Research Explorer

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Researcher

Louis Onghena

Awards & Distinctions

21 Results

2025

Mitochondrial dysfunction characterises the multigenerational effects of maternal obesity on MASLD

Anneleen HeldensMilton Boaheng AntwiLouis OnghenaTim MeeseYannick GansemansJoél SmetEllen DupontXavier VerhelstSarah RaevensHans Van Vlierberghe et al.

A1 Journal Article in JHEP REPORTS

PPARα-ERRα crosstalk mitigates metabolic dysfunction-associated steatotic liver disease progression

Milton Boaheng AntwiSander LefereDorien ClarisseLisa KoorneefAnneleen HeldensLouis OnghenaKylian DecroixDaria FijalkowskaJonathan ThommisMadeleine Hellemans et al.

A1 Journal Article in METABOLISM-CLINICAL AND EXPERIMENTAL

The double-edged sword of metabolic and bariatric surgery : extending the biliary limb can trigger bacterial translocation, sepsis, and liver inflammation : an experimental study

Louis OnghenaAnneleen HeldensKim De PaepeMilton Boaheng AntwiHans Van VlierbergheSarah RaevensXavier VerhelstAnne HoorensLindsey DevisscherYves Van Nieuwenhove et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF SURGERY

The pan-PPAR agonist lanifibranor reduces portal pressure independent of fibrosis reduction through the splanchnic vasculature

Anneleen HeldensChristophe CasteleynLouis OnghenaMilton Boaheng AntwiSara NeytBenedicte DescampsChristian VanhoveXavier VerhelstSarah RaevensHans Van Vlierberghe et al.

A1 Journal Article in BIOMEDICINE & PHARMACOTHERAPY

2024

Bariatric surgery is a major independent factor of disease progression in cirrhotic patients with alcohol-related liver disease

Louis OnghenaLindsey DevisscherHans Van VlierbergheSarah RaevensXavier VerhelstYves Van NieuwenhoveSander LefereAnja Geerts

Bariatric surgery post-liver transplantation : a Belgian nationwide study

Louis OnghenaAnja GeertsFrederik BerrevoetJacques PirenneJef VerbeekEliano Bonaccorsi-RianiGeraldine DahlqvistLuisa VonghiaOlivier DetryJean Delwaide et al.

A1 Journal Article in LIVER TRANSPLANTATION

Evolution of health-related quality of life in liver transplantation patients in relation to acceptance and metabolic liver disease

Janne SuykensLouis OnghenaFrederik BerrevoetHans Van VlierbergheXavier VerhelstSarah RaevensEric HosteSander LefereAnja GeertsProf dr Carine Poppe

Prior metabolic and bariatric surgery is an independent determinant of severity of decompensation in alcohol-associated liver disease

Louis OnghenaYves Van NieuwenhoveHans Van VlierbergheLindsey DevisscherSarah RaevensXavier VerhelstSander LefereAnja Geerts

A1 Journal Article in UNITED EUROPEAN GASTROENTEROLOGY JOURNAL

The double-edged sword of bariatric surgery : extending the excluded limb can trigger bacterial translocation, liver inflammation and death

Louis OnghenaAnneleen HeldensMilton Boaheng AntwiLindsey DevisscherHans Van VlierbergheSarah RaevensXavier VerhelstAnne HoorensYves Van NieuwenhoveAnja Geerts et al.

Transgenerational maternal obesity induces mitochondrial dysfunction and aggravates MASLD, which can be reversed by metabolic drug candidates

Anneleen HeldensMilton Boaheng AntwiLouis OnghenaLindsey DevisscherXavier VerhelstSarah RaevensHans Van VlierbergheRuth De BruyneAnja GeertsSander Lefere

2023

Novel bariatric surgery models in mice-differential effects on body weight loss and fatty liver disease

Louis OnghenaAnneleen HeldensMilton Boaheng AntwiHans Van VlierbergheXavier VerhelstLindsey DevisscherYves Van NieuwenhoveAnja GeertsSander Lefere

Patients hospitalized with alcohol-related liver disease and prior bariatric surgery are more prone to develop acute-on-chronic liver failure

Louis OnghenaYves Van NieuwenhoveLaurissa DemeulenaereLindsey DevisscherXavier VerhelstHelena DegrooteSarah RaevensHans Van VlierbergheSander LefereAnja Geerts

A1 Journal Article in LIVER INTERNATIONAL

The pan-PPAR agonist lanifibranor decreases portal pressure in models of both hepatic and prehepatic portal hypertension

Anneleen HeldensChristophe CasteleynLouis OnghenaMilton Boaheng AntwiBenedicte DescampsChristian VanhoveXavier VerhelstHans Van VlierbergheLindsey DevisscherJean-Louis Junien et al.

2022

Illness cognitions and health-related quality of life in liver transplant patients related to length of stay, comorbidities and complications

Louis OnghenaFrederik BerrevoetAude VanlanderHans Van VlierbergheXavier VerhelstEric HosteCarine Poppe

A1 Journal Article in QUALITY OF LIFE RESEARCH

2021

Bariatric surgery and the liver : mechanisms, benefits, and risks

Sander LefereLouis OnghenaAude VanlanderYves Van NieuwenhoveLindsey DevisscherAnja Geerts

A1 Journal Article in OBESITY REVIEWS

2017

Extended right liver graft and the fate of segment IV : no split decisions

Louis OnghenaAude VanlanderFrederik BerrevoetRoberto Troisi

2016

Health-related quality of life improves further after liver transplantation and is influenced by length of stay

Louis OnghenaWouter DeveltereXavier RogiersRoberto TroisiFrederik BerrevoetAude VanlanderAnja GeertsHans Van VlierbergheXavier VerhelstProf dr Carine Poppe

Health-related quality of life is improved after liver transplantation and is related to disease acceptance, helplessness and perceived disease benefits

Louis OnghenaWouter DeveltereXavier RogiersRoberto TroisiFrederik BerrevoetAude VanlanderAnja GeertsHans Van VlierbergheProf dr Carine PoppeXavier Verhelst

Quality of life after liver transplantation : state of the art

Louis OnghenaWouter DeveltereProf dr Carine PoppeAnja GeertsRoberto TroisiAude VanlanderFrederik BerrevoetXavier RogiersHans Van VlierbergheXavier Verhelst

A2 Journal Article in WORLD JOURNAL OF HEPATOLOGY

2015

Health-related quality of life is improved after liver transplantation and is related to disease acceptance, helplessness and perceived disease benefits

Wouter DeveltereLouis OnghenaXavier RogiersRoberto TroisiFrederik BerrevoetAude VanlanderAnja GeertsHans Van VlierbergheXavier VerhelstProf dr Carine Poppe

Health-related quality of life is improved after liver transplantation and is related to disease acceptance, helplessness and perceived disease benefits

Louis OnghenaWouter DeveltereXavier RogiersRoberto TroisiFrederik BerrevoetAude VanlanderAnja GeertsHans Van VlierbergheXavier VerhelstProf dr Carine Poppe