Research Explorer

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Researcher

Lynn Elton

Awards & Distinctions

6 Results

2016

MALT1 cleaves the E3 ubiquitin ligase HOIL-1 in activated T cells, generating a dominant negative inhibitor of LUBAC-induced NF-κB signaling

Lynn EltonIsabelle CarpentierJens StaalYasmine DriegeMira HaegmanRudi Beyaert

A1 Journal Article in FEBS JOURNAL

2015

MALT1-a universal soldier: multiple strategies to ensure NF-κB activation and target gene expression

Inna AfoninaLynn EltonIsabelle CarpentierRudi Beyaert

A1 Journal Article in FEBS JOURNAL

The multifaceted role of the E3 ubiquitin ligase HOIL-1: beyond linear ubiquitination

Lynn EltonIsabelle CarpentierKelly VerhelstJens StaalRudi Beyaert

A1 Journal Article in IMMUNOLOGICAL REVIEWS

2014

Identification and functional characterization of novel MALT1 substrates

Lynn EltonRudi BeyaertJens Staal

Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis

Conor Mc GuireLynn EltonPeter WieghoferJens StaalSofie VoetAnnelies DemeyerDaniel NagelDaniel KrappmannMarco PrinzRudi Beyaert et al.

A1 Journal Article in JOURNAL OF NEUROINFLAMMATION

2013

Paracaspase MALT1 deficiency protects mice from autoimmune-mediated demyelination

Conor Mc GuirePeter WieghoferLynn EltonDavid MuylaertMarco PrinzRudi BeyaertGeert van Loo

A1 Journal Article in JOURNAL OF IMMUNOLOGY