Research Explorer

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Researcher

Lisa Ostyn

Awards & Distinctions

13 Results

2025

Combination of phages and antibiotics with enhanced killing efficacy against dual-species bacterial communities in a three-dimensional lung epithelial model

Ergun AkturkGraca PintoLisa OstynAurélie CrabbéLuis D. R. MeloJoana AzeredoTom Coenye

A2 Journal Article in BIOFILM

2024

Genome-scale model of Rothia mucilaginosa predicts gene essentialities and reveals metabolic capabilities

Nantia LeonidouLisa OstynTom CoenyeAurélie CrabbéAndreas Dräger

A1 Journal Article in MICROBIOLOGY SPECTRUM

2023

Direct lysis of 3D cell cultures for RT-qPCR gene expression quantification

Fien GysensLisa OstynEllen GoeteynEva BlondeelJustine NuytensOlivier De WeverEric de Bony de LavergneAurélie CrabbéPieter Mestdagh

A1 Journal Article in SCIENTIFIC REPORTS

The development and characterization of in vivo-like three-dimensional models of bronchial epithelial cell lines.

Sara Van den BosscheLisa OstynValerie VandendriesscheCharlotte RigautsHerlinde De KeersmaeckerCheryl A. NickersonAurélie Crabbé

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

2022

Microbial diversity and antimicrobial susceptibility in endotracheal tube biofilms recovered from mechanically ventilated COVID-19 patients

Frits van CharanteAnneleen WiemePetra RigoleEvelien De CanckLisa OstynLucia GrassiDieter DeforceAurélie CrabbéPeter VandammeMarie Joossens et al.

A2 Journal Article in BIOFILM

Rothia mucilaginosa is an anti-inflammatory bacterium in the respiratory tract of patients with chronic lung disease

Charlotte RigautsJuliana AizawaSteven TaylorGeraint B. RogersMatthias GovaertsPaul CosLisa OstynSarah SimsEva VandeplasscheMozes Sze et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

2020

Antibiotic susceptibility of cystic fibrosis lung microbiome members in a multispecies biofilm

Eva VandeplasscheAndrea SassLisa OstynMette BurmølleKasper Nørskov KraghThomas BjarnsholtTom CoenyeAurélie Crabbé

A2 Journal Article in BIOFILM (AMSTERDAM)

Bacterial interference with lactate dehydrogenase assay leads to an underestimation of cytotoxicity

Sara Van den BosscheEva VandeplasscheLisa OstynTom CoenyeAurélie Crabbé

A1 Journal Article in FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY

2019

Host metabolites stimulate the bacterial proton motive force to enhance the activity of aminoglycoside antibiotics

Aurélie CrabbéLisa OstynSorien StaelensCharlotte RigautsMartijn RisseeuwMaarten DhaenensSimon DaledHeleen Van AckerDieter DeforceSerge Van Calenbergh et al.

A1 Journal Article in PLOS PATHOGENS

The antimicrobial peptide lin-SB056-1 and its dendrimeric derivative prevent Pseudomonas aeruginosa biofilm formation in physiologically relevant models of chronic infections

Lucia GrassiGiovanna BatoniLisa OstynPetra RigoleSara Van den BosscheAndrea C RinaldiGiuseppantonio MaisettaSemih EsinTom CoenyeAurélie Crabbé

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

The role of small proteins in Burkholderia cenocepacia J2315 biofilm formation, persistence and intracellular growth

Heleen Van AckerAurélie CrabbéDukas JurėnasLisa OstynAndrea SassSimon DaledMaarten DhaenensDieter DeforceEline TeirlinckHerlinde De Keersmaecker et al.

A2 Journal Article in BIOFILM

Various Evolutionary Trajectories Lead to Loss of the Tobramycin-Potentiating Activity of the Quorum-Sensing Inhibitor Baicalin Hydrate in Burkholderia cenocepacia Biofilms

Andrea SassLisa SlachmuyldersHeleen Van AckerIan VandenbusscheLisa OstynMona BovéAurélie CrabbéLaurent R ChiarelliSilvia BuroniFilip Van Nieuwerburgh et al.

A1 Journal Article in ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

2018

Influence of three-dimensional lung epithelial cells and interspecies interactions on antibiotic efficacy against Mycobacterium abscessus and Pseudomonas aeruginosa

Graciela Rodriguez-SevillaCharlotte RigautsEva VandeplasscheLisa OstynIgnacio Mahillo-FernandezJaime EstebanConcepcion Perez-Jorge PeremarchTom CoenyeAurélie Crabbé

A1 Journal Article in PATHOGENS AND DISEASE