Research Explorer

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Researcher

Lukas Nollet

15 Results

2023

Inorganic pyrophosphate plasma levels are decreased in pseudoxanthoma elasticum patients and heterozygous carriers but do not correlate with the genotype or phenotype

Matthias Van GilsJustin DepauwPaul CouckeShari AertsShana VerschuereLukas NolletOlivier Vanakker

A1 Journal Article in JOURNAL OF CLINICAL MEDICINE

2022

Attenuation of dysfunctional DNA damage response and PARP1 signaling by minocycline reduces ectopic calcification in pseudoxanthoma elasticum

Lukas NolletMatthias Van GilsAndy WillaertPaul CouckeOlivier Vanakker

Clinical and subclinical findings in heterozygous ABCC6 carriers : results from a Belgian cohort and clinical practice guidelines

Lukas NolletLaurence CampensJulie De ZaeytijdBart LeroyDimitri HemelsoetPaul CouckeOlivier Vanakker

A1 Journal Article in JOURNAL OF MEDICAL GENETICS

Minocycline attenuates excessive DNA damage response and reduces ectopic calcification in pseudoxanthoma elasticum

Lukas NolletMatthias Van GilsAndy WillaertPaul CouckeOlivier Vanakker

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

Minocycline counteracts ectopic calcification in a murine model of pseudoxanthoma elasticum : a proof-of-concept study

Elise BouderliqueLukas NolletEmmanuel LetavernierOlivier Vanakker

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial dysfunction and oxidative stress in hereditary ectopic calcification diseases

Lukas NolletOlivier Vanakker

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Plasma inorganic pyrophosphate levels correlate to specific phenotypes and variant archetypes of ABCC6 in pseudoxanthoma elasticum patients

Matthias Van GilsJustin DepauwShana VerschuereLukas NolletOlivier Vanakker

Serum calcification propensity T50 associates with disease severity in patients with pseudoxanthoma elasticum

Lukas NolletMatthias Van GilsSuzanne FischerLaurence CampensSwapna KarthikAndreas PaschJulie De ZaeytijdBart LeroyDaniel DevosTine De Backer et al.

A1 Journal Article in JOURNAL OF CLINICAL MEDICINE

2021

Inorganic pyrophosphate plasma levels are decreased in pseudoxanthoma elasticum (PXE) patients and carriers, and correlate with the severity of the vascular phenotype

Matthias Van GilsJustin DepauwPaul CouckeShana VerschuereLukas NolletOlivier Vanakker

Pseudoxanthoma elasticum (PXE) patients and heterozygous carriers have decreased plasma PPi levels which correlate with the cardio(vascular) phenotype

Matthias Van GilsJustin DepauwShana VerschuereLukas NolletOlivier Vanakker

2020

From membrane to mineralization : the curious case of the ABCC6 transporter

Shana VerschuereMatthias Van GilsLukas NolletOlivier Vanakker

A1 Journal Article in FEBS LETTERS

Primaire ectopische mineralisatieaandoeningen : van (vaat)verkalking tot syndroom

Andreas DecockEva De VilderLukas NolletOlivier Vanakker

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Pseudoxanthoma elasticum (PXE) patients and heterozygous carriers have decreased plasma PPi levels which correlate with the (cardio)vascular phenotype.

Matthias Van GilsJustin DepauwShana VerschuereLukas NolletOlivier Vanakker

2019

Cellular signaling in pseudoxanthoma elasticum : an update

Matthias Van GilsLukas NolletEwout VerlyNancy DeianovaOlivier Vanakker

A1 Journal Article in CELLULAR SIGNALLING

The role of vitamin K and its related compounds in Mendelian and acquired ectopic mineralization disorders

Lukas NolletMatthias Van GilsShana VerschuereOlivier Vanakker

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES