Research Explorer

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Researcher

Lore Billiet

Awards & Distinctions

12 Results

2024

From thymus to periphery : unraveling the complexity of human polyclonal unconventional αβ T cells

Lore BillietBart VandekerckhoveTessa Kerre

Knocking out CD70 rescues CD70-specific nanoCAR T cells from antigen-induced exhaustion

Stijn De MunterJuliane L. BuhlLaurenz De CockAlexander Van ParysWillem DaneelsEva PascalLucas DeseinsJoline IngelsGlenn GoetgelukHanne Jansen et al.

A1 Journal Article in CANCER IMMUNOLOGY RESEARCH

Neoantigen-targeted dendritic cell vaccination in lung cancer patients induces long-lived T cells exhibiting the full differentiation spectrum

Joline IngelsLaurenz De CockDieter StevensRupert MayerFabien Henri TheryGuillem Sanchez SanchezDavid VermijlenKarin WeeningSASKIA DE SMETNELE LOOTENS et al.

A1 Journal Article in CELL REPORTS MEDICINE

ThymoSpheres culture : a model to study human polyclonal unconventional T cells

Lore BillietHanne JansenMelissa PilleLena BöhmeGuillem Sanchez SanchezLaurenz De CockGlenn GoetgelukEva PascalStijn De MunterLucas Deseins et al.

A1 Journal Article in EUROPEAN JOURNAL OF IMMUNOLOGY

2023

Knocking out CD70 rescues CD70-specific nanoCAR T cells from antigen induced exhaustion

Stijn De MunterJuliane BuhlLaurenz De CockAlexander Van ParysWillem DaneelsEva PascalLucas DeseinsJoline IngelsGlenn GoetgelukLore Billiet et al.

Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage

Lore BillietLaurenz De CockGuillem Sanchez SanchezRupert MayerGlenn GoetgelukStijn De MunterMelissa PilleJoline IngelsHanne JansenKarin Weening et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

The Wiskott–Aldrich syndrome protein is required for positive selection during T-cell lineage differentiation

Melissa PilleJohn AvilaGuillem Sanchez SanchezGlenn GoetgelukStijn De MunterHanne JansenLore BillietKarin WeeningHaipeng XueSarah Bonte et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2022

Small-scale manufacturing of neoantigen-encoding messenger RNA for early-phase clinical trials

Joline IngelsLaurenz De CockRupert MayerPam DevrekerKarin WeeningKelly HeynsNele LootensSaskia De SmetMarieke BrusseelStijn De Munter et al.

A1 Journal Article in CYTOTHERAPY

2021

In vitro OP9-DL1 co-culture and subsequent maturation in the presence of IL-21 generates tumor antigen-specific T cells with a favorable less-differentiated phenotype and enhanced functionality

Sarah BonteStijn De MunterLore BillietGlenn GoetgelukJoline IngelsHanne JansenMelissa PilleLaurenz De CockKarin WeeningTom Taghon et al.

A1 Journal Article in ONCOIMMUNOLOGY

2020

Human thymic CD10+ PD-1+ intraepithelial lymphocyte precursors acquire interleukin-15 responsiveness at the CD1a– CD95+ CD28– CCR7– developmental stage

Lore BillietGlenn GoetgelukSarah BonteStijn De MunterLaurenz De CockMelissa PilleJoline IngelsHanne JansenKarin WeeningFilip Van Nieuwerburgh et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Rapid and effective generation of nanobody based CARs using PCR and Gibson Assembly

Stijn De MunterAlexander Van ParysLayla BralJoline IngelsGlenn GoetgelukSarah BonteMelissa PilleLore BillietKarin WeeningAnnick Verhee et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

T-cells with a single tumor antigen-specific T-cell receptor can be generated in vitro from clinically relevant stem cell sources

Sarah BonteStijn De MunterGlenn GoetgelukJoline IngelsMelissa PilleLore BillietTom TaghonGeorges LeclercqBart VandekerckhoveTessa Kerre

A1 Journal Article in ONCOIMMUNOLOGY