Research Explorer

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Researcher

Lieven Haenebalcke

16 Results

2019

Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies

Tim PietersSara T'SasLisa DemoenAndré Pedro Pinto De AlmeidaLieven HaenebalckeFilip MatthijssensKelly LemeireJinke D'HontFrédérique VanrockeghemTino HochepiedBéatrice LintermansLindy ReunesTim LammensGeert BerxSteven GoossensPieter Van Vlierberghe

A1 Journal Article in SCIENTIFIC REPORTS

2017

Structure-function studies in mouse embryonic stem cells using recombinase-mediated cassette exchange

Tim PietersLieven HaenebalckeKenneth BruneelNiels VandammeTino HochepiedJolanda van HengelGeert BerxFrans Van RoySteven Goossens

A1 Journal Article in JOVE-JOURNAL OF VISUALIZED EXPERIMENTS

2016

Fast generation of conditional ROSA26-based mouse models that recapitulate genomic events in human T-ALL

Tim PietersSteven GoossensSara T'SasLieven HaenebalckeTino HochepiedBéatrice LintermansSofie PeirsFilip MatthijssensGeert BerxPieter Van Vlierberghe

p120 Catenin-mediated stabilization of E-cadherin is essential for primitive endoderm specification

Tim PietersSteven GoossensLieven HaenebalckeVanessa AndriesRiet De RyckeKelly LemeireTino HochepiedGeert BerxJody HaighJolanda van HengelFrans Van Roy

A1 Journal Article in PLOS GENETICS

2015

Strategies to rescue the consequences of inducible arginase-1 deficiency in mice

Steven GoossensLieven HaenebalckeJody Haigh

A1 Journal Article in PLOS ONE

ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling

Steven GoossensKaat DurinckJoni Van der MeulenSofie PeirsTom TaghonJelle De MedtsSona BartunkovaNatalie FarlaTim PietersFilip MatthijssensNadine Van RoyKim DeswarteLieven HaenebalckePieter RondouKarolina SlowickaGeert BerxFranki SpelemanPieter Van VlierbergheJody Haigh

A1 Journal Article in NATURE COMMUNICATIONS

2014

Loss of autocrine endothelial-derived VEGF significantly reduces hemangiosarcoma development in conditional p53-deficient mice

Morvarid Farhang GhahremaniKatharina HaighSona BartunkovaLieven HaenebalckeJean-Christophe MarineSteven GoossensJody Haigh

A1 Journal Article in CELL CYCLE

2013

Cre/loxP-transgenics

Lieven HaenebalckeJody Haigh

Bookchapter in Brenner’s encyclopedia of genetics, vol. 2

Efficient ROSA26-based conditional and/or inducible transgenesis using RMCE-compatible F1 hybrid mouse embryonic stem cells

Lieven HaenebalckeSteven GoossensMichaël NaessensMorvarid Farhang GhahremaniSona BartunkovaKatharina HaighTim PietersPieterjan DierickxBenjamin DrogatJody Haigh

A1 Journal Article in STEM CELL REVIEWS AND REPORTS

The ROSA26-iPSC mouse : a conditional, inducible, and exchangeable resource for studying cellular (de)differentiation

Lieven HaenebalckeSteven GoossensPieterjan DierickxSona BartunkovaJinke D'HontKatharina HaighTino HochepiedJody Haigh

A1 Journal Article in CELL REPORTS

p53 promotes VEGF expression and angiogenesis in the absence of an intact p21-Rb pathway

Morvarid Farhang GhahremaniSteven GoossensSona BartunkovaPaco HulpiauKatharina HaighLieven HaenebalckeBenjamin DrogatJean-Christophe MarineJody Haigh

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

2012

Efficient and user-friendly pluripotin-based derivation of mouse embryonic stem cells

Tim PietersLieven HaenebalckeTino HochepiedJinke D'HontJody HaighFrans Van RoyJolanda van Hengel

A1 Journal Article in STEM CELL REVIEWS AND REPORTS

Generation and use of novel ROSA26-based ESC/iPSC technologies to study cellular reprogramming and gene function during lineage-directed differentiation

Lieven HaenebalckeJody HaighAnne De Paepe

2011

The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization

Steven GoossensSona BartunkovaBenjamin DrogatKatharina HaighPieter BogaertLieven HaenebalckeGeert BerxJody Haigh

A1 Journal Article in BLOOD

2010

Increased skeletal VEGF enhances β-catenin activity and results in excessively ossified bones

Steven GoossensSona BartunkovaBenjamin DrogatKatharina HaighMichaël NaessensLieven HaenebalckeJody Haigh

A1 Journal Article in EMBO JOURNAL

2009

Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells

Michaël NaessensKatharina HaighAgnieszka GembarskaSteven GoossensSarah De ClercqBenjamin DrogatLieven HaenebalckeSona BartunkovaBram De CraeneMansour KarimiGeert BerxPierre HilsonJean-Christophe MarineJody Haigh

A1 Journal Article in NUCLEIC ACIDS RESEARCH