Research Explorer

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Researcher

Lore Lapeire

Publications & Research Data

Awards & Distinctions

75 Results

2025

A living sarcoma biobank for translational research purposes

Stefanie GijselsMerlijn VekemanSuzanne FischerDavid CreytensAlexander AckermanAnaïs OngenaetLaurens BoiEline SegersJens De TemmermanFrancesca Casteur et al.

Complete remission with olaparib in BRIP1-mutated metastatic high-grade pleomorphic sarcoma : case study and literature review : an example of a genomic profiling-based tumor treatment, in a cancer type with high unmet clinical need

Alexander ThooftSofie JorisCeline JacobsDavid CreytensSylvie RotteyBrigitte MaesPhilippe AftimosLore Lapeire

A1 Journal Article in ACTA ONCOLOGICA

Correction : Kalisvaart et al. Relative wash-in rate in dynamic contrast-enhanced magnetic resonance imaging as a new prognostic biomarker for event-free survival in 82 patients with osteosarcoma : a multicenter study

Gijsbert M. KalisvaartRichard E. EvenhuisWillem GrootjansThomas Van Den BergheMartijn CallensJudith V. M. G. BovéeDavid CreytensHans GelderblomFrank M. SpeetjensLore Lapeire et al.

Developing and implementing a nurse-delivered and a web-based dyadic psychoeducational program for people with advanced cancer and their family caregivers : sharing experiences from a three-arm international randomized controlled trial (DIAdIC)

Aline De VleminckVincent Van GoethemSigrid DierickxOrphé MatthysKim BeernaertMogens GronvoldPhilip LarkinMonica GubertiErica WitkampJoanne Reid et al.

A2 Journal Article in PALLIATIVE CARE & SOCIAL PRACTICE

Evaluation of response to neoadjuvant chemotherapy in osteosarcoma using dynamic contrast-enhanced MRI : development and external validation of a predictive model

Thomas Van Den BergheGijsbert M. KalisvaartWillem GrootjansMaryse LejolyWouter HuysseJudith V.M.G. BovéeDavid CreytensHans GelderblomFrank M. SpeetjensLore Lapeire et al.

From biopsy to the bench and back : exploration of patient-derived tumour models and EV proteomic profiles to support therapeutic decision making for sarcoma patients

Suzanne FischerGwen SysAn HendrixLore Lapeire

Impact of a nurse-led and a web-based psychoeducational program for advanced cancer patients and their caregivers : results of a three-arm randomized controlled trial

Aline De VleminckOrphé MatthysElena TurolaSigrid DierickxLaure DombrechtVincent Van GoethemLuc DeliensLore LapeirePeter HudsonKim Eecloo et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF NURSING STUDIES

Influence of digital competence on participation and retention of patients with advanced cancer and their family caregivers in a randomized controlled trial with an e-Health component : findings from the DIAdIC trial

Vincent Van GoethemSigrid DierickxOrphé MatthysLuc DeliensLore LapeireVeerle SurmontKaren GeboesVincent RenardMogens GrønvoldPaul D’Alton et al.

A1 Journal Article in TELEMEDICINE AND E-HEALTH

Monitoring denosumab therapy of giant cell tumours of bone using a radiological-pathological correlation

Thomas Van Den BergheMaryse LejolyWouter HuysseDavid CreytensLore LapeireGwen SysKoenraad Verstraete

Preserving potential : surgeons as key partners in establishing a living sarcoma biobank for translational research purposes

Stefanie GijselsMerlijn VekemanSuzanne FischerDavid CreytensAlexander AckermanAnaïs OngenaetLaurens BoiEline SegersJens De TemmermanFrancesca Casteur et al.

A1 Journal Article in SURGICAL ONCOLOGY-OXFORD

Relative wash-in rate on dynamic contrast-enhanced MRI as a new prognostic factor in patients with osteosarcoma after neoadjuvant chemotherapy?

Thomas Van Den BergheGijsbert M. KalisvaartRichard E. EvenhuisWillem GrootjansJudith V.M.G. BovéeDavid CreytensHans GelderblomFrank M. SpeetjensLore LapeireGwen Sys et al.

2024

Case series of kaposi sarcoma in HIV-negative men who have sex with men : potential therapeutic approaches

Niels HilhorstBarbara DevochtEvelien VerhaegheLore LapeireLinos VandekerckhoveSoetkin DesmetMarie-Angélique De ScheerderLieve Brochez

A2 Journal Article in JOURNAL OF DERMATOLOGY RESEARCH AND THERAPY

Diagnosis and monitoring denosumab therapy of giant cell tumors of bone : radiologic-pathologic correlation

Maryse LejolyThomas Van Den BergheDavid CreytensWouter HuysseLore LapeireGwen SysKoenraad Verstraete

A1 Journal Article in SKELETAL RADIOLOGY

Diagnosis and monitoring denosumab therapy of giant cell tumours of bone : radiological-pathological correlation

Thomas Van Den BergheMaryse LejolyWouter HuysseDavid CreytensLore LapeireGwen SysKoenraad Verstraete

Diagnosis and monitoring denosumab therapy of giant cell tumours of bone : radiological-pathological correlation

Thomas Van Den BergheMaryse LejolyWouter HuysseDavid CreytensLore LapeireGwen SysKoenraad Verstraete

eHealth support for people with serious illness and their family caregivers

Vincent Van GoethemLuc DeliensJoachim CohenLore LapeireAline De Vleminck

Evaluation of response to neoadjuvant chemotherapy in osteosarcoma using dynamic contrast-enhanced MRI : development and external validation of a model

Gijsbert M. KalisvaartThomas Van Den BergheWillem GrootjansMaryse LejolyWouter HuysseJudith V. M. G. BovéeDavid CreytensHans GelderblomFrank M. SpeetjensLore Lapeire et al.

A1 Journal Article in SKELETAL RADIOLOGY

Generation of post-surgical minimal residual disease models to investigate metastasis in soft tissue sarcoma patient-derived orthotopic xenografts

Suzanne FischerDavid CreytensStefanie GijselsBenedicte DescampsLore LapeireAn HendrixGwen SysOlivier De Wever

A2 Journal Article in STAR PROTOCOLS

Policy brief of the Belgian Europe’s Beating Cancer Plan mirror group : children, adolescents and young adults with cancer

Hélène A. PoirelGabrielle SchittecatteFabienne Van AelstAd VandermeulenAlice GerbauxChristiani Andrade AmorimAn Van DammeAnne UyttebroeckBenedicte BrichardBram De Wilde et al.

A1 Journal Article in ARCHIVES OF PUBLIC HEALTH

RAF1-rearranged spindle cell mesenchymal tumor with calcification and heterotopic ossification : a case report and review of literature

Fleur CordierSiebe LoontiensJoni Van der MeulenLore LapeireGabriëlle van RamshorstGwen SysJo Van DorpeDavid Creytens

A1 Journal Article in INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY

Relative wash-in rate in dynamic contrast-enhanced magnetic resonance imaging as a new prognostic biomarker for event-free survival in 82 patients with osteosarcoma : a multicenter study

Gijsbert M. KalisvaartRichard E. EvenhuisWillem GrootjansThomas Van Den BergheMartijn CallensJudith V. M. G. BovéeDavid CreytensHans GelderblomFrank M. SpeetjensLore Lapeire et al.

A1 Journal Article in CANCERS

Sexual satisfaction and its predictors in patients with advanced cancer and their family caregivers in six European countries : baseline data from the DIAdIC study

Orphé MatthysSigrid DierickxVincent Van GoethemLuc DeliensLore LapeireAglaja De PauwPeter HudsonChristof VulstekeKaren GeboesStefanie De Waele et al.

A1 Journal Article in PSYCHO-ONCOLOGY

2023

A self-management psychoeducational eHealth program to support and empower people with advanced cancer and their family caregivers : development using the scrum methodology

Vincent Van GoethemSigrid DierickxOrphé MatthysLaurel NorthouseLine LundCatherine JordanElena TurolaMaaike van der WelDavid ScottRichard Harding et al.

A1 Journal Article in INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH

Advance care planning : family carer psychological distress and involvement in decision making : the ACTION trial

Isabel VandenbogaerdeAline De VleminckJoachim CohenMariette VerkissenLore LapeireFrancesca IngravalloSheila PayneAndrew WilcockJane SeymourMarijke Kars et al.

A1 Journal Article in BMJ SUPPORTIVE & PALLIATIVE CARE

High-grade endometrial stromal sarcoma-like sarcoma in male : does it exist? A case report and review of the literature

Fleur CordierJoni Van der MeulenSiebe LoontiensNadine Van RoyLore LapeireWouter WillaertLiesbeth FerdinandeKoen Van de VijverJo Van DorpeDavid Creytens

A1 Journal Article in PATHOLOGY RESEARCH AND PRACTICE

Incidence, evolution and risk factors of hypophosphatemia in patients with solid tumors receiving ferric carboxymaltose : a retrospective cohort study

Alexander DecruyenaereKoen KortbeekSigurd DelangheSylvie RotteyHannelore DenysLore Lapeire

A1 Journal Article in ACTA CLINICA BELGICA

Is pre-bereavement collaboration between family caregivers and healthcare professionals associated with post-bereavement emotional well-being? A population-based survey

Orphé MatthysSigrid DierickxLuc DeliensLore LapeirePeter HudsonChantal Van AudenhoveAline De VleminckJoachim Cohen

A1 Journal Article in PATIENT EDUCATION AND COUNSELING

Post‐operative minimal residual disease models to study metastatic relapse in soft‐tissue sarcoma patient‐derived xenografts

Suzanne FischerDavid CreytensSofie De GeyterElly De VliegherePiet PattynSarah-Lee BekaertKaat DurinckNadine Van RoyAn HendrixLore Lapeire et al.

A1 Journal Article in CLINICAL AND TRANSLATIONAL MEDICINE

Size and characteristics of family caregiving for people with serious illness : a population-based survey

Vincent Van GoethemSigrid DierickxLuc DeliensAline De VleminckLore LapeireJoachim Cohen

A1 Journal Article in PALLIATIVE & SUPPORTIVE CARE

The impact of systemic oncological treatments on the fertility of adolescents and young adults : a systematic review

Justine HimpeSander LammerantLore Van den BerghLore LapeireChloë De Roo

A1 Journal Article in LIFE-BASEL

2022

A tailored psychosocial support tool for parents of adolescents and young adults with cancer

Nathalie BelpameElsie DecoeneMARIJKE QUAGHEBEURLore LapeireSofie Verhaeghe

Diagnosis of epithelioid hemangioendothelioma 8 days postpartum : is there a link with pregnancy? : A case report and review of the literature

Nicky SomersDavid CreytensSimon Van BelleGwen SysLore Lapeire

A1 Journal Article in ACTA CLINICA BELGICA

How are family caregivers of people with a serious illness supported by healthcare professionals in their caregiving tasks? A cross-sectional survey of bereaved family caregivers

Orphé MatthysSigrid DierickxLuc DeliensLore LapeirePeter HudsonChantal Van AudenhoveAline De VleminckJoachim Cohen

A1 Journal Article in PALLIATIVE MEDICINE

Identification of the most important factors related to people with cancer starting a palliative care conversation : a survey study

Anne-Lore ScherrensKim BeernaertLuc DeliensLore LapeireMartine De LaatChristine BiebuyckKaren GeboesCharles Van PraetIne MoorsBenedicte Deforche et al.

A1 Journal Article in PSYCHO-ONCOLOGY

Imaging findings and value of CT and (DCE-)MRI in monitoring denosumab therapy of giant cell tumors of bone

Thomas Van Den BergheMaryse LejolyLore LapeireWouter HuysseDavid CreytensKoenraad Verstraete

Imaging findings and value of CT and DCE-MRI in monitoring denosumab therapy of giant cell tumors of bone

Thomas Van Den BergheLore LapeireMaryse LejolyWouter HuysseDavid CreytensKoenraad Verstraete

Mental health and quality of life among patients with cancer during the SARS-CoV-2 pandemic : results from the longitudinal ONCOVID survey study

Emiel De JaeghereHeini KanervoRoos ColmanWim SchrauwenPaulien WestNele VandemaeleAglaja De PauwCeline JacobsIngeborg HildersonMichael Saerens et al.

A1 Journal Article in CANCERS

Metastasized orthotopic patient-derived xenografts as preclinical model to guide therapeutic decision making in soft tissue sarcoma patients

Suzanne FischerElly De VlieghereDavid CreytensOlivier De WeverAn HendrixLore LapeireGwen Sys

Undifferentiated sarcoma of bone with a round to epithelioid cell phenotype harboring a novel EWSR1-SSX2 fusion identified by RNA-based next-generation sequencing

Fleur CordierJoni Van der MeulenBram Van GaeverLore LapeireGwen SysJo Van DorpeDavid Creytens

A1 Journal Article in GENES CHROMOSOMES & CANCER

2021

A challenging case of a poorly differentiated small cell variant of synovial sarcoma with unusual immunophenotype

Fleur CordierLore LapeireGwen SysJo Van DorpeDavid Creytens

A1 Journal Article in PATHOLOGY

A tailored psychosocial support tool for parents of AYAs with cancer and AYA survivors

Nathalie BelpameElsie DecoeneMarijke QuaghebeurLore LapeireSofie Verhaeghe

An online platform facilitating peer-to-peer support for AYAs in Belgium : a Care4AYA intervention

Nathalie BelpameElsie DecoeneMarijke QuaghebeurSofie VerhaegheLore Lapeire

An undifferentiated sarcoma of bone with a round to epithelioid cell phenotype harboring a novel EWSR1-SSX2 fusion identified by RNA-based next-generation sequencing

Fleur CordierJoni Van der MeulenBram Van GaeverLore LapeireGwen SysJo Van DorpeDavid Creytens

Nathalie BelpameElsie DecoeneMARIJKE QUAGHEBEURHans NeefsLore Lapeire

Immune checkpoint inhibitors in treatment of soft-tissue sarcoma : a systematic review and meta-analysis

Michael SaerensNele BrusselaersSylvie RotteyAlexander DecruyenaereDavid CreytensLore Lapeire

A1 Journal Article in EUROPEAN JOURNAL OF CANCER

Late lung metastasis in a patient with a clear cell chondrosarcoma : an indication for a life-long follow-up?

Paulien WestCeline JacobsMicky SaerensDavid CreytensGwen SysLore Lapeire

A2 Journal Article in CASE REPORTS IN ONCOLOGICAL MEDICINE

Longitudinal CT and MR evaluation of denosumab therapy in giant cell tumours of bone

Thomas Van Den BergheMaryse LejolyLore LapeireWouter HuysseDavid CreytensKoenraad Verstraete

NGS-analysis to the rescue : dual checkpoint inhibition in metastatic osteosarcoma : a case report and review of the literature

Laure NuytemansGwen SysDavid CreytensLore Lapeire

A1 Journal Article in ACTA CLINICA BELGICA

Patient-derived cell lines and xenografts from sarcoma patients as models for therapeutic decision making

Suzanne FischerDavid CreytensGwen SysLore LapeireAn HendrixOlivier De Wever

Spindle cell/sclerosing rhabdomyosarcoma with a novel YAP1-MAML2 fusion in a 1-year-old : not all strongly TRK-expressing spindle cell sarcomas in infants are infantile fibrosarcomas!

Fleur CordierEline AmelootCatharina DhoogeLore LapeireGwen SysJo Van DorpeDavid Creytens

A1 Journal Article in PATHOLOGY

Towards specialized age-appropriate care in Ghent, Belgium : the development, implementation and evaluation of a transmural AYA care pathway

Nathalie BelpameHans NeefsElsie DecoeneMarijke QuaghebeurLore LapeireSofie Verhaeghe

2020

A phase 1 study of mTORC1/2 inhibitor BI 860585 as a single agent or with exemestane or paclitaxel in patients with advanced solid tumors

Filippo de BraudJean-Pascal H. MachielsDaniela BoggianiSylvie RotteyMatteo DucaMarie LaruelleStefania SalvagniSilvia DamianLore LapeireMarcello Tiseo et al.

A1 Journal Article in CANCERS

Integration of oncology and palliative care: summary of the Lancet Oncology Commission Paper.

Naomi DhollanderLuc DeliensStein KaasaJH LogeT LundebyLore LapeireKim Beernaert

A2 Journal Article in BELGIAN JOURNAL OF MEDICAL ONCOLOGY

Is early integration of palliative home care in oncology treatment feasible and acceptable for advanced cancer patients and their health care providers? A phase 2 mixed-methods study

Naomi DhollanderTinne SmetsAline De VleminckLore LapeireKoen PardonLuc Deliens

A1 Journal Article in BMC PALLIATIVE CARE

2019

Algorithms for molecular testing in solid tumours

A. HébrantM. LammensC. Van den BroeckeN. D’HaeneJ. Van den OordA. VandersticheleA. DendoovenP. NevenK. PunieG. Floris et al.

A2 Journal Article in BELGIAN JOURNAL OF MEDICAL ONCOLOGY

Establishment of 6 novel patient-derived sarcoma cell lines and 1 patient-derived carcinosarcoma cell line

Suzanne FischerDavid CreytensLore LapeireAn HendrixPiet PattynGwen Sys

NBTXR3, a first-in-class radioenhancer hafnium oxide nanoparticle, plus radiotherapy versus radiotherapy alone in patients with locally advanced soft-tissue sarcoma (Act. In. Sarc) : a multicentre, phase 2-3, randomised, controlled trial

Sylvie BonvalotPiotr L RutkowskiJuliette ThariatSebastien CarrereAnne DucassouMarie-Pierre SunyachPeter AgostonAngela HongAugustin MervoyerMarco Rastrelli et al.

A1 Journal Article in LANCET ONCOLOGY

Specifieke zorg voor jongeren met kanker : aanbevelingen uit kwalitatief onderzoek

Nathalie BelpameLore LapeireSofie Verhaeghe

A2 Journal Article in HUISARTS NU

2018

Establishment of novel patient-derived sarcoma cell lines : preliminary results

Suzanne FischerDavid CreytensLore LapeireGwen Sys

2017

Care4AYA, interventions in a university hospital in Belgium

Nathalie BelpameElsie DecoeneJohan De MunterLore LapeireVeronique Van de VeldeMarijke Quaghebeur

Secretome analysis of breast cancer-associated adipose tissue to identify paracrine regulators of breast cancer growth

Lore LapeireAn HendrixEvelyne LecoutereMieke Van BockstalJo VandesompeleDawn MaynardGeert BraemsRudy Van den BroeckeCathérine MüllerMarc Bracke et al.

A1 Journal Article in ONCOTARGET

The isolation of morphologically intact and biologically active extracellular vesicles from the secretome of cancer-associated adipose tissue

Sarah JeurissenGlenn VergauwenJan Van DeunLore LapeireVictoria DepoorterIlkka MiinalainenRaija SormunenRudy Van den BroeckeGeert BraemsVeronique Cocquyt et al.

A1 Journal Article in CELL ADHESION & MIGRATION

2016

Phase I study of mTORC1/2 inhibitor BI 860585 as single agent or with exemestane or paclitaxel in patients with advanced solid tumors

Filippo G De BraudJean-Pascal H MachielsMarcello TiseoSylvie RotteyMatteo DucaMarie LaruelleStefania SalvagniLore LapeireLaura ManfredaCeline Veau et al.

2015

When fat becomes an ally of the enemy : adipose tissue as collaborator in human breast cancer

Lore LapeireHannelore DenysVeronique CocquytOlivier De Wever

A2 Journal Article in HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION

When the fat (lady) starts to sing : the role of adipose tissue secreted factors in breast cancer progression

Lore LapeireVeronique CocquytOlivier De Wever

2014

Cancer-associated adipose tissue promotes breast cancer progression by paracrine Oncostatin M and Jak/STAT3 signaling

Lore LapeireAn HendrixKathleen LambeinMieke Van BockstalGeert BraemsRudy Van den BroeckeRIDHA LIMAMEPieter MestdaghJo VandesompeleChristian Vanhove et al.

A1 Journal Article in CANCER RESEARCH

Cancer-associated adipose tissue promotes breast cancer progression by paracrine Oncostatin M and JAK3/STAT3 signaling

Lore LapeireAn HendrixKathleen LambeinMieke Van BockstalGeert BraemsRudy Van den BroeckeRidha LimamePieter MestdaghJo VandesompeleChristian Vanhove et al.

2013

The in ovo CAM-assay as a xenograft model for sarcoma

Gwen SysLore LapeireNikita StevensHerman FavoreelRamses ForsythMarc BrackeOlivier De Wever

A1 Journal Article in JOVE-JOURNAL OF VISUALIZED EXPERIMENTS

2012

De plaats van cetuximab in de behandeling van hoofd- en halstumoren

Lore LapeirePhilippe DeronFréderic DuprezSylvie Rottey

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Neoplasm related encephalopathies

Lore LapeireAnne SiebenPatrick SantensSimon Van Belle

Bookchapter in Miscellanea on encephalopathies : a second look

2011

Adipose tissue in breast cancer : not an idle bystander but an active participant in breast cancer progression

Lore LapeireAn HendrixKathleen LambeinGeert BraemsP ValetRudy Van den BroeckeMarc BrackeVeronique CocquytHannelore DenysOlivier De Wever

2010

Carcinoid encephalopathy: a single entity or a spectrum of different disorders?

Lore LapeireANNELEEN TANSENSGilbert LemmensSimon Van Belle

A1 Journal Article in ACTA ONCOLOGICA

Cellular and molecular mechanisms of cancer cell invasion

Olivier De WeverLore LapeireAstrid De BoeckAn Hendrix

A4 Journal Article in VERHANDELINGEN VAN DE KONINKLIJKE ACADEMIE VOOR GENEESKUNDE VAN BELGIË

2009

Intermittent psychiatric syndrome in a patient with carcinoid tumour

ANNELEEN TANSENSLore LapeireGERD VANDONINCKGilbert LemmensKurt AudenaertSimon Van Belle

Mitoxantronchemotherapie voor de behandeling van multiple sclerose

Lore LapeireJan DebruyneSylvie Rottey

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE