Research Explorer

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Researcher

Lode De Cauwer

17 Results

2019

Mechanisms underlying the functional cooperation between PPARα and GRα to attenuate inflammatory responses

Nadia BougarneViacheslav MylkaDariusz RatmanIlse BeckJonathan ThommisLode De CauwerJan TavernierBart StaelsClaude LibertKarolien De Bosscher

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2018

Biallelic and monoallelic ESR2 variants associated with 46,XY disorders of sex development

Dorien BaetensTülay GüranBerenice B MendoncaNathalia L GomesLode De CauwerFrank PeelmanHannah VerdinMarnik VuylstekeMalaïka Van Der LindenHans StoopLeendert H LooijengaKarolien De BosscherMartine CoolsElfride De Baerethe ESR2 study groupKatleen De Preter

A1 Journal Article in GENETICS IN MEDICINE

Co-activation of glucocorticoid receptor and peroxisome proliferator-activated receptor-γ in murine skin prevents worsening of atopic march

Julie DeckersNadia BougarneViacheslav MylkaSofie DesmetAstrid LuypaertMichael DevosGiel TangheJustine Van MoorleghemManon VanheerswynghelsLode De CauwerJonathan ThommisMarnik VuylstekeJan TavernierBart LambrechtHamida HammadKarolien De Bosscher

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

The autophagy receptor SQSTM1/p62 mediates anti-inflammatory actions of the selective NR3C1/glucocorticoid receptor modulator compound A (CpdA) in macrophages

Viacheslav MylkaJulie DeckersDariusz RatmanLode De CauwerJonathan ThommisRiet De RyckeFrancis ImpensClaude LibertJan TavernierWim Vanden BergheKris GevaertKarolien De Bosscher

A1 Journal Article in AUTOPHAGY

2017

A safe and highly efficient tumor-targeted type I interferon immunotherapy depends on the tumor microenvironment

Anje CauwelsSandra Van LintGeneviève GarcinJennyfer BultinckFranciane PaulSarah GerloJosé Van Der HeydenYann BordatDominiek CatteeuwLode De CauwerElke RoggeAnnick VerheeGilles UzéJan Tavernier

A1 Journal Article in ONCOIMMUNOLOGY

Compound A influences gene regulation of the dexamethasone-activated glucocorticoid receptor by alternative cofactor recruitment

Sofie DesmetNadia BougarneLaura Van MoortelLode De CauwerJonathan ThommisM VuylstekeDariusz RatmanR HoutmanJan TavernierKarolien De Bosscher

A1 Journal Article in SCIENTIFIC REPORTS

Glucocorticoid receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor

Ioanna PettaNadia BougarneJolien VandewalleLien DejagerSofie VandevyverMarlies BallegeerSofie DesmetJonathan ThommisLode De CauwerSam LievensClaude LibertJan TavernierKarolien De Bosscher

A1 Journal Article in SCIENTIFIC REPORTS

Plasmodium berghei NK65 in combination with IFN-γ induces endothelial glucocorticoid resistance via sustained activation of p38 and JNK

Karolina A. ZielińskaLode De CauwerSofie KnoopsKristof Van der MolenAlexander SneyersJonathan ThommisJ. Brian De SouzaGhislain OpdenakkerKarolien De BosscherPhilippe E. Van den Steen

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

TYK2-induced phosphorylation of Y640 suppresses STAT3 transcriptional activity

Raffaele MoriJoris WaumanLaura IcardiJosé Van Der HeydenLode De CauwerFrank PeelmanKarolien De BosscherJan Tavernier

A1 Journal Article in SCIENTIFIC REPORTS

The nature of the GRE influences the screening for GR-activity enhancing modulators

Karen DendonckerSteven TimmermansKelly Van LooverenLode De CauwerKarolien De BosscherClaude Libert

A1 Journal Article in PLOS ONE

2016

Chromatin recruitment of activated AMPK drives fasting response genes co-controlled by GR and PPARα

Dariusz RatmanViacheslav MylkaNadia BougarneMichal PawlakSandrine CaronNathalie HennuyerRéjane PaumelleLode De CauwerJonathan ThommisMark H RiderClaude LibertSam LievensJan TavernierBart StaelsKarolien De Bosscher

A1 Journal Article in NUCLEIC ACIDS RESEARCH

2015

Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice

Robrecht ThoonenAnje CauwelsKelly DecaluwéSandra GeschkaRobert E TainshJoris DelangheTino HochepiedLode De CauwerElke RoggeSofie VoetPatrick SipsRichard H KarasKenneth D BlochMarnik VuylstekeJohannes-Peter StaschJohan Van de VoordeEmmanuel S BuysPeter Brouckaert

A1 Journal Article in NATURE COMMUNICATIONS

2014

Heme-deficient NO-unresponsive sGC knock-in mice: novel aspects of NO sGC signaling in cardiovascular (patho)physiology

Robrecht ThoonenEmmanuel BuysAnje CauwelsKelly DecaluwéSandra GeschkaRobert TainshJoris DelangheTino HochepiedLode De CauwerElke RoggePatrick SipsRichard KarasKenneth BlochJohan Van de VoordeJohannes-Peter StaschMarnik VuylstekePeter Brouckaert

2012

A dissociated glucocorticoid receptor modulator reduces airway hyperresponsiveness and inflammation in a mouse model of asthma

Laurent L ReberFrançois DaubeufMaud PlantingaLode De CauwerSarah GerloWim WaelputSerge Van CalenberghJan TavernierGuy HaegemanBart LambrechtNelly FrossardKarolien De Bosscher

A1 Journal Article in JOURNAL OF IMMUNOLOGY

Opposed regulation of type I IFN-induced STAT3 and ISGF3 transcriptional activities by histone deacetylases (HDACS) 1 and 2

Laura IcardiSam LievensRaffaele MoriJulie PiessevauxLode De CauwerKarolien De BosscherJan Tavernier

A1 Journal Article in FASEB JOURNAL

The Sin3a repressor complex is a master regulator of STAT transcriptional activity

Laura IcardiRaffaele MoriViola GesellchenSven EyckermanLode De CauwerJudith VerhelstKoen VercauterenXavier SaelensPhilip MeulemanGeert Leroux-RoelsKarolien De BosscherMichael BoutrosJan Tavernier

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2011

Opposite regulation of type I IFN-induced STAT3 and ISGF3 transcriptional activities by histone deacetylases (HDACS) 1 and 2

Laura IcardiKarolien De BosscherRaffaele MoriLode De CauwerSam LievensJan Tavernier