Research Explorer

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Researcher

Lisa Opsomer

Awards & Distinctions

7 Results

2024

Amplification of Protein Expression by Self-Amplifying mRNA Delivered in Lipid Nanoparticles Containing a β-Aminoester Ionizable Lipid Correlates with Reduced Innate Immune Activation

Emily De LombaerdeXiaole CuiYong ChenZifu ZhongJulie DeckersGiulia MencarelliLisa OpsomerHaixiu WangJamie De BaereStefan Lienenklaus et al.

U Journal Article in ACS NANO

Efficient in vitro and in vivo transfection of self-amplifying mRNA with linear poly(propylenimine) and poly(ethylenimine-propylenimine) random copolymers as non-viral carriers

Lisa OpsomerSomdeb JanaIne MertensXiaole CuiRichard HoogenboomNiek Sanders

A1 Journal Article in JOURNAL OF MATERIALS CHEMISTRY B

2023

Novel polymers as promising non-viral carriers for self-amplifying mRNA-based applications

Lisa OpsomerSomdeb JanaIne MertensRichard HoogenboomNiek Sanders

Stability study of self-amplifying mRNA-based polyplexes

Lisa OpsomerSomdeb JanaRichard HoogenboomNiek Sanders

2022

Linear (PEI-)PPI-based (co-)polymers as promising alternative carrier platform for RNA-based vaccines and therapeutics

Novel promising PPI and PEI-PPI based polymeric carriers for sa-mRNA vaccines

2021

Corticosteroids and cellulose purification improve, respectively, the in vivo translation and vaccination efficacy of sa-mRNAs

Zifu ZhongSéan Mc CaffertyLisa OpsomerHaixiu WangHanne HuysmansJoyca De TemmermanStefan LienenklausJoão Portela CataniFrancis CombesNiek Sanders

A1 Journal Article in MOLECULAR THERAPY