Research Explorer

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Researcher

Lisa De Witte

Awards & Distinctions

7 Results

2024

Aligning genotyping and copy number data in single trophectoderm biopsies for aneuploidy prediction : uncovering incomplete concordance

Lisa De WitteMachteld BaetensKelly TillemanFrauke Vanden MeerschautSandra JanssensAriane Van TongerlooVirginie SzymczakDominic StoopAnnelies DheedeneSofie Symoens et al.

A1 Journal Article in HUMAN REPRODUCTION OPEN

2023

Retained chromosomal integrity following CRISPR-Cas9-based mutational correction in human embryos

Bieke BekaertAnnekatrien BoelLisa De WitteWinter VandenbergheMina PopovicPanagiotis StamatiadisGwenny CosemansLise TordeursAthina-Maria De LooreSusana Marina Chuva de Sousa Lopes et al.

A1 Journal Article in MOLECULAR THERAPY

2022

CRISPR/Cas gene editing in the human germline

Bieke BekaertAnnekatrien BoelGwenny CosemansLisa De WitteBjörn MentenBjörn Heindryckx

A1 Journal Article in SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Distinct genetic impact of CRISPR/Cas9 gene correction in human embryos compared to induced pluripotent stem cells

Bieke BekaertAnnekatrien BoelLisa De WitteGwenny CosemansLise TordeursAthina-Maria De LooreSusana Marina Chuva de Sousa LopesPetra De SutterDominic StoopPaul Coucke et al.

Evaluation of CRISPR/Cas9-induced DNA break repair outcomes in mouse and human embryos

Bieke BekaertAnnekatrien BoelLisa De WitteGwenny CosemansSusana Marina Chuva de Sousa LopesBjörn MentenBjörn Heindryckx

GENType : all-in-one preimplantation genetic testing by pedigree haplotyping and copy number profiling suitable for third-party reproduction

Lisa De WitteLennart RamanMachteld BaetensAndries De KokerNico CallewaertSofie SymoensKelly TillemanFrauke Vanden MeerschautAnnelies DheedeneBjörn Menten

A1 Journal Article in HUMAN REPRODUCTION

2020

A proof-of-concept study to investigate DNA repair mechanisms in the human embryo after the application of CRISPR/Cas9 gene editing in the germ line

Bieke BekaertAnnekatrien BoelLisa De WitteMina PopovicRamesh Reddy GuggillaSwati MishraGwenny CosemansLise TordeursSusana Marina Chuva de Sousa LopesPetra De Sutter et al.