita Craen et al.

A1 Journal Article in FRONTIERS IN PSYCHOLOGY

Consecutive lynestrenol and cross-sex hormone treatment in biological female adolescents with gender dysphoria : a retrospective analysis

Lloyd TackMargarita CraenKarlien DhondtHEIDI VANDEN BOSSCHEJolien LaridaenMartine Cools

A1 Journal Article in BIOLOGY OF SEX DIFFERENCES

Delayed adrenarche may be an additional feature of immunoglobulin super family member 1 deficiency syndrome

Severine Van HulleMargarita CraenBert CallewaertSjoerd JoustraWilma OostdijkMonique LosekootJan Maarten WitMarc Olivier TurgeonDaniel J BernardJean De Schepper

A1 Journal Article in JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY

2015

Evaluation of the hypothalamic-pituitary-adrenal axis and its relationship with central respiratory dysfunction in children with Prader-Willi syndrome

Veronique BeauloyeKarlien DhondtW BuysseA NyakasaneF ZechJean De SchepperSara Van AkenKATHLEEN DE WAELEMargarita CraenI Gies et al.

A1 Journal Article in ORPHANET JOURNAL OF RARE DISEASES

2013

Cardiovascular pathology in males and females with 45,X/46,XY mosaicism

Katya De GrooteMartine CoolsJean De SchepperMargarita CraenInge FrançoisDaniel DevosKarlien CarbonezBenedicte EyskensDaniël De Wolf

A1 Journal Article in PLOS ONE

Longitudinal linear growth and final height is impaired in childhood acute lymphoblastic leukemia survivors after treatment without cranial irradiation

Els VandecruysCatharina DhoogeMargarita CraenYves BenoitJean De Schepper

A1 Journal Article in JOURNAL OF PEDIATRICS

2010

Improved Molecular Diagnostics of Idiopathic Short Stature and Allied Disorders: Quantitative Polymerase Chain Reaction-Based Copy Number Profiling of SHOX and Pseudoautosomal Region 1

B D'haeneJan HellemansMargarita CraenJean De SchepperK DevriendtJP FrynsK KeymolenEveline DebalsA de KleinEM de Jong et al.

A1 Journal Article in JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The endocrine treatment of transsexual adolescents

Martine CoolsMargarita CraenGuy T'Sjoen

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

2008

Concerns, expectations and perception regarding stature, physical appearance and psychosocial functioning before and during high-dose growth hormone treatment of short pre-pubertal children born small for gestational age

K. LagrouC. FroidecoeurM. ThomasG. MassaD. BeckersMargarita CraenC. de BeaufortR. RoomanI. FrancoisC. Heinrichs et al.

A1 Journal Article in HORMONE RESEARCH

Molecular Characterization of Iodotyrosine Dehalogenase Deficiency in Patients with Hypothyroidism

Gijs AfinkWillem KulikHenk OvermarsJanine de RandamieTruus VeenboerArno van CruchtenMargarita CraenCarrie Ris-Stalpers

A1 Journal Article in JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

2007

Effect of 2 years of high-dose growth hormone therapy on cognitive and psychosocial development in short children born small for gestational age

K. LagrouJ. VanderfaeillieC. FroidecocurM. ThomasG. MassaS. TenoutasseMargarita CraenM. C. LebrethonD. BeckersI. Francois et al.

A1 Journal Article in EUROPEAN JOURNAL OF ENDOCRINOLOGY

Lack of evidence of hypervolemia in children with insulin-dependent diabetes mellitus

Ann RaesSara Van AkenMargarita CraenRaymond AMG DonckerwolckeJohan Vande Walle

A1 Journal Article in PEDIATRIC NEPHROLOGY

Renal functional changes in relation to hemodynamic parameters during exercise test in normoalbuminuric insulin dependent children

Ann RaesDirk MatthysRaymond AMG DonckerwolckeMargarita CraenSara Van AkenJohan Vande Walle

A1 Journal Article in ACTA PAEDIATRICA

Renal hemodynamic changes and renal functional reserve in children with type 1 diabetes mellitus

Ann RaesRaymond AMG DonckerwolckeMargarita CraenJohan Vande Walle

Renal hemodynamic changes and renal functional reserve in children with type I diabetes mellitus

Ann RaesRaymond AMG DonckerwolckeMargarita CraenMaraina Che HusseinJohan Vande Walle

A1 Journal Article in PEDIATRIC NEPHROLOGY

2006

A reference frame for blood volume in children and adolescents

Ann RaesSara VAN AKENMargarita CraenRaymond AMG DonckerwolckeJohan Vande Walle

A2 Journal Article in BMC PEDIATRICS

a REFERENCE FRAME FOR BLOODVOLUME IN CHILDREN AND ADOLESCENTS

Ann RaesS VAN AKENMargarita CraenRaymond AMG DonckerwolckeJohan Vande Walle

A2 Journal Article in BMC pediatrics

Implicaties van maternale schildklierziekte voor de foetus en neonaat

Koenraad SmetsMargarita Craen

A2 Journal Article in PATIENT CARE (BELGIE NEDERLANDSE ED.)

2005

Transplacental passage of a nonionic contrast agent

Piet VanhaesebrouckAlain VerstraeteClaudine De PraeterKoenraad SmetsAleksandra ZecicMargarita Craen

A1 Journal Article in EUROPEAN JOURNAL OF PEDIATRICS

2003

Estradiol levels in girls with Turner's syndrome compared to normal prepubertal girls as determined by an ultrasensitive assay

CA WILSONC HEINRICHSKA LARMOREMargarita CraenJ BROWN-DAWSONS SHAYWITZJ ROSSKO KLEIN

A1 Journal Article in JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM

Growth hormone (GH) secretion in patients with childhood-onset GH deficiency: Retesting after one year of therapy and at final height

M THOMASG MASSAM MAESD BECKERSMargarita CraenI FRANCOISC HEINRICHSJP BOURGUIGNON

A1 Journal Article in HORMONE RESEARCH

Late or delayed induced or spontaneous puberty in girls with Turner syndrome treated with growth hormone does not affect final height

G MASSAC HEINRICHSS VERLINDEM THOMASJP BOURGUIGNONMargarita CraenI FRANCOISM DU CAJUM MAESJ DE SCHEPPER

A1 Journal Article in JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM

2001

Final height in children with idiopathic growth hormone deficiency treated with recombinant human growth hormone: The Belgian experience.

M THOMASG MASSAJP BOURGUIGNONMargarita CraenJ DE SCHEPPERF DE ZEGHERL DOOMSM DU CAJUI FRANCOISC HEINRICHS et al.

A1 Journal Article in HORMONE RESEARCH

Sexual precocity after immigration from developing countries to Belgium: evidence of previous exposure to organochlorine pesticides.

M KRSTEVSKA-KONSTANTINOVAC CHARLIERMargarita CraenM DU CAJUC HEINRICHSC DE BEAUFORTG PLOMTEUXJP BOURGUIGNON

A1 Journal Article in HUMAN REPRODUCTION

Sexual precocity after immigration from developing countries to Belgium: evidence of previous exposure to organochlorine pesticides.

M KRSTEVSKA-KONSTANTINOVAC CHARLIERMargarita CraenM DU CAJUC HEINRICHSC DE BEAUFORTG PLOMTEUXJP BOURGUIGNON

A1 Journal Article in APMIS

2000

Clinical and radiographic features of a family with hypochondroplasia owing to a novel Asn540Ser mutation in the fibroblast growth factor receptor 3 gene

Geert MortierLieve NuytinckMargarita CraenJean-Pierre RenardJuliaan LeroyAnne De Paepe

A1 Journal Article in JOURNAL OF MEDICAL GENETICS

1999

Early, discontinuous, high dose growth hormone treatment to normalize height and weight of short children born small for gestational age: Results over 6 years.

F DE ZEGHERMVL DU CAJUC HEINRICHSM MAESJozef De SchepperMargarita CraenK VANWESERP MALVAUXRG ROSENFELD

A1 Journal Article in JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM

Final height in 66 Turner girls treated with GH: Independency of age at onset and dosage of ethinylestradiol therapy.

C HEINRICHSJ DE SCHEPPERF VERLINDENM THOMASG MASSAMargarita CraenP MALVAUXI FRANCOIS

A2 Journal Article in HORMONE RESEARCH

Hypochondroplasie: diagnose en behandeling

Geert MortierMargarita Craen

A2 Journal Article in TIJDSCHRIFT VAN DE BELGISCHE KINDERARTS = JOURNAL DU PEDIATRE BELGE

Le traitement par hormone de croissance dans le syndrome de Turner: l'expérience du B. S. G. P. E.

C HEINRICHSJ DE SCHEPPERG MASSAM THOMASF VERLINDENMargarita CraenP MALVAUXI FRANCOIS

A2 Journal Article in Journal du Pédiatre Belge

Que nous apprend l'évaluation psychologique des enfants et adolescents de petite taille traités par hormone de croissance ?

K LAGROUD XROUET-HEINRICHSMargarita CraenJP CHANOINEJ DE SCHEPPERF DE ZEGHERER DOOMS L

A2 Journal Article in Journal du Pédiatre Belge

Renal hypertrophy is reversible with longterm lisinopril therapy in children with type I diabetes mellitus

Sara Van AkenANN RAESJ VANDE WALLEDirk MatthysMargarita Craen

1998

Age-related perception of stature, acceptance of therapy, and psychosocial functioning in human growth hormone-treated girls with Turner's syndrome.

K LAGROUD XHROUET-HEINRICHSC HEINRICHSMargarita CraenJP CHANOINEP MALVAUXJP BOURGUIGNON

A1 Journal Article in JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM

Hypercalciurie chez des patients diabétiques type I

Sara Van AkenAnn RaesMargarita CraenJohan Vande Walle

1997

Characterisation of two different nonsense mutations, C6792A and C6792G, causing skipping of exon 37 in the NF1 gene.

Ludwine MessiaenT CALLENSA DEPAEPEMargarita CraenGeert Mortier

A1 Journal Article in HUMAN GENETICS

Growth hormone therapy in pre-pubertal children with Noonan syndrome: first year growth response and comparison with Turner syndrome.

J DESCHEPPERBJ OTTENI FRANCOISJP BOURGUIGNONMargarita CraenI VANDERBURGTGG MASSA

A1 Journal Article in ACTA PAEDIATRICA

Longitudinal study of behavioral and affective patterns in girls with central precocious puberty during long-acting triptorelin therapy.

D XHROUET-HEINRICHSK LAGROUC HEINRICHSMargarita CraenL DOOMSP MALVAUXF KANENJP BOURGUIGNON

A1 Journal Article in ACTA PAEDIATRICA

1996

Abnormal circulating pancreatic enzyme activities in more than twenty-five percent of recent-onset insulin-dependent diabetic patients: Association of hyperlipasemia with high-titer islet cell antibodies.

C SEMAKULACL VANDEWALLECFH VANSCHRAVENDIJKJC SODOYEZFC SCHUITA FORIERSA FALORNIMargarita CraenDG PIPELEERSFK GORUS et al.

A1 Journal Article in PANCREAS

High-dose growth hormone treatment of short children born small for gestational age.

F DEZEGHERM MAESSE GARGOSKYC HEINRICHSMVL DUCAJUG THIRYJ DESCHEPPERMargarita CraenL BREYSEMA LOFSTROM et al.

A1 Journal Article in JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM

Reduced decrease of peripheral vascular resistance during exercise in young type I diabetic patients

Dirk MatthysMargarita CraenDaniël De WolfJ VANDEWALLEHenri Verhaaren

A1 Journal Article in DIABETES CARE

Turner-syndroom: multidisciplinaire aanpak

Margarita Craen

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

1995

GROWTH-HORMONE DEFICIENCY AND PREMATURE THELARCHE IN A FEMALE INFANT WITH KABUKI MAKEUP SYNDROME.

K DEVRIENDTL LEMLIMargarita CraenF DEZEGHER

A1 Journal Article in HORMONE RESEARCH

1994

Direct transmission of a tandem duplication in the short arm of chromosome-8.

Catharina DhoogeNadine Van RoyMargarita CraenFranki Speleman

A1 Journal Article in CLINICAL GENETICS

HIGH-DOSE GROWTH-HORMONE THERAPY FOR SHORT CHILDREN BORN SMALL-FOR-GESTATIONAL-AGE.

F DEZEGHERM MAESC HEINRICHSG THIRYMVL DUCAJUJ DESCHEPPERMargarita CraenJP CHANOINEL DOOMSP MALVAUX

A1 Journal Article in ACTA PAEDIATRICA

Variations in pituitary-gonadal suppression during intranasal buserelin and intramuscular depot-triptorelin therapy for central precocious puberty

C HeinrichsMargarita CraenM Vanderschueren-LodeweyckxP MalvauxL FaweJP Bourguignon

A1 Journal Article in ACTA PAEDIATRICA

1993

Effects of human growth hormone therapy on melanocytic naevi

JP BourguignonG PierardC ErnouldC HeinrichsMargarita CraenP RochiccioliJ ArreseC Franchimont

A1 Journal Article in LANCET

Gender difference in aerobic capacity in adolescents after cure from malignant disease in childhood.

Dirk MatthysHenri VerhaarenYves BenoitGenevieve LaureysA DENAEYERMargarita Craen

A1 Journal Article in ACTA PAEDIATRICA

Growth promoting effect of Growth-Hormone and low dose Ethinylestradiol in girls with Turner syndrome: final weight results

G MASSAM MAESP MALVAUXMargarita CraenC ERNOULDM HEINRICHSC VANDEWEGHE

INFLUENCE OF SPONTANEOUS OR INDUCED PUBERTY ON THE GROWTH-PROMOTING EFFECT OF TREATMENT WITH GROWTH-HORMONE IN GIRLS WITH TURNERS SYNDROME.

G MASSAM MAESC HEINRICHSMark VandewegheMargarita CraenM VANDERSCHUEREN-LODEWEYCKX

A1 Journal Article in CLINICAL ENDOCRINOLOGY

On the variability of the Brachmann-De Lange Syndrome in seven patients.

Juliaan LeroyJ PERSIJNV VANDEWEGHER VANHECKEAnn OostraS DEBIEMargarita Craen

A1 Journal Article in AMERICAN JOURNAL OF MEDICAL GENETICS

Verlies aan funktionele renale reservecapaciteit bij de kinderen met diabetes mellitus type I

Ann RaesJohan Vande WalleMargarita Craen

1992

Acute suppurative thyroiditis complicating second allogeneic transplant for juvenile CMML

M PoelmanYves BenoitGenevieve LaureysMargarita CraenJuliaan Leroy

A1 Journal Article in BONE MARROW TRANSPLANTATION

1991

GROWTH-HORMONE (GH) TREATMENT IN SHORT NORMAL-CHILDREN - ABSENCE OF INFLUENCE OF TIME OF INJECTION AND RESISTANCE TO GH AUTOFEEDBACK.

JP CHANOINEM VANDERSCHUEREN-LODEWEYCKXM MAESG THIRY-COUNSONMargarita CraenG VANVLIET

A1 Journal Article in JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM

1990

Identification and characterization of normal length nonfluorescent Y chromosomes: cytogenetic analysis, Southern hybridization and non-isotopic in situ hybridization

Franki SpelemanBart Van der AuweraKathelijne MangelschotsMiet VercruyssenTon RaapJoop WiegantMargarita CraenJuliaan Leroy

A1 Journal Article in HUMAN GENETICS

1989

De novo terminal deletion 7P22.1-pter in a child without craniosynostosis

Franki SpelemanMargarita CraenJuliaan Leroy

A1 Journal Article in JOURNAL OF MEDICAL GENETICS

1988

Factors contributing to the impairment of growth in children with acute lymphoblastic leukemia

KA LoggheJP BourguignonMargarita CraenYves Benoit

A1 Journal Article in HORMONE RESEARCH

Congenital bowing of long bones: a retrospective feature in a dominant syndromal type of shorte stature. Chapter 23 in 'Dysmorphology and Genetics of Cardiovascular Disorders', Bartsocas CS, Beighton P, Eds., HTA Medical Publications, Athens, 1994, pp. 158-165.

JG LEROYGR MORTIERAnn OostraL NUYTINCKAnne De PaepeMargarita CraenJ VAN DER EYKEN