Research Explorer

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Researcher

Marc Bracke

Awards & Distinctions

383 Results

2019

Selective pharmacological inhibitors of HDAC6 reveal biochemical activity but functional tolerance in cancer models

Yves DepetterSilke GeursRob De VreeseSophie GoethalsElien VandoornAlien LaevensJonas SteenbruggeEvelyne MeyerPascal de TullioMarc Bracke et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

2018

Glucocorticoids indirectly decrease colon cancer cell proliferation and invasion via effects on cancer-associated fibroblasts

Zuzanna DrebertElly De VlieghereJolien BridelanceOlivier De WeverKarolien De BosscherMarc BrackeIlse Beck

A1 Journal Article in EXPERIMENTAL CELL RESEARCH

Heterocellular 3D scaffolds as biomimetic to recapitulate the tumor microenvironment of peritoneal metastases in vitro and in vivo

Emiel De JaeghereElly De VlieghereJasper Van HoorickSandra Van VlierbergheGlenn WagemansLeen PietersElodie MelsensMarleen PraetJo Van DorpeMatthieu Boone et al.

A1 Journal Article in BIOMATERIALS

Nieuwe inzichten betreffende metastasen

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Radiotherapy-activated cancer-associated fibroblasts promote tumor progression through paracrine IGF1R activation

Joke TommeleinElly De VlieghereLaurine VersetElodie MelsensJustine LeendersBenedicte DescampsAnnelies DebucquoyChristian VanhovePatrick PauwelsChristian P Gespach et al.

A1 Journal Article in CANCER RESEARCH

Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research

Edward GeeurickxElisa HeyrmanJan Van DeunLien LippensJoeri TulkensBert DhondtGlenn VergauwenKris GevaertFrancis ImpensIlkka Miinalainen et al.

2017

A JAK3/STAT3 passenger activation in a lapatinib-acquired resistance model of HER2-amplified breast cancer

Mieke Van BockstalNadine Van RoyGlenn VergauwenKathleen LambeinVeronique CocquytLouis LibbrechtHannelore DenysMarc BrackeOlivier De Wever

ADAM-17/FHL2 colocalisation suggests interaction and role of these proteins in colorectal cancer

Laurine VersetJoke TommeleinChristine DecaesteckerElly De VlieghereMarc BrackeIsabelle SalmonOlivier De WeverPieter Demetter

A1 Journal Article in TUMOR BIOLOGY

Colon cancer-derived myofibroblasts increase endothelial cell migration by glucocorticoid-sensitive secretion of a pro-migratory factor

Zuzanna DrebertMark MacAskillDahlia Doughty-ShentonKarolien De BosscherMarc BrackePatrick WF HadokeIlse Beck

A1 Journal Article in VASCULAR PHARMACOLOGY

Development of novel blebbistatin derivatives in the quest for improved non-muscle myosin II inhibitors

Sigrid VerhasseltChristian StevensBart RomanMarc Bracke

Discovery of (S)-3′-hydroxyblebbistatin and (S)-3′-aminoblebbistatin : polar myosin II inhibitors with superior research tool properties

Sigrid VerhasseltBart RomanOlivier De WeverKristof Van HeckeRik Van DeunMarc BrackeChristian Stevens

A1 Journal Article in ORGANIC & BIOMOLECULAR CHEMISTRY

Glucocorticoid receptor modulation of the colon cancer microenvironment

Zuzanna DrebertMarc BrackeIlse BeckKarolien De Bosscher

Improved synthesis and comparative analysis of the tool properties of new and existing D-ring modified (S)-blebbistatin analogs

Sigrid VerhasseltBart RomanMarc BrackeChristian Stevens

A1 Journal Article in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Insights into the myosin II inhibitory potency of A-ring-modified (S)-blebbistatin analogs

Sigrid VerhasseltChristian StevensTom Van den broeckeMarc BrackeBart Roman

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Secretome analysis of breast cancer-associated adipose tissue to identify paracrine regulators of breast cancer growth

Lore LapeireAn HendrixEvelyne LecoutereMieke Van BockstalJo VandesompeleDawn MaynardGeert BraemsRudy Van den BroeckeCathérine MüllerMarc Bracke et al.

A1 Journal Article in ONCOTARGET

Stromal reaction and paracrine consequences of radiotherapy in colorectal cancer

Joke TommeleinOlivier De WeverMarc Bracke

When neighbors talk : colon cancer cell invasion and tumor microenvironment myofibroblasts

Jolien BridelanceZuzanna DrebertOlivier De WeverMarc BrackeIlse Beck

A1 Journal Article in CURRENT DRUG TARGETS

2016

4-Fluoro-3',4',5'-trimethoxychalcone as a new anti-invasive agent : from discovery to initial validation in an in vivo metastasis model

Bart RomanLiselot MusTine De RyckMarc BrackeChristian Stevens

4-Fluoro-3',4',5'-trimethoxychalcone as a new anti-invasive agent: from discovery to initial validation in an in vivo metastasis model

Bart RomanLiselot MusMarc BrackeChristian Stevens

4-Fluoro-3',4',5'-trimethoxychalcone as a new anti-invasive agent: from discovery to initial validation in an in vivo metastasis model

Bart RomanLiselot MusTine De RyckMarc BrackeChristian Stevens

Age and cellular context influence rectal prolapse formation in mice with caecal wall colorectal cancer xenografts

Joke TommeleinFélix GremonprezLaurine VersetElly De VlieghereGlenn WagemansChristian GespachTom BoterbergPieter DemetterWim CeelenMarc Bracke et al.

A1 Journal Article in ONCOTARGET

Discovery and development of new anti-invasive agents, an unmet clinical need

Bart RomanLiselot MusTine De RyckMarc BrackeChristian Stevens

Discovery of anti-invasive tools and leads for the study and treatment of metastatic cancer : two case studies

Bart RomanSigrid VerhasseltMarc BrackeChristian Stevens

Discovery of novel nonmuscle myosin II inhibitors as antimetastatic therapeutics leads and chemical tools

Sigrid VerhasseltMarc BrackeChristian StevensBart Roman

Discovery of novel nonmuscle myosin II inhibitors as chemical tools and antimetastatic therapeutics leads

Sigrid VerhasseltMarc BrackeChristian StevensBart Roman

Dissemination and adhesion of peritoneal cancer cells to the peritoneal wall

Elly De VlieghereMarc BrackeLaurine VersetPieter DemetterOlivier De Wever

Bookchapter in Intraperitoneal cancer therapy : principles and practice

Genipin-crosslinked gelatin microspheres as a strategy to prevent postsurgical peritoneal adhesions : in vitro and in vivo characterization

Kaat De ClercqCharlotte SchelfhoutMarc BrackeOlivier De WeverMieke Van BockstalWim CeelenJean Paul RemonChris Vervaet

A1 Journal Article in BIOMATERIALS

NewTumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells

Elly De VlieghereMarc BrackePieter DemetterWim CeelenChristian VanhoveBruno De GeestOlivier De Wever

Pharmacological evaluation of the anti-invasive agent 4-fluoro-3',4',5'-trimethoxychalcone

Bart RomanLiselot MusTine De RyckMarc BrackeChristian Stevens

Quantitative and functional requirements for bioluminescent cancer models

Lynn FeysBenedicte DescampsChristian VanhoveStefan VermeulenJo VandesompeleKatrien VanderheydenKathy MessensMarc BrackeOlivier De Wever

A1 Journal Article in IN VIVO

Quantitative evaluation of single cell spread on collagen matrices

Elly De VlieghereGlenn WagemansS De BackerZuzanna DrebertJoke TommeleinQuentin RousseauB WeynMarleen Van TroysMarc BrackeOlivier De Wever

A1 Journal Article in EXPERIMENTAL CELL RESEARCH

Radiation-induced collateral damage : impact on metastasis

Lynn FeysOlivier De WeverMarc Bracke

Radiation-induced collateral damage : impact on metastasis

Lynn FeysMarc BrackeOlivier De Wever

Selective glucocorticoid receptor-activating adjuvant therapy in cancer treatments

Nora SundahlDorien ClarisseMarc BrackeFritz OffnerWim Vanden BergheIlse Beck

A2 Journal Article in ONCOSCIENCE

The effects of quorum sensing peptides on colon cancer cells: implications for the role of the gut microbiome

Yorick JanssensEvelien WynendaeleFrederick VerbekeAn HendrixOlivier De WeverMarc BrackeBart De Spiegeleer

2015

4-Fluoro-3',4',5'-trimethoxychalcone as a new anti-invasive agent: from discovery to initial validation in an in vivo metastasis model

Bart RomanTine De RyckAtanos PatronovSvetoslav H SlavovBarbara WA VanhoeckeAlan R KatritzkyMarc BrackeChristian Stevens

A1 Journal Article in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

8-prenylnaringenin and tamoxifen inhibit the shedding of irradiated epithelial cells and increase the latency period of radiation-induced oral mucositis

Tine De RyckAnnouchka Van ImpeBarbara VanhoeckeArne HeyerickLuc VakaetWilfried De NeveDoreen MüllerMargret SchmidtWolfgang DörrMarc Bracke

A1 Journal Article in STRAHLENTHERAPIE UND ONKOLOGIE

Anti-inflammatory and antioxidant properties of Piper species: a perspective from screening to molecular mechanisms

Sarvesh KumarShashwat MalhotraAshok K PrasadErik V Van der EyckenMarc BrackeWilliam G Stetler-StevensonVirinder S ParmarBalaram Ghosh

A1 Journal Article in CURRENT TOPICS IN MEDICINAL CHEMISTRY

Biomimics of the peritoneal tumor-environment

Elly De VlieghereMarc BrackeJean Paul Remon

Cancer-associated fibroblasts as target and tool in cancer therapeutics and diagnostics

Elly De VlieghereLaurine VersetPieter DemetterMarc BrackeOlivier De Wever

A1 Journal Article in VIRCHOWS ARCHIV

Cancer-associated fibroblasts connect metastasis-promoting communication in colorectal cancer

Joke TommeleinLaurine VersetTom BoterbergPieter DemetterMarc BrackeOlivier De Wever

A1 Journal Article in FRONTIERS IN ONCOLOGY

Chick heart invasion assay for testing the invasiveness of cancer cells and the activity of potentially anti-invasive compounds

Marc BrackeBart RomanChristian StevensLiselot MusVirinder ParmarOlivier De WeverMarcus Mareel

A1 Journal Article in JOVE-JOURNAL OF VISUALIZED EXPERIMENTS

Combination of dexamethasone with the selective glucocorticoid receptor modulator, Compound A, does not enhance glucocorticoid responsiveness in lymphoid malignancies

Dorien ClarisseFritz OffnerMarc BrackeKarolien De BosscherIlse Beck

Combined inhibition of rho-associated protein kinase and EGFR suppresses the invasive phenotype in EGFR-dependent lung cancer cells

Ijeoma Adaku UmeloOlivier De WeverPeter KronenbergerAlfiah NoorErik TeugelsGang ChenMarc BrackeJacques De Grève

A1 Journal Article in LUNG CANCER

Combined targeting of EGFR/HER promotes anti-tumor efficacy in subsets of KRAS mutant lung cancer resistant to single EGFR blockade

Ijeoma Adaku UmeloOlivier De WeverPeter KronenbergerJan Van DeunAlfiah NoorKshitiz SinghErik TeugelsGang ChenMarc BrackeJacques De Grève

A1 Journal Article in ONCOTARGET

Communication of quorum sensing peptides with breast cancer cells

Frederick VerbekeEvelien WynendaeleMarianne LauwersAn HendrixChristian BurvenichOlivier De WeverMarc BrackeBart De Spiegeleer

Crosstalk between the microbiome and cancer cells by quorum sensing peptides

Evelien WynendaeleFrederick VerbekeMatthias D'HondtAn HendrixChristophe Van De WieleChristian BurvenichKathelijne PeremansOlivier De WeverMarc BrackeBart De Spiegeleer

A1 Journal Article in PEPTIDES

Data on in vivo selection of SK-OV-3 Luc ovarian cancer cells and intraperitoneal tumor formation with low inoculation numbers

Elly De VlieghereCharlotte CarlierWim CeelenMarc BrackeOlivier De Wever

A2 Journal Article in DATA IN BRIEF

Dynamic shifts in the oral microbiome during radiotherapy

Tine De RyckFréderic DuprezMarc BrackeTom Van de WieleBarbara Vanhoecke

A2 Journal Article in CLINICAL RESEARCH IN INFECTIOUS DISEASES

Effects of irradiation on epithelial wound healing and microbial diversity in an in-vitro oral mucosa model

Tine De RyckTom BoterbergFrederiek-Maarten KerckhofJoachim De SchrijverMarc BrackeTom Van De WieleBarbara Vanhoecke

A2 Journal Article in JOURNAL OF NUCLEAR MEDICINE AND RADIATION THERAPY

Further studies on anti-invasive chemotypes: an excursion from chalcones to curcuminoids

Bart RomanTine De RyckSigrid VerhasseltMarc BrackeChristian Stevens

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Glucocorticoids and the non-steroidal selective glucocorticoid receptor modulator, compound A, differentially affect colon cancer-derived myofibroblasts

Zuzanna DrebertMarc BrackeIlse Beck

A1 Journal Article in JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Impact of neoadjuvant therapy on cancer-associated fibroblasts in rectal cancer

Laurine VersetJoke TommeleinXavier Moles LopezChristine DecaesteckerTom BoterbergElly De VlieghereIsabelle SalmonMarcus MareelMarc BrackeOlivier De Wever et al.

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

Microbial inhibition of oral epithelial wound recovery: potential role for quorum sensing molecules?

Tine De RyckEline VanlanckerCharlotte GrootaertBart RomanLaurens De CoenIsabel VandenbergheChristian StevensMarc BrackeTom Van de WieleBarbara Vanhoecke

A1 Journal Article in AMB EXPRESS

Radiation-induced lung damage promotes breast cancer lung-metastasis through CXCR4 signaling

Lynn FeysBenedicte DescampsChristian VanhoveAnne VralLiv VeldemanStefan VermeulenCarlos De WagterMarc BrackeOlivier De Wever

A1 Journal Article in ONCOTARGET

Radiotherapy-induced oral mucositis : the host-microbe interactions come into play

Tine De RyckMarc BrackeTom Van de WieleBarbara Vanhoecke

Stromal protein expression in breast cancer is differentially regulated by TGF-β1

Mieke Van BockstalKathleen LambeinMireille Van GeleElly De VlieghereRidha LimameGeert BraemsMarc BrackeHannelore DenysLouis LibbrechtOlivier De Wever

Structure-activity relationship studies of 4-methylcoumarin derivatives as anticancer agents

Ramin MiriMaryam NejatiLuciano SasoFatemeh KhakdanBadri ParshadDivya MathurVirinder S ParmarMarc BrackeAshok K PrasadSunil K Sharma et al.

A1 Journal Article in PHARMACEUTICAL BIOLOGY

The competence of 7,8-diacetoxy-4-methylcoumarin and other polyphenolic acetates in mitigating the oxidative stress and their role in angiogenesis

Rini JoshiVishwajeet RohilShvetambri AroraSushma ManralAjit KumarSanjay GoelNivedita PriyaPrabhjoth SinghPrija PonnanSuvro Chatterji et al.

A1 Journal Article in CURRENT TOPICS IN MEDICINAL CHEMISTRY

The quorum sensing peptides PhrG, CSP and EDF promote angiogenesis and invasion of breast cancer cells in vitro

Bart De SpiegeleerFrederick VerbekeMatthias D'HondtAn HendrixChristophe Van De WieleChristian BurvenichKathelijne PeremansOlivier De WeverMarc BrackeEvelien Wynendaele

A1 Journal Article in PLOS ONE

The serum estradiol concentration is the main determinant of the estradiol concentration in normal breast tissue

Herman DepypereSelin BolcaMarc BrackeJoris DelangheFrank ComhairePhillip Blondeel

A1 Journal Article in MATURITAS

Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells

Elly De VlieghereFélix GremonprezLaurine VersetLore MariënChristopher JonesBram De CraeneGeert BerxBenedicte DescampsChristian VanhoveJean Paul Remon et al.

A1 Journal Article in BIOMATERIALS

2014

An immunogen synthesis strategy for the development of specific anti-deoxynivalenol monoclonal antibodies

Melanie SandersYirong GuoAbhishek IyerYara Ruiz GarciaAnastasia GalvitaArne HeyerickDieter DeforceMartijn RisseeuwSerge Van CalenberghMarc Bracke et al.

A1 Journal Article in FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT

Cancer-associated adipose tissue promotes breast cancer progression by paracrine Oncostatin M and JAK3/STAT3 signaling

Lore LapeireAn HendrixKathleen LambeinMieke Van BockstalGeert BraemsRudy Van den BroeckeRidha LimamePieter MestdaghJo VandesompeleChristian Vanhove et al.

Cancer-associated adipose tissue promotes breast cancer progression by paracrine Oncostatin M and Jak/STAT3 signaling

Lore LapeireAn HendrixKathleen LambeinMieke Van BockstalGeert BraemsRudy Van den BroeckeRIDHA LIMAMEPieter MestdaghJo VandesompeleChristian Vanhove et al.

A1 Journal Article in CANCER RESEARCH

Carcinoma-associated fibroblasts provide operational flexibility in metastasis

Olivier De WeverMieke Van BockstalMarcus MareelAn HendrixMarc Bracke

A1 Journal Article in SEMINARS IN CANCER BIOLOGY

Cell aggregation assays

Delphine DebruyneTom BoterbergMarc Bracke

Bookchapter in Metastasis research protocols

Chick heart invasion assay

Marc BrackeVirinder S ParmarAnthony L DePassChristian StevensBarbara VanhoeckeMarcus Mareel

Bookchapter in Metastasis research protocols

Crosstalk between mammalian cells and the microbiome through quorum sensing peptides, influencing cancer metastasis

Evelien WynendaeleFrederick VerbekeMatthias D'HondtAn HendrixChristophe Van De WieleChristian BurvenichKathelijne PeremansOlivier De WeverMarc BrackeBart De Spiegeleer

DFT/B3LYP calculated bond-dissociation enthalpies, radical-scavenging and antioxidant activities of natural-like coumarins

SE AngelovaAK Slavova-KasakovaL SasoSV MalhotraAK PrasadMarc BrackeVS ParmarVD Kancheva

A1 Journal Article in BULGARIAN CHEMICAL COMMUNICATIONS

Development of an oral mucosa model to study host-microbiome interactions during wound healing

Tine De RyckCharlotte GrootaertLaura JaspaertFrederiek-Maarten KerckhofMireille Van GeleJoachim De SchrijverPieter Van den AbbeeleSimon SwiftMarc BrackeTom Van de Wiele et al.

A1 Journal Article in APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Differential regulation of extracellular matrix protein expression in carcinoma-associated fibroblasts by TGF-β1 regulates cancer cell spreading but not adhesion

Mieke Van BockstalKathleen LambeinMireille Van GeleElly De VlieghereRIDHA LIMAMEGeert BraemsRudy Van den BroeckeVeronique CocquytHannelore DenysMarc Bracke et al.

A2 Journal Article in ONCOSCIENCE

Heterologous screening of hybridomas for the development of broad-specific monoclonal antibodies against deoxynivalenol and its analogues

Yirong GuoMelanie SandersAnastasia GalvitaArne HeyerickDieter DeforceMarc BrackeS EreminSarah De Saeger

A1 Journal Article in WORLD MYCOTOXIN JOURNAL

How does the human microbiome affect cancer outcome?

Evelien WynendaeleFrederick VerbekeMatthias D'HondtAn HendrixChristophe Van De WieleChristian BurvenichKathelijne PeremansOlivier De WeverMarc BrackeBart De Spiegeleer

Mesenchymal stem cell secreted platelet derived growth factor exerts a pro-migratory effect on resident Cardiac Atrial appendage Stem Cells

Severina WindmoldersAstrid De BoeckRemco KoninckxAnnick DaniëlsOlivier De WeverMarc BrackeMarc HendrikxKaren HensenJean-Luc Rummens

A1 Journal Article in JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Micro-particle encapsulated carcinoma-associated fibroblast (CAF) deceive and redirect disseminated cancer cells

Elly De VlieghereLaurine VersetChristian VanhoveLore MariënJean Paul RemonPieter DemetterMarc BrackeBruno De GeestOlivier De Wever

Modifications of cell signalling and redox balance by targeting protein acetylation using natural and engineered molecules: implications in cancer therapy

Kavya VenkateswaranAmit VermaAnant N BhattPaban K AgrawalaHanumantharao G RajShashwat MalhotraAshok K PrasadOlivier De WeverMarc BrackeLuciano Saso et al.

A1 Journal Article in CURRENT TOPICS IN MEDICINAL CHEMISTRY

New and selective methods for the detection of phytoestrogens in biological matrices

Ciska WynsDieter DeforceMarc Bracke

On the quest for new anti-invasive agents: from the discovery of 4-fluoro-3',4','5'-trimethoxychalcone to its initial validation in an in vivo metastasis model

Bart RomanTine De RyckSigrid VerhasseltAlan KatritzkyMarc BrackeChristian Stevens

On-chip light sheet illumination enables diagnostic size and concentration measurements of membrane vesicles in biofluids

Hendrik DeschoutKoen RaemdonckStephan StremerschPietro MaoddiGuillaume MernierPhilippe RenaudSebastien JiguetAn HendrixMarc BrackeRudy Van den Broecke et al.

A1 Journal Article in NANOSCALE

Pharmacological levels of withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells

Katarzyna Szarc vel SzicKen Op De BeeckDariusz RatmanAn WoutersIlse BeckKen DeclerckKaren HeyninckErik FransenMarc BrackeKarolien De Bosscher et al.

A1 Journal Article in PLOS ONE

Quorum sensing peptides: missing link between microbiome and health?

Evelien WynendaeleFrederick VerbekeMatthias D'HondtAn HendrixChristophe Van De WieleChristian BurvenichKathelijne PeremansOlivier De WeverMarc BrackeBart De Spiegeleer

Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-κB and AP-1

Karolien De BosscherIlse BeckLien DejagerNadia BougarneAnthoula GaigneauxSebastien ChateauvieuxDariusz RatmanMarc BrackeJan TavernierWim Vanden Berghe et al.

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

Single cell and spheroid collagen type I invasion assay

Olivier De WeverAn HendrixAstrid De BoeckFrank EertmansWendy WestbroekGeert BraemsMarc Bracke

Bookchapter in Metastasis research protocols

Sub-emetic toxicity of Bacillus cereus toxin cereulide on cultured human enterocyte-like Caco-2 cells

Andreja RajkovicCharlotte GrootaertAna ButoracTatiana CucuBruno De MeulenaerJohn Van CampMarc BrackeMieke UyttendaeleVišnja Bačun-DružinaMario Cindrćc

A1 Journal Article in TOXINS

The HMI™ module: a new tool to study the host-microbiota interaction in the human gastrointestinal tract in vitro

Massimo MarzoratiBarbara VanhoeckeTine De RyckMehdi Sadaghian SadabadIris PinheiroSam PossemiersPieter Van den AbbeeleLara DeryckeMarc BrackeJan Pieters et al.

A1 Journal Article in BMC MICROBIOLOGY

The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

Jan Van DeunPieter MestdaghRaija SormunenLotte PyfferoenKarim VermaelenVeronique CocquytJo VandesompeleMarc BrackeOlivier De WeverAn Hendrix

The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

Jan Van DeunPieter MestdaghRaija SormunenVeronique CocquytKarim VermaelenJo VandesompeleMarc BrackeOlivier De WeverAn Hendrix

A2 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

2013

Assessment of the antineoplastic potential of chalcones in animal models

Bart RomanThomas HeugebaertMarc BrackeChristian Stevens

A1 Journal Article in CURRENT MEDICINAL CHEMISTRY

Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling

Astrid De BoeckPatrick PauwelsKaren HensenJean-Luc RummensWendy WestbroekAn HendrixDawn MaynardHannelore DenysKathleen LambeinGeert Braems et al.

A1 Journal Article in GUT

CAF-encapsulated mico-particels capture free cancer cells from the peritoneal fluid

Elly De VlieghereLaurine VersetChristian VanhoveLore MariënJean Paul RemonPieter DemetterMarc BrackeBruno De GeestOlivier De Wever

Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation

Ilse BeckZuzanna DrebertRuben Hoya-AriasAli A BaharMichael DevosDorien ClarisseSofie DesmetNadia BougarneBart RuttensValerie Gossye et al.

A1 Journal Article in PLOS ONE

Design, synthesis and structure-activity relationships of some novel, highly potent anti-invasive (E)- and (Z)-stilbenes

Bart RomanLaurens De CoenSéverine MortierTine De RyckBarbara VanhoeckeAlan R KatritzkyMarc BrackeChristian Stevens

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

Differential secretome analysis of cancer-associated fibroblasts and bone marrow-derived precursors to identify microenvironmental regulators of colon cancer progression

Astrid De BoeckAn HendrixDawn MaynardMieke Van BockstalAnnick DaniëlsPatrick PauwelsChristian GespachMarc BrackeOlivier De Wever

A1 Journal Article in PROTEOMICS

ER stress in diffuse large B cell lymphoma: GRP94 is a possible biomarker in germinal center versus activated B-cell type

Jerina BoelensJean-Philippe JaisBarbara VanhoeckeIlse BeckHeleen Van MelckebekeJan PhilippéMarc BrackeFabrice JardinJosette BrièreKaren Leroy et al.

A1 Journal Article in LEUKEMIA RESEARCH

Epithelial expression of FHL2 is negatively associated with metastasis-free and overall survival in colorectal cancer

L VersetJoke TommeleinX Moles LopezCarolien DecaesteckerMarcus MareelMarc BrackeIlse SalmonOlivier De WeverP Demetter

A1 Journal Article in BRITISH JOURNAL OF CANCER

Frondoside A suppressive effects on lung cancer survival, tumor growth, angiogenesis, invasion, and metastasis

Samir AttoubKholoud ArafatAn GelaudeMahmood Ahmed Al SultanMarc BrackePeter CollinTakashi TakahashiThomas E AdrianOlivier De Wever

A1 Journal Article in PLOS ONE

Protein secretome analysis of evolving and responding tumor ecosystems

Olivier De WeverAstrid De BoeckDawn MaynardMarc BrackeAn Hendrix

A1 Journal Article in CURRENT PROTEOMICS

Rab27B-mediated metabolic reprogramming induces secretome acidification and chemoresistance in breast cancer cells

An HendrixCarla CicconeChristian GespachMarc BrackeOlivier De WeverWendy Westbroek

A2 Journal Article in EXOSOMES AND MICROVESICLES

Radiation-induced myosin IIA expression stimulates collagen type I matrix reorganization

Stéphanie BlockhuysBart Van RompayeRiet De RyckeKathleen LambeinKathleen ClaesMarc BrackeCarlos De WagterOlivier De Wever

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

Targeted liposome-loaded microbubbles for cell-specific ultrasound-triggered drug delivery

Bart GeersOlivier De WeverJo DemeesterMarc BrackeStefaan De SmedtIne Lentacker

A1 Journal Article in SMALL

The in ovo CAM-assay as a xenograft model for sarcoma

Gwen SysLore LapeireNikita StevensHerman FavoreelRamses ForsythMarc BrackeOlivier De Wever

A1 Journal Article in JOVE-JOURNAL OF VISUALIZED EXPERIMENTS

Unraveling the mechanisms behind the enhanced MTT conversion by irradiated breast cancer cells

Stéphanie BlockhuysBarbara VanhoeckeJoél SmetBoel De PaepeRudy Van CosterMarc BrackeCarlos De Wagter

A1 Journal Article in RADIATION RESEARCH

Vacuolar H+ ATPase expression and activity is required for Rab27B dependent invasive growth and metastasis of breast cancer

An HendrixRaija SormunenWendy WestbroekKathleen LambeinHannelore DenysGwen SysGeert BraemsRudy Van den BroeckeVeronique CocquytChristian Gespach et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

2012

(Q)SAR directed design, synthesis and evaluation of anti-invasive chalcones and analogues

Bart RomanMarc BrackeAlan R KatritzkyChristian Stevens

An immobilized antibody targeting N-cadherin facilitates spread of N-cadherin-positive tumour cells

Danielle MaesMarc BrackePiet Ost

A1 Journal Article in ANTICANCER RESEARCH

An immunohistochemical analysis of Rab27B distribution in fetal and adult tissue

An HendrixKathleen LambeinWendy WestbroeckMiguel C SeabraVeronique CocquytPatrick PauwelsMarc BrackeChristian GespachOlivier De Wever

A1 Journal Article in INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Angiopoietin-like protein 4 : health effects, modulating agents and structure-function relationships

Charlotte GrootaertTom Van de WieleWilly VerstraeteMarc BrackeBarbara Vanhoecke

A1 Journal Article in EXPERT REVIEW OF PROTEOMICS

Bone marrow-derived mesenchymal stem cells in colorectal cancer: NRG at the invasion front

Astrid De BoeckMarc BrackeOlivier De Wever

DNA methylation-based biomarkers in serum of patients with breast cancer

Lien Van de VoordeReinhart SpeeckaertDirk Van GestelMarc BrackeWilfried De NeveJoris DelangheMarijn Speeckaert

A1 Journal Article in MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Development of a nanocrystalline Paclitaxel formulation for HIPEC treatment

Lieselotte De SmetPieter ColinWim CeelenMarc BrackeJan Van BocxlaerJean Paul RemonChris Vervaet

A1 Journal Article in PHARMACEUTICAL RESEARCH

Exploration of the SAR of anti-invasive chalcones: synthesis and biological evaluation of conformationally restricted analogues

Bart RomanTine De RyckLaura DierickxBarbara VanhoeckeAlan R KatritzkyMarc BrackeChristian Stevens

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

Exploration of the SAR of anti-invasive chalcones: synthesis and biological evaluation of conformationally restricted analogues

Bart RomanTine De RyckMarc BrackeAlan KatritzkyChristian Stevens

Identification of a GαGβγ, AKT and PKCα signalome associated with invasive growth in two genetic models of human breast cancer cell epithelial-to-mesenchyinal transition

Radia Ouelaa-BenslamaOlivier De WeverAn HendrixMichèle SabbahKathleen LambeinDavid LandGrégoire PrévostMarc BrackeMien-Chie HungAnnette K Larsen et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF ONCOLOGY

Multi-targeting the ERBB receptors may overcome EGFR-T790M-mediated resistance to tyrosine kinase inhibitors

IA UmeloOlivier De WeverE TeugelsG ChenMarc BrackeJ de Greve

N-Cadherin in neuroblastoma disease : expression and clinical significance

Tim LammensKatrien SwertsLara DeryckeANNEMIE DE CRAEMERSara De BrouwerKatleen De PreterNadine Van RoyJo VandesompeleFranki SpelemanJan Philippé et al.

A1 Journal Article in PLOS ONE

Persistent subretinal fluid after surgery for rhegmatogenous retinal detachment: hypothesis and review

Marc VeckeneerLara DeryckeEW LindstedtJ van MeursMaria CornelissenMarc BrackeElisabeth Van Aken

A1 Journal Article in GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Phenolic composition and in vitro bioactivities of 12 morphologically heterogeneous bamboo species

Laura Van HoyweghenDieter DeforceMarc Bracke

Prenylated chalcone xanthohumol associates with histones in breast cancer cells: a novel target identified by a monoclonal antibody

Ciska WynsKatleen Van SteendamBarbara VanhoeckeDieter DeforceMarc BrackeArne Heyerick

A1 Journal Article in MOLECULAR NUTRITION & FOOD RESEARCH

QSAR directed design, synthesis and evaluation of anti-invasive chalcones and analogues

Bart RomanTine De RyckMarc BrackeAlan KatritzkyChristian Stevens

QSAR-directed design, synthesis and evaluation of anti-invasive chalcones and analogues

Bart RomanChristian StevensMarc Bracke

Rab27B, an ex(o)citing driver of breast cancer growth, invasion and metastasis

An HendrixWendy WestbroekMarc BrackeOlivier De Wever

Soy consumption during menopause

Selin BolcaMarc BrackeHerman Depypere

A2 Journal Article in FACTS, VIEWS & VISION IN OBGYN

Tumor grafts derived from sarcoma patients retain tumor morphology, viability, and invasion potential and indicate disease outcomes in the chick chorioallantoic membrane model

Gwen SysMieke Van BockstalRamses ForsythMaurice BalkeBart PoffynDirk UyttendaeleMarc BrackeOlivier De Wever

A1 Journal Article in CANCER LETTERS

2011

Adherence and viability of intestinal bacteria to differentiated Caco-2 cells quantified by flow cytometry

Charlotte GrootaertNico BoonFjoralba ZekaBarbara VanhoeckeMarc BrackeWilly VerstraeteTom Van de Wiele

A1 Journal Article in JOURNAL OF MICROBIOLOGICAL METHODS

Adipose tissue in breast cancer : not an idle bystander but an active participant in breast cancer progression

Lore LapeireAn HendrixKathleen LambeinGeert BraemsP ValetRudy Van den BroeckeMarc BrackeVeronique CocquytHannelore DenysOlivier De Wever

Bacterial modulation of the fasting-induced adipose factor (FIAF): an example of host-microbe crosstalk related to obesity

Charlotte GrootaertTom Van de WieleIlse Van RoosbroeckSam PossemiersAnne-Sophie Vercoutter-EdouartWilly VerstraeteMarc BrackeBarbara Vanhoecke

Bacterial monocultures, propionate, butyrate and H(2)O(2) modulate the expression, secretion and structure of the fasting-induced adipose factor in gut epithelial cell lines

Charlotte GrootaertTom Van de WieleIlse Van RoosbroeckSam PossemiersAnne-Sophie Vercoutter-EdouartWilly VerstraeteMarc BrackeBarbara Vanhoecke

A1 Journal Article in ENVIRONMENTAL MICROBIOLOGY

Bioavailability of hop-derived iso-α-acids and reduced derivatives

Ko CattoorJean Paul RemonKoen BousseryJan Van BocxlaerMarc BrackeDenis De KeukeleireDieter DeforceArne Heyerick

A1 Journal Article in FOOD & FUNCTION

De invloed van fysieke activiteit, BMI en insulinemetabolisme op het risico op borstkanker bij de postmenopauzale vrouw

LIESBETH OTTOYMarc BrackePetra De SutterHerman Depypere

A4 Journal Article in GUNAÏKEIA (NEDERLANDSE EDITIE)

Developmental and cancer research on the mammary gland nowadays: preface

Marc BrackeOlivier De Wever

Editorial material

Diagnostiek en prognose van kanker

Filip LardonTony LahoutteHendrik De RaeveMarc BrackePeter Vandenberghe

Bookchapter in Kanker biomedisch bekeken

EGFR in melanoma : clinical significance and potential therapeutic target

Barbara BooneKoen JacobsLiesbeth FerdinandeJasmien TaildemanJo LambertMarc PeetersMarc BrackePatrick PauwelsLieve Brochez

A1 Journal Article in JOURNAL OF CUTANEOUS PATHOLOGY

Experimental procedures to assay invasion-associated activities of primary cultured fibroblasts

An HendrixKoen JacobsAstrid De BoeckWendy WestbroeckMarc BrackeOlivier De Wever

Bookchapter in Mouse as a model organism : from animal to cells

From the laboratory to the patient and back: an interview with Marc Mareel

A1 Journal Article in INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Het metabolisme van de kankercel en van de patiënt met kanker

Johan SwinnenMarc Bracke

Bookchapter in Kanker biomedisch bekeken

In vitro effects of the intestinal microbiota and their prebiotic modulation on parameters regulating fat metabolism

Charlotte GrootaertWilly VerstraeteMarc Bracke

Inhibition of cell survival, invasion, tumor growth and histone deacetylase activity by the dietary flavonoid luteolin in human epithelioid cancer cells

Samir AttoubAhmed H HassanBarbara VanhoeckeRabah IratniTakashi TakahashiAnne-Marie GabenMarc BrackeSalma AwadAnne JohnHamda Ahmed Kamalboor et al.

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACOLOGY

Invasie en metastasering

Marc BrackeOlivier De WeverLuc Vakaet

Bookchapter in Kanker biomedisch bekeken

Kankerceldood en p53

Bea PauwelsPeter VandenbergheTom Van MaerkenFilip LardonKarin Vanderkerken

Bookchapter in Kanker biomedisch bekeken

Kankerstamcellen

Viggo Van TendelooAstrid De BoeckEls Van Valckenborgh

Bookchapter in Kanker biomedisch bekeken

Microbial reuterin production and its effects on a 3-D model of colonic epithelium

Rosemarie De WeirdtAurélie CrabbéStefan RoosChristophe LacroixWilly VerstraeteBarbara VanhoeckeMarc BrackeCheryl A NickersonTom Van de Wiele

P-cadherin expression reduces melanoma growth, invasion, and responsiveness to growth factors in nude mice

Koen JacobsLynn FeysBarbara VanhoeckeVeerle Van MarckMarc Bracke

A1 Journal Article in EUROPEAN JOURNAL OF CANCER PREVENTION

P-cadherin in adhesion and invasion: opposite roles in colon and bladder carcinoma

Veerle Van MarckChristophe StoveKoen JacobsGert Van den EyndenMarc Bracke

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Priming and potentiation of DNA damage response by fibronectin in human colon cancer cells and tumor-derived myofibroblasts

Olivier De WeverJoëlle Sobczak-ThépotAnne-Sophie Vercoutter-EdouartJean-Claude MichalskiRadia Ouelaa-BenslamaDwayne G StupackMarc BrackeJean YJ Wangchristian GespachShahin Emami

A1 Journal Article in INTERNATIONAL JOURNAL OF ONCOLOGY

Production of monoclonal antibodies against hop-derived (Humulus lupulus L.) prenylflavonoids and the development of immunoassays

Ciska WynsLara DeryckeBram SoenenSelin BolcaDieter DeforceMarc BrackeArne Heyerick

A1 Journal Article in TALANTA

Rab27B, een biomarker voor ER-positieve borsttumoren met slechte prognose?

An HendrixMarc BrackeOlivier De Wever

A2 Journal Article in ONCO (NEDERLANDSE ED.)

Rab27B, een biomarker voor ER-positieve borsttumoren met slechte prognose?

An HendrixMarc BrackeOlivier De Wever

A4 Journal Article in GUNAÏKEIA (NEDERLANDSE EDITIE)

The role of non-muscle myosin IIA in aggregation and invasion of human MCF-7 breast cancer cells

Lara DeryckeChristophe StoveAnne-Sophie Vercoutter-EdouartOlivier De WeverLaurent DolléNathalie ColpaertHerman DepypereJean-Claude MichalskiMarc Bracke

A1 Journal Article in INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

The tumor ecosystem regulates the roads for invasion and metastasis

An HendrixChristian GespachMarc BrackeOlivier De Wever

A1 Journal Article in CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY

2010

An ex(o)citing machinery for invasive tumor growth

An HendrixWendy WestbroekMarc BrackeOlivier De Wever

A1 Journal Article in CANCER RESEARCH

Characterization of the unfolded protein response by pharmacological agents in lymphoid malignancies

Sofie LustFritz OffnerMarc Bracke

Direct Effects of Delta Opioid Receptor Agonists on Invasion-associated Activities of HCT-8/E11 Colon Cancer Cells

Delphine DebruyneA LeroyOlivier De WeverLuc VakaetMarcus MareelMarc Bracke

A1 Journal Article in ANTICANCER RESEARCH

Disposition of hop prenylflavonoids in human breast tissue

Selin BolcaJinghu LiDejan NikolicNathalie RochePhillip BlondeelSam PossemiersDenis De KeukeleireMarc BrackeArne HeyerickRichard B Van Breemen et al.

A1 Journal Article in MOLECULAR NUTRITION & FOOD RESEARCH

Disposition of soy isoflavones in normal human breast tissue

Selin BolcaMireia Urpi-SardaPhillip BlondeelNathalie RocheLynn VanhaeckeSam PossemiersNawaf Al-MaharikNigel BottingDenis De KeukeleireMarc Bracke et al.

A1 Journal Article in AMERICAN JOURNAL OF CLINICAL NUTRITION

Effect of the secretory small GTPase Rab27B on breast cancer growth, invasion, and metastasis

An HendrixDawn MaynardPatrick PauwelsGeert BraemsHannelore DenysRudy Van den BroeckeJo LambertSimon Van BelleVeronique CocquytChristian Gespach et al.

A1 Journal Article in JOURNAL OF THE NATIONAL CANCER INSTITUTE

Extracellular cleavage and shedding of P-cadherin: a mechanism underlying the invasive behaviour of breast cancer cells

AS RibeiroA AlbergariaB SousaAL CorreiaMarc BrackeR SerucaFC SchmittJ Paredes

A1 Journal Article in ONCOGENE

From clinical observations of intensity-modulated radiotherapy to dedicated in vitro designs

Stéphanie BlockhuysBarbara VanhoeckeCarlos De WagterMarc BrackeWilfried De Neve

A1 Journal Article in MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells

Mathieu BoissanOlivier De WeverFloria LizarragaDominique WendumRenaud PoinclouxNicolas ChignardChristele Desbois-MouthonSylvie DufourBeatrice Nawrocki-RabyPhilippe Birembaut et al.

A1 Journal Article in CANCER RESEARCH

Modeling and quantification of cancer cell invasion through collagen type I matrices

Olivier De WeverAn HendrixAstrid De BoeckWendy WestbroekGeert BraemsShahin EmamiMichèle SabbahChristian GespachMarc Bracke

A1 Journal Article in INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Opioids affect focal contact-mediated cell-substrate adhesion

Delphine DebruyneMarcus MareelMarc Bracke

A1 Journal Article in EUROPEAN JOURNAL OF CANCER PREVENTION

P-cadherin counteracts myosin II-B function : implications in melanoma progression

Koen JacobsMireille Van GeleRamses ForsythLieve BrochezBarbara VanhoeckeOlivier De WeverMarc Bracke

A1 Journal Article in MOLECULAR CANCER

Resident and bone marrow-derived mesenchymal stem cells in head and neck squamous cell carcinoma

Astrid De BoeckKishan NarineWilfried De NeveMarcus MareelMarc BrackeOlivier De Wever

A1 Journal Article in ORAL ONCOLOGY

The NF-κB inhibitor IκBα negates colon cancer cell migration, invasion, proliferation and tumor growth

Samir AttoubRabah IratniSuhail Al-SalamKhouloud ArafatMAH Al SultanNadia Al MarzouqiEric BruyneelMarc BrackeOlivier De WeverChristian Gespach

A2 Journal Article in JOURNAL OF MEDICAL SCIENCES (BENTHAM)

The flavonoid tangeretin activates the unfolded protein response and synergizes with imatinib in the erythroleukemia cell line K562

Sofie LustBarbara VanhoeckeMireille Van GeleJan PhilippéMarc BrackeFritz Offner

A1 Journal Article in MOLECULAR NUTRITION & FOOD RESEARCH

The role of myofibroblasts in communicating tumor ecosystems

Olivier De WeverAstrid De BoeckPieter DemetterMarcus MareelMarc Bracke

Bookchapter in Tumor-associated fibroblasts and their matrix

The secretory GTPase RAB27b drives poor prognosis in ER alpha-positive breast cancer

An HendrixHannelore DenysGeert BraemsPatrick PauwelsRudy Van den BroeckeVeronique CocquytWendy WestbroekMarc BrackeOlivier De Wever

The secretory small GTPase Rab27B as a marker for breast cancer progression

An HendrixGeert BraemsMarc BrackeMiguel C SeabraWilliam A GahlOlivier De WeverWendy Westbroek

A1 Journal Article in ONCOTARGET

Transport of hop bitter acids across intestinal Caco-2 cell monolayers

Ko CattoorMarc BrackeDieter DeforceDenis De KeukeleireArne Heyerick

A1 Journal Article in JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

2009

A prospective, randomized, double-blind, placebo-controlled study on the use of a standardized hop extract to alleviate menopausal discomforts

Alvin IbarraSophie LafayArne HeyerickStefaan VervarckeHerman DepypereMarc BrackeDenis De Keukeleire

Antitumor Activity of the Selective MDM2 Antagonist Nutlin-3 Against Chemoresistant Neuroblastoma With Wild-Type p53

Tom Van MaerkenLiesbeth FerdinandeJasmien TaildemanIrina LambertzNurten YigitLiesbeth VercruysseAli RihaniMartin MichaelisJindrich CinatlClaude Cuvelier et al.

A1 Journal Article in JOURNAL OF THE NATIONAL CANCER INSTITUTE

Cell aggregation on agar as an indicator for cell-matrix adhesion: effects of opioids

Delphine DebruyneMarcus MareelBarbara VanhoeckeMarc Bracke

A1 Journal Article in IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Clinical markers and driving mechanism in melanoma progression: VEGF-C, RhoC, c-Ski/SnoN and EGFR

Barbara BooneLieve BrochezMarc Bracke

Cosupplementation of isoflavones, prenylflavonoids, and lignans alters human exposure to phytoestrogen-derived 17beta-estradiol equivalents

Selin BolcaCiska WynsSam PossemiersHerman DepypereDenis De KeukeleireMarc BrackeWilly VerstraeteArne Heyerick

A1 Journal Article in JOURNAL OF NUTRITION

Development of in vitro models for investigating spatially fractionated irradiation: physics and biological results

Stéphanie BlockhuysBarbara VanhoeckeLeen PaelinckMarc BrackeCarlos De Wagter

A1 Journal Article in PHYSICS IN MEDICINE AND BIOLOGY

Down-regulation of myopodin expression reduces invasion and motility of PC-3 prostate cancer cells

Ariane De GanckVEERLE DE CORTEErik BruyneelMarc BrackeJoël VandekerckhoveJan Gettemans

A1 Journal Article in INTERNATIONAL JOURNAL OF ONCOLOGY

In vitro cytotoxicity of paclitaxel/β-cyclodextrin complexes for HIPEC

Wim Bouquet-GeerardynTom BoterbergWim CeelenPiet PattynMarc PeetersMarc BrackeJean Paul RemonChris Vervaet

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS

Microbial activation of mixtures of isoflavones, prenylflavonoids and lignans

Selin BolcaEllen EeckhautArne HeyerickDenis De KeukeleireHerman DepypereMarc BrackeTom Van de WieleWilly Verstraete

Microbial and dietary factors associated with the Equol and 8-prenylnaringenin producer phenotypes

Selin BolcaSam PossemiersWilly VerstraeteTom Van de WieleArne HeyerickDenis De KeukeleireInge HuybrechtsStefaan De HenauwHerman DepypereMarc Bracke

Peritoneal minimal residual disease in colorectal cancer: mechanisms, prevention, and treatment

Wim CeelenMarc Bracke

A1 Journal Article in LANCET ONCOLOGY

Steroid effects on ZAP-70 and SYK in relation to apoptosis in poor prognosis chronic lymphocytic leukemia

Jerina BoelensSofie LustFemke Van BockstaeleMireille Van GeleAnn JanssensLara DeryckeBarbara VanhoeckeJan PhilippéMarc BrackeFritz Offner

A1 Journal Article in LEUKEMIA RESEARCH

Synthesis, biological evaluation and 2D-QSAR analysis of chalcones as anti-invasive cancer agents

Bart RomanChristian StevensBarbara VanhoeckeMarc Bracke

TRIP6, a novel molecular partner of the MAGI-1 scaffolding molecule, promotes invasiveness

Eric ChastreMahmoud AbdessamadAlexey KruglovErik BruyneelMarc BrackeYolande Di GioiaMary C. BeckerleFrans Van RoyLarissa Kotelevets

A1 Journal Article in FASEB JOURNAL

The extracellular matrix regulates cancer progression and therapy response: implications for prognosis and treatment

Hannelore DenysGeert BraemsKathleen LambeinPatrick PauwelsAn HendrixAstrid De BoeckVeronique MathieuMarc BrackeOlivier De Wever

A1 Journal Article in CURRENT PHARMACEUTICAL DESIGN

The secretory small GTPase Rab27B regulates invasive tumor growth and metastasis through extracellular heat shock protein 90 alpha

An HendrixD MaynardP PauwelsG BraemsHannelore DenysRudy Van den BroeckeSimon Van BelleVeronique CocquytMarc BrackeM Seabra et al.

Xanthohumol activates the proapoptotic arm of the unfolded protein response in chronic lymphocytic leukemia

Sofie LustBarbara VanhoeckeMireille Van GeleJerina BoelensHeleen Van MelckebekeMary KailehWim Vanden BergheGuy HaegemanJan PhilippéMarc Bracke et al.

A1 Journal Article in ANTICANCER RESEARCH

2008

Antioxidant, antiinflammatory and antiinvasive activities of biopolyphenolics

Malhotra ShashwatGaurav ShakyaAjit KumarBarbara VanhoeckeAshok L CholliHanumantharao G RajLuciano SasoBalaram GhoshMarc BrackeAshok K Prasad et al.

A1 Journal Article in ARKIVOC

Autocrine induction of invasion and metastasis by tumor-associated trypsin inhibitor in human colon cancer cells

V GOUYERD FONTAINEPieter DumontOlivier De WeverH FONTAYNE-DEVAUDE LETEURTRES TRUANTD DELACOURH DROBECQJP KERCKAERT et al.

A1 Journal Article in ONCOGENE

Cellular uptake of soy-derived phytoestrogens in vitro and in human whole blood

Julie MaubachMarc BrackeHerman DepypereDenis De KeukeleireArne Heyerick

A2 Journal Article in Journal of Pre-Clinical and Clinical Research

Differential impact of TGF-β and EGF on fibroblast differentiation and invasion reciprocally promotes colon cancer cell invasion

Hannelore DenysLara DeryckeAn HendrixWendy WestbroekAlexander GheldofKishan NarinePatrick PauwelsChristian GespachMarc BrackeOlivier De Wever

A1 Journal Article in CANCER LETTERS

Enhancement of PDGF-BB mitogenic activity on human dermal fibroblasts by biospecific dextran derivatives

AS VERCOUTTER-EDOUARTG DUBREUCQBarbara VanhoeckeC RIGAUTF RENAUXL DAHRI-CORREIAJ LEMOINEMarc BrackeJC MICHALSKIJ CORREIA

A1 Journal Article in BIOMATERIALS

Molecular and pathological signatures of epithelial-mesenchymal transitions at the cancer invasion front

Olivier De WeverPatrick PauwelsBram De CraeneM SABBAHS EMAMIG REDEUILHC GESPACHMarc BrackeGeert Berx

A1 Journal Article in HISTOCHEMISTRY AND CELL BIOLOGY

Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers

Michele SabbahShahin EmamiGerard RedeuilhSylvia JulienGregoire PrevostAmazia ZimberRadia OuelaaMarc BrackeOlivier De WeverChristian Gespach

A1 Journal Article in DRUG RESISTANCE UPDATES

Plant polyphenolics as anti-invasive cancer agents

Marc BrackeBarbara VanhoeckeLara DeryckeSelin BolcaSam PossemiersArne HeyerickChristian StevensDenis De KeukeleireHerman DepypereWilly Verstraete et al.

A1 Journal Article in ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY

Pollutant effects on genotoxic parameters and tumor-associated protein levels in adults: a cross sectional study

Sam De CosterG KOPPENMarc BrackeC SCHROIJENE DEN HONDV NELENE VAN DE MIEROOPL BRUCKERSMaaike BilauWENDY BAEYENS et al.

A1 Journal Article in ENVIRONMENTAL HEALTH

Role of WISP-2/CCN5 in the maintenance of a differentiated and noninvasive phenotype in human breast cancer cells

A FRITAHC SAUCIEROlivier De WeverMarc BrackeI BIECHER LIDEREAUC GESPACHS DROUOTG REDEUILHM SABBAH

A1 Journal Article in MOLECULAR AND CELLULAR BIOLOGY

Stromal myofibroblasts are drivers of invasive cancer growth

Olivier De WeverPieter DemetterMarcus MareelMarc Bracke

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Synthesis, biological evaluation and 2D-QSAR analysis of chalcones as anti-invasive cancer agents

Bart RomanChristian StevensMarc BrackeBarbara Vanhoecke

Synthesis, biological evaluation and 2D-QSAR analysis of chalcones as anti-invasive cancer agents

Bart RomanChristian StevensMarc BrackeBarbara Vanhoecke

The microbial PhIP metabolite 7-hydroxy-5-methyl-3-phenyl-6,7,8,9-tetrahydropyrido[3 ',2 ': 4,5]imidazo[1,2-a]pyrimidin-5-ium chloride (PhIP-M1) induces DNA damage, apoptosis and cell cycle arrest towards Caco-2 cells

Lynn VanhaeckeLara DeryckeF LE CURIEUXSofie LustD MARZINWilly VerstraeteMarc Bracke

A1 Journal Article in TOXICOLOGY LETTERS

The prenylated chalcone xanthohumol induces unfolded protein response, autophagy, and cell death in breast cancer cells by proteasome inhibition

Barbara VanhoeckeMireille Van GeleWim MartinetAnne-Sophie Vercoutter-EdouartSofie LustDelphine DebruyneDenis De KeukeleireFritz OffnerMarc Bracke

2007

A possible mechanism of peritoneal pH changes during carbon dioxide pneumoperitoneum

OA MYNBAEVPR KONINCKXMarc Bracke

A possible mechanism of peritoneal pH changes during carbon dioxide pneumoperitoneum

O.A. MynbaevL. DolleMarc Bracke

A1 Journal Article in SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES

Akt1 & 2 depletion by RNA interference reduced tumor growth and invasion in human colon cancer cells

A GABONOlivier De WeverErik BruyneelMarc BrackeC GESPACHS ATTOUB

Cell motility and breast cancer metastasis.

Marc BrackeDaan De MaeseneerVeerle Van MarckLara DeryckeBarbara VanhoeckeOlivier De WeverHerman Depypere

Bookchapter in Metastasis of Breast Cancer.

Downregulation of gelsolin family proteins counteracts cancer cell invasion in vitro

A VAN DEN ABBEELEVeerle De CorteKatrien Van ImpeErik BruyneelC BOTTCHERIEMarc BrackeJoël VandekerckhoveJan Gettemans

A1 Journal Article in CANCER LETTERS

Estrogen receptor alpha (ER alpha) and insulin-like growth factor I receptor (IGF-IR) cross-talk in the gonadotropic alpha T3-1 cell line

F EertmansWillem DhoogeOlivier De WeverMarc BrackeFrank ComhaireJean Kaufman

A1 Journal Article in JOURNAL OF CELLULAR PHYSIOLOGY

Estrogen receptor signaling is an unstable feature of the gonadotropic LβT2 cell line

F EertmansWillem DhoogeOlivier De WeverWim Vanden BergheVeerle BogaertMarc BrackeGuy HaegemanFrank ComhaireJean Kaufman

A1 Journal Article in MOLECULAR AND CELLULAR ENDOCRINOLOGY

Intestinal bacteria play a crucial role in the carcinogenic risk from 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

Lynn VanhaeckeMG KNIZELara DeryckeF LE CURIEUXMarc BrackeWilly Verstraete

Lipoplex-loaded microbubbles for gene delivery: A Trojan horse controlled by ultrasound

Ine LentackerStefaan De SmedtJo DemeesterVeerle Van MarckMarc BrackeNiek Sanders

A1 Journal Article in ADVANCED FUNCTIONAL MATERIALS

Microbial and dietary factors are associated with the equol producer phenotype in healthy postmenopausal women

Selin BolcaSam PossemiersAnnelies HerregatInge HuybrechtsArne HeyerickStephanie De VrieseMarian VerbruggenHerman DepypereDenis De KeukeleireMarc Bracke et al.

A1 Journal Article in JOURNAL OF NUTRITION

Microbial and dietary factors associated with the 8-prenylnaringenin producer phenotype: a dietary intervention trial with fifty healthy post-menopausal Caucasian women

Selin BolcaSam PossemiersVeerle MaervoetInge HuybrechtsArne HeyerickStefaan VervaeckeHerman DepypereDenis De KeukeleireMarc BrackeStefaan De Henauw et al.

A1 Journal Article in BRITISH JOURNAL OF NUTRITION

Microbial and dietary factors associated with the equaol and 8-prenylnaringenin poducer phenotypes

Selin BolcaSam PossemiersArne HeyerickInge HuybrechtsHerman DepypereDenis De KeukeleireMarc BrackeStefaan De HenauwWilly VerstraeteTom Van de Wiele

QSAR directed design, synthesis and evaluation of anti-invasive chalcones and related heterocyclic compounds

Bart RomanChristian StevensMarc BrackeBarbara Vanhoecke

Role of adhesion molecules in locoregional cancer spread.

Bookchapter in Peritoneal carcinomatosis : A Multidisciplinary Approach.

Soluble cadherins as cancer biomarkers

Olivier De WeverLara DeryckeAn HendrixGert De MeerleerF GODEAUHerman DepypereMarc Bracke

A1 Journal Article in CLINICAL & EXPERIMENTAL METASTASIS

The anti-invasive and proapoptotic effect of xanthohumol: potential use in cancer.

Barbara VanhoeckeJERINA BOELENSSofie LustFritz OffnerMarc Bracke

Bookchapter in Beer in Health and Desease Prevention

The endoplasmic reticulum: A target for new anticancer drugs

Jerina BoelensSofie LustFritz OffnerMarc BrackeBarbara Vanhoecke

A1 Journal Article in IN VIVO

The tandem PDZ domains of syntenin promote cell invasion

Kris Meerschaert.krErik BruyneelOlivier De WeverBerlinda VanlooCiska BoucherieMarc BrackeJoël VandekerckhoveJan Gettemans

A1 Journal Article in EXPERIMENTAL CELL RESEARCH

Xanthohumol induces in vitro apoptosis in B-CLL cells mediated by non-classical ER stress

Sofie LustBarbara VanhoeckeMireille Van GeleJerina BoelensMary KailehWim Vanden BergheJ PHILLIPESMarc BrackeFritz Offner

Xanthohumol: a new potential proteasome inhibitor that activates the pro-apoptotic arm of the unfolded protein response in B-CLL cells

Sofie LustBarbara VanhoeckeMireille Van GeleJerina BoelensJan PhilippéPetra VinckenMarc BrackeMartine PoelmanFritz Offner

2006

A first prospective, randomized, double-blind, placebo-controlled study on the use of a standardized hop extract to alleviate menopausal discomforts

Arne HeyerickS VERVARCKEHerman DepypereMarc BrackeDenis De Keukeleire

A1 Journal Article in MATURITAS

ARE PHYTOESTROGENS OF ANY HELP

Herman DepypereMarc BrackeBarbara VanhoeckeDenis De KeukeleireArne HeyerickSelin BolcaWilly Verstraete

Anti-invasive and anti-metastasis strategies: New roads, new tools and new hopes

L DOLLEHerman DepypereMarc Bracke

A1 Journal Article in CURRENT CANCER DRUG TARGETS

Anticancer activity of BIM-46174, a new inhibitor of the heterotrimeric G alpha/G beta gamma protein complex

GP PREVOSTMO LONCHAMPTS HOLBECKS ATTOUBD ZAHAREVITZM ALLEYJ WRIGHTMC BREZAKH COULOMBA SAVOLA et al.

A1 Journal Article in CANCER RESEARCH

Bioavailability of phytoestrogens from soy and hops

Selin BolcaSam PossemiersArne HeyerickDenis De KeukeleireHerman DepypereMarc BrackeInge HuybrechtsStefaan De HenauwWilly Verstraete

Colon cancer cells: pro-invasive signalling

Delphine DebruyneMaria José OliveiraMarc BrackeMarcus MareelAncy Leroy

A1 Journal Article in INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Differences in tumor-associated protein levels among middle-age Flemish women in association with area of residence and exposure to pollutants

Nicolas Van LarebekeMarc BrackeV NELENG KOPPENG SCHOETERSH VAN LOONR VLIETINCK

A1 Journal Article in ENVIRONMENTAL HEALTH PERSPECTIVES

Exploring the 8-PN producer phenotype: an intervention trial with 50 healthy post-menopausal Caucasian women

Selin BolcaSam PossemiersVeerle MaervoetArne HeyerickDenis De KeukeleireHerman DepypereMarc BrackeInge HuybrechtsTom Van de WieleWilly Verstraete

Exploring the equol producer phenotype: an intervention trial with 100 healthy post-menoapausal Caucasian women

Selin BolcaSam PossemiersAnnelies HerregatArne HeyerickDenis De KeukeleireHerman DepypereMarc BrackeInge HuybrechtsStefaan De HenauwTom Van de Wiele et al.

Growth factor modulation of fibroblast proliferation, differentiation, and invasion: Implications for tissue valve engineering

K NARINEOlivier De WeverDillis Van ValckenborghKatrien FrancoisMarc BrackeStefaan De SmetMarcus MareelGuido Van Nooten

A1 Journal Article in TISSUE ENGINEERING

Induction of the adenoma-carcinoma progression and Cdc25A-B phosphatases by the trefoil factor TFF1 in human colon epithelial cells

S RODRIGUESCM RODRIGUES ATTOUBJF FLEJOUErik BruyneelMarc BrackeS EMAMIC GESPACH

A1 Journal Article in ONCOGENE

QSAR modeling of anti-invasive activity of organic compounds using structural descriptors

AR KATRITZKYM KUANARDA DOBCHEVBarbara VanhoeckeM KARELSONVS PARMARChristian StevensMarc Bracke

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

Soluble N-cadherin fragment promotes angiogenesis

Lara DeryckeL MORBIDELLIM ZICHEOlivier De WeverMarc BrackeElisabeth Van Aken

A1 Journal Article in CLINICAL & EXPERIMENTAL METASTASIS

Soluble N-cadherin in human biological fluids

Lara DeryckeOlivier De WeverVeronique StoveBarbara VanhoeckeJoris DelangheHerman DepypereMarc Bracke

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

The extracellular fragment of N-cahderin stimulates angiogenesis and migration and invasion of cells

Lara DeryckeElisabeth Van AkenMarc Bracke

Tibolone and its metabolites inhibit invasion of human mammary carcinoma cells in vitro

Barbara VanhoeckeMarc BrackeHJ KLOOSTERBOERHerman Depypere

A1 Journal Article in MATURITAS

Tumour markers in andrology

Bookchapter in Andrology for the Clinician

2005

A proteomic approach to understand the anti-invasive and pro-apoptotic effect of xanthohumol in human breast cancer cells

Barbara VanhoeckeLaurent DolleA Vercoutter-EdouartJ AntolHerman DepypereMarc Bracke

A safety study of oral tangeretin and xanthohumol administration to laboratory mice

Barbara VanhoeckeFEMKE DELPORTEEva Van BraeckelArne HeyerickHerman DepypereM NUYTINCKDenis De KeukeleireMarc Bracke

A1 Journal Article in IN VIVO

Antiinvasive effect of xanthohumol, a prenylated chalcone present in hops (Humulus lupulus L.) and beer

Barbara VanhoeckeLara DeryckeV VAN MARCKHerman DepypereDenis De KeukeleireMarc Bracke

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Bowes melanoma cells secrete heregulin, which can promote aggregation and counteract invasion of human mammary cancer cells

Christophe StoveTom BoterbergVeerle Van MarckMarcus MareelMarc Bracke

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Commutators of PAR-1 signaling in cancer cell invasion reveal an essential role of the Rho-Rho kinase axis and tumor microenvironment

QD NGUYENOlivier De WeverErik BruyneelAn HendrixWZ XIEA LOMBETM LEIBLMarcus MareelF GIESELERMarc Bracke et al.

A1 Journal Article in ONCOGENE

Epithelial-mesenchymal transitions in human cancer

Veerle Van MarckMarc Bracke

Bookchapter in Rise and fall of Epithelial Phenotype : concepts of Epithelial-Mesenchymal transition

Molecular targets of growth, differentiation, tissue integrity, and ectopic cell death in cancer cells

Lara DeryckeVeerle Van MarckHerman DepypereMarc Bracke

A1 Journal Article in CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Nerve Growth Factor mediates its pro-invasive effect in parallel with the release of a soluble E-cadherin fragment from breast cancer MCF-7/AZ cells

L DOLLEMJ OLIVEIRAErik BruyneelH HONDERMARCKMarc Bracke

A1 Journal Article in JOURNAL OF DAIRY RESEARCH

New anti-invasive compounds: Results from the Indo-Belgian screening program

Barbara VanhoeckeHerman DepypereA DE BEYTERSK SHARMAVS PARMARDenis De KeukeleireMarc Bracke

A1 Journal Article in PURE AND APPLIED CHEMISTRY

P-cadherin promotes cell-cell adhesion and counteracts invasion in human melanoma

Veerle Van MarckChristophe StoveKarolien Van Den BosscheVeronique StoveJoana ParedesYves Vander HaeghenMarc Bracke

A1 Journal Article in CANCER RESEARCH

STAT3, TFF3, VEGFR in colon cancer cells (vol 65, pg 165, 2005)

C RIVATS RODRIGUESErik BruyneelG PIETUA ROBERTG REDEUILHMarc BrackeC GESPACHS ATTOUB

Tangeretin inhibits extracellular-signal-regulated kinase (ERK) phosphorylation

S VAN SLAMBROUCKVS PARMARSK SHARMAB DE BONDTF FOREP COOPMANBarbara VanhoeckeTom BoterbergHerman DepypereGeorges Leclercq et al.

A1 Journal Article in FEBS LETTERS

The cancer chemopreventive agent resveratrol induces tensin, a cell-matrix adhesion protein with signaling and antitumor activities

CM RODRIGUEF PORTEUN NAVARROErik BruyneelMarc BrackePH ROMEOC GESPACHMC GAREL

A1 Journal Article in ONCOGENE

Tibolone and its metabolites inhibit invasion of human mammary carcinoma cells in vitro

Herman DepypereMarc BrackeBarbara VanhoeckeHJ KLOOSTERBOER

Unrecognized or potential risk factors for childhood cancer

Nicolas Van LarebekeLS BIRNBAUMMA BOOGAERTSMarc BrackeDL DAVISDM DEMARINIK HOOPERJ HUFFJC KLEINJANSMS LEGATOR et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH

Xanthohumol induces apoptosis in B-CLL mediated by caspase 9 following downregulation of bcL-xL and mcl-1

Barbara VanhoeckeSofie LustAnne JanssensJan PhilippéMarc BrackeFritz Offner

Xanthohumol kills B-chronic lymphocytic leukemia cells by an apoptotic mechanism

Sofie LustBarbara VanhoeckeAnne JanssensJan PhilippéMarc BrackeFritz Offner

A1 Journal Article in MOLECULAR NUTRITION & FOOD RESEARCH

2004

A reproducible animal model of colon cancer with a solitary neoplastic growth

M El-MaltPieter DemetterWim CeelenClaude CuvelierMarc BrackeBernard de HemptinnePiet PattynLuc Vakaet

A road map for cancer invasion : implication of myofibroblasts and other factors

Olivier De WeverMarc BrackeMarcus Mareel

Alpha-catenin is required for IGF-I-induced cellular migration but not invasion in human colonic cancer cells

F ANDRÉBarbara JanssensErik BruyneelFrans Van RoyC GESPACHMarcus MareelMarc Bracke

A1 Journal Article in ONCOGENE

CXCL-12 induces prolonged erk-phosphorylation in Zap-70 positive B-CLL

Sofie LustJerina BoelensANN JANSSENSJan PhilippéMarc BrackeFritz Offner

Cellular activities related to growth and invasion: targets for flavonoids

Barbara VanhoeckeHerman DepypereDenis De KeukeleireMarc Bracke

Bookchapter in Recent research developments in cell science

Critical role of N-cadherin in myofibroblast invasion and migration in vitro stimulated by colon-cancer-cell-derived TGF-beta or wounding

Olivier De WeverWendy WestbroekA VERLOESN BLOEMENMarc BrackeC GESPACHErik BruyneelMarcus Mareel

A1 Journal Article in JOURNAL OF CELL SCIENCE

Distribution of soy-derived phytoestrogens in human breast tissue and biological fluids

J MAUBACHHerman DepypereJan GoemanJohan Van der EyckenArne HeyerickMarc BrackePhillip BlondeelDenis De Keukeleire

A1 Journal Article in OBSTETRICS AND GYNECOLOGY

Dual activities of galectin-3 in human prostate cancer: tumor suppression of nuclear galectin-3 vs tumor promotion of cytoplasmic galectin-3

S CALIFICEV CASTRONOVOMarc BrackeF VAN DEN BRULE

A1 Journal Article in ONCOGENE

Melanoma cells secrete follistatin, an antagonist of activin-mediated growth inhibition

Christophe StoveFrank VanrobaeysBart DevreeseJozef Van BeeumenMarcus MareelMarc Bracke

A1 Journal Article in ONCOGENE

N-cadherin in the spotlight of cell-cell adhesion, differentiation, embryogenesis, invasion and signalling

Lara DeryckeMarc Bracke

A1 Journal Article in INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Oestrogen-mediated regulation of somatostatin receptor expression in human breast cancer cell lines assessed with Tc-99m-depreotide

Bieke Van Den BosscheE D'HAENINCKFilip De VosRudi DierckxSimon Van BelleMarc BrackeChristophe Van De Wiele

A1 Journal Article in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

P-cadherin is up-regulated by the antiestrogen ICI 182,780 and promotes invasion of human breast cancer cells

Joana ParedesChristophe StoveVeronique StoveFernanda MilaneziVeerle Van MarckLara DeryckeMarcus MareelMarc BrackeFernando Schmitt

A1 Journal Article in CANCER RESEARCH

Roles for neuregulins in human cancer

Christophe StoveMarc Bracke

A1 Journal Article in CLINICAL & EXPERIMENTAL METASTASIS

Soluble N-cadherin fragments: a new indicator of invasion. Vol. 59(2)

Lara DeryckeChristophe StoveMarieke GoossensVeerle Van MarckMarc Bracke

Tangeretin synergizes with imatinib in inhibiting growth of bcr-abl positive K562 Erythroleukemia cells in an Erk-dependent way

Sofie LustBarbara VanhoeckeMarc BrackeFritz Offner

Tenascin-C and SF/HGF produced by myofibroblasts in vitro provide convergent proinvasive signals to human colon cancer cells through RhoA and Rac

Olivier De WeverQD NGUYENLeen Van HoordeMarc BrackeErik BruyneelC GESPACHMarcus Mareel

A1 Journal Article in FASEB JOURNAL

The effect of bacteria on colon cancer cell invasion : molecular mechanisms associated

Maria José OliveiraMarc BrackeAncy Leroy

2003

New monoclonal antibodies for human N-cadherin.

Lara DeryckeChristophe StoveMarcus MareelMarc Bracke

Quantitation of soy-derived phytoestrogens in human breast tissue and biological fluids by high-performance liquid chromatography

J MAUBACHMarc BrackeArne HeyerickHerman DepypereRudolphe SerreynMarcus MareelDenis De Keukeleire

A1 Journal Article in JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Role of the IGF-I receptor in the regulation of cell-cell adhesion: Implications in cancer development and progression

L MAUROM SALERNOC MORELLITom BoterbergMarc BrackeE SURMACZ

A1 Journal Article in JOURNAL OF CELLULAR PHYSIOLOGY

SP-06 A new clue for the resistance of malignant melanoma? Follistatin secretion overcomes activin-mediated growth inhibition

Christophe StoveFrank VanrobaeysBart DevreeseJozef Van BeeumenMarcus MareelMarc Bracke

Synthesis of novel heterocyclic compounds: Routes to pyrazolyl 1,2,3-triazoles and their biological activity evaluation

A KUMARM HUSAINAK PRASADI SINGHA VATSNK SHARMASK SHARMARK GUPTACE OLSENMarc Bracke et al.

A1 Journal Article in INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY

Synthesis, characterization and in vitro anti-invasive activity screening of polyphenolic and heterocyclic compounds

VS PARMARNK SHARMAM HUSAINAC WATTERSONJ KUMARLA SAMUELSONAL CHOLLIAK PRASADS MALHOTRAN KUMAR et al.

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

The heregulin/human epidermal growth factor receptor as a new growth factor system in melanoma with multiple ways of deregulation

Christophe StoveVeronique StoveLara DeryckeVeerle Van MarckMarcus MareelMarc Bracke

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

2002

8-prenylnaringenin, the phytooestrogen in hops and beer, may influence the incidence of breast cancer.

Herman DepypereH RONGTom BoterbergR SERREYNChristophe StoveSABINE VAN SLAMBROUCKDenis De KeukeleireMarcus MareelMarc Bracke

Applications en cancérologie

F ANDRÉMarc BrackeMarcus Mareel

Bookchapter in Cultures de Cellules Animales

Cell aggregation assays

Tom BoterbergMarc BrackeErik BruyneelMarcus Mareel

Bookchapter in Metastasis research protocols, volume II : analysis of cell behavior in vitro and in vivo

Chick heart invasion assay

Marc BrackeTom BoterbergMarcus Mareel

Bookchapter in Metastasis research protocols, volume II : analysis of cell behavior in vitro and in vivo

Collagen invasion assay

Marc BrackeTom BoterbergErik BruyneelMarcus Mareel

Bookchapter in Metastasis research protocols, volume II : analysis of cell behavior in vitro and in vivo

Downregulation in vivo of the invasion-suppressor molecule E-cadherin in experimental and clinical cancer

Marcus MareelK VLEMINCKXS VERMEULENG YANMarc BrackeFrans Van Roy

Effects of tangeretin on human cell-cell interactions

Marc BrackeTom BoterbergHerman DepypereChristophe StoveGeorges LeclercqG VandecasteeleMarcus Mareel

Evaluation de substances anti-invasives en culture organotypique

Marcus MareelMarc BrackeErik BruyneelNicolas Van LarebekeMarc De Mets

Inhibitory effect of different flavonoids on the invasion of malignant MO4 cells into embryonic chick heart in vitro.

Marc BrackeR VAN CAUWENBERGEMarcus Mareel

Invasion assay using embryonic chick heart

Marc BrackeMarcus Mareel

Bookchapter in Cell and tissue culture : laboratory procedures, 5A

Investigation of tumour-invasion mechanisms.

Marcus MareelFrans Van RoyL MESSIAENMarc BrackeE BOGHAERTP COOPMAN

Modulation of invasion in vitro and in vivo

Marcus MareelK VLEMINCKXY GAONicolas Van LarebekeMarc BrackeFrans Van Roy

Molecular mechanisms of cancer invasion

Marcus MareelMarc Bracke

Plasmin produces an E-cadherin fragment that stimulates cancer cell invasion.

F RYNIERSChristophe StoveM GOETHALSL BRACKENIERV NOEMarc BrackeJoël VandekerckhoveMarcus MareelErik Bruyneel

A1 Journal Article in BIOLOGICAL CHEMISTRY

The citrus methoxyflavone tangeretin affects human cell-cell interactions

Marc BrackeTom BoterbergHerman DepypereChristophe StoveGeorges LeclercqMarcus Mareel

A1 Journal Article in FLAVONOIDS IN CELL FUNCTION

2001

8-Prenylnaringenin, the phytoestrogen in hops and beer, upregulates the function of the E-cadherin/catenin complex in human mammary carcinoma cells

Haojing RongTom BoterbergJulie MaubachChristophe StoveHerman DepypereSeverine Van slambrouckRudolphe SerreynDenis De KeukeleireMarcus MareelMarc Bracke

A1 Journal Article in EUROPEAN JOURNAL OF CELL BIOLOGY

An anti-invasive factor in the conditioned medium of a melanoma cell line: signaling via the ErbB receptors?

Christophe StoveTom BoterbergLara DeryckeD VANDEKERKHOVEMarcus MareelMarc Bracke

Synthetic and biological activity evaluation studies on novel 1,3-diarylpropenones.

S MUKHERJEEW KUMARAK PRASADHG RAJMarc BrackeCE OLSENSC JAINVS PARMAR

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

2000

Inhibition of tamoxifen's therapeutic benefit by tangeretin in mammary cancer.

Herman DepypereMarc BrackeTom BoterbergMarcus MareelM NUYTINCKK VENNEKENSRudolphe Serreyn

A1 Journal Article in EUROPEAN JOURNAL OF CANCER

Internalization of the E-cadherin/catenin complex and scattering of human mammary carcinoma cells: MCF-7/AZ after treatment with conditioned medium from human skin squamous carcinoma cells COLO 16.

Tom BoterbergKM VENNEKENSM THIENPONTMarcus MareelMarc Bracke

A1 Journal Article in CELL ADHESION AND COMMUNICATION

Tangerine effects on human mammary cell interactions

Marc BrackeTom BoterbergGeorges LeclercqHerman DepypereMarcus Mareel

The E-cadherin/catenin complex in invasion: the role of ectodomain shedding.

V NOEErik BruyneelMarcus MareelMarc Bracke

Bookchapter in Cancer Metastasis, Molecular and Cellular Mechanisms and Clinical Intervention

1999

Influence of tangeretin on tamoxifen's therapeutic benefit in mammary cancer.

Marc BrackeHerman DepypereTom BoterbergVeerle Van MarckKM VENNEKENSE VANLUCHENEM NUYTINCKRudolphe SerreynMarcus Mareel

A1 Journal Article in JOURNAL OF THE NATIONAL CANCER INSTITUTE

The αE-catenin gene (CTNNA1) acts as an invasion-suppressor gene in human colon cancer cells

Stefan VermeulenFriedel NolletE TEUGELSKM VENNEKENSFransiska MalfaitJan PhilippéFranki SpelemanMarc BrackeFrans Van RoyMarcus Mareel

A1 Journal Article in ONCOGENE

1998

Cellular and molecular mechanisms of metastasis as applied to carcinomatous meningitis.

Marcus MareelAncy LeroyMarc Bracke

A1 Journal Article in JOURNAL OF NEURO-ONCOLOGY

1997

Activation and inactivation of invasion-suppressor molecules : in vitro analysis

Marcus MareelStefan VermeulenV. NoëLeen Van HoordeErik BruyneelFrans Van RoyMarc Bracke

Bookchapter in Forschung ohne Tierversuche 1996

Anti-invasive activity of alkaloids and polyphenolics in vitro.

VS PARMARMarc BrackeJan PhilippéJ WENGELSC JAINCE OLSENKS BISHTNK SHARMAA COURTENSSK SHARMA et al.

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

E-cadherin/catenin/cytoskeleton complex: a regulator of cancer invasion

Marcus MareelTom BoterbergV NOELeen Van HoordeStefan VermeulenErik BruyneelMarc Bracke

A1 Journal Article in JOURNAL OF CELLULAR PHYSIOLOGY

Functional downregulation of the E-cadherin/catenin complex leads to loss of contact inhibition of motility and of mitochondrial activity, but not of growth in confluent epithelial cell cultures

Marc BrackeHerman DepypereC LabitVeerle Van MarckK VennekensSJ VermeulenI MaelfaitJan PhilippéRudolphe SerreynMarcus Mareel

A1 Journal Article in EUROPEAN JOURNAL OF CELL BIOLOGY

Metastasis to the brain: cellular and molecular mechanisms

Marcus MareelAncy LeroyMarc Bracke

Bookchapter in Neuro-oncology, part 3 : neurological disorders in systemic cancer

Moleculaire mechanismen van kankeruitzaaiing: adhesie moleculen en netwerken van signaaltransductie

Marcus MareelStefan VermeulenMarc Bracke

A4 Journal Article in VERHANDELINGEN VAN DE KONINKLIJKE ACADEMIE VOOR GENEESKUNDE VAN BELGIË

Mutation of alpha-catenin results in invasiveness of human HCT-8 colon cancer cells.

SJ VERMEULENF NOLLETE TEUGELSJan PhilippéFranki SpelemanFrans Van RoyMarc BrackeMarcus Mareel

A1 Journal Article in ANNALS OF THE NEW YORK ACADEMY OF SCIENCES

Regulatie van het invasiesuppressor E-cadherine/catenine complex in humane kankercellen

Stefan VermeulenMarc BrackeM. Mareel

1996

Anti-invasive therapy: manipulation of the E-cadherin/catenin/cytoskeleton complex

Marcus MareelV NOEStefan VermeulenMarc Bracke

Cadherin/catenin complex: A target for antiinvasive therapy?

Marcus MareelGeert BerxFrans Van RoyMarc Bracke

A1 Journal Article in JOURNAL OF CELLULAR BIOCHEMISTRY

Enhancement of tamoxifen-induced E-cadherin function by Ca2+ channel antagonists in human breast cancer MCF7/6 cells.

C CHARLIERErik BruyneelC LECHANTEURMarc BrackeMarcus MareelV CASTRONOVO

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACOLOGY

Regulation of the invasion suppressor function of the cadherin/catenin complex

Stefan VermeulenVeerle Van MarckLeen Van HoordeFrans Van RoyMarc BrackeMarcus Mareel

A2 Journal Article in Path. Res. Pract., 192

Regulation of the invasion suppressor function of the cadherin/catenin complex.

S VERMEULENV VANMARCKL VANHOORDEFrans Van RoyMarc BrackeMarcus Mareel

A1 Journal Article in PATHOLOGY RESEARCH AND PRACTICE

Tamoxifen and the E-cadherin/catenin complex.

Marc BrackeFrans Van RoyV CASTRONOVOMarcus Mareel

Bookchapter in Tamoxifen : Beyond the Antiestrogen

The E-cadherin/catenin complex in invasion and metastasis

Marc BrackeFrans Van RoyMarcus Mareel

Bookchapter in Attempts to understand metastasis formation I : metastasis-related molecules

The E-cadherin/catenin complex in invasion and metastasis.

Marc BrackeFrans Van RoyMarcus Mareel

A1 Journal Article in CURRENT TOPICS IN MICROBIOLOGY AND IMMUNOLOGY

The cadherin/catenin complex: a target for antiinvasive therapy ?

Marcus MareelGeert BerxFrans Van RoyMarc Bracke

A2 Journal Article in Journal Cellular Biochem., 61

The cadherin/catenin complex: a target for therapy

Marcus MareelStefan VermeulenV NoëL Van HoordeMarc Bracke

1995

ACTIVATION OF THE E-CADHERIN/CATENIN COMPLEX IN HUMAN MCF-7 BREAST-CANCER CELLS BY ALL-TRANS-RETINOIC ACID

Stefan VermeulenErik BruyneelFrans Van RoyMarcus MareelMarc Bracke

A1 Journal Article in BRITISH JOURNAL OF CANCER

CANCER METASTASIS - NEGATIVE REGULATION BY AN INVASION-SUPPRESSOR COMPLEX

Marcus MareelMarc BrackeFrans Van Roy

A1 Journal Article in CANCER DETECTION AND PREVENTION

HETEROTRANSPLANTATION OF PRIMARY AND ESTABLISHED HUMAN TUMOR-CELLS IN NUDE-MICE.

A NOELV BORCYMarc BrackeC GILLESJ BERNARDP BIREMBAUTMarcus MareelJM FOIDART

A1 Journal Article in ANTICANCER RESEARCH

Novel function for all-trans-retinoic acid: induction of adhesive function of E-cadherin in human cancer cells

Stefan VermeulenErik BruyneelFrans Van RoyMarc BrackeMarcus Mareel

A1 Journal Article in CELL BIOLOGY INTERNATIONAL

REMOVAL OF SIALIC-ACID FROM THE SURFACE OF HUMAN MCF-7 MAMMARY-CANCER CELLS ABOLISHES E-CADHERIN-DEPENDENT CELL-CELL ADHESION IN AN AGGREGATION ASSAY.

Joris DemanNA VANLAREBEKEErik BruyneelMarc BrackeStefan VermeulenKM VENNEKENSMarcus Mareel

A1 Journal Article in IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Transition from the noninvasive to the invasive phenotype and loss of α-catenin in human colon cancer cells

Stefan VermeulenErik BruyneelMarc BrackeGeorges De BruyneKrist'l M VennekensKris VleminckxGeert BerxFrans Van RoyMarcus Mareel

A1 Journal Article in CANCER RESEARCH

1994

ANTI-INVASIVE ACTIVITY OF 3,7-DIMETHOXYFLAVONE IN-VITRO.

VS PARMARR JAINSK SHARMAA VARDHANA JHAP TANEJAS SINGHBM VYNCKEMarc BrackeMarcus Mareel

A1 Journal Article in JOURNAL OF PHARMACEUTICAL SCIENCES

CITRUS FLAVONOID EFFECT ON TUMOR INVASION AND METASTASIS.

Marc BrackeErik BruyneelSJ VERMEULENK VENNEKENSV VANMARCKMarcus Mareel

A1 Journal Article in FOOD TECHNOLOGY

Downregulation in vivo of the invasion-suppressor molecule E-cadherin in experimental and clinical cancer

Marcus MareelKris VleminckxStefan VermeulenY GAOMarc BrackeFrans Van Roy

Bookchapter in Proceedings of the 24th International Symposium of the Princess Takamatsu Cancer Research Fund

Downregulation in vivo of the invasion-suppressor molecule E-cadherin in experimental and clinical cancer

Marcus MareelK VLEMINCKXStefan VermeulenGY ANMarc BrackeFrans Van Roy

INVASION PROMOTER VERSUS INVASION SUPPRESSOR MOLECULES - THE PARADIGM OF E-CADHERIN

Marcus MareelFrans Van RoyMarc Bracke

A1 Journal Article in MOLECULAR BIOLOGY REPORTS

Tamoxifen restores the E-cadherin function in human breast cancer MCF-7/6 cells and suppresses their invasive phenotype

Marc BrackeCorinne CharlierErik BruyneelCaroline LabitMarcus MareelVincent Castronovo

A1 Journal Article in CANCER RESEARCH

The invasion suppressor function of E-cadherin in mammary epithelioid cells

Marc BrackeStefan VermeulenErik BruyneelK VennekensGeorges De BruyneFrans Van RoyMarcus Mareel

1993

Differential regulation of gelatinase B and tissue-type plasminogen activator expression in human Bowes melanoma cells.

M HOUDEG DEBRUYNEMarc BrackeM INGELMANSUNDBERGG SKOGLUNDS MASUREJ VANDAMMEG OPDENAKKER

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

EXPRESSION OF E-CADHERIN IN EMBRYOGENETIC INGRESSION AND CANCER INVASION.

Marcus MareelMarc BrackeFrans Van RoyLuc Vakaet

A1 Journal Article in INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

HOST-REACTION AGAINST ALGINATE-POLYLYSINE MICROCAPSULES CONTAINING LIVING CELLS.

Geert VandenbosscheMarc BrackeCA CUVELIERHilde BortierMarcus MareelJean Paul Remon

A1 Journal Article in JOURNAL OF PHARMACY AND PHARMACOLOGY

HOST-REACTION AGAINST EMPTY ALGINATE-POLYLYSINE MICROCAPSULES - INFLUENCE OF PREPARATION PROCEDURE.

Geert VandenbosscheMarc BrackeCA CUVELIERHilde BortierMarcus MareelJean Paul Remon

A1 Journal Article in JOURNAL OF PHARMACY AND PHARMACOLOGY

HOW AND WHEN DO TUMOR-CELLS METASTASIZE.

Marcus MareelFrans Van RoyMarc Bracke

A1 Journal Article in CRITICAL REVIEWS IN ONCOGENESIS

Insulin-like growth factor I activates the invasion suppressor function of E-cadherin in MCF-7 human mammary carcinoma cells in vitro.

Marc BrackeBM VYNCKEErik BruyneelStefan VermeulenGK DEBRUYNENA VANLAREBEKEKris VleminckxFrans Van RoyMarcus Mareel

A1 Journal Article in BRITISH JOURNAL OF CANCER

MODULATION OF INVASIVE POTENTIAL IN DIFFERENT CLONAL SUBPOPULATIONS OF A RAT RHABDOMYOSARCOMA CELL-LINE (BA-HAN-1) BY DIFFERENTIATION INDUCTION.

CD GERHARZMarc BrackeMarcus MareelHE GABBERT

A1 Journal Article in CLINICAL & EXPERIMENTAL METASTASIS

Mechanisms of invasion: biological basis and clinical consequences

Marcus MareelMarc BrackeFrans Van Roy

A1 Journal Article in ANNALES DE BIOLOGIE CLINIQUE

Modulation of invasive potential in different clonal subpopulations of a rat rhabdomyosarcoma cell line (BA-HAN-1) by differentiation induction

CD GERHARZMarc BrackeMarcus MareelHE GABBERT

A2 Journal Article in Clin. Exp. Metastasis, 11

1992

E-Cadherin expression: a counterbalance for cancer cell invasion.

Marcus MareelKris VleminckxStefan VermeulenMarc BrackeFrans Van Roy

A1 Journal Article in BULLETIN DU CANCER

Homotypic cell-cell adhesion molecules and tumor invasion

Marcus MareelKris VleminckxStefan VermeulenY GaoLuc VakaetMarc BrackeFrans Van Roy

A1 Journal Article in PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY

Inhibition of invasion of MCF-7/6 human breast-carcinoma cells-invitro by Methanobacterium-thermoautotrophicum extract.

PC RAEMAKERS-FRANKENMarc BrackeN VANLAREBEKEB VYNCKEMarcus Mareel

A1 Journal Article in ANTICANCER RESEARCH

Interleukin-1 is a motility factor for human breast carcinoma cells in vitro : additive effect with interleukin-6

Bruno VerhasseltJozef Van DammeNicolas Van LarebekeW PutMarc BrackeC De PotterMarcus Mareel

A1 Journal Article in EUROPEAN JOURNAL OF CELL BIOLOGY

Invasive epithelial cells show more fast plasma membrane movements than related or parental non-invasive cells.

N VANLAREBEKEMarc BrackeMarcus Mareel

A1 Journal Article in CYTOMETRY

Modulation of invasion in vitro and in vivo

Marcus MareelK VLEMINCKXY GAONicolas Van LarebekeMarc BrackeFrans Van Roy

Simple method for quantification of fast plasma-membrane movements

Nicolas Van LarebekeMarc BrackeMarcus Mareel

A1 Journal Article in CYTOMETRY

The use of spheroids in the study of invasion

Marc BrackeHans RomijnLuc VakaetBarbara VynckeMarc De MetsMarcus Mareel

Bookchapter in Spheroid culture in cancer research

1991

ABSENCE OF LAMININ DEPOSITION IN BREAST-CANCER AND METASTASES EXCEPT TO THE BRAIN.

V CASTRONOVOMarc BrackeMarcus MareelM REZNIKJM FOIDART

A1 Journal Article in PATHOLOGY RESEARCH AND PRACTICE

Arrest of MCF-7 cell migration by laminin in vitro: possible mechanisms

P CoopmanBruno VerhasseltMarc BrackeGeorges De BruyneV CastronovoM SobelJM FoidartFrans Van RoyMarcus Mareel

A1 Journal Article in CLINICAL & EXPERIMENTAL METASTASIS

EFFECT OF CATECHINS AND CITRUS FLAVONOIDS ON INVASION INVITRO.

Marc BrackeB VYNCKEG OPDENAKKERJM FOIDARTG DEPESTELMarcus Mareel

A1 Journal Article in CLINICAL & EXPERIMENTAL METASTASIS

INFLUENCE OF BASEMENT-MEMBRANE MOLECULES ON DIRECTIONAL MIGRATION OF HUMAN BREAST CELL-LINES INVITRO.

PJ COOPMANMarc BrackeJC LISSITZKYGK DEBRUYNEFrans Van RoyJM FOIDARTMarcus Mareel

A1 Journal Article in JOURNAL OF CELL SCIENCE

Metastasemodellen.

Marcus MareelMarc BrackeP DE BAETSELIERFrans Van Roy

A3 Journal Article in TIJDSCHRIFT VOOR KANKER

Normal and chimeric avian embryo ecosystems of invasion

Marcus MareelMarc BrackeY GaoFrans Van Roy

A2 Journal Article in EUROPEAN ARCHIVES OF BIOLOGY

RETINOIC ACID MODULATES BOTH INVASION AND PLASMA-MEMBRANE RUFFLING OF MCF-7 HUMAN MAMMARY-CARCINOMA CELLS-INVITRO.

Marc BrackeNA VANLAREBEKEBM VYNCKEMarcus Mareel

A1 Journal Article in BRITISH JOURNAL OF CANCER

1990

Assays in vitro and in vivo for invasion and metastasis : application to drug testing

Marcus MareelMarc BrackeErik BruyneelNicolas Van LarebekeLieve BourgoisMarc De Mets

Effect of flavonoids on cancer cell invasiveness

Marc BrackeB VynckeG De PestelLuc VakaetL BourgoisNicolas Van LarebekeHilde BortierMarcus Mareel

HORMONE SENSITIVITY INVITRO AND INVIVO OF V-RAS-TRANSFECTED MCF-7 CELL DERIVATIVES.

Frans Van RoyMarcus MareelKris VleminckxRudi BeyaertWalther FiersN DEVLEESCHOUWERC MUQUARDTN LEGROSMarc BrackeG LECLERCQ

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

INVASION AND METASTASIS CONTROL - IMPLICATIONS FOR INCREASED THERAPEUTIC INDEX OF ANTITUMOR DRUGS.

Marcus MareelMarc BrackeErik BruyneelN VANLAREBEKEM DEMETS

A1 Journal Article in CANCER TREATMENT REVIEWS

THE PRESENCE OF PLASMIN RECEPTORS ON 3 MAMMARY-CARCINOMA MCF-7 SUBLINES.

P CORRECMC FONDANECHEMarc BrackeP BURTIN

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

1989

Acquisition of tumorigenic potential in the human myoepithelial HBL 100 cell line is associated with decreased expression of HLA class I, class II and integrin ß 3 and with increased expression of c-myc.

P KRIEFC SAINT-RUFMarc BrackeC BOUCHEIXC BILLARDM BILLARDR CASSINGENAC JASMINMarcus MareelB AZZARONE

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Strategies for the study of tumor invasion using an assay in vitro.

Marc BrackeB VYNCKEP COOPMANMarcus Mareel

A1 Journal Article in PATHOLOGIE BIOLOGIE

The flavonoid tangeretin inhibits invasion of MO4 mouse cells into embryonic chick heart in vitro.

Marc BrackeBM VYNCKENicolas Van LarebekeErik BruyneelGeorges De BruyneGH DE PESTELWJ DE COSTERMF ESPEELMarcus Mareel

A1 Journal Article in CLINICAL & EXPERIMENTAL METASTASIS

1988

Flavonoids inhibit malignant tumor invasion in vitro

Marc BrackeG De PestelV CastronovoB VynckeJM FoidartLuc VakaetMarcus Mareel

Interactions of invasive cells with native and modified extracellular matrix in vitro

Marc BrackeV CastronovoGeorges De BruyneP CoopmanJM FoidartMarcus Mareel

Invasiveness in vitro of mixed aggregates composed of two human mammary cell lines MCF-7 and HBL-100.

Georges De BruyneMarc BrackeL PLESSERSMarcus Mareel

A1 Journal Article in INVASION & METASTASIS

1987

Flavonoids : tools for the study of tumor invasion in vitro

Marc BrackeRM Van CauwenbergeMarcus MareelV CastronovoJM Foidart

Role of laminin and α-galactosyl cell surface residues in tumour invasion and metastasis

V CastronovoP MahieuMarc BrackeMarcus MareelC ColinR LambotteJM Foidart

The anti-invasive flavonoid (+)-catechin binds to laminin and abrogates the effect of laminin on cell morphology and adhesion.

Marc BrackeV CASTRONOVORM VAN CAUWENBERGELuc VakaetP STROJNYJM FOIDARTMarcus Mareel

A1 Journal Article in EXPERIMENTAL CELL RESEARCH

1986

Action mechanisms of anti-invasive agents.

Marc BrackeRM VAN CAUWENBERGEGA STORMEP COOPMANNicolas Van LarebekeMarcus Mareel

A1 Journal Article in ANTICANCER RESEARCH

Confrontation of an invasive (MO4) and a non-invasive (MDCK) cell line with embryonic chick heart fragments in serum-free culture media.

Marc BrackeMarc De MetsRM VAN CAUWENBERGELuc VakaetGeorges De BruyneMarcus Mareel

Expression of cell surface glycoproteins in tumour invasion in vitro

Marcus MareelC DragonettiR HoogheErik BruyneelMarc BrackeFrans Van RoyJ GaoGeorges De BruyneWalther Fiers

Protein degradation during different extraction procedures of malignant cells

J SegersM RabaeyGeorges De BruyneMarc BrackeMarcus Mareel

Tumour invasion and metastasis: major causes of therapeutic failure.

Marcus MareelMarc BrackeER BOGHAERT

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

1985

Mechanisms of tumor spread : a brief overview

Marcus MareelMarc BrackeGA Storme

1984

(+)-Catechin inhibits the invasion of malignant fibrosarcoma cells into chick heart in vitro.

Marc BrackeRM VAN CAUWENBERGEMarcus Mareel

A1 Journal Article in CLINICAL & EXPERIMENTAL METASTASIS

Anti-invasive effect of (+)-catechin in vitro.

Marc BrackeR VAN CAUWENBERGEMarcus Mareel

A3 Journal Article in Verhandlungen der Deutschen Gesellschaft für Pathologie

Interaction of malignant cells with salt-extracted cartilage in vitro

Marc BrackeRita M-L Van CauwenbergeMarcus Mareel

A1 Journal Article in CANCER RESEARCH

1983

Morfologische studie van de resistentie van kraakbeen tegen invasie