Research Explorer

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Researcher

Malaïka Van der Linden

Publications & Research Data

Awards & Distinctions

44 Results

2025

AI-driven histologic analysis of human Achilles tendinopathy provides a roadmap to unravel pathogenesis

Guillaume PlanckaertArne BurssensFlore StappersJulie CoudenysSofia DemolderIrem KayaMalaïka Van der LindenAmanda GonçalvesKelly LemeireBenjamin Pavie et al.

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

BonAIr: an AI-driven histological validation of human Achilles tendinopathy provides a roadmap to unravel pathogenesis

Guillaume PlanckaertArne BurssensFlore StappersIrem KayaMalaïka Van der LindenAmanda GonçalvesBenjamin PavieAmber VanhaeckeJo Van DorpeJan Victor et al.

Proteomics-based analysis of laser-capture micro-dissected, formalin-fixed paraffin-embedded tissue samples

Teresa MaiaDelphi Van HaverSara DufourMalaïka Van der LindenAmélie DendoovenFrancis ImpensSimon Devos

Bookchapter in Tissue Proteomics : Methods and Protocols

2024

Innovative label-free lymphoma diagnosis using infrared spectroscopy and machine learning on tissue sections

Charlotte DelrueMattias HofmansJo Van DorpeMalaïka Van der LindenZen Van GaeverTessa KerreMarijn SpeeckaertSander De Bruyne

A1 Journal Article in COMMUNICATIONS BIOLOGY

Osteopontin characterizes bile duct-associated macrophages and correlates with liver fibrosis severity in primary sclerosing cholangitis

Kevin De MuynckLander HeyerickFederico Francesco De PontiBart VanderborghtTim MeeseSanne Van CampenhoutLeen BaudonckEva GijbelsPedro M. RodriguesJesus M. Banales et al.

A1 Journal Article in HEPATOLOGY

Pilot study on the use of attenuated total reflectance-Fourier transform infrared spectroscopy for diagnosing and characterizing cardiac amyloidosis

Charlotte DelrueAnnelore VandendriesscheAmélie DendoovenMalaïka Van der LindenMarijn SpeeckaertSander De Bruyne

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma

Stien De ConinckRenate De SmedtBéatrice LintermansLindy ReunesHansen J. KosasihAlexandra ReekmansLauren M. BrownNadine Van RoyBruno PalhaisJuliette Roels et al.

A1 Journal Article in HAEMATOLOGICA

2023

Exploring the cell-free total RNA transcriptome in diffuse large B-cell lymphoma and primary mediastinal B-cell lymphoma patients as biomarker source in blood plasma liquid biopsies

Philippe DecruyenaereEdoardo GiuiliKimberly VerniersJasper AnckaertKatrien De GroveMalaïka Van der LindenDries DeerenJo Van DorpeFritz OffnerJo Vandesompele

A1 Journal Article in FRONTIERS IN ONCOLOGY

Systemic mastocytosis with myeloid sarcoma and B-CLL : molecular and clonal heterogeneity in a rare case of SM-AHN

Philippe DecruyenaereDominiek MazureIne MoorsJo Van DorpeMalaïka Van der LindenBarbara DenysMattias HofmansFritz Offner

Systemic mastocytosis with myeloid sarcoma and B-CLL : molecular and clonal heterogeneity in a rare case of SM-AHN with review of literature

Philippe DecruyenaereDominiek MazureIne MoorsJo Van DorpeMalaïka Van der LindenBarbara DenysMattias HofmansFritz Offner

A1 Journal Article in ACTA CLINICA BELGICA

2022

Application of an ultrasensitive NGS-based blood test for the diagnosis of early-stage lung cancer : sensitivity, a hurdle still difficult to overcome

Malaïka Van der LindenBram Van GaeverLennart RamanKarim VermaelenIngel DemedtsVeerle SurmontUlrike HimpeYolande LievensLiesbeth FerdinandeFranceska Dedeurwaerdere et al.

A1 Journal Article in CANCERS

Liquid biopsies for integrated cancer (differential) diagnosis : from whole-genome to targeted and from genomics to epigenomics

Malaïka Van der LindenJo Van DorpeBjörn MentenKathleen Claes

Shallow whole-genome sequencing : a useful, easy to apply molecular technique for CNA detection on FFPE tumor tissue : a glioma-driven study

Kim Van der EeckenMalaïka Van der LindenLennart RamanDavid CreytensFranceska DedeurwaerdereKoen De WinneLiesbeth FerdinandeMartin LammensBjörn MentenIsabelle Rottiers et al.

A1 Journal Article in VIRCHOWS ARCHIV

Shallow-depth sequencing of cell-free DNA for Hodgkin and diffuse large B-cell lymphoma (differential) diagnosis : a standardized approach with underappreciated potential

Lennart RamanMalaïka Van der LindenCiel De VriendtBliede Van den BroeckKristoff MuylleDries DeerenFranceska DedeurwaerdereSofie VerbekeAmélie DendoovenKatrien De Grove et al.

A1 Journal Article in HAEMATOLOGICA

Shallow-depth sequencing of cell-free DNA for Hodgkin and diffuse large B-cell lymphoma (differential) diagnosis: a standardized approach with underappreciated potential

Lennart RamanMalaïka Van Der LindenCiel De VriendtBliede Van den BroeckKristoff MuylleDries DeerenFranceska DedeurwaerdereSofie VerbekeAmélie DendoovenKatrien De Grove et al.

U Journal Article in Haematologica

The feasibility of using liquid biopsies as a complementary assay for copy number aberration profiling in routinely collected paediatric cancer patient samples

Ruben Van PaemelCharlotte VandeputteLennart RamanJolien Van ThorreLeen WillemsJo Van DorpeMalaïka Van der LindenJilke De WildeAndries De KokerBjörn Menten et al.

A1 Journal Article in EUROPEAN JOURNAL OF CANCER

2021

Myxoid hepatocellular adenoma, a rare variant of hepatocellular adenoma with distinct imaging features : a case report with immunohistochemical and molecular analysis and literature review

Nicolas De VosJoni Van der MeulenMalaïka Van der LindenKathleen ClaesAnn-Sophie CandaeleAude VanlanderRoberto TroisiHans Van VlierberghePeter SmeetsJo Van Dorpe et al.

A1 Journal Article in CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY

Myxoid pleomorphic liposarcoma : a clinicopathologic, immunohistochemical, molecular genetic and epigenetic study of 12 cases, suggesting a possible relationship with conventional pleomorphic liposarcoma

David CreytensAndrew L. FolpeChristian KoelscheThomas MentzelLiesbeth FerdinandeJoost M. van GorpMalaïka Van der LindenLennart RamanBjörn MentenKaren Fritchie et al.

A1 Journal Article in MODERN PATHOLOGY

Primary sellar melanocytoma

Mathieu ClausMalaïka Van der LindenJo Van DorpeBruno LapauwGuy T'Sjoen

A1 Journal Article in PITUITARY

2020

Detection of copy number alterations by shallow whole-genome sequencing of formalin-fixed, paraffin-embedded tumor tissue

Malaïka Van der LindenLennart RamanAnsel Vander TrappenAnnelies DheedeneMatthias De SmetTom SanteDavid CreytensYolande LievensBjörn MentenJo Van Dorpe et al.

A1 Journal Article in ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Shallow whole-genome sequencing of cell-free DNA for B-cell lymphoma diagnosis and disease monitoring : a standardized approach with underappreciated potential

Malaïka Van der LindenLennart RamanCiel De VriendtBliede Van den BroeckKristoff MuylleDries DeerenKathleen ClaesBjörn MentenFritz OffnerJo Van Dorpe

Shallow whole-genome sequencing of cell-free DNA for B-cell lymphoma diagnosis and disease monitoring: a standardized approach with underappreciated potential

Malaïka Van der LindenLennart RamanCiel De VriendtBliede Van den BroeckKristoff MuylleDries DeerenKathleen ClaesBjörn MentenFritz OffnerJo Van Dorpe

Shallow whole-genome sequencing of plasma cell-free DNA accurately differentiates small from non-small cell lung carcinoma

Lennart RamanMalaïka Van der LindenKim Van der EeckenKarim VermaelenIngel DemedtsVeerle SurmontUlrike HimpeFranceska DedeurwaerdereLiesbeth FerdinandeYolande Lievens et al.

A1 Journal Article in GENOME MEDICINE

2019

A fast, affordable and minimally-invasive diagnostic test for Cancer of Unknown Primary (CUP) using DNA methylation profiling

Jilke De WildeRuben Van PaemelCharlotte VandeputteAndries De KokerJoni Van der MeulenMalaïka Van der LindenNico CallewaertJo Van DorpeDavid CreytensBram De Wilde et al.

Circulating cell-free DNA for response evaluation of intravascular lymphoma

Dries DeerenMalaïka Van der LindenFranceska DedeurwaerdereLien DeleuCaressa MeertBjörn MentenJo Van Dorpe

A1 Journal Article in ANNALS OF HEMATOLOGY

Detection of genome-wide copy number alterations in tumor tissue and cell-free DNA of pancreatic cancer patients

Greet WiemeFrederik BerrevoetAude VanlanderJo Van DorpeAnne HoorensMalaïka Van der LindenBram PartonJurgen van LimmenANN DE BRUYNEMarc De Man et al.

Detection of genome-wide copy number alterations in tumor tissue and cell-free DNA of pancreatic cancer patients

Greet WiemeFrederik BerrevoetAude VanlanderJo Van DorpeAnne HoorensMalaïka Van der LindenBram PartonJurgen van LimmenANN DE BRUYNEMarc De Man et al.

Detection of genome-wide copy number alterations in tumor tissue and cell-free DNA of pancreatic cancer patients

Greet WiemeFrederik BerrevoetAude VanlanderJo Van DorpeAnne HoorensMalaïka Van der LindenBram PartonJurgen van LimmenANN DE BRUYNEMarc De Man et al.

Detection of genome-wide copy number alterations in tumor tissue and cell-free DNA of pancreatic cancer patients

Greet WiemeFrederik BerrevoetAude VanlanderJo Van DorpeAnne HoorensMalaïka Van der LindenBram PartonJurgen van LimmenANN DE BRUYNEMarc De Man et al.

Detection of genome-wide copy number alterations in tumor tissue and cell-free DNA of pancreatic cancer patients

Greet WiemeFrederik BerrevoetAude VanlanderJo Van DorpeAnne HoorensMalaïka Van der LindenBram PartonJurgen van LimmenANN DE BRUYNEMarc De Man et al.

Exploring the potential of shallow whole-genome sequencing for diagnosis and disease monitoring of lymphoma in liquid biopsy

Lennart RamanMalaïka Van der LindenCiel De VriendtBliede Van den BroeckKristoff MuylleDries DeerenBjörn MentenFritz OffnerJo Van Dorpe

Faster, cheaper and more accurate diagnosis of cancer of unknown primary (CUP) by using methylation profiling.

Jilke De WildeRuben Van PaemelCharlotte VandeputteAndries De KokerJoni Van der MeulenMalaïka Van der LindenNico CallewaertJo Van DorpeDavid CreytensBram De Wilde et al.

Shallow whole genome sequencing on circulating cell-free DNA in pediatric cancer patients

Charlotte VandeputteJolien Van ThorreRuben Van PaemelAndries De KokerLeen WillemsJo Van DorpeMalaïka Van der LindenJilke De WildeBjörn MentenL. van Zogchel et al.

Shallow whole genome sequencing on circulating cell-free DNA in pediatric cancer patients

Charlotte VandeputteJolien Van ThorreRuben Van PaemelAndries De KokerLeen WillemsJo Van DorpeMalaïka Van der LindenJilke De WildeBjörn MentenLieke van Zogchel et al.

Shallow whole genome sequencing on circulating cell-free DNA in pediatric cancer patients

Charlotte VandeputteJolien Van ThorreRuben Van PaemelAndries De KokerLeen WillemsJo Van DorpeMalaïka Van der LindenJilke De WildeBjörn MentenLieke van Zogchel et al.

Successful copy number alteration profiling using circulating cell-free tumor DNA as a non-invasive alternative for tissue biopsies in pediatric cancer patients

Charlotte VandeputteJolien Van ThorreRuben Van PaemelAndries De KokerLeen WillemsJo Van DorpeMalaïka Van der LindenJilke De WildeBjörn MentenLieke van Zogchel et al.

2018

Biallelic and monoallelic ESR2 variants associated with 46,XY disorders of sex development

Dorien BaetensTülay GüranBerenice B MendoncaNathalia L GomesLode De CauwerFrank PeelmanHannah VerdinMarnik VuylstekeMalaïka Van der LindenHans Stoop et al.

A1 Journal Article in GENETICS IN MEDICINE

Detection of copy number alterations using shallow whole genome sequencing on formalin-fixed paraffin-embedded tumor tissue

Malaïka Van der LindenLennart RamanAnsel Vander TrappenAnnelies DheedeneMatthias De SmetTom SanteDavid CreytensBjörn MentenJo Van DorpeNadine Van Roy

Detection of copy number alterations using shallow whole genome sequencing on formalin-fixed paraffin-embedded tumor tissue

Malaïka Van der LindenLennart RamanAnsel Vander TrappenAnnelies DheedeneMatthias De SmetTom SanteDavid CreytensBjörn MentenJo Van DorpeNadine Van Roy

Shallow whole genome sequencing allows successful copy number profiling in formalin-fixed paraffin-embedded material in neuroblastoma patients

Charlotte VandeputteRuben Van PaemelBram De WildeMalaïka Van der LindenJo Van DorpeBjörn MentenFranki SpelemanNadine Van RoyKatleen De Preter

2017

Pancreatic cancer : hope to improve prognosis through thorough analysis of DNA and RNA biomarkers for detection and therapy monitoring in liquid biopsies

Greet WiemeFrederik BerrevoetAude VanlanderMarc De ManKaren GeboesJo Van DorpeAnne HoorensMalaïka Van der LindenJurgen van LimmenANN DE BRUYNE et al.

Shallow whole genome sequencing on circulating cell-free DNA allows reliable non-invasive copy number profiling in neuroblastoma patients

Nadine Van RoyMalaïka Van der LindenPauline DepuydtBjörn MentenAnnelies DheedeneCharlotte VandeputteJo Van DorpeGenevieve LaureysMarjolijn RenardTom Sante et al.

Shallow whole genome sequencing on circulating cell-free DNA allows reliable noninvasive copy-number profiling in neuroblastoma patients

Nadine Van RoyMalaïka Van der LindenBjörn MentenAnnelies DheedeneCharlotte VandeputteJo Van DorpeGenevieve LaureysMarleen RenardTom SanteTim Lammens et al.

A1 Journal Article in CLINICAL CANCER RESEARCH

2016

Development of a blood test for selection of lung cancer patients who could benefit from immunotherapy.

Malaïka Van der LindenKarim VermaelenIngel DemedtsVeerle SurmontKathleen ClaesBjörn MentenJo Van Dorpe