Research Explorer

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Researcher

Lynn Verstrepen

Awards & Distinctions

21 Results

2018

Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice

Elodie KipJens StaalHG TimaLynn VerstrepenM RomanoKelly LemeireV SuinA HamoudaM BaensClaude Libert et al.

A1 Journal Article in JOURNAL OF VIROLOGY

MALT1 controls attenuated rabies virus by inducing early inflammation and T cell activation in the brain

Elodie KipJens StaalLynn VerstrepenHG TimaS TerrynM RomanoKelly LemeireV SuinA HamoudaM Kalai et al.

A1 Journal Article in JOURNAL OF VIROLOGY

Mepazine inhibits RANK-induced osteoclastogenesis independent of its MALT1 inhibitory function

Laura MeloniLynn VerstrepenMarja KreikeJens StaalYasmine DriegeInna AfoninaRudi Beyaert

A1 Journal Article in MOLECULES

2017

Unusual lipid A from a cold-adapted bacterium : detailed structural characterization

Angela CasilloMarcello ZiacoBuko LindnerErmenegilda ParrilliDominik SchwudkeAurora Holgado MuñozLynn VerstrepenFilomena SanninoRudi BeyaertRosa Lanzetta et al.

A1 Journal Article in CHEMBIOCHEM

2016

TRAF2 multitasking in TNF receptor-induced signaling to NF-κB, MAP kinases and cell death

Alice BorghiLynn VerstrepenRudi Beyaert

A1 Journal Article in BIOCHEMICAL PHARMACOLOGY

2014

Receptor proximal kinases in NF-κB signaling as potential therapeutic targets in cancer and inflammation

Lynn VerstrepenRudi Beyaert

A1 Journal Article in BIOCHEMICAL PHARMACOLOGY

The biology of A20-binding inhibitors of NF-κB activation (ABINs)

Lynn VerstrepenIsabelle CarpentierRudi Beyaert

A1 Journal Article in Advances in Experimental Medicine and Biology

2013

IκB kinase ε (IKKε): a therapeutic target in inflammation and cancer

Kelly VerhelstLynn VerstrepenIsabelle CarpentierRudi Beyaert

A1 Journal Article in BIOCHEMICAL PHARMACOLOGY

2012

A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7

Kelly VerhelstIsabelle CarpentierMarja KreikeLaura MeloniLynn VerstrepenTobias KenscheIvan DikicRudi Beyaert

A1 Journal Article in EMBO JOURNAL

No ubiquitin anchors and fully RIGged

Lynn VerstrepenRudi Beyaert

Editorial material

2011

Linear ubiquitination in NF-κB signaling and inflammation: what we do understand and what we do not

Kelly VerhelstLynn VerstrepenIsabelle CarpentierRudi Beyaert

A1 Journal Article in BIOCHEMICAL PHARMACOLOGY

TAX1BP1, a ubiquitin-binding adaptor protein in innate immunity and beyond

Lynn VerstrepenKelly VerhelstIsabelle CarpentierRudi Beyaert

A1 Journal Article in TRENDS IN BIOCHEMICAL SCIENCES

2010

Expression, biological activities and mechanisms of action of A20 (TNFAIP3)

Lynn VerstrepenKelly VerhelstGeert van LooIsabelle CarpentierSteven C LeyRudi Beyaert

A1 Journal Article in BIOCHEMICAL PHARMACOLOGY

2009

ABINs: A20 binding inhibitors of NF-kappa B and apoptosis signaling

Lynn VerstrepenIsabelle CarpentierKelly VerhelstRudi Beyaert

A1 Journal Article in BIOCHEMICAL PHARMACOLOGY

Cellular expression of A20 and ABIN-3 in response to Toll-like receptor-4 stimulation

Kelly VerhelstLynn VerstrepenBeatrice CoornaertIsabelle CarpentierRudi Beyaert

Bookchapter in Toll-like receptors : methods and protocols

2008

ABINs inhibit EGF receptor-mediated NF-kappa B activation and growth of EGF receptor-overexpressing tumour cells

Lieven HuangLynn VerstrepenKaren HeyninckAndy WullaertH REVETSP DE BAETSELIERRudi Beyaert

A1 Journal Article in ONCOGENE

Expression of the NF-kappa B inhibitor ABIN-3 in response to TNF and toll-like receptor 4 stimulation is itself regulated by NF-kappa B

Lynn VerstrepenM ADIB-CONQUYMarja KreikeIsabelle CarpentierC ADRIEJM CAVAILLONRudi Beyaert

A1 Journal Article in JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappa B activation

H IHAJM PELOPONESELynn VerstrepenG ZAPARTF IKEDACD SMITHMF STAROSTV YEDAVALLIKaren HeyninckI DIKIC et al.

A1 Journal Article in EMBO JOURNAL

TLR-4, IL-1R and TNF-R signaling to NF-kappa B: variations on a common theme

Lynn VerstrepenTine BekaertTL CHAUJan TavernierA CHARIOTRudi Beyaert

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

2007

Functional characterization of ABIN-3 and TAX1BP1 as negative regulators of NF-kappaB signaling

Lynn VerstrepenRudi Beyaert

LIND/ABIN-3 is a novel lipopolysaccharide-inducible inhibitor of NF-kappa B activation

Andy WullaertLynn VerstrepenSofie Van HuffelM Adib-ConquySigrid CornelisMarja KreikeMira HaegmanKarim El BakkouriMatthew SandersKelly Verhelst et al.

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY