Research Explorer

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Researcher

Lisa De Witte

Awards & Distinctions

6 Results

2023

Retained chromosomal integrity following CRISPR-Cas9-based mutational correction in human embryos

Bieke BekaertAnnekatrien BoelLisa De WitteWinter VandenbergheMina PopovicPanagiotis StamatiadisGwenny CosemansLise TordeursAthina-Maria De LooreSusana Marina Chuva de Sousa Lopes et al.

A1 Journal Article in MOLECULAR THERAPY

2022

CRISPR/Cas gene editing in the human germline

Bieke BekaertAnnekatrien BoelGwenny CosemansLisa De WitteBjörn MentenBjörn Heindryckx

A1 Journal Article in SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Distinct genetic impact of CRISPR/Cas9 gene correction in human embryos compared to induced pluripotent stem cells

Bieke BekaertAnnekatrien BoelLisa De WitteGwenny CosemansLise TordeursAthina-Maria De LooreSusana Marina Chuva de Sousa LopesPetra De SutterDominic StoopPaul Coucke et al.

Evaluation of CRISPR/Cas9-induced DNA break repair outcomes in mouse and human embryos

Bieke BekaertAnnekatrien BoelLisa De WitteGwenny CosemansSusana Marina Chuva de Sousa LopesBjörn MentenBjörn Heindryckx

GENType : all-in-one preimplantation genetic testing by pedigree haplotyping and copy number profiling suitable for third-party reproduction

Lisa De WitteLennart RamanMachteld BaetensAndries De KokerNico CallewaertSofie SymoensKelly TillemanFrauke Vanden MeerschautAnnelies DheedeneBjörn Menten

A1 Journal Article in HUMAN REPRODUCTION

2020

A proof-of-concept study to investigate DNA repair mechanisms in the human embryo after the application of CRISPR/Cas9 gene editing in the germ line

Bieke BekaertAnnekatrien BoelLisa De WitteMina PopovicRamesh GuggillaSwati MishraGwenny CosemansLise TordeursSusana Marina Chuva de Sousa LopesPetra De Sutter et al.